Locally recurrent breast cancer: pulse dose rate brachytherapy for repeat irradiation following lumpectomy-- a second chance to preserve the breast.

Abstract:

PURPOSE:To perform and assess the effectiveness of local excision of recurrent tumor followed by postoperative pulse dose rate (PDR) brachytherapy. MATERIALS AND METHODS:From 1994 to 2000, 17 patients who had small recurrent breast carcinomas after initially undergoing breast-conserving therapy (BCT), which included postoperative radiation therapy, were treated with local tumor excision and PDR brachytherapy. Recurrences occurred at a median time of 50 months (range, 11-208 months) after primary treatment. Eight patients underwent a combination of PDR brachytherapy (total dose range, 12.5-28.0 Gy) and external-beam radiation therapy (EBT) (total dose range, 12-30 Gy). Nine patients underwent radiation therapy with 40.2-50.0-Gy PDR brachytherapy only. The prescribed radiation dose was 0.5-1.0 Gy per pulse. Patients were examined for local tumor control and treatment-related side effects. RESULTS:Twelve of 17 patients had no local tumor at a median follow-up time of 59 months (range, 20-84 months); two of these patients showed signs of having distant disease. One patient died after a cerebral stroke without evidence of tumor. Four women treated with combined EBT and brachytherapy had secondary local tumor recurrences 4, 8, 8, and 11 months after therapy and had to undergo mastectomy. Despite having undergone radiation therapy previously, patients had side effects limited to moderate (grade 1-2) fibrosis. CONCLUSION:Local tumor excision combined with PDR brachytherapy for small local-regional tumor recurrences after primary BCT is feasible and well tolerated and might obviate mastectomy. Preliminary experiences are encouraging. Further studies are required for appropriate patient selection.

journal_name

Radiology

journal_title

Radiology

authors

Resch A,Fellner C,Mock U,Handl-Zeller L,Biber E,Seitz W,Pötter R

doi

10.1148/radiol.2253011913

subject

Has Abstract

pub_date

2002-12-01 00:00:00

pages

713-8

issue

3

eissn

0033-8419

issn

1527-1315

journal_volume

225

pub_type

杂志文章
  • Characteristics and trends of radiology research: a survey of original articles published in AJR and Radiology between 2001 and 2010.

    abstract:PURPOSE:To determine the characteristics and trends of the original articles published in two major American radiology journals, AJR American Journal of Roentgenology (AJR) and Radiology, between 2001 and 2010. MATERIALS AND METHODS:This was a retrospective bibliometric analysis that did not involve human subjects and...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.12111976

    authors: Lim KJ,Yoon DY,Yun EJ,Seo YL,Baek S,Gu DH,Yoon SJ,Han A,Ku YJ,Kim SS

    更新日期:2012-09-01 00:00:00

  • Osteopetrosis: MR characteristics at 1.5 T.

    abstract::Four patients with proved osteopetrosis (three with the infantile malignant form and one with the benign form) were examined with magnetic resonance imaging at 1.5 T. All patients were studied in the coronal and sagittal planes using both short and long repetition time/echo time sequences. The infantile malignant form...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.161.1.3763870

    authors: Rao VM,Dalinka MK,Mitchell DG,Spritzer CE,Kaplan F,August CS,Axel L,Kressel HY

    更新日期:1986-10-01 00:00:00

  • Malignant lesions initially subjected to short-term mammographic follow-up.

    abstract:PURPOSE:To determine whether systematically evaluated criteria for probably benign lesions were actually applied to lesions placed into that category. MATERIALS AND METHODS:A search of the mammography database yielded 295 cases that were initially followed up with short-term interval mammography but eventually receive...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.2231011355

    authors: Rosen EL,Baker JA,Soo MS

    更新日期:2002-04-01 00:00:00

  • Electromagnetic breast imaging: results of a pilot study in women with abnormal mammograms.

    abstract:PURPOSE:To prospectively assess quantitatively the inherent contrast of electromagnetic (EM) properties that can be imaged by using available technology in women with abnormal findings at conventional breast imaging who underwent subsequent biopsy. MATERIALS AND METHODS:The protocol was HIPAA compliant and approved by...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.2432060286

    authors: Poplack SP,Tosteson TD,Wells WA,Pogue BW,Meaney PM,Hartov A,Kogel CA,Soho SK,Gibson JJ,Paulsen KD

    更新日期:2007-05-01 00:00:00

  • Comparison of US and unenhanced multi-detector row CT in patients suspected of having acute appendicitis.

    abstract:PURPOSE:To prospectively compare the diagnostic performance of ultrasonography (US) and unenhanced multi-detector row computed tomography (CT) in patients suspected of having acute appendicitis by using surgery or clinical follow-up as the reference standard. MATERIALS AND METHODS:The institutional review board approv...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.2362040984

    authors: Keyzer C,Zalcman M,De Maertelaer V,Coppens E,Bali MA,Gevenois PA,Van Gansbeke D

    更新日期:2005-08-01 00:00:00

  • Postoperative irradiation of pterygia: ten more years of experience.

    abstract::"Bare sclera" excision followed by 90Sr beta irradiation has been used at Bellevue Hospital for more than 20 years as standard therapy for pterygia. Primary treatment was successful in approximately 90% of cases, and 80% of the failures were salvaged by a second course. This policy is recommended for similar patient p...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/128.3.753

    authors: Cooper JS

    更新日期:1978-09-01 00:00:00

  • Diagnosis of pulmonary embolism: experimental evaluation of the accuracy of scintigraphically guided pulmonary arteriography.

    abstract::Technically refined angiograms and scintigrams were extremely sensitive in demonstrating experimental canine thromboemboli, both immediately after embolization and during the entire course of embolic lysis. Technical refinements included subselective, scintigraphically guided, magnification arteriography and eight-vie...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.136.1.7384490

    authors: Bookstein JJ,Feigin DS,Seo KW,Alazraki NP

    更新日期:1980-07-01 00:00:00

  • The kidney: imaging with Tc-99m mercaptoacetyltriglycine, a technetium-labeled analog of iodohippurate.

    abstract::A new renal imaging agent, technetium-99m mercaptoacetyltriglycine (MAG3, mertiatide), is currently undergoing clinical trials. Like iodine-131 orthoiodohippurate (OIH)--and unlike all other available agents--it is avidly secreted by the renal tubules. Fifty patients underwent simultaneous renal imaging studies with I...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.172.2.2526350

    authors: Russell CD,Thorstad BL,Stutzman ME,Yester MV,Fowler D,Dubovsky EV

    更新日期:1989-08-01 00:00:00

  • Shielding the hand during cross-compression angiography.

    abstract::A simple method of shielding the hand during cross-compression angiography is described. A standard lead glove with the fingertips cut out of the palmar aspect is used, allowing sensation and mobility while still protecting the hand. ...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/128.2.509

    authors: Nusbacher N,Pollak L,Bryk D

    更新日期:1978-08-01 00:00:00

  • Detection of simulated chest lesions by using soft-copy reading: comparison of an amorphous silicon flat-panel-detector system and a storage-phosphor system.

    abstract:PURPOSE:To compare observer performance by using soft-copy images produced by an amorphous silicon flat-panel-detector system and a storage-phosphor system for the detection of simulated chest lesions. MATERIALS AND METHODS:To test the diagnostic performance of these two systems, four types of simulated lesions (nodul...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.2241011441

    authors: Goo JM,Im JG,Lee HJ,Chung MJ,Seo JB,Kim HY,Lee YJ,Kang JW,Kim JH

    更新日期:2002-07-01 00:00:00

  • Single-session treatment of benign cystic thyroid nodules with ethanol versus radiofrequency ablation: a prospective randomized study.

    abstract:PURPOSE:To compare volume reduction of single-session ethanol ablation (EA) and radiofrequency (RF) ablation for cystic thyroid nodule treatment. MATERIALS AND METHODS:All patients gave written informed consent to participate in this prospective institutional review board-approved study. From May 6, 2010, to August 8,...

    journal_title:Radiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1148/radiol.13122134

    authors: Sung JY,Baek JH,Kim KS,Lee D,Yoo H,Kim JK,Park SH

    更新日期:2013-10-01 00:00:00

  • Congenital arteriovenous malformations: tailored embolotherapy.

    abstract::Congenital arteriovenous malformations (AVMs) involving the pelvis or an extremity were occluded in 16 symptomatic patients, who subsequently underwent tailored embolotherapy. An additional 11 patients did not undergo embolization due to unfavorable vascular anatomy or lack of significant symptoms. Permanent occlusive...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.169.2.3175000

    authors: Widlus DM,Murray RR,White RI Jr,Osterman FA Jr,Schreiber ER,Satre RW,Mitchell SE,Kaufman SL,Williams GM,Weiland AJ

    更新日期:1988-11-01 00:00:00

  • Nuclear magnetic resonance evaluation of stroke. A preliminary report.

    abstract::Nine patients who had acute and subacute stroke were examined by nuclear magnetic resonance (NMR) using a 6-MHz Bruker Instruments proton scanner. A modified Carr-Purcell-Meiboom-Gill pulse sequence was used for signal detection. The resultant string of spin-echoes was Fourier transformed into projections that were su...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.149.1.6310680

    authors: Bryan RN,Willcott MR,Schneiders NJ,Ford JJ,Derman HS

    更新日期:1983-10-01 00:00:00

  • Cirrhotic nodules: association between MR imaging signal intensity and intranodular blood supply.

    abstract:PURPOSE:To retrospectively determine whether there is a relationship between the intranodular blood supply evaluated at computed tomography (CT) during arterial portography (CTAP) and CT during hepatic arteriography (CTHA) and the magnetic resonance (MR) imaging signal intensity of nodules associated with cirrhosis. M...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.2372041389

    authors: Shinmura R,Matsui O,Kobayashi S,Terayama N,Sanada J,Ueda K,Gabata T,Kadoya M,Miyayama S

    更新日期:2005-11-01 00:00:00

  • Renal cell carcinoma: radiofrequency ablation with a multiple-electrode switching system--a phase II clinical study.

    abstract:PURPOSE:To prospectively evaluate the safety and effectiveness of radiofrequency ablation with a multiple-electrode switching system for the treatment of renal cell carcinoma (RCC). MATERIALS AND METHODS:From November 2009 to December 2010, 33 patients (mean age, 70.7 years; range, 44-86 years) with histologically pro...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.12121070

    authors: Takaki H,Nakatsuka A,Uraki J,Yamanaka T,Fujimori M,Hasegawa T,Arima K,Sugimura Y,Yamakado K

    更新日期:2013-04-01 00:00:00

  • Metastatic gastrinomas: localization with selective arterial injection of secretin.

    abstract:PURPOSE:To evaluate localization of hepatic metastases with the intraarterial secretin injection test in Zollinger-Ellison syndrome (ZES). MATERIALS AND METHODS:Results in 74 patients with ZES (aged 15-70 years) were retrospectively studied. All patients had undergone computed tomography (CT), magnetic resonance (MR) ...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.198.1.8539410

    authors: Gibril F,Doppman JL,Chang R,Weber HC,Termanini B,Jensen RT

    更新日期:1996-01-01 00:00:00

  • Hepatocellular carcinoma treated with percutaneous radio-frequency ablation: usefulness of power Doppler US with a microbubble contrast agent in evaluating therapeutic response-preliminary results.

    abstract:PURPOSE:To evaluate the usefulness of power Doppler ultrasonography (US) with a microbubble contrast agent in assessing the therapeutic response of hepatocellular carcinomas (HCCs) treated with percutaneous radio-frequency (RF) ablation. MATERIALS AND METHODS:Forty patients with 45 nodular HCC lesions 1.0-3.8 cm in di...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.217.2.r00oc07558

    authors: Choi D,Lim HK,Kim SH,Lee WJ,Jang HJ,Lee JY,Paik SW,Koh KC,Lee JH

    更新日期:2000-11-01 00:00:00

  • Hepatic malignancies: improved detection with pulse-inversion US in late phase of enhancement with SH U 508A-early experience.

    abstract::Twenty consecutive patients with known liver malignancies underwent ultrasonography (US) in conventional B mode and in pulse-inversion mode in the late hepatic-specific parenchymal phase after intravenous administration of SH U 508A, a microbubble US contrast agent. Two experienced readers assessed subjective and obje...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.216.3.r00se22903

    authors: Harvey CJ,Blomley MJ,Eckersley RJ,Cosgrove DO,Patel N,Heckemann RA,Butler-Barnes J

    更新日期:2000-09-01 00:00:00

  • Fibroid-related menorrhagia: treatment with superselective embolization of the uterine arteries and midterm follow-up.

    abstract:PURPOSE:To prospectively evaluate the effectiveness and safety of selective embolization of the uterine arteries in the management of symptomatic uterine leiomyoma. MATERIALS AND METHODS:Eighty consecutive women (mean age, 44.7 years) with symptomatic uterine leiomyoma, none of whom desired future pregnancy, underwent...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.215.2.r00ma11428

    authors: Pelage JP,Le Dref O,Soyer P,Kardache M,Dahan H,Abitbol M,Merland JJ,Ravina JH,Rymer R

    更新日期:2000-05-01 00:00:00

  • Isolated choroid plexus cysts in the second-trimester fetus: is amniocentesis really indicated?

    abstract::Choroid plexus (CP) cysts have been associated with trisomy 18, although most fetuses with CP cysts are normal. Since many fetuses with trisomy 18 have other sonographic abnormalities, the necessity of obtaining a karyotype for all fetuses with isolated CP cysts remains controversial. The authors prospectively studied...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.185.2.1410370

    authors: Nadel AS,Bromley BS,Frigoletto FD Jr,Estroff JA,Benacerraf BR

    更新日期:1992-11-01 00:00:00

  • Disease activity in osteomyelitis: role of radiography.

    abstract::To determine the impact of radiographic findings on the interpretation of bone and gallium scans of patients with active osteomyelitis, the authors reviewed the medical records and radiologic examinations of 104 patients. The only diagnostic finding of active disease on radiographs was the presence of a sequestrum (th...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.165.3.3685360

    authors: Tumeh SS,Aliabadi P,Weissman BN,McNeil BJ

    更新日期:1987-12-01 00:00:00

  • Noninvasive measurement of extraction fraction and single-kidney glomerular filtration rate with MR imaging in swine with surgically created renal arterial stenoses.

    abstract:PURPOSE:To test whether magnetic resonance (MR) imaging enables accurate measurement of extraction fraction (EF) in swine with unilateral renal ischemia and to evaluate effects of renal arterial stenosis on EF and single-kidney glomerular filtration rate. MATERIALS AND METHODS:High-grade unilateral renal arterial sten...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.2231010420

    authors: Coulam CH,Lee JH,Wedding KL,Spielman DM,Pelc NJ,Kee ST,Hill BB,Bouley DM,Derby GC,Myers BD,Sawyer-Glover AM,Sommer FG

    更新日期:2002-04-01 00:00:00

  • Percutaneous adrenal biopsy: review of a 10-year experience.

    abstract:PURPOSE:To evaluate the indications for and complications, accuracy, and techniques of percutaneous adrenal biopsy performed from 1982 through 1991 at the authors' institution. MATERIALS AND METHODS:Two hundred seventy-seven percutaneous adrenal biopsies were performed in 270 patients (175 male and 102 female patients...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.193.2.7972740

    authors: Welch TJ,Sheedy PF 2nd,Stephens DH,Johnson CM,Swensen SJ

    更新日期:1994-11-01 00:00:00

  • Chronic obstructive pulmonary disease: thin-section CT measurement of airway wall thickness and lung attenuation.

    abstract:PURPOSE:To prospectively evaluate airway wall thickness and lung attenuation at spirometrically gated thin-section computed tomography (CT) in patients with chronic obstructive pulmonary disease (COPD) and to correlate gated CT findings with pulmonary function test (PFT) results. MATERIALS AND METHODS:The ethical comm...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.2342040013

    authors: Orlandi I,Moroni C,Camiciottoli G,Bartolucci M,Pistolesi M,Villari N,Mascalchi M

    更新日期:2005-02-01 00:00:00

  • Gray-scale ultrasonography and endoscopic pancreatography in pancreatic diagnosis.

    abstract::Ultrasonography and endoscopic retrograde cholangiopancreatography (ERCP) were performed in 216 patients with known or suspected pancreatic disease. Both techniques provided accurate information in all groups of patients (normals and those with recurrent acute pancreatitis, chronic pancreatitis, and cancer), and there...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.134.2.7352230

    authors: Cotton PB,Lees WR,Vallon AG,Cottone M,Croker JR,Chapman M

    更新日期:1980-02-01 00:00:00

  • Urinary tract after abdomino-perineal resection.

    abstract::Uroradiological examinations on 33 patients subjected to abdomino-perineal resection were analyzed. The most common finding was medial displacement of both ureters, with the right one frequently crossing the midline. Bladder deformity, sometimes severe, was present in all patients. Localized ureteral narrowing due to ...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/128.2.345

    authors: Barbaric ZL,Wolfe DE,Segal AJ

    更新日期:1978-08-01 00:00:00

  • Common bile duct calculi: updated experience with dissolution with methyl tertiary butyl ether.

    abstract::The authors describe their experience with methyl tertiary butyl ether (MTBE) in a larger series of patients than previously reported in order to acquaint physicians with both its effectiveness for dissolution of common bile duct calculi and the limitations of its use. Ten patients with 13 biliary calculi underwent pe...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.166.3.3340760

    authors: Brandon JC,Teplick SK,Haskin PH,Sammon JK,Muhr WF,Hofmann AF,Gambescia RA,Zitomer N

    更新日期:1988-03-01 00:00:00

  • Relevance of spinal cord abnormalities to clinical disability in multiple sclerosis: MR imaging findings in a large cohort of patients.

    abstract:PURPOSE:To determine whether spinal cord atrophy differs among disease subtypes in multiple sclerosis (MS) and whether it offers diagnostic and clinical correlative information beyond that provided by other magnetic resonance (MR) imaging markers. MATERIALS AND METHODS:The institutional review board approved the study...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.13122566

    authors: Lukas C,Sombekke MH,Bellenberg B,Hahn HK,Popescu V,Bendfeldt K,Radue EW,Gass A,Borgwardt SJ,Kappos L,Naegelin Y,Knol DL,Polman CH,Geurts JJ,Barkhof F,Vrenken H

    更新日期:2013-11-01 00:00:00

  • A comparison of the effects of 50 MeVd leads to be neutron and cobalt-60 irradiation of the kidneys of rhesus monkeys.

    abstract::Twenty rhesus monkeys had one kidney irradiated (after undergoing unilateral nephrectomies) with one of four doses: 960 or 1080 rads of 50 MeVd leads to Be neutrons, or 2350 or 2700 rads of 60Co. Whereas animals treated with the lower dose of neutrons or 60Co are alive with relatively normal renal function, those trea...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/128.1.245

    authors: Raulston GL,Gray KN,Gleiser CA,Jardine JH,Flow BL,Huchton JI,Bennett KR,Hussey DH

    更新日期:1978-07-01 00:00:00

  • Artifacts in iodine-131 renal images due to coincidence summing of technetium-99m photons.

    abstract::Technetium-99m gamma camera images of kidneys produced with an iodine-131 energy window showed "ghosts" over and between the kidneys and between the kidneys and the bladder. The cause was coincidence summing at 281 keV due to a high 99mTc counting rate. In older model cameras careful peaking with a proper energy windo...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.146.2.6849100

    authors: Harris CC,Wilkinson RH Jr,Schuler FR

    更新日期:1983-02-01 00:00:00