Metabolism and detoxification of TNT by Phanerochaete chrysosporium.

abstract：:This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. ...

journal_title：Biochemical and biophysical research communications

authors： Xiao F,Hu Q,Zeng M,Guan L,Liu X,Yang Y,Zhong C

更新日期：2012-04-13 00:00:00

abstract：:This investigation is aimed to determine whether the biosynthesis of H(2)S, an endogenous vasodilator gas, is altered in the streptozotocin-diabetic rat. Plasma H(2)S concentration as well as the activity, and expression, of H(2)S synthesizing enzymes (namely cystathionine-gamma-lyase (CSE) and cystathionine-beta-synt...

journal_title：Biochemical and biophysical research communications

authors： Yusuf M,Kwong Huat BT,Hsu A,Whiteman M,Bhatia M,Moore PK

更新日期：2005-08-12 00:00:00

abstract：:To further define the molecular interaction between decorin and type I collagen we generated a 20 kD fragment containing the N-terminal half of the core protein by Endoproteinase Arg C digestion and a 40 kD fragment including all leucine-rich repeats in the central part of decorin core by cleavage with 2-nitro-5-thioc...

journal_title：Biochemical and biophysical research communications

authors： Pogány G,Vogel KG

更新日期：1992-11-30 00:00:00

abstract：:The 3(')-->5(')-exonucleolytic activity of human apurinic/apyrimidinic endonuclease 1 (APE1) on mispaired DNA at the 3(')-termini of recessed, nicked or gapped DNA molecules was analyzed and compared with the primary endonucleolytic activity. We found that under reaction conditions optimal for AP endonuclease activity...

journal_title：Biochemical and biophysical research communications

authors： Lebedeva NA,Khodyreva SN,Favre A,Lavrik OI

更新日期：2003-01-03 00:00:00

abstract：:As vectors, adenoviruses (Ads) have many attractive advantages for in vivo gene therapy. However, Ads do not usually integrate into the host genome and gene expression is, thus, transient. Adeno-associated virus (AAV) integrates into a specific locus (AAVS1) on the human host's chromosome 19, while conventional recomb...

journal_title：Biochemical and biophysical research communications

authors： Ueno T,Matsumura H,Tanaka K,Iwasaki T,Ueno M,Fujinaga K,Asada K,Kato I

更新日期：2000-07-05 00:00:00

abstract：:Leukocyte recruitment to lymph nodes or inflammatory sites is regulated by adhesion and activation. L-selectin (CD62L) is expressed on leukocytes and mediates tethering and rolling of leukocytes on endothelial cells. Upon stimulation L-selectin is down-regulated by proteolytic cleavage but the molecular mechanisms reg...

journal_title：Biochemical and biophysical research communications

authors： Phong MC,Gutwein P,Kadel S,Hexel K,Altevogt P,Linderkamp O,Brenner B

更新日期：2003-01-10 00:00:00

abstract：:Gelsolin, a Ca(2+)-dependent actin regulatory protein, was recently suggested to participate in apoptosis regulation. In this study, we found that the level of gelsolin is elevated in senescent human diploid fibroblasts (HDFs) and also in the tissues of old rats, i.e., in the liver, kidney, heart, spleen, stomach, and...

journal_title：Biochemical and biophysical research communications

authors： Ahn JS,Jang IS,Kim DI,Cho KA,Park YH,Kim K,Kwak CS,Chul Park S

更新日期：2003-12-26 00:00:00

abstract：:Although proteins are generally composed of l-alpha-amino acids, biologically uncommon D-beta-aspartic acid (Asp)-containing proteins have been reported in various tissues from elderly individuals. Our previous study indicated that the N/N1003A cell line, derived from rabbit lens, includes D-beta-Asp-containing protei...

journal_title：Biochemical and biophysical research communications

authors： Takata T,Shimo-Oka T,Miki K,Fujii N

更新日期：2005-09-09 00:00:00

abstract：:The heterodimeric F-actin capping protein cap32/34 from Dictyostelium discoideum is a typical member of a widely distributed family of cytoskeletal proteins. To analyze its regulation and structure/function relationships we cloned and expressed the subunits separately in Escherichia coli using the ATG-expression vecto...

journal_title：Biochemical and biophysical research communications

authors： Haus U,Hartmann H,Trommler P,Noegel AA,Schleicher M

更新日期：1991-12-16 00:00:00

abstract：:Multidrug resistance (MDR) in mammalian tumors or tissues is often associated with the overexpression of the putative drug efflux pump P-glycoprotein (Pgp). One theory concerning the mechanism of Pgp activity is that efflux of ATP is coupled to drug efflux. Evidence in support of this theory has been observed in mamma...

journal_title：Biochemical and biophysical research communications

authors： Boyum R,Guidotti G

更新日期：1997-01-03 00:00:00

abstract：:The presence of at least two distinct Mg2+- or Mn2+-dependent, Ca2+-independent endonuclease activities was shown in the myeloid leukemia cell line P39. One of them was recovered from nuclear extracts and the other from a cytoplasmic fraction. The molecular size of the former was 30 kDa in both gel filtration and acti...

journal_title：Biochemical and biophysical research communications

authors： Kawabata H,Anzai N,Masutani H,Hirama T,Hishita T,Dodo M,Masuda T,Yoshida Y,Okuma M

更新日期：1997-04-07 00:00:00

abstract：:Human MCF7 breast tumor cells grew as estrogen-dependent tumors in nude mice. In contrast, they were not estrogen-dependent for proliferation in serumless culture media. Charcoal-dextran stripped female human serum supplemented media (5% to 40%) inhibited their proliferation in a dose dependent pattern. Estrogens reve...

journal_title：Biochemical and biophysical research communications

authors： Soto AM,Sonnenschein C

更新日期：1984-08-16 00:00:00

abstract：:We have previously shown that cationic cholesterol derivatives bearing guanidinium groups were efficient vectors for gene transfer. To further evaluate the potentiality of this novel class of cationic lipids, we undertook to study the transfection efficiency of guanidinium-based lipids with other hydrophobic moieties....

journal_title：Biochemical and biophysical research communications

authors： Patel M,Vivien E,Hauchecorne M,Oudrhiri N,Ramasawmy R,Vigneron JP,Lehn P,Lehn JM

更新日期：2001-02-23 00:00:00

abstract：:Parathyroid hormone (PTH) has a central role in the regulation of serum calcium and phosphate, while parathyroid hormone-related peptide (PTHrP) has important developmental roles. Both peptides signal through the same receptor, the PTH/PTHrP receptor (a class B G-protein-coupled receptor). The different biological eff...

journal_title：Biochemical and biophysical research communications

authors： Gensure RC,Gardella TJ,Jüppner H

更新日期：2005-03-18 00:00:00

abstract：:Transforming growth factor-beta (TGF-beta) is a cytokine important in inducing epithelial-mesenchymal transition (EMT), a crucial morphological event in a wide range of physiological and pathological cellular processes. In this study, we demonstrate that TGF-beta1 induces the EMT phenotype through decreasing the expre...

journal_title：Biochemical and biophysical research communications

authors： Lee EK,Jeon WK,Chae MY,Hong HY,Lee YS,Kim JH,Kwon JY,Kim BC,Park SH

更新日期：2010-01-01 00:00:00

abstract：:Polyribosomes were isolated without the use of detergents, irradiated with ultraviolet light and labelled in the presence of (gamma-32P) adenosine 5'-triphosphate. Poly(A)+RNA-protein structures separated by chromatography on oligo (dT)-cellulose contained up to 1o crosslinked proteins as shown by SDS-polyacrylamide g...

journal_title：Biochemical and biophysical research communications

authors： Schweiger A,Kostka G,Weiss E

更新日期：1986-04-14 00:00:00

abstract：:Treatment of the isolated nuclei with polyanions (PA) (heparin and dextran-sulfate) at the PA/DNA ratio of about 1 in the 0.15-0.5 M ammonium acetate solution leads to rearrangement of the chromatin structure and formation of compact globular particles (GP) 40-70 nm in diameter, bound by fibrils of variable thickness ...

journal_title：Biochemical and biophysical research communications

authors： Prusov AN,Fais D,Polyakov VYu

更新日期：1993-06-15 00:00:00

abstract：:Polyclonal antibodies have been obtained against a synthetic dodecapeptide identical to the aminoacid sequence 120-131 DSPIKDGVWPPE (inferred from its DNA sequence) of Paracoccus denitrificans cytochrome c oxidase subunit III. The antibodies had a titer higher than 1:10000 when tested against the antigen. These antibo...

journal_title：Biochemical and biophysical research communications

authors： Müller M,Labonia N,Azzi A

更新日期：1988-08-15 00:00:00

abstract：:We previously reported that moderate hypoxia and hypoxia-mimetic agents including cobalt chloride (CoCl(2)) induce differentiation of human acute myeloid leukemia (AML) cells through hypoxia-inducible factor-1 α (HIF-1 α), which interacts with and enhances transcriptional activity of CCAAT-enhancer binding factor alph...

journal_title：Biochemical and biophysical research communications

authors： Yan ZW,Hou JK,He W,Fan L,Huang Y

更新日期：2013-01-18 00:00:00

abstract：:Distribution of mRNA expression of 1,25-dihydroxyvitamin D3 receptor (VDR) and 25-hydroxyvitamin D3-24-hydroxylase (24-OHase) along the microdissected rat nephron segments was examined by reverse transcription-polymerase chain reaction (RT-PCR) technique. VDR mRNA was abundantly expressed in cortical segments (glomeru...

journal_title：Biochemical and biophysical research communications

authors： Iida K,Taniguchi S,Kurokawa K

更新日期：1993-07-30 00:00:00

abstract：:Using a novel method consisting of chromatin fractionation and allele-specific detection, chromatin packaging is compared between active X (Xa) and inactive X (Xi) chromosomes for five tumor cell clones that were derived from inter-subspecific F1 female mice. Separation of heterochromatic (H) and euchromatic (E) fract...

journal_title：Biochemical and biophysical research communications

authors： Endo Y,Watanabe T,Kuwabara K,Tsunashima K,Mishima Y,Arakawa M,Takagi N,Kominami R

更新日期：1998-03-06 00:00:00

abstract：:Endochondral ossification is a crucial process for longitudinal growth of bones. Differentiating chondrocytes in growth cartilage form four sequential zones of proliferation, alignment into column, hypertrophy, and substitution of chondrocytes with osteoblasts. Wnt/β-catenin signaling is essential for differentiation ...

journal_title：Biochemical and biophysical research communications

authors： Takegami Y,Ohkawara B,Ito M,Masuda A,Nakashima H,Ishiguro N,Ohno K

更新日期：2016-04-22 00:00:00

abstract：:Previous studies have demonstrated expression of Toll-like receptors (TLRs) in the surface epithelium of normal ovaries (OSE) and in epithelial ovarian tumors. Most notably, OSE-derived cancers express TLR4, which activates the nuclear factor-kappa B (NF-κB) signaling cascade as a mediator of inflammatory response. Cu...

journal_title：Biochemical and biophysical research communications

authors： Woods DC,White YA,Dau C,Johnson AL

更新日期：2011-06-17 00:00:00

abstract：:We previously reported transplantation of brain microvascular endothelial cells (MVECs) into cerebral white matter infarction model improved the animal's behavioral outcome by increasing the number of oligodendrocyte precursor cells (OPCs). We also revealed extracellular vesicles (EVs) derived from MVECs promoted surv...

journal_title：Biochemical and biophysical research communications

authors： Osawa S,Kurachi M,Yamamoto H,Yoshimoto Y,Ishizaki Y

更新日期：2017-06-17 00:00:00

abstract：:Mizoribine (MIZ) is a novel imidazole nucleoside with immunosuppressive activity. MIZ has been approved in Japan and combination therapy with MIZ and glucocorticoids has been used after renal transplantation and for lupus nephritis and rheumatoid arthritis. In this study, we identify 14-3-3 proteins as MIZ-binding pro...

journal_title：Biochemical and biophysical research communications

authors： Takahashi S,Wakui H,Gustafsson JA,Zilliacus J,Itoh H

更新日期：2000-07-21 00:00:00

abstract：:Nuclei were isolated from bloodstream forms of Trypanosoma brucei by nitrogen cavitation and sedimentation through percoll density gradients. Transcription studies with these nuclei in vitro demonstrated features not seen with other eukaryotes: RNA synthesis was much greater in the presence of Mn2+ than with Mg2+ and ...

journal_title：Biochemical and biophysical research communications

authors： Earnshaw DL,Beebee TJ,Gutteridge WE

更新日期：1985-09-16 00:00:00

abstract：:To examine the possibility that the Orf135 protein of Escherichia coli functions as a hydrolyzing enzyme for a damaged DNA precursor (deoxyribonucleoside 5'-triphosphate), we purified the recombinant Orf135 protein and incubated it with oxidized deoxynucleotides. Of the nucleotides tested, 2-hydroxydeoxyadenosine 5'-t...

journal_title：Biochemical and biophysical research communications

authors： Kamiya H,Murata-Kamiya N,Iida E,Harashima H

更新日期：2001-11-02 00:00:00

abstract：:In a 28-year-old man with myopathy and phosphorylase kinase (PhK) deficiency, we found a G-to-C substitution at the 5' end of an intron in the muscle-specific alpha-subunit gene. The mutation destroys the high-consensus GT sequences at the 5' splice junction of the intron, which causes skipping of the preceding exon. ...

journal_title：Biochemical and biophysical research communications

authors： Bruno C,Manfredi G,Andreu AL,Shanske S,Krishna S,Ilse WK,DiMauro S

更新日期：1998-08-28 00:00:00

abstract：:Adenovirus DNA synthesis carried out in vitro was inhibited by the aphidicolin. However, 30% of the DNA synthesis was resistant to aphidicolin even at a concentration of 200 micrograms/ml. When the distribution patterns of the radioactivity of the products synthesized in the presence of 50 micrograms/ml of the drug wa...

journal_title：Biochemical and biophysical research communications

authors： Ariga H

更新日期：1983-05-31 00:00:00

abstract：:Fusarium graminearum produces trichothecenes in aerial hyphae, a process which is markedly suppressed by NaCl without a significant effect on fungal growth. Here we report on the involvement of kinases of the two-component osmotic signal transduction pathway in the regulation of secondary metabolism in F. graminearum....

journal_title：Biochemical and biophysical research communications

authors： Ochiai N,Tokai T,Nishiuchi T,Takahashi-Ando N,Fujimura M,Kimura M

更新日期：2007-11-23 00:00:00