Modification of the noradrenaline related effects of smoking by beta-blockade.

Abstract:

:Increases in plasma noradrenaline were found in a group of 12 subjects smoking cigarettes. The associated rises in pulse rate, blood pressure and plasma free fatty acids could be prevented by beta-blockade with oxprenolol. This inhibition of the peripheral effects of catecholamines did not affect subjective satisfaction, indicating that central effects or other rewards are more important reinforcers. It is suggested that noradrenaline release in the hypothalamus is the final common pathway to pleasure in many situations, including smoking.

journal_name

Psychol Med

journal_title

Psychological medicine

authors

Carruthers M

doi

10.1017/s0033291700013799

subject

Has Abstract

pub_date

1976-05-01 00:00:00

pages

251-6

issue

2

eissn

0033-2917

issn

1469-8978

journal_volume

6

pub_type

临床试验,杂志文章
  • Suicide in recently released prisoners: a case-control study.

    abstract:BACKGROUND:Recently released prisoners are at markedly higher risk of suicide than the general population. The aim of this study was to identify key risk factors for suicide by offenders released from prisons in England and Wales. METHOD:All suicides committed by offenders within 12 months of their release from prison...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291709991048

    authors: Pratt D,Appleby L,Piper M,Webb R,Shaw J

    更新日期:2010-05-01 00:00:00

  • Developmental influences on symptom expression in antipsychotic-naïve first-episode psychosis.

    abstract:BACKGROUND:The neurodevelopmental model of psychosis was established over 30 years ago; however, the developmental influence on psychotic symptom expression - how age affects clinical presentation in first-episode psychosis - has not been thoroughly investigated. METHODS:Using generalized additive modeling, which allo...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291720003463

    authors: Bridgwater M,Bachman P,Tervo-Clemmens B,Haas G,Hayes R,Luna B,Salisbury DF,Jalbrzikowski M

    更新日期:2020-10-06 00:00:00

  • The views and outcomes of consenting and non-consenting patients receiving ECT.

    abstract:BACKGROUND:Current mental health legislation in the UK makes provision for the use of certain treatments in severely ill patients who are unable, or unwilling, to give informed consent. Under the terms of this legislation, electroconvulsive therapy (ECT) may be used, usually to treat severely depressed patients. A numb...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291798007193

    authors: Wheeldon TJ,Robertson C,Eagles JM,Reid IC

    更新日期:1999-01-01 00:00:00

  • Assessing risk of neurodevelopmental disorders after birth with oxytocin: a systematic review and meta-analysis.

    abstract::Experts have raised concerns that oxytocin for labor induction and augmentation may have detrimental effects on the neurodevelopment of children. To investigate whether there is the reason for concern, we reviewed and evaluated the available evidence by searching databases with no language or date restrictions up to 9...

    journal_title:Psychological medicine

    pub_type: 杂志文章,meta分析

    doi:10.1017/S0033291718003021

    authors: Lønfeldt NN,Verhulst FC,Strandberg-Larsen K,Plessen KJ,Lebowitz ER

    更新日期:2019-04-01 00:00:00

  • Trajectories of childhood neighbourhood cohesion and adolescent mental health: evidence from a national Canadian cohort.

    abstract:BACKGROUND:The objective of this study was to examine associations between trajectories of childhood neighbourhood social cohesion and adolescent mental health and behaviour. METHOD:This study used data from the National Longitudinal Survey of Children and Youth, a nationally representative sample of Canadian children...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291715001245

    authors: Kingsbury M,Kirkbride JB,McMartin SE,Wickham ME,Weeks M,Colman I

    更新日期:2015-11-01 00:00:00

  • An analysis of suicide and undetermined deaths in 17 predominantly Islamic countries contrasted with the UK.

    abstract:BACKGROUND:Suicide is expressly condemned in the Qu'ran, and traditionally few Islamic countries have reported suicide. Undetermined deaths are classified by the World Health Organization (WHO) as Other Violent Deaths (OVD) in ICD-9, or Other External Causes (OEC) in ICD-10. It has been suggested that to avoid under-re...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291706009159

    authors: Pritchard C,Amanullah S

    更新日期:2007-03-01 00:00:00

  • COMT Val158Met moderation of stress-induced psychosis.

    abstract:BACKGROUND:Exposure to stressful life events increases the risk of developing a psychotic disorder. Moreover, increased reactivity to stress seems to represent part of the vulnerability for psychosis. This study aimed to investigate whether a functional polymorphism in the catechol-O-methyltransferase (COMT Val(158)Met...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291707001080

    authors: Stefanis NC,Henquet C,Avramopoulos D,Smyrnis N,Evdokimidis I,Myin-Germeys I,Stefanis CN,Van Os J

    更新日期:2007-11-01 00:00:00

  • Epidemiology of mental disorders in Camberwell.

    abstract::A two-stage psychiatric survey of a random samples of adults aged 18-64 from Camberwell is described. Agency interviewers carried out the first stage (N = 800), using the shorter form of the Present State Examination (PSE). MRC interviewers, using the full PSE, saw a stratified sample of these (N = 310) in the second ...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700052879

    authors: Bebbington P,Hurry J,Tennant C,Sturt E,Wing JK

    更新日期:1981-08-01 00:00:00

  • Sleep disturbance mediates the link between childhood trauma and clinical outcome in severe mental disorders.

    abstract:BACKGROUND:The experience of childhood trauma is linked to more severe symptoms and poorer functioning in severe mental disorders; however, the mechanisms behind this are poorly understood. We investigate the relationship between childhood trauma and sleep disturbances in severe mental disorders including the role of s...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291720000914

    authors: Laskemoen JF,Aas M,Vaskinn A,Berg AO,Lunding SH,Barrett EA,Melle I,Simonsen C

    更新日期:2020-04-23 00:00:00

  • Psychometric assessment of psychiatric disorders in people with learning difficulties (mental handicap): a review of measures.

    abstract::Instruments designed to assess psychiatric disorders in people with learning difficulties (mental handicap) were critically reviewed from a psychometric perspective. Major trends were found in the assessment of psychopathology related to DSM-III and depressive disorders although research in other areas was patchy. Alt...

    journal_title:Psychological medicine

    pub_type: 杂志文章,评审

    doi:10.1017/s0033291700014732

    authors: Sturmey P,Reed J,Corbett J

    更新日期:1991-02-01 00:00:00

  • Optical coherence tomography indices of structural retinal pathology in schizophrenia.

    abstract:BACKGROUND:Prior optical coherence tomography (OCT) studies of schizophrenia have identified thinning of retinal layers. However, findings have varied across reports, and most studies have had serious methodological limitations. To address unresolved issues, we determined whether: (1) retinal thinning in schizophrenia ...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291717003555

    authors: Silverstein SM,Paterno D,Cherneski L,Green S

    更新日期:2018-09-01 00:00:00

  • Using age difference and sex similarity to detect evidence of sibling influence on criminal offending.

    abstract:BACKGROUND:Sibling resemblance in crime may be due to genetic relatedness, shared environment, and/or the interpersonal influence of siblings on each other. This latter process can be understood as a type of 'peer effect' in that it is based on social learning between individuals occupying the same status in the social...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291720003724

    authors: Mikkonen J,Savolainen J,Aaltonen M,Martikainen P

    更新日期:2020-10-21 00:00:00

  • Effect of propranolol and phenothiazines on electrodermal orienting and habituation in schizophrenia.

    abstract::Bilateral electrodermal orienting responses were measured to repeated auditory stimuli in schizophrenic patients and controls. In 3 studies phasic activity to moderate intensity sounds of patients on no drugs or phenothiazines was predominantly hyper- or hypo-responsive. Controls showed moderate or slow habituation. P...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700053319

    authors: Gruzelier J,Connolly J,Eves F,Hirsch S,Zaki S,Weller M,Yorkston N

    更新日期:1981-02-01 00:00:00

  • Suicide in England and Wales: an analysis of 100 years, 1876-1975.

    abstract::The variations in suicide mortality in England and Wales over a 100-year period (1876-1975) are explained by the development of a descriptive model. The model used in a stepwise linear regression using 5 variables including toxic gas production. The variables give a good description of the observed changes in suicide ...

    journal_title:Psychological medicine

    pub_type: 历史文章,杂志文章

    doi:10.1017/s003329170005217x

    authors: Low AA,Farmer RD,Jones DR,Rohde JR

    更新日期:1981-05-01 00:00:00

  • Group transdiagnostic cognitive-behavior therapy for anxiety disorders: a pragmatic randomized clinical trial.

    abstract:BACKGROUND:Transdiagnostic group cognitive-behavioral therapy (tCBT) is a delivery model that could help overcome barriers to large-scale implementation of evidence-based psychotherapy for anxiety disorders. The aim of this study was to assess the effectiveness of combining group tCBT with treatment-as-usual (TAU), com...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291720004316

    authors: Roberge P,Provencher MD,Gaboury I,Gosselin P,Vasiliadis HM,Benoît A,Carrier N,Antony MM,Chaillet N,Houle J,Hudon C,Norton PJ

    更新日期:2020-12-02 00:00:00

  • Antidepressant use and work-related injuries.

    abstract:BACKGROUND:Adverse effects of antidepressants are most common at the beginning of the treatment, but possible also later. We examined the association between antidepressant use and work-related injuries taking into account the duration of antidepressant use. METHOD:Antidepressant use and work-related injuries between ...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291715002925

    authors: Kouvonen A,Vahtera J,Pentti J,Korhonen MJ,Oksanen T,Salo P,Virtanen M,Kivimäki M

    更新日期:2016-05-01 00:00:00

  • Physical activity and prevalence and incidence of mental disorders in adolescents and young adults.

    abstract:BACKGROUND:Although positive effects of physical activity on mental health indicators have been reported, the relationship between physical activity and the development of specific mental disorders is unclear. METHOD:A cross-sectional (12-month) and prospective-longitudinal epidemiological study over 4 years in a comm...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S003329170700089X

    authors: Ströhle A,Höfler M,Pfister H,Müller AG,Hoyer J,Wittchen HU,Lieb R

    更新日期:2007-11-01 00:00:00

  • Cognitive impairment in the euthymic phase of affective disorder.

    abstract:BACKGROUND:A review of studies of cognition in the euthymic phase of unipolar and bipolar affective disorder reveals diverging results. METHODS:The study was designed as a controlled cohort study, with the Danish psychiatric case register of admissions used to identify patients and the Danish civil register to identif...

    journal_title:Psychological medicine

    pub_type: 临床试验,杂志文章

    doi:10.1017/s0033291798006862

    authors: Kessing LV

    更新日期:1998-09-01 00:00:00

  • Internet-based cognitive behavioural therapy for subthreshold depression in people over 50 years old: a randomized controlled clinical trial.

    abstract:BACKGROUND:Subthreshold depression is a highly prevalent condition and a risk factor for developing a major depressive episode. Internet-based cognitive behaviour therapy may be a promising approach for the treatment of subthreshold depression. The current study had two aims: (1) to determine whether an internet-based ...

    journal_title:Psychological medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1017/S0033291707000542

    authors: Spek V,Nyklícek I,Smits N,Cuijpers P,Riper H,Keyzer J,Pop V

    更新日期:2007-12-01 00:00:00

  • The neuropsychology of prefrontal function in antisocial personality disordered offenders with varying degrees of psychopathy.

    abstract:BACKGROUND:Despite methodological differences between studies, it has been suggested that psychopathy may be associated with a ventromedial prefrontal cortex (VMPFC) deficit and antisocial personality disorder (ASPD), as classified in the DSM-IV, with a broader range of deficits in dorsolateral prefrontal cortex (DLPFC...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291711002686

    authors: Dolan M

    更新日期:2012-08-01 00:00:00

  • Undue influence of weight and shape: is it distinct from body dissatisfaction and concern about weight and shape?

    abstract:BACKGROUND:Three cognitive constructs are risk factors for eating disorders: undue influence of weight and shape, concern about weight and shape, and body dissatisfaction (BD). Undue influence, a diagnostic criterion for eating disorders, is postulated to be closely associated with self-esteem whereas BD is postulated ...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291710001066

    authors: Wade TD,Zhu G,Martin NG

    更新日期:2011-04-01 00:00:00

  • Do socio-economic risk factors predict the incidence and maintenance of psychiatric disorder in primary care?

    abstract::In a prospective cohort study of consecutive primary care attenders in south London, the estimated prevalence of non-psychotic psychiatric disorder was 45.6%, using the Revised Clinical Interview Schedule (CIS-R). The estimated 12-month incidence rate was 15.7%. Extremely high stability was found in CIS-R scores over ...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291796004023

    authors: Weich S,Churchill R,Lewis G,Mann A

    更新日期:1997-01-01 00:00:00

  • Lymphocyte numbers in endogenous depression.

    abstract::The blood counts of 80 patients with depression were examined (50 unipolar, 30 bipolar). Many had reduced numbers of circulating lymphocytes. This abnormality was more common in the unipolar group (52%) than in the bipolar group (27%). When those patients with an abnormal dexamethasone suppression test response in bot...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700024934

    authors: Murphy D,Gardner R,Greden JF,Carroll BJ

    更新日期:1987-05-01 00:00:00

  • The causal nature of the association between resting pulse in late adolescence and risk for internalizing and externalizing disorders: a co-relative analysis in a national male Swedish sample.

    abstract:BACKGROUND:Resting pulse is robustly and inversely associated with the risk for externalizing disorders and may be positively associated with internalizing disorders. We know little about the causal nature of these associations. METHODS:We examined resting pulse at conscription examination in 369 301 males born 1960-8...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291720000549

    authors: Kendler KS,Lönn SL,Sundquist J,Sundquist K

    更新日期:2020-03-24 00:00:00

  • Bulimia nervosa: a four- to six-year follow-up study.

    abstract::A consecutive series of 45 female bulimic patients treated by one of us was followed four to six years after termination of treatment. Thirty-five (78%) were successfully followed, six refused to participate in the study and four were untraced. At least seven (16%) had diagnosable bulimia nervosa at follow-up, and at ...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700005766

    authors: Hsu LK,Sobkiewicz TA

    更新日期:1989-11-01 00:00:00

  • A computerized psychiatric diagnostic system and case nomenclature for elderly subjects: GMS and AGECAT.

    abstract::The Geriatric Mental State and a new computerized diagnostic system, AGECAT, are briefly described. A nomenclature for designating cases for epidemiological work is introduced. Concordance between AGECAT and psychiatrists' diagnoses for these studies, hospital and community based (total of 541 subjects), achieved over...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700057779

    authors: Copeland JR,Dewey ME,Griffiths-Jones HM

    更新日期:1986-02-01 00:00:00

  • Tobacco smoking is associated with psychotic experiences in the general population of South London.

    abstract:BACKGROUND:The association between cigarette smoking and psychosis remains unexplained, but could relate to causal effects in both directions, confounding by socioeconomic factors, such as ethnicity, or use of other substances, including cannabis. Few studies have evaluated the association between cigarettes and psycho...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291717001556

    authors: Bhavsar V,Jauhar S,Murray RM,Hotopf M,Hatch SL,McNeill A,Boydell J,MacCabe JH

    更新日期:2018-01-01 00:00:00

  • Risk markers for both chronic fatigue and irritable bowel syndromes: a prospective case-control study in primary care.

    abstract:BACKGROUND:Fatigue syndromes and irritable bowel syndrome (IBS) often occur together. Explanations include being different manifestations of the same condition and simply sharing some symptoms. METHOD:A matched case-control study in UK primary care, using data collected prospectively in the General Practice Research D...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291709005601

    authors: Hamilton WT,Gallagher AM,Thomas JM,White PD

    更新日期:2009-11-01 00:00:00

  • Bullying victimization in youths and mental health problems: 'much ado about nothing'?

    abstract::Bullying victimization is a topic of concern for youths, parents, school staff and mental health practitioners. Children and adolescents who are victimized by bullies show signs of distress and adjustment problems. However, it is not clear whether bullying is the source of these difficulties. This paper reviews empiri...

    journal_title:Psychological medicine

    pub_type: 杂志文章,评审

    doi:10.1017/S0033291709991383

    authors: Arseneault L,Bowes L,Shakoor S

    更新日期:2010-05-01 00:00:00

  • Dimensions of irritability in adolescents: longitudinal associations with psychopathology in adulthood.

    abstract:BACKGROUND:There is an emerging consensus in developmental psychopathology that irritable youth are at risk for developing internalizing problems later in life. The current study explored if irritability in youth is multifactorial and the impact of irritability dimensions on psychopathology outcomes in adulthood. METH...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291719002903

    authors: Hawes MT,Carlson GA,Finsaas MC,Olino TM,Seely JR,Klein DN

    更新日期:2020-12-01 00:00:00