Abstract:
OBJECTIVES:To provide an overview of the clinical development of ZD1839 and other epidermal growth factor receptor (EGFR) inhibitors in the treatment of advanced non-small cell lung cancer (NSCLC). DATA SOURCES:Research articles and abstracts. CONCLUSIONS:Increased understanding of cancer biology has led to the development of multiple targeted agents to evaluate clinically in the treatment of various cancers. The EGFR inhibitors appear promising in the treatment of NSCLC. ZD1839 has shown activity and symptom and quality-of-life improvements in two large phase II trials. Ongoing and future trials will continue to explore the optimal use of ZD1839 and other EGFR inhibitors in the treatment of NSCLC. IMPLICATIONS FOR NURSING PRACTICE:Several investigational EGFR inhibitors are likely to become commercially available over the next few years. Nurses should be knowledgeable regarding these agents to provide appropriate patient and family education and to assure safe drug delivery.
journal_name
Semin Oncol Nursjournal_title
Seminars in oncology nursingauthors
Thomas Mdoi
10.1053/sonu.2002.37408subject
Has Abstractpub_date
2002-11-01 00:00:00pages
20-7issue
4 Suppl 4eissn
0749-2081issn
1878-3449pii
S0749-2081(02)80083-3journal_volume
18pub_type
杂志文章,评审abstract:OBJECTIVES:To review the epidemiology and prevention of teen smoking and the risks of smoking among survivors of childhood cancer. DATA SOURCES:Research articles, government reports, and surveys. CONCLUSION:Nicotine dependence often begins with the first few cigarettes smoked during adolescence. Teen tobacco use is f...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1053/j.soncn.2003.08.003
更新日期:2003-11-01 00:00:00
abstract:OBJECTIVES:To review the development of advocacy and its influence on health policy from the perspective of AIDS, the American Cancer Society, the Cancer Leadership Council, and the Patient Advocacy Foundation. DATA SOURCES:Published articles, news articles, books and personal experience. CONCLUSIONS:Advocacy on beha...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章
doi:10.1053/sonu.2002.35937
更新日期:2002-11-01 00:00:00
abstract:OBJECTIVES:To provide assessment guidelines and management strategies for symptoms affecting nutritional status in patients with cancer. DATA SOURCES:Published articles, book chapters, and research reports. CONCLUSIONS:Patients with cancer experience a variety of symptoms that affect their nutritional status. It is p...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1053/on.2000.5738
更新日期:2000-05-01 00:00:00
abstract::Clinical trials have demonstrated that rIL-2 can be safely administered in an outpatient setting. A thorough nursing assessment ensures patient safety and effective toxicity management. Because it is becoming more economically advantageous to treat patients on an outpatient basis, nurses will need to become involved i...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章
doi:
更新日期:1993-08-01 00:00:00
abstract:OBJECTIVES:To discuss current long-term follow-up management, the need for a long-term database, and creative strategies for follow-up care for cancer survivors. DATA SOURCES:Published articles, position statements, and personal experience. CONCLUSIONS:As the number of long-term cancer survivors increases, there need...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章
doi:10.1053/sonu.2001.27921
更新日期:2001-11-01 00:00:00
abstract::Where and how can we best care for oncology patients, and what are the models of care that will provide safe patient and family-centered care while containing costs? Because the majority of all cancer care is delivered in the outpatient setting, the types of outpatient oncology settings, the services provided, and the...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/s0749-2081(05)80070-1
更新日期:1994-11-01 00:00:00
abstract::Establishing cancer patient education programs for hospitalized cancer patients may follow a six-stage process that includes planning and strategy selection, selecting channels and materials, developing materials and pretesting, implementation, assessing effectiveness, and obtaining feedback to refine the program. The...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章
doi:10.1016/0749-2081(91)90089-8
更新日期:1991-05-01 00:00:00
abstract:OBJECTIVES:To provide an overview on cancer patient education. DATA SOURCES:Literature related to demographic and health care trends, patient education, health literacy, and cancer patient information needs. CONCLUSIONS:Cancer patients need information related to diagnosis, treatment, side effects, self-care needs, a...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/s0749-2081(00)80007-8
更新日期:2000-02-01 00:00:00
abstract:OBJECTIVE:To review effective approaches for non-pain symptom management for cancer patients focusing on treatment of nausea and vomiting, constipation, diarrhea, anorexia/cachexia, fatigue, and dyspnea. DATA SOURCES:Peer-reviewed articles, clinical practice guidelines, professional organization position statements. ...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/j.soncn.2018.06.004
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVES:To provide an overview of the broad, multidimensional construct of sexuality addressing physiologic, psychological, and social dimensions. DATA SOURCES:Research articles, abstracts, standards of care, international reports. CONCLUSION:Multiple insults to the physiologic, psychological, and social dimension...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章
doi:10.1016/j.soncn.2008.02.001
更新日期:2008-05-01 00:00:00
abstract:OBJECTIVES:To provide an overview of relevant federal and state policies, as well as recommendations for identifying and addressing barriers to the treatment of cancer and non-cancer pain. DATA SOURCES:Review of federal and state statutes and medical board guidelines. CONCLUSIONS:There has been an increase in pain-re...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/s0749-2081(98)80022-3
更新日期:1998-05-01 00:00:00
abstract:OBJECTIVES:To discuss professional cancer navigation roles, models, implementation process and outcomes of patients and families dealing with head and neck cancers. One specific research is presented as an illustration. DATA SOURCES:Published scientific papers, research review articles, implementations studies. CONCL...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/j.soncn.2009.05.004
更新日期:2009-08-01 00:00:00
abstract::Individuals and families with hereditary cancers have informational needs that differ, depending on the availability of testing for increased hereditary risk and major focus of concern (reproductive decision-making or risk to self). Cancer risk counseling helps individuals understand risk information so they can make ...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章
doi:10.1016/0749-2081(92)90042-2
更新日期:1992-11-01 00:00:00
abstract::The many changes expected in the future will create challenges and opportunities in the field of patient education. The aging population, increased numbers of cancer survivors, minorities and disadvantaged patients, more illiteracy, and the changing health care system are a few of these trends. They will require broad...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章
doi:10.1016/0749-2081(91)90093-5
更新日期:1991-05-01 00:00:00
abstract:OBJECTIVES:To explore the role of the arts in spirituality and spiritual care and the importance of the arts and creativity in health care settings, particularly where individuals are confronting life-threatening illnesses. DATA SOURCES:Professional and lay journals/magazines, and personal experience with oncology and...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章
doi:10.1016/s0749-2081(97)80018-6
更新日期:1997-11-01 00:00:00
abstract:OBJECTIVES:To review nursing science history within the Gynecology Oncology Group (GOG); to discuss challenges of nursing science in the cooperative group (CG) using a current nurse-led protocol (GOG-0259) as an exemplar; and to propose recommendations to advance nursing science in the CG setting. DATA SOURCES:Indexed...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章
doi:10.1016/j.soncn.2013.12.008
更新日期:2014-02-01 00:00:00
abstract::Utilization of critical care interventions for cancer patients has increased because of new hopes for cure or long-term remission, increased ability to treat certain complications, and consumer demand. Cancer therapies are more aggressive causing increased organ toxicity, prolonged aplasia, and a variety of complicati...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/s0749-2081(05)80081-6
更新日期:1994-08-01 00:00:00
abstract:OBJECTIVE:To provide an overview of hereditary cancer susceptibility genes and associated cancer risks. DATA SOURCES:Peer reviewed published research studies and review articles. CONCLUSIONS:Identifying deleterious mutations in cancer susceptibility genes allows for clarification of cancer risk in individual family m...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/j.soncn.2010.11.004
更新日期:2011-02-01 00:00:00
abstract:OBJECTIVES:To discuss the role and challenges of the oncology nurse navigator working within a multidisciplinary team caring for patients with various types of cancers. DATA SOURCES:Published empirical research and critical analysis articles. CONCLUSION:The experienced oncology nurse in the role of navigator has the ...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/j.soncn.2013.02.005
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVES:To explore avenues for establishing or expanding interprofessional (IP) collaboration, to provide guidance on authoring IP oncology publications, and to highlight platforms for IP publishing. DATA SOURCES:Journal articles, organizational guidelines, panel reports, and personal experience. CONCLUSION:As hea...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/j.soncn.2018.09.010
更新日期:2018-11-01 00:00:00
abstract:OBJECTIVES:To summarize, in tabular form, the current literature and information available for skin cancer preventive behaviors and sun protection recommendations. DATA SOURCES:Peer-reviewed literature, web sites of professional and federal organizations. CONCLUSION:The link between skin cancer and ultra-violet radia...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章
doi:10.1016/j.soncn.2013.06.008
更新日期:2013-08-01 00:00:00
abstract:OBJECTIVE:To provide a review of the use of monoclonal antibodies (MAbs) for diagnosis and therapy, the obstacles affecting their usefulness, and nursing considerations unique to MAb-based treatments. DATA SOURCES:Research studies, review articles, and book chapters pertaining to MAbs in cancer diagnosis and therapy. ...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/s0749-2081(96)80007-6
更新日期:1996-05-01 00:00:00
abstract:OBJECTIVES:To examine patterns and trends in lung cancer and the risk factors associated with development of this disease. DATA SOURCES:Epidemiologic studies, research studies, review articles, and government reports pertaining to epidemiology of lung cancer. CONCLUSION:Epidemiological evidence documents that most lu...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/s0749-2081(96)80023-4
更新日期:1996-11-01 00:00:00
abstract::This introduction lays the groundwork for this issue on a Collection of Oncology Nurses' Position Papers. Position papers developed by professional nursing organizations reflect a theoretical and research foundation. The position papers in this collection are relevant to oncology nurses in various practice settings an...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章
doi:10.1053/j.soncn.2004.02.001
更新日期:2004-05-01 00:00:00
abstract:OBJECTIVES:An overview of molecular tests used in the treatment of breast cancer, organized by stage and clinical condition. DATA SOURCES:Systematic review of scientific literature, guideline recommendations, and data published by test manufacturers. CONCLUSION:Several molecular tests that analyze expression of cance...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/j.soncn.2015.02.008
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVE:To review the current state of prostate cancer screening and future directions. DATA SOURCES:Nursing, medical and scientific literature related to prostate cancer screening, and national and international professional recommendations. CONCLUSION:Prostate cancer screening has been a topic of robust discussio...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/j.soncn.2017.02.003
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVES:To synthesize state of the knowledge collected in this volume and propose future directions for lesbian, gay, bisexual and transgender (LGBT) cancer practice, education, research, and advocacy. DATA SOURCES:Current and extant literature. CONCLUSION:Health care disparities that are known but not yet fully e...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/j.soncn.2017.12.007
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVES:To provide a review of genetic biomarkers of cancer risk and associated clinical implications. DATA SOURCES:Published literature, evidence-based guidelines. CONCLUSION:Identification of the genetic variation associated with cancer risk enables the health care provider to stratify an individual's risk and p...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/j.soncn.2012.03.007
更新日期:2012-05-01 00:00:00
abstract::Some of the special concerns of the dying patient have been addressed. Loss of control, adequate pain control, and sexuality represent only a small portion of the enormity of caring for dying patients. Great strides have been made in recent years both in the areas of special concerns and recognizing the anticipatory g...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章
doi:10.1016/0749-2081(89)90071-5
更新日期:1989-05-01 00:00:00
abstract:OBJECTIVES:To provide a review of the pathophysiology and corresponding signs and symptoms of tumor lysis syndrome (TLS); to review clinical and laboratory monitoring parameters. DATA SOURCES:Primary and tertiary literature and clinical experience. CONCLUSIONS:An understanding of the pathophysiology of TLS, meticulou...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/s0749-2081(02)80100-0
更新日期:2002-08-01 00:00:00