Serum antibodies and subsequent cervical neoplasms: a prospective study with 12 years of follow-up.

Abstract:

:Approximately 40,000 blood samples drawn in 1968-1972 by the Social Insurance Institution's mobile clinic in Finland have been stored. Linking cancer incidence data obtained from the Finnish Cancer Registry with this material yielded 32 cases of cervical cancer diagnosed after drawing of the blood sample. These 32 individuals and 64 matched controls were analyzed for serum antibodies indicative of past infection with Chlamydia trachomatis, Neisseria gonorrhoeae, cytomegalovirus, Epstein-Barr virus, and herpes simplex virus type 2. After adjustment for smoking and other sexually transmitted diseases, antibodies to C. trachomatis showed the strongest association with cervical cancer (odds ratio = 5.0 (95% confidence interval 1.6-15.7)), but the numbers were too small for drawing conclusions as to the sexually transmitted diseases with which cervical cancer is most specifically associated.

journal_name

Am J Epidemiol

authors

Hakama M,Lehtinen M,Knekt P,Aromaa A,Leinikki P,Miettinen A,Paavonen J,Peto R,Teppo L

doi

10.1093/oxfordjournals.aje.a116656

subject

Has Abstract

pub_date

1993-01-15 00:00:00

pages

166-70

issue

2

eissn

0002-9262

issn

1476-6256

journal_volume

137

pub_type

杂志文章
  • Childhood polymyositis: a case-control study.

    abstract::A case-control epidemiologic study of childhood polymyositis is presented. Parents of 42 cases of childhood polymyositis were interviewed along with parents of controls matched for sex and age. Extensive review of past medical history, animal exposure history, residential and family history, and immunization history f...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a112341

    authors: Koch MJ,Brody JA,Gillespie MM

    更新日期:1976-12-01 00:00:00

  • Low-dose exposure to asbestos and lung cancer: dose-response relations and interaction with smoking in a population-based case-referent study in Stockholm, Sweden.

    abstract::This population-based case-referent study investigated the lung cancer risk associated with occupational exposure to asbestos, focusing on dose-response relations and the interaction with tobacco smoking. Incident cases of lung cancer among males aged 40-75 years in Stockholm County, Sweden, were identified from 1985 ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/155.11.1016

    authors: Gustavsson P,Nyberg F,Pershagen G,Schéele P,Jakobsson R,Plato N

    更新日期:2002-06-01 00:00:00

  • Social network diversity and risks of ischemic heart disease and total mortality: findings from the Copenhagen City Heart Study.

    abstract::Measures of various types of social contacts were used as predictors of ischemic heart disease events and total mortality in an age-stratified random sample of 9,573 adults enrolled in the Copenhagen City Heart Study (Copenhagen, Denmark). Baseline examinations were conducted in 1991-1994, and participants were follow...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwi128

    authors: Barefoot JC,Grønbaek M,Jensen G,Schnohr P,Prescott E

    更新日期:2005-05-15 00:00:00

  • Serologic profile of children in a Mexican highland community: prevalence of complement-fixing antibodies to Mycoplasma pneumoniae, respiratory syncytial virus and parainfluenza viruses.

    abstract::The study investigated the prevalence of antibodies to five leading agents of childhood respiratory disease in the county of Huixquilucan, Mexico. Tests of sera from a random sample of children between 3 months and 18 years of age confirmed serologically the presence of Mycoplasma pneumoniae, respiratory syncytial (RS...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a112113

    authors: Golubjatnikov R,Allen VD,Olmos-Blancarte MP,Inhorn SL

    更新日期:1975-05-01 00:00:00

  • Risk of cancer and death in relation to serum cholesterol. A longitudinal study in an eastern Finnish population with high overall cholesterol level.

    abstract::The relationship of the risk of cancer and death to total serum cholesterol was studied in a random population sample from two counties of Eastern Finland. Data on total serum cholesterol were recorded between February and April 1972 for 3745 men and 4221 women aged 30 to 59 years who had no history of cancer, diabete...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a113445

    authors: Salonen JT

    更新日期:1982-10-01 00:00:00

  • The case of intoxicated cells-an epidemiologic note.

    abstract::An episode is described in which tissue culture in a laboratory could have become intoxicated due to the recirculation of toxic exhaust fumes extruded from the roof of a research institution. A route of entry was found whereby a portion of fume hood exhaust was reintroduced into the building by means of large intake f...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a113094

    authors: Cohen D,Wanner RG

    更新日期:1981-03-01 00:00:00

  • Hostility and trajectories of body mass index over 19 years: the Whitehall II Study.

    abstract::The authors examined the associations of hostility measured in adulthood with subsequent body mass index (BMI; weight (kg)/height (m)(2)) assessed at 4 time points over a 19-year period (1985-2004) in a United Kingdom cohort study. A total of 6,484 participants (4,494 men and 1,990 women) aged 35-55 years at baseline ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwn333

    authors: Nabi H,Kivimaki M,Sabia S,Dugravot A,Lajnef M,Marmot MG,Singh-Manoux A

    更新日期:2009-02-01 00:00:00

  • Effect of early patient enrollment on the time to completion and publication of randomized controlled trials.

    abstract::The authors evaluated whether early enrollment affects the significance of the results and the time to completion and publication of randomized controlled trials. Seventy-seven efficacy randomized controlled trials (total enrollment, 28,992 patients) initiated by the Acquired Immunodeficiency Syndrome Clinical Trials ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/154.9.873

    authors: Haidich AB,Ioannidis JP

    更新日期:2001-11-01 00:00:00

  • Low insulin sensitivity is associated with clustering of cardiovascular disease risk factors.

    abstract::Hyperinsulinemia is associated with multiple metabolic disorders including high triglyceride level, low high density lipoprotein (HDL) cholesterol level, hypertension, and impaired glucose tolerance (IGT). This metabolic constellation is also called the insulin resistance syndrome. All previous data on clustering of t...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a009272

    authors: Mykkänen L,Haffner SM,Rönnemaa T,Bergman RN,Laakso M

    更新日期:1997-08-15 00:00:00

  • The changing epidemiologic pattern of hepatitis A infection in urban Greece.

    abstract::The point prevalence of antibody to hepatitis A virus (anti-HAV) in a sample of 1,113 healthy Greek children and adolescents 0-19 years old was estimated by radioimmunoassay. The overall anti-HAV prevalence was 8.7%; it increased from almost zero among children less than four years of age to 16.3% in adolescents 15-19...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a113937

    authors: Kremastinou J,Kalapothaki V,Trichopoulos D

    更新日期:1984-11-01 00:00:00

  • Neonatal outcome following maternal antenatal depression and anxiety: a population-based study.

    abstract::The aim of this study was to determine neonatal outcomes among women who had depressive and anxiety disorders during the second trimester of pregnancy in a population-based sample. Participants were 1,465 women and their neonates born at two obstetric clinics in Sweden. The inclusion period for the women was October 2...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwh122

    authors: Andersson L,Sundström-Poromaa I,Wulff M,Aström M,Bixo M

    更新日期:2004-05-01 00:00:00

  • Protection against ischemic heart disease in the Belgian Physical Fitness Study: physical fitness rather than physical activity?

    abstract::Occupational and leisure time physical activity and conventional risk factors were determined in the Belgian Physical Fitness Study, a prospective study of 2,363 healthy male factory workers who were aged 40-55 years at entry in 1976-1978 and who were followed for five years. Physical fitness, defined as the interpola...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a114573

    authors: Sobolski J,Kornitzer M,De Backer G,Dramaix M,Abramowicz M,Degre S,Denolin H

    更新日期:1987-04-01 00:00:00

  • The relation between body mass index and plasma total cholesterol in a multiracial sample of US schoolchildren.

    abstract::The relation between body mass index expressed as weight in kilograms divided by height in meters cubed (weight (kg)/height (m3)) and plasma total cholesterol was assessed in a sample of 11,389 US schoolchildren, aged 5-18 years, between 1984 and 1989. Among whites and Hispanics, a statistically significant nonlinear ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a115751

    authors: Resnicow K,Morabia A

    更新日期:1990-12-01 00:00:00

  • Occupational exposure to whole-body vibration and Parkinson's disease: results from a population-based case-control study.

    abstract::Mechanical stress producing head injury is associated with Parkinson's disease, suggesting that relations with other physical hazards such as whole-body vibration (WBV) should be tested. In this study, the authors evaluated the relation between occupational exposure to WBV and Parkinson's disease. A population-based c...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kws017

    authors: Harris MA,Marion SA,Spinelli JJ,Tsui JK,Teschke K

    更新日期:2012-08-15 00:00:00

  • Duration of breastfeeding and risk of overweight: a meta-analysis.

    abstract::Observational studies suggest a longer duration of breastfeeding to be associated dose dependently with a decrease in risk of overweight in later life. The authors performed a comprehensive meta-analysis of the existing studies on duration of breastfeeding and risk of overweight. Studies were included that reported th...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章,meta分析

    doi:10.1093/aje/kwi222

    authors: Harder T,Bergmann R,Kallischnigg G,Plagemann A

    更新日期:2005-09-01 00:00:00

  • Long-term Pseudomonas colonization in spinal cord injury patients.

    abstract::In a previous study, patients with spinal cord injuries were observed to have a high incidence of colonizaion of the perineum, rectum, and urethra with Pseudomonas. In the current report, 10 men and 10 women with spinal cord injury were studied prospectively during their stay in hospital between June-Dec. 1977 (men) a...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a113020

    authors: Montgomerie JZ,Morrow JW

    更新日期:1980-10-01 00:00:00

  • Assessing the impact of additional follow-up in cohort studies.

    abstract::An approach is described for predicting the statistical value of extending follow-up in a cohort study. A simple approximation to the expected number of new events of interest is given. The effect of these events on inferences for parameters such as a standardized mortality ratio is approached in two ways. The first c...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a114040

    authors: Brookmeyer R,Day N,Pompe-Kirn V

    更新日期:1985-04-01 00:00:00

  • Short- and long-term prognosis after acute myocardial infarction in Chinese men and women.

    abstract::Most, but not all, studies in Western countries have indicated that women have a higher mortality than men after an acute myocardial infarction, but this has not been well documented in the developing world. The authors studied 601 male and 294 female myocardial infarction patients, aged 26-94 years, admitted to a cit...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a117059

    authors: He J,Klag MJ,Whelton PK,Zhoa Y,Weng X

    更新日期:1994-04-01 00:00:00

  • Risk of other cancers following Kaposi's sarcoma: relation to acquired immunodeficiency syndrome.

    abstract::To evaluate the risk of another cancer among persons who initially developed Kaposi's sarcoma, the authors used data from the Surveillance, Epidemiology, and End Results (SEER) program of the National Cancer Institute for the years 1973-1990. In persons under 70 years of age, 4,946 cases of Kaposi's sarcoma were obser...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a117008

    authors: Biggar RJ,Curtis RE,Cote TR,Rabkin CS,Melbye M

    更新日期:1994-02-15 00:00:00

  • Offspring birth weight and parental mortality: prospective observational study and meta-analysis.

    abstract::The authors have investigated associations between offspring size at birth and parental cardiovascular disease mortality among 12,086 mothers and 6,936 fathers of participants in the British 1958 birth cohort. Birth weight was inversely associated with all-cause mortality and cardiovascular mortality in both mothers a...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1093/aje/kwm054

    authors: Davey Smith G,Hyppönen E,Power C,Lawlor DA

    更新日期:2007-07-15 00:00:00

  • Arterial calcification found on breast cancer screening mammograms and cardiovascular mortality in women: The DOM Project. Doorlopend Onderzoek Morbiditeit en Mortaliteit.

    abstract::Breast arterial calcification (BAC) has been associated with diabetes and hypertension. This prompted the authors to study the relation between BAC and cardiovascular mortality in a cohort of 12,239 women aged 50-68 years who participated in a population-based breast cancer screening project (DOM Project) in Utrecht, ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a009455

    authors: Kemmeren JM,van Noord PA,Beijerinck D,Fracheboud J,Banga JD,van der Graaf Y

    更新日期:1998-02-15 00:00:00

  • Distinguishing the effects of maternal and offspring genes through studies of "case-parent triads".

    abstract::A gene variant that increases disease risk will be overrepresented among diseased persons, even compared with their own biologic parents. This insight has led to tests based solely on the asymmetric distribution of a variant allele among cases and their parents (e.g., the transmission/disequilibrium test). Existing me...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a009715

    authors: Wilcox AJ,Weinberg CR,Lie RT

    更新日期:1998-11-01 00:00:00

  • Invited commentary: interpreting associations between exposure biomarkers and pregnancy outcome.

    abstract::Levels of exposure biomarkers vary among individuals because of differences in both environmental exposure and metabolism. However, the ultimate interest is in providing information about the impact of modifying environmental exposures through regulation or behavior change. Using these levels in studies of pregnancy o...

    journal_title:American journal of epidemiology

    pub_type: 评论,杂志文章

    doi:10.1093/aje/kwt314

    authors: Savitz DA

    更新日期:2014-03-01 00:00:00

  • Life dissatisfactions, job dissatisfaction and illness of married men over time.

    abstract::This study examines the degree to which job and marital satisfaction and participation in leisure activities could predict concurrent and future health status relative to ethnicity, class and occupational factors, and mental health. Data were obtained from a longitudinal study of a random sample of 1034 Manhattan fami...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a112231

    authors: Gersten JC,Friis R,Langner TS

    更新日期:1976-03-01 00:00:00

  • Gestational exposure to rubella vaccinees: a population surveillance study.

    abstract::Over a two-year period an attempt was made to identify instances of transmission of rubella vaccine virus from rubella vaccinees to pregnant women in Nashville-Davidson County, Tennessee. Approximately 24,000 children were immunized in a mass campaign at the outset of the study. Several prospective surveillance method...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a112089

    authors: Fleet WF,Vaughn W,Lefkowitz LB Jr,Schaffner W,Federspiel CF

    更新日期:1975-03-01 00:00:00

  • Racial and Ethnic Disparities in the Incidence of Esophageal Cancer in the United States, 1992-2013.

    abstract::Racial and ethnic disparities in the incidence of esophageal cancer have not been thoroughly characterized with quantitative health-disparity measures. Using data from 1992-2013 from 13 US cancer registries in the Surveillance, Epidemiology, and End Results database, we assessed such disparities according to histologi...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwx221

    authors: Xie SH,Rabbani S,Petrick JL,Cook MB,Lagergren J

    更新日期:2017-12-15 00:00:00

  • Risk of second primary malignancies in women with papillary thyroid cancer.

    abstract::Second malignancies in women diagnosed with thyroid cancer are of concern given the young average age at diagnosis and excellent survival. Data from the California Cancer Registry were used to evaluate the risk of second primary cancers among a retrospective population-based cohort of 10,932 women diagnosed with papil...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwj072

    authors: Canchola AJ,Horn-Ross PL,Purdie DM

    更新日期:2006-03-15 00:00:00

  • New fatherhood and psychological distress: a longitudinal study of Australian men.

    abstract::Despite growing interest and concern about men's mental health during the perinatal period, we still do not know whether men are more vulnerable to mental health problems during this time. The current study is one of the first to use longitudinal, population-based data to investigate whether becoming an expectant and/...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwu177

    authors: Leach LS,Olesen SC,Butterworth P,Poyser C

    更新日期:2014-09-15 00:00:00

  • The C677T polymorphism in the methylenetetrahydrofolate reductase gene (MTHFR), maternal use of folic acid supplements, and risk of isolated clubfoot: A case-parent-triad analysis.

    abstract::Worldwide, 1-4 per 1,000 births are affected by clubfoot. Clubfoot etiology is unclear, but both genetic and environmental factors are thought to be involved. Low folate status in pregnant women has been implicated in several congenital malformations, and folate metabolism may be affected by polymorphisms in the methy...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwj285

    authors: Sharp L,Miedzybrodzka Z,Cardy AH,Inglis J,Madrigal L,Barker S,Chesney D,Clark C,Maffulli N

    更新日期:2006-11-01 00:00:00

  • Observations on the history of epidemiology in western New York, 1843-1960.

    abstract::Epidemiology has a rich tradition in western New York State, beginning with the classic study by Austin Flint of a waterborne typhoid fever outbreak in North Boston in 1843. Other important investigations included the study of the Buffalo poliomyelitis epidemic of 1912, by Wade Hampton Frost, which provided a comprehe...

    journal_title:American journal of epidemiology

    pub_type: 历史文章,杂志文章

    doi:10.1093/oxfordjournals.aje.a009215

    authors: Winkelstein W Jr

    更新日期:1997-12-01 00:00:00