Abstract:
:Approximately 40,000 blood samples drawn in 1968-1972 by the Social Insurance Institution's mobile clinic in Finland have been stored. Linking cancer incidence data obtained from the Finnish Cancer Registry with this material yielded 32 cases of cervical cancer diagnosed after drawing of the blood sample. These 32 individuals and 64 matched controls were analyzed for serum antibodies indicative of past infection with Chlamydia trachomatis, Neisseria gonorrhoeae, cytomegalovirus, Epstein-Barr virus, and herpes simplex virus type 2. After adjustment for smoking and other sexually transmitted diseases, antibodies to C. trachomatis showed the strongest association with cervical cancer (odds ratio = 5.0 (95% confidence interval 1.6-15.7)), but the numbers were too small for drawing conclusions as to the sexually transmitted diseases with which cervical cancer is most specifically associated.
journal_name
Am J Epidemioljournal_title
American journal of epidemiologyauthors
Hakama M,Lehtinen M,Knekt P,Aromaa A,Leinikki P,Miettinen A,Paavonen J,Peto R,Teppo Ldoi
10.1093/oxfordjournals.aje.a116656subject
Has Abstractpub_date
1993-01-15 00:00:00pages
166-70issue
2eissn
0002-9262issn
1476-6256journal_volume
137pub_type
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