Mycosis fungoides plaque stage treated with topical nitrogen mustard with and without attempts at tolerance induction: report from the Scandinavian mycosis fungoides study group.

Abstract:

:The Scandinavian Mycosis Fungoides Study Group has treated 21 patients with mycosis fungoides in plaque stages with topical, whole-body application of nitrogen mustard, 20 mg in 40 ml water per square metre. Ten patients were treated after previous attempts at intravenous tolerance induction ad modum van Scott & Kalmanson and eleven without. Complete remission was initially achieved in 10 patients and partial remission in 9 patients. Contact dermatitis to nitrogen mustard developed in 2/10 after tolerance induction and in 1/11 without tolerance induction. It is concluded that topical, whole-body application of nitrogen mustard gives high remission rates. In this series, however, many relapses occurred, due to inadequacy of the maintenance treatment. Tolerance induction has not been found of any value.

journal_name

Acta Derm Venereol

authors

Molin L,Thomsen K,Volden G

subject

Has Abstract

pub_date

1979-01-01 00:00:00

pages

64-8

issue

1

eissn

0001-5555

issn

1651-2057

journal_volume

59

pub_type

杂志文章
  • Elevated colchicine sensitivity of dermal lymphocytes in mycosis fungoides.

    abstract::Lymphocytes in chronic lymphocytic leukaemia and in other malignant lymphomas exhibit an extreme sensitivity to colchicine and are cytolysed in vitro by 10(-6) M colchicine. This characteristic can be quantified with the colchicine sensitivity index which is used for diagnostic purposes. We have demonstrated that lymp...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Sterry W,Steigleder GK,Nikolai B

    更新日期:1980-01-01 00:00:00

  • Enzyme release from cultured human melanoma cells.

    abstract::The lysosomal enzyme beta-hexosaminidase and the melanocyte specific enzyme tyrosinase were examined in human melanoma cell cultures. The beta-hexosaminidase activity of the medium was approximately 40% of the total cellular activity after 24 h, while after 48 h the activity in the medium was twice that of the cells. ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:102340/0001555570286290

    authors: Karg E,Hultberg B,Isaksson A,Rosengren E,Rorsman H

    更新日期:1990-01-01 00:00:00

  • Cutaneous infection caused by Ulocladium chartarum in a heart transplant recipient: case report and review.

    abstract::A cutaneous mycoses caused by Ulocladium chartarum in a heart transplant recipient is reported. The infection cleared after complete surgical excision and 6 months of oral itraconazole therapy. In vitro activity of amphotericin B, fluconazole, itraconazole, voriconazole, ravuconazole and terbinafine against the clinic...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章,评审

    doi:10.1080/00015550310007256

    authors: Durán MT,Del Pozo J,Yebra MT,Crespo MG,Paniagua MJ,Cabezón MA,Guarro J

    更新日期:2003-01-01 00:00:00

  • Scratch induction in the rat by intradermal serotonin: a model for pruritus.

    abstract::Eight substances (histamine, compound 48/80, kallikrein, trypsin, papain, substance P, serotonin and platelet activating factor) were injected intradermally (volume 50 microl) into the rostral back (neck) of rats in order to establish an animal model for peripherally elicited pruritus. While serotonin induced excessiv...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.1080/00015550152572868

    authors: Thomsen JS,Petersen MB,Benfeldt E,Jensen SB,Serup J

    更新日期:2001-08-01 00:00:00

  • Thalidomide treatment of prurigo nodularis.

    abstract::Four patients with classic recalcitrant prurigo nodularis had symptomatic and physical responses to thalidomide with remissions. Three of the four patients had increased IgE levels that decreased during therapy. In two patients, short-term treatment (2 to 3 months) was not sufficient to produce remission, but retreatm...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Winkelmann RK,Connolly SM,Doyle JA,Padilha-Goncalves A

    更新日期:1984-01-01 00:00:00

  • Cutaneous adverse drug reactions seen at a university hospital department of dermatology.

    abstract::Patients with suspected cutaneous adverse drug reactions are often referred to allergy clinics or departments of dermatology for evaluation. These patients are selected compared with patients identified in prospective and cross-sectional studies of hospital populations. This explains the observed variation in prevalen...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-0153

    authors: Borch JE,Andersen KE,Bindslev-Jensen C

    更新日期:2006-01-01 00:00:00

  • In vitro migration of human mononuclear cells towards a psoriatic scale extract.

    abstract::Extracts of psoriatic scales from patients with chronic plaque psoriasis and of normal human post-mortem skin were tested for their effects on the migration of healthy human mononuclear cells in a modified Boyden chamber. A preparation of cells containing 12-32% monocytes was obtained from whole blood by a density gra...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Sterling JC,Lidén S

    更新日期:1984-01-01 00:00:00

  • Patch testing with a textile dye mix in two concentrations - a multicentre study by the Swedish contact dermatitis research group.

    abstract:UNLABELLED:Disperse dyes, which are used for colouring synthetic textile fibres, are well-known contact sensitisers. To investigate the outcome of patch-testing with a textile dye mix (TDM) at 7 dermatology clinics in Sweden, a TDM tested at 2 concentrations was included into the baseline series during one year. The mi...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章,多中心研究

    doi:10.2340/00015555-1956

    authors: Ryberg K,Bråred-Christensson J,Engfeldt M,Isaksson M,Lindberg M,Matura M,Stenberg B,Svedman C,Bruze M

    更新日期:2015-04-01 00:00:00

  • Recall bias in childhood atopic diseases among adults in the Odense Adolescence Cohort Study.

    abstract::Atopic dermatitis (AD) is a common disease in childhood and an important risk factor for the later development of other atopic diseases. Many publications on childhood AD use questionnaires based on information obtained in adulthood, which introduce the possibility of recall bias. In a prospective cohort study, recall...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-2128

    authors: Mortz CG,Andersen KE,Bindslev-Jensen C

    更新日期:2015-11-01 00:00:00

  • Inhibitory effect of vasoactive intestinal polypeptide and ketanserin on established allergic contact dermatitis in man.

    abstract::Neuromediators may influence the immune response. To investigate their potential immunomodulating role in established allergic contact dermatitis in man, the following neuromediators were tested: vasoactive intestinal polypeptide (VIP), serotonin, and the serotonin antagonists ketanserin, methiotepine and ICS-205-930....

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/0001555576102106

    authors: Bondesson L,Nordlind K,Mutt V,Lidén S

    更新日期:1996-03-01 00:00:00

  • Does long-term treatment with D-penicillamine alter calcium and phosphorus metabolism in patients with systemic sclerosis?

    abstract::Only animal experiments have been published regarding the possible effect of penicillamine treatment on mineral balance. We examined 35 patients with a diagnosis of systemic sclerosis treated with penicillamine, in comparison with 10 patients with systemic sclerosis treated with other collagen inhibitors (glutamine, h...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Hagdrup H,Serup J,Tvedegaard E

    更新日期:1983-01-01 00:00:00

  • Bromocriptine treatment in patients with late onset acne and idiopathic hyperprolactinemia.

    abstract::Twenty female patients with late onset acne and idiopathic hyperprolactinemia--but without increased levels of androgens or decreased levels of SHBG--were treated with bromocriptine. All patients had a fall of basal prolactin levels to normal and a great improvement in or even disappearance of their acne. ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Peserico A,Ruzza G,Veller Fornasa C,Bertoli P,Cipriani R

    更新日期:1988-01-01 00:00:00

  • Ulcerous lesions disclosing cutaneous infection with Fusarium solani.

    abstract::Fusarium spp. are emergent opportunistic moulds capable of producing life-threatening diseases, usually in immunocompromised hosts. When they infect immunocompetent patients, they usually cause localized diseases. We describe here a case of cutaneous fusariosis in a patient with a medical history of diabetes mellitus ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-0276

    authors: Pérez-Pérez L,Pereiro M Jr,Sánchez-Aguilar D,Toribio J

    更新日期:2007-01-01 00:00:00

  • A study of nineteen immunocompromised patients with extensive skin lesions caused by Pseudomonas aeruginosa with and without bacteremia.

    abstract::Nineteen immunocompromised patients with extensive skin lesions caused by Pseudomonas aeruginosa with or without P. aeruginosa bacteremia were analysed. Patients whose lesions originated in the skin were in the majority (14 patients). Skin lesions were located at the site of entry of bacteria (apocrine areas in 12 pat...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: el Baze P,Thyss A,Vinti H,Deville A,Dellamonica P,Ortonne JP

    更新日期:1991-01-01 00:00:00

  • Itch and mental distress: a cross-sectional study among late adolescents.

    abstract::Itch is known to be associated with psychological factors in adults, but has not been explored among adolescents. A cross-sectional, questionnaire-based population study involving adolescents born mostly in 1986 was carried out in 2004. A total of 4744 individuals were invited and the participation rate was 80%. The H...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-0554

    authors: Halvorsen JA,Dalgard F,Thoresen M,Thoresen M,Bjertness E,Lien L

    更新日期:2009-01-01 00:00:00

  • Induction of UVA pigmentation in pressure areas by hydrogen peroxide.

    abstract::Heavy external pressure, caused by the weight of the body when lying on a hard transparent surface during UVA irradiation, prevents pigmentation in pressure exposed skin areas. After percutaneous H2O2 administration a delayed pigmentation appeared on the pressure sites. This finding provides evidence for the role of o...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Tegner E,Björnberg A

    更新日期:1986-01-01 00:00:00

  • Seborrheic dermatitis and daylight.

    abstract::Patients with mood depression have been found to have a higher prevalence of seborrheic dermatitis (SD), possibly related to their tendency to live indoors. The prevalence of outpatients with SD has now been found to be directly related to the number of gloomy days in the area. Since UV light might not be the only rea...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Maietta G,Rongioletti F,Rebora A

    更新日期:1991-01-01 00:00:00

  • Validation of the Itch Severity Item as a Measurement Tool for Pruritus in Patients with Psoriasis: Results from a Phase 3 Tofacitinib Program.

    abstract::Tofacitinib is an oral Janus kinase inhibitor. This post-hoc analysis aimed to investigate the psychometric properties of the Itch Severity Item (ISI), a numeric rating scale from 0 (no itching) to 10 (worst possible itching) for pruritus in psoriasis, and review the effect of tofacitinib on pruritus in patients with ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-2856

    authors: Ständer S,Luger T,Cappelleri JC,Bushmakin AG,Mamolo C,Zielinski MA,Tallman AM,Yosipovitch G

    更新日期:2018-03-13 00:00:00

  • Anhidrotic effect of intradermal injections of botulinum toxin: a comparison of different products and concentrations.

    abstract::Botulinum toxin is used in various fields of medicine, including in the treatment of hyperhidrosis. Three products containing botulinum toxin are commercially available in Sweden; Botox, Dysport and Neurobloc. In the literature dose-response has varied with respect to these 3 products. We hypothesized that the dilutio...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-0419

    authors: Rystedt A,Swartling C,Naver H

    更新日期:2008-01-01 00:00:00

  • Long-term Sequelae of Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis.

    abstract::Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe cutaneous adverse drug reactions characterized by different extents of epidermal necrosis and mucosal breakdown. A limited number of studies have reported the long-term patterns of SJS and TEN complications in patient populations over long ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-2295

    authors: Yang CW,Cho YT,Chen KL,Chen YC,Song HL,Chu CY

    更新日期:2016-05-01 00:00:00

  • Development of gastric dysfunction in dermatitis herpetiformis.

    abstract::In order to study the development of atrophic gastritis, gastric secretory function was examined by a standard pentagastrin test 24 to 78 months after a previous examination (Ex I). The study included 12 patients with dermatitis herpetiformis (DH), 6 patients with functional signs of atrophic gastritis previously, and...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Stockbrügger R,Kastrup W,Lundqvist G,Mobacken H

    更新日期:1978-01-01 00:00:00

  • Rosacea: a cutaneous marker of Helicobacter pylori infection? Results of a pilot study.

    abstract::Given the long purported anecdotal association between rosacea and gastrointestinal disease, the discovery that Helicobacter pylori causes gastritis and duodenal ulcer disease has led to a hypothesized role for this organism in the aetiology of rosacea. We conducted a case-series study of 49 patients to assess the pot...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.1080/00015550310016544

    authors: Diaz C,O'Callaghan CJ,Khan A,Ilchyshyn A

    更新日期:2003-01-01 00:00:00

  • Cadherin 11 Involved in Basement Membrane Damage and Dermal Changes in Melasma.

    abstract::Basement membrane (BM) disruption and dermal changes (elastosis, collagenolysis, vascular ectasia) have been reported in melasma. Although ultraviolet (UV) irradiation can induce these changes, UV is not always necessary for melasma development. Cadherin 11 (CDH11), which is upregulated in some melasma patients, has p...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-2315

    authors: Kim NH,Choi SH,Lee TR,Lee CH,Lee AY

    更新日期:2016-06-15 00:00:00

  • Study of the Exposome Ageing-related Factors in the Spanish Population.

    abstract::To characterize the exposome of the Spanish population and its association with skin ageing a cross-sectional epidemiological study was conducted in men and women (18-60 years old). A total of 1,474 participants were included. Mean age (± standard deviation) was 40.84 ± 10.26 years. Most participants had Fitzpatrick s...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-3500

    authors: Buendía-Eisman A,Prieto L,Abarquero M,Arias-Santiago S

    更新日期:2020-05-28 00:00:00

  • Evaluation of port wine stain perfusion by laser Doppler imaging and thermography before and after argon laser treatment.

    abstract::Thirteen patients with port wine stains (PWS) were treated with argon laser therapy. Before and at different points in time following treatment, skin blood perfusion and temperature were mapped with laser Doppler imaging and thermography. In nine patients no elevation in blood perfusion was observed in the PWS in comp...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:102340/0001555572610

    authors: Troilius A,Wårdell K,Bornmyr S,Nilsson GE,Ljunggren B

    更新日期:1992-01-01 00:00:00

  • Erythropoietic protoporphyria and terminal hepatic failure.

    abstract::We report on a 44-year-old patient with erythropoietic protoporphyria who could effectively control his photosensitivity for 22 years with oral carotinoids. The clinical course of his disorder was complicated by liver involvement, initially expressed as marginally raised serum transaminase levels for several years. Te...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/0001555576453456

    authors: Bruch-Gerharz D,Bolsen K,Gerharz CD,Goerz G

    更新日期:1996-11-01 00:00:00

  • The cutaneous signs of eating disorders.

    abstract::Anorexia nervosa and bulimia nervosa are common yet occult eating disorders which each affect between 1 and 2% of young adult women in the UK (1). Cutaneous signs may provide valuable clues allowing earlier diagnosis. Eating disorders may both imitate (Table I) and complicate other medical illnesses, resulting in unne...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555746869

    authors: Siddiqui A,Ramsay B,Leonard J

    更新日期:1994-01-01 00:00:00

  • Identification of mononuclear cells infiltrating basal cell carcinomas.

    abstract::The identification of mononuclear cells extracted from 12 basal cell carcinomas has been carried out by means of various assays such as the E rosette test, FITC anti-Ig conjugates and peroxidase conjugates viewed at an ultrastructural level. The relative quantities of B and T cells have been determined as well as the ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Claudy AL,Viac J,Schmitt D,Alario A,Thivolet J

    更新日期:1976-01-01 00:00:00

  • The functions of polymorphonuclear leukocytes emigrating into the skin.

    abstract::The functions of polymorphonuclear leukocytes (PMNs) emigrating into the skin and of others separated simultaneously from the circulation were determined and compared in healthy individuals. The PMNs emigrating into the skin were separated with a skin chamber technique. The C3 rosette forming capacities of the skin mi...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Csato M,Dobozy A,Raith L,Simon N

    更新日期:1985-01-01 00:00:00

  • Remission of ordinary psoriasis following a short clearance course of cyclosporin.

    abstract::We set out to show that the assumption is incorrect that continuous treatment with cyclosporin is necessary in psoriasis, as this tenet forms a basis for current recommended treatment regimens. Sixty patients with mild to moderate plaque psoriasis were allocated at random to treatment with oral cyclosporin 5 mg/kg/day...

    journal_title:Acta dermato-venereologica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.2340/00015555756569

    authors: Levell NJ,Shuster S,Munro CS,Friedmann PS

    更新日期:1995-01-01 00:00:00