Effect of increased plasma non-esterified fatty acid concentrations on endurance performance during beta-adrenoceptor blockade.

Abstract:

:Inhibition of adipose tissue lipolysis, leading to a reduced availability of non-esterified fatty acids for energy production in the active skeletal muscles, may be involved in the impairment of endurance exercise capacity after administration of a beta-adrenoceptor blocking agent. The effect of increasing the availability of plasma NEFA during exercise after beta-blocker administration was studied. In a double-blind, randomized cross-over study 12 healthy volunteers were treated for 14 days with placebo, atenolol, and propranolol. On the 7th and 14th day of each treatment period an endurance exercise test at 70% of maximal aerobic power until exhaustion was performed while a continuous infusion of saline or triglycerides (Intralipid)+heparin was administered. Endurance time was reduced by 11% (n.s.) during atenolol and 40% (p < 0.01) during propranolol. Intralipid administration had no statistically significant effect on endurance in any treatment. Plasma NEFA and glycerol concentrations were elevated above control levels during Intralipid infusion, plasma glucose and lactate concentrations were unaffected. These results suggest that reduced availability of NEFA is not a major factor in the reduction of endurance performance during beta-adrenoceptor blockade, although an effect of beta-blockade on NEFA membrane transport cannot be excluded.

journal_name

Int J Sports Med

authors

van Baak MA,Mooij JM,Wijnen JA

doi

10.1055/s-2007-1021137

subject

Has Abstract

pub_date

1993-01-01 00:00:00

pages

2-8

issue

1

eissn

0172-4622

issn

1439-3964

journal_volume

14

pub_type

临床试验,杂志文章,随机对照试验
  • Comparison of hematologic data in world elite junior speed skaters and in non-athletic juniors.

    abstract::During the world junior speed skating championship 2002 all athletes (60 males, 56 females) were subjected to hematologic blood testing one day before the competition as requested by International Skating Union--ISU. This study aimed to obtain hematological reference values for junior athletes, whilst the influence of...

    journal_title:International journal of sports medicine

    pub_type: 杂志文章

    doi:10.1055/s-2005-865676

    authors: Mayr A,Kuipers H,Falk M,Santer P,Wierer B

    更新日期:2006-04-01 00:00:00

  • Heart rate responses during a breath-holding competition in well-trained divers.

    abstract::The diving response elicited by breath-holding (BH) and immersion mainly consists of bradycardia, decreased cardiac output, and peripheral vasoconstriction. These responses reduce oxygen consumption and thereby prolong the duration of the dive. They may also lead to cardiac arrhythmias or hypoxia, however, which in tu...

    journal_title:International journal of sports medicine

    pub_type: 临床试验,杂志文章

    doi:10.1055/s-2004-821159

    authors: Lemaître F,Bernier F,Petit I,Renard N,Gardette B,Joulia F

    更新日期:2005-07-01 00:00:00

  • The Construct Validity of the CODA and Repeated Sprint Ability Tests in Football Referees.

    abstract::As of 2017, the international football federation introduced the change of direction ability test (CODA) and the 5×30 m sprint test for assistant referees (ARs) and continued the 6×40 m sprint test for field referees (FRs) as mandatory tests. The aim of this study was to evaluate the association between performance in...

    journal_title:International journal of sports medicine

    pub_type: 杂志文章

    doi:10.1055/a-0577-4073

    authors: Riiser A,Andersen V,Castagna C,Pettersen SA,Saeterbakken A,Froyd C,Ylvisaker E,Naess Kjosnes T,Fusche Moe V

    更新日期:2018-07-01 00:00:00

  • Side effects of anabolic androgenic steroids abuse.

    abstract::Long-term side effects of high doses of anabolic androgenic steroids self-administration were evaluated in this study. Twenty male bodybuilders, voluntarily starting steroid self-administration, were followed every 6 months over 2 years. Physical examination, haematological, metabolic and endocrine variables, semen an...

    journal_title:International journal of sports medicine

    pub_type: 杂志文章

    doi:10.1055/s-2007-965808

    authors: Bonetti A,Tirelli F,Catapano A,Dazzi D,Dei Cas A,Solito F,Ceda G,Reverberi C,Monica C,Pipitone S,Elia G,Spattini M,Magnati G

    更新日期:2008-08-01 00:00:00

  • Non-invasive measurements of O2 availability in human skeletal muscle with near-infrared spectroscopy.

    abstract::The availability of O2 in the human vastus lateralis muscle has been investigated with non-invasive near-infrared spectroscopy (NIRS) using a commercially available unit (RunMan, NIM Inc. Philadelphia). The measuring probe placed above the skin illuminates the underlying tissue and measures the reflected light at two ...

    journal_title:International journal of sports medicine

    pub_type: 杂志文章

    doi:10.1055/s-2007-1024625

    authors: Sahlin K

    更新日期:1992-10-01 00:00:00

  • Effects of controlled frequency breathing during exercise on blood gases and acid-base balance.

    abstract::The purpose of this study was to determine the effect of a reduced ventilatory frequency (Vf) on blood gases and acid-base changes during three intensities of cycling exercise. VO2max and lactate threshold workload (LaT) of six subjects were assessed on a Monark ergometer. Experimental rides were performed 1) with no ...

    journal_title:International journal of sports medicine

    pub_type: 杂志文章

    doi:10.1055/s-2007-1024657

    authors: Sharp RL,Williams DJ,Bevan L

    更新日期:1991-02-01 00:00:00

  • Hemoglobin, hematocrit, and calculated plasma volume changes induced by a short, supramaximal task.

    abstract::The influence of a short, supramaximal task of 30 s duration on plasma volume (PV) was tested in 14 female physical education students. Hemoglobin (Hb), hematocrit (Hct), and osmolality (Osm) were tested pre- and post-exercise. Performance of the exercise test, consisting of 30 s all-out pedaling against a load of 4.4...

    journal_title:International journal of sports medicine

    pub_type: 杂志文章

    doi:10.1055/s-2008-1026093

    authors: Rotstein A,Bar-Or O,Dlin R

    更新日期:1982-11-01 00:00:00

  • Evaluation of the Accusport lactate analyser.

    abstract::It has been suggested that lactate concentrations may provide a guide to an optimal training intensity. However, lactate concentrations established during incremental exercise in the laboratory are not always indicative of what is occurring during constant-load exercise at the same intensity. Ideally, lactate concentr...

    journal_title:International journal of sports medicine

    pub_type: 杂志文章

    doi:10.1055/s-2001-17611

    authors: Bishop D

    更新日期:2001-10-01 00:00:00

  • Physiologic comparison of competitive racewalking and running.

    abstract::Eight competitive racewalkers were studied to determine a) the speed where running and racewalking become equally efficient, b) if, at a similar VO2, the physiologic responses to submaximal exercise differ between running and racewalking, and c) if VO2 max can be attained during racewalking. The speed at which running...

    journal_title:International journal of sports medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1055/s-2008-1025883

    authors: Hagberg JM,Coyle EF

    更新日期:1984-04-01 00:00:00

  • Effect of inertia on performance and fatigue pattern during repeated cycle sprints in males and females.

    abstract::The effect of recovery duration on performance and fatigue pattern during short exercises was studied including and excluding the flywheel inertia. Subjects (11 males and 11 females) performed a force-velocity test to determine their optimal force (f (opt)). On the following day, subjects performed randomly 4 series o...

    journal_title:International journal of sports medicine

    pub_type: 杂志文章

    doi:10.1055/s-2003-45262

    authors: Falgairette G,Billaut F,Giacomoni M,Ramdani S,Boyadjian A

    更新日期:2004-04-01 00:00:00

  • Influence of endurance training on plasma amino acid concentrations in humans at rest and after intense exercise.

    abstract::The influence of exercise training on plasma amino acid concentrations at rest and after exercise was examined in a highly trained group of humans and compared with the response of a control group of nontrained healthy humans. After a bout of intense exercise at the same relative work load, the trained group exhibited...

    journal_title:International journal of sports medicine

    pub_type: 杂志文章

    doi:10.1055/s-2007-1024908

    authors: Einspahr KJ,Tharp G

    更新日期:1989-08-01 00:00:00

  • Phase Angle is Determined by Body Composition and Cardiorespiratory Fitness in Adolescents.

    abstract::The phase angle is used to evaluate nutritional status and is an indicator of cellular health. Cardiorespiratory fitness and body composition are strong indicators of health during adolescence. We aimed to evaluate if body composition and cardiorespiratory fitness have an association with phase angle among adolescents...

    journal_title:International journal of sports medicine

    pub_type: 杂志文章

    doi:10.1055/a-1152-4865

    authors: Langer RD,de Fatima Guimarães R,Gonçalves EM,Guerra-Junior G,de Moraes AM

    更新日期:2020-08-01 00:00:00

  • Vertical leg stiffness following ankle taping and bracing.

    abstract::This study sought to determine if prophylactic ankle taping and bracing influenced vertical leg stiffness during hopping. Twenty healthy and physically active participants completed testing under three ankle stabilizer conditions, ankle tape, semi-rigid ankle brace or control (no stabilizer) during three separate sess...

    journal_title:International journal of sports medicine

    pub_type: 杂志文章

    doi:10.1055/s-0028-1105930

    authors: Williams S,Riemann BL

    更新日期:2009-05-01 00:00:00

  • Influence of Age and Pathology on Achilles Tendon Properties During a Single-leg Jump.

    abstract::Prevalence of Achilles tendinopathy increases with age leading to a weaker tendon with predisposition to rupture. Conclusive evidence of the influence of age and pathology on Achilles tendon (AT) properties remains limited, as previous studies are based on standardized isometric conditions. The study investigates the ...

    journal_title:International journal of sports medicine

    pub_type: 杂志文章

    doi:10.1055/s-0042-108198

    authors: Intziegianni K,Cassel M,Rauf S,White S,Rector M,Kaplick H,Wahmkow G,Kratzenstein S,Mayer F

    更新日期:2016-11-01 00:00:00

  • Acute effects of distribution of rest between repetitions.

    abstract::The purpose of this study was to compare acute mechanical and metabolic effects of 2 sessions of resistance training equated by volume and total resting time but with different set configuration: sets to failure (FS) vs. distribution of rest between each repetition (NFS). 10 male judoists completed a session consistin...

    journal_title:International journal of sports medicine

    pub_type: 杂志文章

    doi:10.1055/s-0031-1299699

    authors: Iglesias-Soler E,Carballeira E,Sánchez-Otero T,Mayo X,Jiménez A,Chapman ML

    更新日期:2012-05-01 00:00:00

  • The acute immune response to exhaustive resistance exercise.

    abstract::Ten young male adults (mean age 46.9 +/- 1.2 yrs) with 9.2 +/- 1.4 years of weight training experience and the ability to parallel squat at least 1.5 times their body mass were selected as subjects. The exercise session consisted of sets of 10 repetitions at 65% 1-RM of the parallel leg squat, with a cadence of one re...

    journal_title:International journal of sports medicine

    pub_type: 杂志文章

    doi:10.1055/s-2007-973013

    authors: Nieman DC,Henson DA,Sampson CS,Herring JL,Suttles J,Conley M,Stone MH,Butterworth DE,Davis JM

    更新日期:1995-07-01 00:00:00

  • Pulmonary mechanics and entrainment of respiration and stroke rate during rowing.

    abstract::During rowing, the respiratory musculature is confronted with dual demands: assisting the propulsive force generation and as the effector for ventilatory control. We determined the pulmomechanical and breathing pattern features of rowing-induced hyperpnea in five national class rowers (18 years old). Each subject perf...

    journal_title:International journal of sports medicine

    pub_type: 杂志文章

    doi:10.1055/s-2007-1021217

    authors: Steinacker JM,Both M,Whipp BJ

    更新日期:1993-09-01 00:00:00

  • Creatine supplementation as an ergogenic aid for sports performance in highly trained athletes: a critical review.

    abstract::Creatine supplementation has become a common practice among competition athletes participating in different sports over the last few years. The mechanism by which supplementary creatine could have potential ergogenic effects would be an increased muscle creatine and phosphocreatine concentration, leading to a higher r...

    journal_title:International journal of sports medicine

    pub_type: 杂志文章,meta分析

    doi:10.1055/s-2007-972670

    authors: Mujika I,Padilla S

    更新日期:1997-10-01 00:00:00

  • Demonstration of the need for cardiovascular and pulmonary normative data for cancer survivors.

    abstract::Despite evidence that cancer and its treatments severely reduce cardiorespiratory fitness (CRF), normative data for cancer survivors do not exist. The present study identifies age and gender-specific CRF distributions in a cancer population. The use of cancer-specific normative CRF data may help stratify initial fitne...

    journal_title:International journal of sports medicine

    pub_type: 杂志文章

    doi:10.1055/s-0034-1375691

    authors: Schneider CM,Repka CP,Brown JM,Lalonde TL,Dallow KT,Barlow CE,Hayward R

    更新日期:2014-12-01 00:00:00

  • Haemostasis at high altitude.

    abstract::Haemostasis has been studied by several authors during exposure to altitude hypoxia. On acute induction to hypoxia, platelet count, platelet aggregability and bleeding time are normal; an increase of thromboxane released from platelets and of prostacyclin, released from endothelial cells is observed; coagulation facto...

    journal_title:International journal of sports medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-2007-1024592

    authors: Le Roux G,Larmignat P,Marchal M,Richalet JP

    更新日期:1992-10-01 00:00:00

  • Aerobic fitness influences the response of maximal oxygen uptake and lactate threshold in acute hypobaric hypoxia.

    abstract::We studied 12 highly trained athletes, 6 male ice-hockey players and 6 cross-country skiers (2 females, 4 males). All of them participated in a maximal electrically braked bicycle ergometer test in a hypobaric chamber at the simulated altitude of 3000m (520 mmHg) and in normobaric conditions two days apart in random o...

    journal_title:International journal of sports medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1055/s-2007-972968

    authors: Koistinen P,Takala T,Martikkala V,Leppäluoto J

    更新日期:1995-02-01 00:00:00

  • Gait Retraining From Rearfoot Strike to Forefoot Strike does not change Running Economy.

    abstract::Gait retraining is a method for management of patellofemoral pain, which is a common ailment among recreational runners. The present study investigated the effects of gait retraining from rearfoot strike to forefoot strike on running economy, heart rate, and respiratory exchange ratio immediately post-retraining and o...

    journal_title:International journal of sports medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1055/s-0043-110225

    authors: Roper JL,Doerfler D,Kravitz L,Dufek JS,Mermier C

    更新日期:2017-12-01 00:00:00

  • Incidence rate of injuries during sport activity and physical exercise in a rural Swedish municipality: incidence rates in 17 sports.

    abstract::A prospective study of acute injuries from sports and physical exercise was carried out during 1 year in a total population of a municipality with 31,620 inhabitants. Data on exposure were collected: the number of participants in each sport, the hours of participation, and number of weeks in the season per year. The n...

    journal_title:International journal of sports medicine

    pub_type: 杂志文章

    doi:10.1055/s-2007-1025052

    authors: de Loës M,Goldie I

    更新日期:1988-12-01 00:00:00

  • Anaerobic running capacity determined from a 3-parameter systems model: relationship with other anaerobic indices and with running performance in the 800 m-run.

    abstract::The purpose of this study was to compare anaerobic running capacity (ARC, i.e., the distance that can be run using only stored energy sources in the muscle) determined from a 3-parameter systems model with other anaerobic indices and with running performance in the 800 m. Seventeen trained male subjects (.VO(2max) = 6...

    journal_title:International journal of sports medicine

    pub_type: 杂志文章

    doi:10.1055/s-2006-924516

    authors: Bosquet L,Delhors PR,Duchene A,Dupont G,Leger L

    更新日期:2007-06-01 00:00:00

  • Energy expenditure in rock/pop drumming.

    abstract::Despite the vigorous nature of rock/pop drumming, there are no precise data on the energy expenditure of this activity. The aim of this study was to quantify the energy cost of rock/pop drumming. Fourteen male drummers (mean±SD; age 27±8 yrs.) completed an incremental drumming test to establish the relationship betwee...

    journal_title:International journal of sports medicine

    pub_type: 杂志文章

    doi:10.1055/s-0033-1337905

    authors: De La Rue SE,Draper SB,Potter CR,Smith MS

    更新日期:2013-10-01 00:00:00

  • The nutritional intake of Bolivian boys. The relation between altitude and socioeconomic status.

    abstract::The nutrition of 57 native Bolivian boys living at high altitude (HA) in La Paz (+/- 4000 m) and of 63 boys living at low altitude (LA) in St. Cruz (+/- 400 m) is described. The dietary information was obtained with a 24-h recall method, by interviewing the child and mother. The food items are listed in household meas...

    journal_title:International journal of sports medicine

    pub_type: 杂志文章

    doi:10.1055/s-2007-1021121

    authors: Post GB,Lujan C,San Miquel JL,Kemper HC

    更新日期:1994-04-01 00:00:00

  • Acute and chronic over-exertion: do depressed immune responses provide useful markers?

    abstract::There are ethical objections to inducing cumulative muscle damage and associated decrements of performance deliberately in a healthy athlete. Available data on acute and chronic over-exertion thus include the changes of immune response observed following a single bout of exhausting exercise, sequential observations ma...

    journal_title:International journal of sports medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-2007-971898

    authors: Shephard RJ,Shek PN

    更新日期:1998-04-01 00:00:00

  • 12 weeks of simulated barefoot running changes foot-strike patterns in female runners.

    abstract::To investigate the effect of a transition program of simulated barefoot running (SBR) on running kinematics and foot-strike patterns, female recreational athletes (n=9, age 29 ± 3 yrs) without SBR experience gradually increased running distance in Vibram FiveFingers SBR footwear over 12 weeks. Matched controls (n=10, ...

    journal_title:International journal of sports medicine

    pub_type: 杂志文章

    doi:10.1055/s-0033-1353215

    authors: McCarthy C,Fleming N,Donne B,Blanksby B

    更新日期:2014-05-01 00:00:00

  • Blood lactate and heat stress during training in rowers.

    abstract::The purpose of the present study was to test the hypothesis that large increases in blood lactate concentration ([La] (b)) and/or body temperature may occur during an endurance training on a rowing ergometer and disrupt training. The influence of an increase in air convection on the capacity to perform a prolonged exe...

    journal_title:International journal of sports medicine

    pub_type: 杂志文章

    doi:10.1055/s-2007-965067

    authors: Maciejewski H,Messonnier L,Moyen B,Bourdin M

    更新日期:2007-11-01 00:00:00

  • Motor symptoms similar to parkinsonism in heavy smokers.

    abstract::The major objective in this study was a comparison of the motor performance of young male smokers and non-smokers. We tested the endurance capacity, maximal isometric strength, speed of whole-body movements, flexibility and balancing ability of 74 smokers and 118 non-smokers. Then we measured the balancing ability, th...

    journal_title:International journal of sports medicine

    pub_type: 杂志文章

    doi:10.1055/s-2007-1021048

    authors: Burtscher M,Likar R,Pechlaner C,Kunz F,Philadelphy M

    更新日期:1994-05-01 00:00:00