The prevalence of coronary heart disease in the multi-ethnic and high diabetes prevalence population of Mauritius.

Abstract:

:The prevalence of coronary heart disease (CHD) was determined in a population survey in Mauritius where the prevalence of non-insulin dependent diabetes and mortality from CHD are amongst the highest in the world. Men and women aged 35-74 years of all major ethnic groups were included: Asian Indians (Hindus and Muslims), Creoles and Chinese. ECG abnormalities suggesting either 'probable CHD' or 'possible CHD' were defined using standard criteria. The overall prevalence of probable CHD was 2.7% in men and 0.9% in women, and that of probable or possible CHD together 17.8% in men and 33.3% in women. The prevalence of CHD did not vary significantly between the four ethnic groups. In the multivariate analyses, age and high blood pressure were the most important independent predictors of ECG abnormalities. Neither diabetes nor serum insulin seemed to contribute independently to the prevalence of CHD. This survey confirmed the high ranking of Mauritius in international mortality statistics. The high rates of CHD seen in Asian Indians, African-origin Creoles and Chinese in the rapidly developing country of Mauritius may be a pointer to future problems in their regions of origin.

journal_name

J Intern Med

authors

Tuomilehto J,Li N,Dowse G,Gareeboo H,Chitson P,Fareed D,Min Z,Alberti KG,Zimmet P

doi

10.1111/j.1365-2796.1993.tb00672.x

subject

Has Abstract

pub_date

1993-02-01 00:00:00

pages

187-94

issue

2

eissn

0954-6820

issn

1365-2796

journal_volume

233

pub_type

杂志文章
  • Impact of a high-dose nitrate strategy on cardiac stress in acute heart failure: a pilot study.

    abstract:BACKGROUND:Intravenous nitrate therapy has been shown to improve short-term outcome of acute heart failure patients treated in the intensive care unit. The potential of a noninvasive high-dose nitrate strategy in the Emergency Department and the general ward remains unknown. METHODS:A total of 128 consecutive acute he...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/j.1365-2796.2009.02146.x

    authors: Breidthardt T,Noveanu M,Potocki M,Reichlin T,Egli P,Hartwiger S,Socrates T,Gayat E,Christ M,Mebazaa A,Mueller C

    更新日期:2010-03-01 00:00:00

  • Coeliac disease and noncoeliac wheat or gluten sensitivity.

    abstract::Coeliac disease (CD) and noncoeliac wheat or gluten sensitivity (NCWS/NCGS) are common gluten-related disorders. Both conditions can present with gastrointestinal and extraintestinal manifestations, which can be a challenge for physicians to discern between. Whilst coeliac serology and histological assessment are requ...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1111/joim.13120

    authors: Rej A,Aziz I,Sanders DS

    更新日期:2020-11-01 00:00:00

  • Future generations of red blood cell substitutes.

    abstract::Polyhaemoglobins (PolyHb) and perfluorochemicals are in advanced phase III clinical trials and conjugated haemoglobins in phase II clinical trial. New recombinant human haemoglobin with no vasoactivity is being developed. A soluble macromolecule of PolyHb-catalase-superoxide dismutase is being studied as an oxygen car...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1046/j.1365-2796.2003.01151.x

    authors: Chang TM

    更新日期:2003-05-01 00:00:00

  • Combined effects of obesity and physical activity in predicting mortality among men.

    abstract:OBJECTIVE:We evaluated the hypothesis that higher levels of total daily physical activity can eliminate the increased mortality rate associated with overweight and obesity. DESIGN:Population-based prospective cohort study. SETTING:Central Sweden. SUBJECTS:A total of 37,633 men at baseline 45-79 years of age and free...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/j.1365-2796.2008.01985.x

    authors: Orsini N,Bellocco R,Bottai M,Pagano M,Michaelsson K,Wolk A

    更新日期:2008-11-01 00:00:00

  • Liver fibrosis attributed to lipid lowering medications: two cases.

    abstract::We identified two cases of chronic active hepatitis with liver fibrosis induced by lipid lowering drugs of the statin and fibrate classes despite regular monitoring of transaminases. There are few reports of clinically significant hepatitis induced by these drugs and even fewer cases of fibrosis. Given the growing use...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1046/j.1365-2796.2001.00848.x

    authors: Punthakee Z,Scully LJ,Guindi MM,Ooi TC

    更新日期:2001-09-01 00:00:00

  • Haemoglobin-vesicles as artificial oxygen carriers: present situation and future visions.

    abstract::During the long history of development of haemoglobin (Hb)-based O2 carriers (HBOCs), many side effects of Hb molecules have become apparent. They imply the physiological importance of the cellular structure of red blood cells. Hb-vesicles (HbV) are artificial O2 carriers that encapsulate concentrated Hb solution with...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2796.2007.01893.x

    authors: Sakai H,Sou K,Horinouchi H,Kobayashi K,Tsuchida E

    更新日期:2008-01-01 00:00:00

  • Primary and secondary prevention in cardiovascular disease: an old-fashioned concept?

    abstract:OBJECTIVE:Is the concept of primary and secondary cardiovascular prevention an old-fashioned concept that needs to be re-defined? DESIGN:Discussion paper. RESULTS:Cardiovascular prevention means reduction of absolute risk for cardiovascular disease (CVD), irrespective of clinical stage. CONCLUSION:For the calculatio...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1046/j.1365-2796.2002.00962.x

    authors: van Venrooij FV,Stolk RP,Banga JD,Erkelens DW,Grobbee DE

    更新日期:2002-04-01 00:00:00

  • D-dimer levels and risk of recurrence following provoked venous thromboembolism: findings from the RIETE registry.

    abstract:BACKGROUND:Patients with venous thromboembolism (VTE) secondary to transient risk factors may develop VTE recurrences after discontinuing anticoagulation. Identifying at-risk patients could help to guide the duration of therapy. METHODS:We used the RIETE database to assess the prognostic value of d-dimer testing after...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/joim.12969

    authors: Avnery O,Martin M,Bura-Riviere A,Barillari G,Mazzolai L,Mahé I,Marchena PJ,Verhamme P,Monreal M,Ellis MH,RIETE Investigators.

    更新日期:2020-01-01 00:00:00

  • A patient with TSC1 germline mutation whose clinical phenotype was limited to lymphangioleiomyomatosis.

    abstract:BACKGROUND:Lymphangioleiomyomatosis (LAM) can occur as in isolated form (sporadic LAM) or as a pulmonary manifestation of tuberous sclerosis complex (TSC) (TSC-associated LAM). Recent studies, however, revealed that both forms of LAM are genetically related but that sporadic LAM is a distinct clinical entity caused by ...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2796.2004.01356.x

    authors: Sato T,Seyama K,Kumasaka T,Fujii H,Setoguchi Y,Shirai T,Tomino Y,Hino O,Fukuchi Y

    更新日期:2004-08-01 00:00:00

  • Drugs and femoral neck fracture: a case-control study.

    abstract::Two hundred consecutive patients with femoral neck fractures (FNF) and 200 controls matched by age, sex, nursing home residency and number of admissions within the last 2 years, were interviewed about recent drug use. The matching criteria were chosen to achieve case and control groups that were comparable with regard...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/j.1365-2796.1991.tb00302.x

    authors: Jensen J,Nielsen LH,Lyhne N,Hallas J,Brøsen K,Gram LF

    更新日期:1991-01-01 00:00:00

  • Physical activity and risk of cognitive decline: a meta-analysis of prospective studies.

    abstract:OBJECTIVE:The relationship between physical activity and cognitive function is intriguing but controversial. We performed a systematic meta-analysis of all the available prospective studies that investigated the association between physical activity and risk of cognitive decline in nondemented subjects. METHODS:We con...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/j.1365-2796.2010.02281.x

    authors: Sofi F,Valecchi D,Bacci D,Abbate R,Gensini GF,Casini A,Macchi C

    更新日期:2011-01-01 00:00:00

  • Combination of budesonide/formoterol more effective than fluticasone/salmeterol in preventing exacerbations in chronic obstructive pulmonary disease: the PATHOS study.

    abstract:OBJECTIVES:Combinations of inhaled corticosteroids (ICSs) and long-acting β2 -agonists (LABAs) are recommended for patients with moderate and severe chronic obstructive pulmonary disease (COPD). However, it is not known whether different fixed combinations are equally effective. The aim of this study was to investigate...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/joim.12067

    authors: Larsson K,Janson C,Lisspers K,Jørgensen L,Stratelis G,Telg G,Ställberg B,Johansson G

    更新日期:2013-06-01 00:00:00

  • High rate of nonspecific anti-hepatitis C reactivity amongst homosexual men in comparison with that found in other sexually active groups and blood donors. Viral Hepatitis and AIDS Study Group.

    abstract:OBJECTIVES:To investigate the concordance of anti-hepatitis C virus (anti-HCV) reactivity by a second-generation enzyme immunoassay (EIA-2) and by a four-antigen recombinant immunoblot assay (4-RIBA) in homosexual men, in comparison with that found in other sexually active groups and blood donors. DESIGN:Prospective s...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/j.1365-2796.1994.tb01122.x

    authors: Andreu J,Abad MA,Sanchez-Quijano A,Torronteras R,Luque F,Garcia de las Heras J,Soto B,Pineda JA,Leal M,Lissen E

    更新日期:1994-07-01 00:00:00

  • Health, health care utilization and living conditions in foreign-born diabetic patients in southern Sweden.

    abstract:OBJECTIVES:To compare foreign- and Swedish-born diabetic subjects regarding health care utilization, complications, clinical and socio-economic characteristics. DESIGN:Cross-sectional study. SETTING:All known diabetic patients living in six defined primary health care districts. SUBJECTS:Of 1861 identified subjects ...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1046/j.1365-2796.1997.00161.x

    authors: Hjelm K,Apelqvist J,Nyberg P,Sundquist J,Isacsson A

    更新日期:1997-08-01 00:00:00

  • Cold exposure increases cyclic guanosine monophosphate in healthy women but not in women with Raynaud's phenomenon.

    abstract:OBJECTIVE:To investigate influence of whole-body cooling on cyclic GMP (cGMP) in women with Raynaud's phenomenon and in healthy women. DESIGN:The study was performed as an open, parallel-group comparison between women with Raynaud's phenomenon and healthy women during the winter month of February. SETTING:The municip...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/j.1365-2796.1995.tb00875.x

    authors: Leppert J,Ringqvist A,Ahlner J,Myrdal U,Sørensen S,Ringqvist I

    更新日期:1995-05-01 00:00:00

  • Cracking the neural code, treating paralysis and the future of bioelectronic medicine.

    abstract::The human nervous system is a vast network carrying not only sensory and movement information, but also information to and from our organs, intimately linking it to our overall health. Scientists and engineers have been working for decades to tap into this network and 'crack the neural code' by decoding neural signals...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1111/joim.12610

    authors: Bouton C

    更新日期:2017-07-01 00:00:00

  • One year's experience of early defibrillation in Stockholm.

    abstract::The effects of resuscitation on patients who died suddenly out of hospital were evaluated after the introduction of early defibrillation performed by ambulance personnel using semi-automatic defibrillators. Resuscitation attempts were initiated in 548 patients during the 1-year study period. Mean ambulance delay was 7...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/j.1365-2796.1989.tb00085.x

    authors: Jakobsson J,Rehnqvist N,Nyquist O

    更新日期:1989-05-01 00:00:00

  • Determinants of carotid intima-media thickness: a population-based ultrasonography study in eastern Finnish men.

    abstract::We investigated the determinants of maximal intima-media thickness of common carotid arteries in a population-based sample of 1224 Eastern Finnish men aged 42, 48, 54 or 60 years. A high-resolution B-mode ultrasonographic examination was performed as part of the Kuopio Ischaemic Heart Disease Risk Factor Study (KIHD)....

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/j.1365-2796.1991.tb00336.x

    authors: Salonen R,Salonen JT

    更新日期:1991-03-01 00:00:00

  • Narrow hips and broad waist circumferences independently contribute to increased risk of non-insulin-dependent diabetes mellitus.

    abstract:OBJECTIVES:Patients with non-insulin-dependent diabetes mellitus (NIDDM) have been shown to be more obese and have higher waist-to-hips circumference ratios compared to nondiabetics. In this study, we tried to dissociate obesity, waist and hip circumference from NIDDM. DESIGN:A cross-sectional population-based case-co...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1046/j.1365-2796.1997.00235.x

    authors: Seidell JC,Han TS,Feskens EJ,Lean ME

    更新日期:1997-11-01 00:00:00

  • Effect of folic acid and betaine on fasting and postmethionine-loading plasma homocysteine and methionine levels in chronic haemodialysis patients.

    abstract:OBJECTIVES:To study fasting and postmethionine-loading (increment and decrement) plasma homocysteine levels in end-stage renal disease (ESRD) patients in relation to B-vitamin status and after folic acid treatment without or with betaine. DESIGN:Plasma total homocysteine (tHcy) and methionine levels were measured in c...

    journal_title:Journal of internal medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1365-2796.1999.00430.x

    authors: van Guldener C,Janssen MJ,de Meer K,Donker AJ,Stehouwer CD

    更新日期:1999-02-01 00:00:00

  • Multiple risk intervention trial in high risk hypertensive men: comparison of ultrasound intima-media thickness and clinical outcome during 6 years of follow-up.

    abstract:OBJECTIVES:The objective was to analyse whether a favourable change in risk factors, caused by a comprehensive risk factor modification programme, affected intima-media thickness (IMT) in the common carotid artery, and whether any such change was associated with a change in cardiovascular events during a 6-year follow-...

    journal_title:Journal of internal medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1365-2796.2001.00818.x

    authors: Agewall S,Fagerberg B,Berglund G,Schmidt C,Wendelhag I,Wikstrand J,Risk Factor Intervention Study Group, Sweden.

    更新日期:2001-04-01 00:00:00

  • The role of clonal haematopoiesis in cardiovascular diseases: epidemiology and experimental studies.

    abstract::Clonal haematopoiesis results from acquired mutations in haematopoietic stem and progenitor cells (HSPCs). These mutations can confer the HSPC with a competitive advantage, leading to their clonal expansion within the limiting bone marrow niche. This process is often insufficient to produce a haematologic malignancy; ...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/joim.13130

    authors: Min KD,Kour A,Sano S,Walsh K

    更新日期:2020-11-01 00:00:00

  • A cardiac sodium channel mutation identified in Brugada syndrome associated with atrial standstill.

    abstract::Mutations in the cardiac Na+ channel gene SCN5A are responsible for multiple lethal ventricular arrhythmias including Brugada syndrome and congenital long QT syndrome. Here we report a case of Brugada syndrome with ST elevation in the right precordial and inferior leads accompanied by atrial standstill and spontaneous...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1046/j.0954-6820.2003.01247.x

    authors: Takehara N,Makita N,Kawabe J,Sato N,Kawamura Y,Kitabatake A,Kikuchi K

    更新日期:2004-01-01 00:00:00

  • Constitutive RET tyrosine kinase activation in hereditary medullary thyroid cancer: clinical opportunities.

    abstract::The ground-breaking discovery of genotype-phenotype relationships in hereditary medullary thyroid cancer has greatly facilitated early prophylactic thyroidectomy. Its timing depends not solely on a positive gene test but, more importantly, on the type of the REarranged during Transfection (RET) mutation and its underl...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2796.2009.02113.x

    authors: Machens A,Lorenz K,Dralle H

    更新日期:2009-07-01 00:00:00

  • Infection of mural thrombus: a case report and literature review.

    abstract::Infection of mural thrombus over an area of old myocardial infarct was found in an elderly woman with cholangitis. This case is unique since cholangitis was thought to be the cause of septicaemia and ventricular aneurysm was not present. ...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2796.1990.tb00159.x

    authors: Cheung A,Choi A

    更新日期:1990-04-01 00:00:00

  • What else adds to hypertension in predicting stroke? An incident case-referent study.

    abstract:OBJECTIVES:To examine to what extent traditional biomedical risk factors and social factors can predict, separately or jointly, first-ever stroke event, and to explore to what extent other risk factors might add to hypertension/elevated blood pressure as a stroke risk factor. DESIGN:An incident case-referent study. S...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1046/j.1365-2796.2000.00746.x

    authors: Ohgren B,Weinehall L,Stegmayr B,Boman K,Hallmans G,Wall S

    更新日期:2000-12-01 00:00:00

  • Treatment with apo B peptide vaccines inhibits atherosclerosis in human apo B-100 transgenic mice without inducing an increase in peptide-specific antibodies.

    abstract:OBJECTIVES:Autoantibodies to apolipoprotein (apo) B-100 peptides are present in human plasma and have been shown to be associated with decreased cardiovascular risk. The present study aimed to determine if apo B-100 peptide vaccines are atheroprotective in mice expressing human apo B-100 and if the effectiveness of the...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/j.1365-2796.2008.01995.x

    authors: Fredrikson GN,Björkbacka H,Söderberg I,Ljungcrantz I,Nilsson J

    更新日期:2008-12-01 00:00:00

  • Effect of lifibrol on the metabolism of low density lipoproteins and cholesterol.

    abstract::Lifibrol is a powerful cholesterol-lowering drug of unknown mechanism of action. This investigation was carried out to determine whether the major action of lifibrol is to enhance clearance of low density lipoproteins (LDL) through the LDL-receptor pathway, and if so, whether the drug exerts its action by altering the...

    journal_title:Journal of internal medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1365-2796.1999.00536.x

    authors: Vega GL,von Bergmann K,Grundy SM,Blumenschein S,Carter NB,Laeis P,Lindenthal B,von Bergmann J,Simatupang A,Lutjohann D,Adams-Huet B

    更新日期:1999-07-01 00:00:00

  • Effects of long-term treatment with metoprolol and hydrochlorothiazide on plasma lipids and lipoproteins.

    abstract::In order to evaluate the effects of one-year antihypertensive treatment on plasma lipids and lipoproteins, 65 patients whose diastolic blood pressure was in the range 95-120 mmHg were randomly allocated to groups that received either hydrochlorothiazide or metoprolol, or both drugs when the response to one of them was...

    journal_title:Journal of internal medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2796.1990.tb00240.x

    authors: Monmany J,Domingo P,Gomez JA,Sanz F,Roca-Cusachs A,Nolla J,Jane F

    更新日期:1990-10-01 00:00:00

  • Helicobacter pylori: resurrection of the cancer link.

    abstract::Helicobacter pylori is one of the most common pathogenic bacterial infections, colonizing an estimated half of all humans. In a subset of individuals, the infection leads to serious gastroduodenal disease such as peptic ulcers and gastric adenocarcinoma. The factors contributing to skewing this, in most cases benign, ...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1046/j.1365-2796.2003.01119.x

    authors: Björkholm B,Falk P,Engstrand L,Nyrén O

    更新日期:2003-02-01 00:00:00