Lactate dehydrogenase A as a highly abundant eye lens protein in platypus (Ornithorhynchus anatinus): upsilon (upsilon)-crystallin.

abstract：:Protamines are small, highly basic DNA-binding proteins found in the sperm of animals. Interestingly, the proportion of arginine residues in one type of protamine, protamine P1, is about 50% in mammals. Upon closer examination, it was found that both the total number of amino acids and the positions of arginine residu...

journal_title：Molecular biology and evolution

authors： Rooney AP,Zhang J,Nei M

更新日期：2000-02-01 00:00:00

abstract：:Cysteine-rich secretory proteins (CRISPs) are glycoproteins found exclusively in vertebrates and have broad diversified functions. They are hypothesized to play important roles in mammalian reproduction and in reptilian venom, where they disrupt homeostasis of the prey through several mechanisms, including among other...

journal_title：Molecular biology and evolution

authors： Sunagar K,Johnson WE,O'Brien SJ,Vasconcelos V,Antunes A

更新日期：2012-07-01 00:00:00

abstract：:Many intron positions are conserved in varying subsets of eukaryotic genomes and, consequently, comprise a potentially informative class of phylogenetic characters. Roy and Gilbert developed a method of phylogenetic reconstruction using the patterns of intron presence-absence in eukaryotic genes and, applying this met...

journal_title：Molecular biology and evolution

authors： Zheng J,Rogozin IB,Koonin EV,Przytycka TM

更新日期：2007-11-01 00:00:00

abstract：:Thyroid hormones are involved in the regulation of growth and metabolism in all vertebrates. Transthyretin is one of the extracellular proteins with high affinity for thyroid hormones which determine the partitioning of these hormones between extracellular compartments and intracellular lipids. During vertebrate evolu...

journal_title：Molecular biology and evolution

authors： Prapunpoj P,Richardson SJ,Fumagalli L,Schreiber G

更新日期：2000-08-01 00:00:00

abstract：:It is known that the effective population size (Ne) and the mutation rate (u) vary across the genome. Here, we show that ignoring this heterogeneity may lead to biased estimates of past demography. To solve the problem, we develop new methods for jointly inferring past changes in population size and detecting variatio...

journal_title：Molecular biology and evolution

authors： Zeng K,Jackson BC,Barton HJ

更新日期：2019-02-01 00:00:00

abstract：:Vitamin B(12) (cobalamin) is a dietary requirement for humans because it is an essential cofactor for two enzymes, methylmalonyl-CoA mutase and methionine synthase (METH). Land plants and fungi neither synthesize or require cobalamin because they do not contain methylmalonyl-CoA mutase, and have an alternative B(12)-i...

journal_title：Molecular biology and evolution

authors： Helliwell KE,Wheeler GL,Leptos KC,Goldstein RE,Smith AG

更新日期：2011-10-01 00:00:00

abstract：:The diversity of color vision systems found in extant vertebrates suggests that different evolutionary selection pressures have driven specializations in photoreceptor complement and visual pigment spectral tuning appropriate for an animal's behavior, habitat, and life history. Aquatic vertebrates in particular show h...

journal_title：Molecular biology and evolution

authors： Hart NS,Lamb TD,Patel HR,Chuah A,Natoli RC,Hudson NJ,Cutmore SC,Davies WIL,Collin SP,Hunt DM

更新日期：2020-03-01 00:00:00

abstract：:The genetic basis of organisms' adaptation to different environments is a central issue of molecular evolution. The budding yeast Saccharomyces cerevisiae and its relatives predominantly ferment glucose into ethanol even in the presence of oxygen. This was suggested to be an adaptation to glucose-rich habitats, but th...

journal_title：Molecular biology and evolution

authors： Lin Z,Li WH

更新日期：2011-01-01 00:00:00

abstract：:The complete nucleotide sequence of the mt (mitochondrial) and cp (chloroplast) genomes of the unicellular green alga Ostreococcus tauri has been determined. The mt genome assembles as a circle of 44,237 bp and contains 65 genes. With an overall average length of only 42 bp for the intergenic regions, this is the most...

journal_title：Molecular biology and evolution

authors： Robbens S,Derelle E,Ferraz C,Wuyts J,Moreau H,Van de Peer Y

更新日期：2007-04-01 00:00:00

abstract：:Molecular evolutionary rates within two protistan and three metazoan taxa were estimated using divergence times derived from fossil records. The results indicate that the small-subunit rRNA sequences within Dasycladales (Chlorophyta) and Bacillariophyceae evolved at a rate approximately two to three times faster than ...

journal_title：Molecular biology and evolution

authors： Sorhannus U

更新日期：1996-09-01 00:00:00

abstract：:We implement a Bayesian Markov chain Monte Carlo algorithm for estimating species divergence times that uses heterogeneous data from multiple gene loci and accommodates multiple fossil calibration nodes. A birth-death process with species sampling is used to specify a prior for divergence times, which allows easy asse...

journal_title：Molecular biology and evolution

authors： Yang Z,Rannala B

更新日期：2006-01-01 00:00:00

abstract：:This study examines molecular relationships across a wide range of species in the mass spawning scleractinian coral genus Acropora. Molecular phylogenies were obtained for 28 species using DNA sequence analyses of two independent markers, a nuclear intron and the mtDNA putative control region. Although the composition...

journal_title：Molecular biology and evolution

authors： van Oppen MJ,McDonald BJ,Willis B,Miller DJ

更新日期：2001-07-01 00:00:00

abstract：:The quantitative immunological technique of micro-complement fixation (MC'F) has been routinely used during the past decade to assess evolutionary relationships among living vertebrate species. The large data base that has been generated, along with the excellent correlations between immunologically measured genetic d...

journal_title：Molecular biology and evolution

authors： Maxson RD,Maxson LR

更新日期：1986-09-01 00:00:00

abstract：:Selection on codon usage bias is well documented in a number of microorganisms. Whether codon usage is also generally shaped by natural selection in large organisms, despite their relatively small effective population size (Ne), is unclear. In animals, the population genetics of codon usage bias has only been studied ...

journal_title：Molecular biology and evolution

authors： Galtier N,Roux C,Rousselle M,Romiguier J,Figuet E,Glémin S,Bierne N,Duret L

更新日期：2018-05-01 00:00:00

abstract：:The ancestral selection graph, conditioned on the allelic types in the sample, is used to obtain a limiting gene genealogical process under strong selection. In an equilibrium, two-allele system with strong selection, neutral gene genealogies are predicted for random samples and for samples containing at most one unfa...

journal_title：Molecular biology and evolution

authors： Wakeley J

更新日期：2008-12-01 00:00:00

abstract：:Genetic variation in contemporary South Asian populations follows a northwest to southeast decreasing cline of shared West Eurasian ancestry. A growing body of ancient DNA evidence is being used to build increasingly more realistic models of demographic changes in the last few thousand years. Through high-quality mode...

journal_title：Molecular biology and evolution

authors： Yelmen B,Mondal M,Marnetto D,Pathak AK,Montinaro F,Gallego Romero I,Kivisild T,Metspalu M,Pagani L

更新日期：2019-08-01 00:00:00

abstract：:A major theoretical consequence of selection at a locus is the genetic hitchhiking of linked sites (selective sweep). The extent of hitchhiking around a gene is related to the strength of selection and the rate of recombination, with its impact diminishing with distance from the selected site. At the Rop-1 locus of th...

journal_title：Molecular biology and evolution

authors： Rose CJ,Chapman JR,Marshall SD,Lee SF,Batterham P,Ross HA,Newcomb RD

更新日期：2011-06-01 00:00:00

abstract：:Assessing the influence of three-dimensional protein structure on sequence evolution is a difficult task, mainly because of the assumption of independence between sites required by probabilistic phylogenetic methods. Recently, models that include an explicit treatment of protein structure and site interdependencies ha...

journal_title：Molecular biology and evolution

authors： Kleinman CL,Rodrigue N,Lartillot N,Philippe H

更新日期：2010-07-01 00:00:00

abstract：:Bacterial plasmids substantially contribute to the rapid spread of antibiotic resistance, which is a crisis in healthcare today. Coevolution of plasmids and their hosts promotes this spread of resistance by ameliorating the cost of plasmid carriage. However, our knowledge of plasmid-bacteria coevolution is solely base...

journal_title：Molecular biology and evolution

authors： Stalder T,Cornwell B,Lacroix J,Kohler B,Dixon S,Yano H,Kerr B,Forney LJ,Top EM

更新日期：2020-06-01 00:00:00

abstract：:Dinoflagellate chloroplast genes are unique in that each gene is on a separate minicircular chromosome. To understand the origin and evolution of this exceptional genomic organization we completely sequenced chloroplast psbA and 23S rRNA gene minicircles from four dinoflagellates: three closely related Heterocapsa spe...

journal_title：Molecular biology and evolution

authors： Zhang Z,Cavalier-Smith T,Green BR

更新日期：2002-04-01 00:00:00

abstract：:DNA fingerprinting exhibits multilocus genotypes of individuals, detected by the use of a single multilocus probe. Consequently, population data on DNA fingerprinting do not provide a complete characterization of the genetic variation in terms of allele-frequency distributions, since neither the number of loci nor the...

journal_title：Molecular biology and evolution

authors： Jin L,Chakraborty R

更新日期：1994-01-01 00:00:00

abstract：:The human Y chromosome consists of ampliconic genes, which are located in palindromes and undergo frequent gene conversion, and single-copy genes including the primary sex-determining locus, SRY. Here, we demonstrate that SRY is duplicated in a large palindrome in the European rabbit (Oryctolagus cuniculus). Furthermo...

journal_title：Molecular biology and evolution

authors： Geraldes A,Rambo T,Wing RA,Ferrand N,Nachman MW

更新日期：2010-11-01 00:00:00

abstract：:The Mlc1 gene of Drosophila melanogaster encodes two MLC1 isoforms via developmentally regulated alternative pre-mRNA splicing. In larval muscle and tubular and abdominal muscles of adults, all of the six exons are included in the spliced mRNA, whereas, in the fibrillar indirect flight muscle of adult, exon 5 is exclu...

journal_title：Molecular biology and evolution

authors： Leicht BG,Lyckegaard EM,Benedict CM,Clark AG

更新日期：1993-07-01 00:00:00

abstract：:Morphological innovations like the acquisition of the neural crest as well as gene family expansions by genome duplication are considered as major leaps in the evolution of the vertebrate lineage. Using comparative genomic analyses, we have reconstructed the evolutionary history of the endothelin system, a signaling p...

journal_title：Molecular biology and evolution

authors： Braasch I,Volff JN,Schartl M

更新日期：2009-04-01 00:00:00

abstract：:Although there is substantial evidence that, in animals, male-inherited neutral DNA evolves at a higher rate than female-inherited DNA, the relative evolutionary rate of male- versus female-inherited DNA has not been investigated in plants. We compared the substitution rates at neutral sites of maternally and paternal...

journal_title：Molecular biology and evolution

authors： Whittle CA,Johnston MO

更新日期：2002-06-01 00:00:00

abstract：:The mitoribosome, as known from studies in model organisms, deviates considerably from its ancestor, the bacterial ribosome. Deviations include substantial reduction of the mitochondrial ribosomal RNA (mt-rRNA) structure and acquisition of numerous mitochondrion-specific (M) mitoribosomal proteins (mtRPs). A broadly a...

journal_title：Molecular biology and evolution

authors： Valach M,Alcazar JAG,Sarrasin M,Lang BF,Gray MW,Burger G

更新日期：2020-09-04 00:00:00

abstract：:Homeobox genes encode transcription factors involved in many aspects of developmental processes. The homeodomain-leucine zipper (HD-Zip) genes, which are characterized by the presence of both a homeodomain and a leucine zipper motif, form a clade within the homeobox superfamily and were previously reported only from v...

journal_title：Molecular biology and evolution

authors： Sakakibara K,Nishiyama T,Kato M,Hasebe M

更新日期：2001-04-01 00:00:00

abstract：:Epigenetic information, which can be passed on independently of the DNA sequence, is stored in part in the form of histone posttranslational modifications and specific histone variants. Although complexes necessary for deposition have been identified for canonical and variant histones, information regarding the chroma...

journal_title：Molecular biology and evolution

authors： Ashraf K,Nabeel-Shah S,Garg J,Saettone A,Derynck J,Gingras AC,Lambert JP,Pearlman RE,Fillingham J

更新日期：2019-05-01 00:00:00

abstract：:There is increasing evidence that dosage compensation is not a ubiquitous feature following sex chromosome evolution, especially not in organisms where females are the heterogametic sex, like in birds. Even when it occurs, compensation can be incomplete and limited to dosage-sensitive genes. However, previous work has...

journal_title：Molecular biology and evolution

authors： Uebbing S,Konzer A,Xu L,Backström N,Brunström B,Bergquist J,Ellegren H

更新日期：2015-10-01 00:00:00

abstract：:The spacer between the 16S and 23S rRNA genes of the chloroplast DNA has been implicated as an origin of replication in several species of plants. In the evening primrose, Oenothera, this site was found to vary greatly in size, with plastid genomes (plastomes) being readily distinguished. To determine whether plastome...

journal_title：Molecular biology and evolution

authors： Sears BB,Stoike LL,Chiu WL

更新日期：1996-07-01 00:00:00