Abstract：
:A bovine brain calmodulin-dependent protein kinase undergoes autophosphorylation with a maximal incorporation of 10 mol phosphate per mol enzyme. The autophosphorylated enzyme is fully active, independent of Ca2+ and calmodulin. Although the autophosphorylation reaction depends on Ca2+ and calmodulin, it can be rendered Ca(2+)-independent after about 15 seconds when 1 mol phosphate has been incorporated per mol enzyme. This Ca(2+)-independent autophosphorylation is an intramolecular reaction, since mixing of autophosphorylated and non-phosphorylated calmodulin-dependent protein kinase does not result in the Ca(2+)-independent phosphorylation of the non-phosphorylated enzyme. The Ca(2+)-independent autophosphorylation can be inhibited by an exogenous substrate, e.g., casein. The casein phosphorylation activity is approximately proportional to the level of phosphorylation of the enzyme.
journal_name
Biochem Biophys Res Communjournal_title
Biochemical and biophysical research communicationsauthors
Zhang GY,Wang JH,Sharma RKdoi
10.1006/bbrc.1993.1269subject
Has Abstractpub_date
1993-03-15 00:00:00pages
669-74issue
2eissn
0006-291Xissn
1090-2104pii
S0006-291X(83)71269-6journal_volume
191pub_type
杂志文章abstract：:The cDNA coding for the signal peptide of rat liver mitochondrial aldehyde dehydrogenase was sequenced. The deduced amino acid sequence of the signal peptide was MLRAALSTARRGPRLSRLL. From this sequence an amphiphilic helix which had a high hydrophobic moment could be constructed. A comparison to the published cDNA seq...
journal_title：Biochemical and biophysical research communications
pub_type： 杂志文章
doi：10.1016/0006-291x(88)90740-1
更新日期：1988-02-15 00:00:00
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journal_title：Biochemical and biophysical research communications
pub_type： 杂志文章
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journal_title：Biochemical and biophysical research communications
pub_type： 杂志文章
doi：10.1006/bbrc.1996.1361
更新日期：1996-09-13 00:00:00
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pub_type： 杂志文章
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journal_title：Biochemical and biophysical research communications
pub_type： 杂志文章
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journal_title：Biochemical and biophysical research communications
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journal_title：Biochemical and biophysical research communications
pub_type： 杂志文章
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更新日期：2002-03-08 00:00:00
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journal_title：Biochemical and biophysical research communications
pub_type： 杂志文章
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更新日期：1987-11-13 00:00:00
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pub_type： 杂志文章
doi：10.1016/0006-291x(90)92397-i
更新日期：1990-04-30 00:00:00
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journal_title：Biochemical and biophysical research communications
pub_type： 杂志文章
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更新日期：1988-06-30 00:00:00
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journal_title：Biochemical and biophysical research communications
pub_type： 杂志文章
doi：10.1016/s0006-291x(83)80170-3
更新日期：1983-09-15 00:00:00
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journal_title：Biochemical and biophysical research communications
pub_type： 杂志文章
doi：10.1016/j.bbrc.2016.07.108
更新日期：2016-09-16 00:00:00
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journal_title：Biochemical and biophysical research communications
pub_type： 杂志文章
doi：10.1006/bbrc.1996.0334
更新日期：1996-02-27 00:00:00
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journal_title：Biochemical and biophysical research communications
pub_type： 杂志文章
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更新日期：1990-04-16 00:00:00
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journal_title：Biochemical and biophysical research communications
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journal_title：Biochemical and biophysical research communications
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更新日期：1992-12-15 00:00:00
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journal_title：Biochemical and biophysical research communications
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更新日期：2005-10-07 00:00:00
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journal_title：Biochemical and biophysical research communications
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更新日期：2008-05-09 00:00:00
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journal_title：Biochemical and biophysical research communications
pub_type： 杂志文章
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更新日期：2012-03-23 00:00:00
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journal_title：Biochemical and biophysical research communications
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更新日期：2014-10-10 00:00:00
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journal_title：Biochemical and biophysical research communications
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更新日期：2006-07-07 00:00:00
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journal_title：Biochemical and biophysical research communications
pub_type： 杂志文章
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更新日期：2000-04-02 00:00:00
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journal_title：Biochemical and biophysical research communications
pub_type： 杂志文章
doi：10.1016/0006-291x(85)90988-x
更新日期：1985-10-15 00:00:00
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journal_title：Biochemical and biophysical research communications
pub_type： 杂志文章
doi：10.1006/bbrc.1994.1061
更新日期：1994-01-28 00:00:00
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journal_title：Biochemical and biophysical research communications
pub_type： 杂志文章
doi：10.1006/bbrc.1998.8541
更新日期：1998-04-28 00:00:00
