Abstract:
:The behavioral and EEG concomitants of kindling produced by daily electrical stimulation of the inferior colliculus have been recorded in three series of Wistar rats: (1) non epileptic controls (NE), (2) rats susceptible to audiogenic seizures (AS), (3) acoustically susceptible rats with prior kindling of audiogenic seizures by repeated sound exposure (KAS). Repeated collicular stimulation produced behavioral and EEG changes which were similar in the AS and the NE rats. The tonic seizure without cortical discharges elicited by the first stimulation progressively changed into tonic-clonic seizures with sustained cortical EEG discharges after more than 20 stimulations. In the KAS group, the electrical collicular kindling was clearly accelerated: kindled tonic-clonic seizures and their EEG discharges already occurred after one to five electrical stimulations. Similarly, after completion of electrical collicular kindling in AS, sound stimulations immediately induced characteristic kindled audiogenic seizures. The immediate reciprocal positive transfer observed between kindling of audiogenic seizures and kindling of seizures induced by electrical stimulation of the inferior colliculus suggests that kindling of these two brain-stem seizures involves similar structures and mechanisms.
journal_name
Epilepsy Resjournal_title
Epilepsy researchauthors
Hirsch E,Maton B,Vergnes M,Depaulis A,Marescaux Cdoi
10.1016/0920-1211(93)90093-msubject
Has Abstractpub_date
1993-06-01 00:00:00pages
133-9issue
2eissn
0920-1211issn
1872-6844pii
0920-1211(93)90093-Mjournal_volume
15pub_type
杂志文章abstract::Polyamine (tissue) concentrations have been studied in hippocampus and temporal neocortex from patients with temporal lobe epilepsy. Depth electrode recordings demonstrated hippocampal origin of the seizures, the temporal neocortex being involved during the discharge propagation. Neuropathological examination of excis...
journal_title:Epilepsy research
pub_type: 杂志文章
doi:10.1016/0920-1211(92)90035-r
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journal_title:Epilepsy research
pub_type: 杂志文章
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pub_type: 杂志文章,多中心研究
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journal_title:Epilepsy research
pub_type: 杂志文章
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journal_title:Epilepsy research
pub_type: 杂志文章
doi:10.1016/j.eplepsyres.2008.07.011
更新日期:2008-12-01 00:00:00
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journal_title:Epilepsy research
pub_type: 杂志文章
doi:10.1016/0920-1211(92)90057-z
更新日期:1992-12-01 00:00:00
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journal_title:Epilepsy research
pub_type: 杂志文章
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更新日期:2015-01-01 00:00:00
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journal_title:Epilepsy research
pub_type: 杂志文章
doi:10.1016/j.eplepsyres.2009.01.009
更新日期:2009-04-01 00:00:00
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pub_type: 杂志文章,meta分析,评审
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更新日期:2018-10-01 00:00:00
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journal_title:Epilepsy research
pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
doi:10.1016/s0920-1211(02)00071-2
更新日期:2002-06-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1016/j.eplepsyres.2014.09.003
更新日期:2014-11-01 00:00:00
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journal_title:Epilepsy research
pub_type: 杂志文章
doi:10.1016/j.eplepsyres.2016.07.003
更新日期:2016-10-01 00:00:00
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journal_title:Epilepsy research
pub_type: 杂志文章
doi:10.1016/j.eplepsyres.2012.02.001
更新日期:2012-06-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章,多中心研究
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doi:10.1016/j.eplepsyres.2012.09.011
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pub_type: 杂志文章
doi:10.1016/j.eplepsyres.2010.07.014
更新日期:2010-10-01 00:00:00
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journal_title:Epilepsy research
pub_type: 临床试验,杂志文章
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更新日期:1998-07-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.eplepsyres.2011.05.015
更新日期:2011-09-01 00:00:00
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journal_title:Epilepsy research
pub_type: 杂志文章
doi:10.1016/0920-1211(95)00003-s
更新日期:1995-05-01 00:00:00
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journal_title:Epilepsy research
pub_type: 杂志文章
doi:10.1016/j.eplepsyres.2016.11.006
更新日期:2017-01-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2006-01-01 00:00:00
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journal_title:Epilepsy research
pub_type: 杂志文章
doi:10.1016/j.eplepsyres.2015.09.006
更新日期:2015-11-01 00:00:00
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journal_title:Epilepsy research
pub_type: 杂志文章
doi:10.1016/j.eplepsyres.2015.06.001
更新日期:2015-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.eplepsyres.2011.08.012
更新日期:2012-01-01 00:00:00