Pathogenesis of Schistosoma mansoni infection.

abstract：:Sm8 is a major tegumental antigen of Schistosoma mansoni. The partial cDNA was isolated and analyzed. Sequence analysis revealed transmembrane compatible hydrophobic domains and a putative leucine zipper pattern. The mRNA and the protein are predominantly expressed in adult worms. ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Abath FG,Xavier EM,Montenegro SM,Werkhauser RP

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Gene reporter-fluorescent cells have emerged as alternative method for drug screening. OBJECTIVE:Achievement of constitutive expression of fluorescent protein GFP by Leishmania braziliensis as alternative method for drug screening. METHODS:L. braziliensis-GFP was generated using Leishmania tarentolae pLEXS...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Bastos MS,Souza LÂ,Onofre TS,Silva A Júnior,Almeida MR,Bressan GC,Fietto JL

更新日期：2017-02-01 00:00:00

abstract：:We describe a technique to separate male and female pupae of sand flies. This has reduced the labour to separate flies after emergence and also allows the isolation of unmated adults for behavioural and physiological studies. ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Brazil BG,Brazil RP

更新日期：2000-07-01 00:00:00

abstract：:Leishmania braziliensis is the etiological agent of American mucosal leishmaniasis, one of the most severe clinical forms of leishmaniasis. Here, we report the assembly of the L. braziliensis (M2904) genome into 35 continuous chromosomes. Also, the annotation of 8395 genes is provided. The public availability of this ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： González-de la Fuente S,Camacho E,Peiró-Pastor R,Rastrojo A,Carrasco-Ramiro F,Aguado B,Requena JM

更新日期：2018-12-10 00:00:00

abstract：:This report describes the development of a SYBR Green I based real time polymerase chain reaction (PCR) protocol for detection on the ABI Prism 7000 instrument. Primers targeting the gene encoding the SSU rRNA were designed to amplify with high specificity DNA from Schistosoma mansoni, in a real time quantitative PCR ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Gomes AL,Melo FL,Werkhauser RP,Abath FG

更新日期：2006-09-01 00:00:00

abstract：:The extent of genomic variability of clones of Schistosoma mansoni obtained from field isolates was compared with that of strains that have been laboratory maintained. Analysis was undertaken using randomly amplified polymorphic DNAs (RAPDs) generated with three primers. Phenograms showing the similarity among the clo...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Pinto PM,Brito CF,Passos LK,Tendler M,Simpson AJ

更新日期：1997-05-01 00:00:00

abstract：:This was a retrospective descriptive study on a series of cases of schistosomal myeloradiculopathy (SMR) and the aim was to investigate the incidence of this disease and its clinical and epidemiological characteristics in cases diagnosed at three healthcare units in Pernambuco, Brazil between 1994-2006. The data were ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Araújo KC,Silva Cda R,Santos AG,Barbosa CS,Ferrari TC

更新日期：2010-07-01 00:00:00

abstract：:We analyzed prospectively 326 laboratory-confirmed, uncomplicated malarial infections (46.3% due to Plasmodium vivax, 35.3% due to P. falciparum, and 18.4% mixed-species infections) diagnosed in 162 rural Amazonians aged 5-73 years. Thirteen symptoms (fever, chills, sweating, headache, myalgia, arthralgia, abdominal p...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： da Silva-Nunes M,Ferreira MU

更新日期：2007-06-01 00:00:00

abstract：:An overview is presented of the results obtained with biodegradable sustained release devices (SRDs) containing a mixture of polymers and either isometamidium (ISMM) or ethidium. Under controlled laboratory conditions (monthly challenge with tsetse flies infected with Trypanosoma congolense) the protection period in S...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Geerts S,Brandt J,De Deken R

更新日期：1999-03-01 00:00:00

abstract：:Acinetobacter baumannii is a strictly aerobic bacterium which causes severe infections, however its pathogenic characteristics are not well defined. Thirteen A. baumannii strains isolated from urine of hospitalized and nonhospitalized patients with different ages were investigated for the presence of virulence factors...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Braun G,Vidotto MC

更新日期：2004-12-01 00:00:00

abstract：:A study of crepuscular and night-biting mosquitoes was conducted at remote settlements along the Padauiri River, middle Negro River, state of Amazonas, Brazil. Collections were performed with human bait and a CDC-light trap on three consecutive days per month from June 2003-May 2004. In total, 1,203 h of collection we...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Suárez-Mutis MC,Fé NF,Alecrim W,Coura JR

更新日期：2009-02-01 00:00:00

abstract：:Several parasitological studies carried out in El Salvador between 2000-2012 showed a higher frequency of acute cases of Chagas disease than that in other Central American countries. There is an urgent need for improved Chagas disease surveillance and vector control programs in the provinces where acute Chagas disease...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Sasagawa E,Aguilar AV,Ramírez MA,Chévez JE,Nakagawa J,Cedillos RA,Kita K

更新日期：2014-04-01 00:00:00

abstract：:From 1970 to 1982, 884 cases of human leptospirosis were serologically diagnosed at the Leptospirosis Laboratory, Fundação Oswaldo Cruz - FIOCRUZ, by means of the microscopic agglutination test. Of these patients, 775 were hospitalized in the city of Rio de Janeiro, and 109 were reported by other Brazilian cities. Ict...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Andrade J,Brandão AP

更新日期：1987-01-01 00:00:00

abstract：:Sandfly prevalence in the Kani tribe settlements of Western Ghats in India was investigated. A total of 1,279 sandflies comprising 17 species was obtained. Sandfly abundance showed a negative correlation (r = -0.97, p = 0.003) with increase in altitudinal ranges from 0-1,000 m. When sandfly samples were grouped accord...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ranganathan S,Swaminathan S

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Since the early 1990s, programs to control Chagas disease in South America have focused on eradicating domiciliary Triatoma infestans, the main vector. Seroprevalence studies of the chagasic infection are included as part of the vector control programs; they are essential to assess the impact of vector contr...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Russomando G,Cousiño B,Sanchez Z,Franco LX,Nara EM,Chena L,Martínez M,Galeano ME,Benitez L

更新日期：2017-05-01 00:00:00

abstract：:Studies on natural infection by Leishmania spp of sandflies collected in endemic and nonendemic areas can provide important information on the distribution and intensity of the transmission of these parasites. This study sought to investigate the natural infection by Leishmaniain wild female sandflies. The specimens w...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Oliveira EF,Casaril AE,Mateus NL,Murat PG,Fernandes WS,Oshiro ET,Oliveira AG,Galati EA

更新日期：2015-12-01 00:00:00

abstract：:The direct agglutination test (DAT) based on a freeze-dried antigen and the rK39 dipstick test were evaluated for the sero-diagnosis of visceral leishmaniasis (VL). The sensitivity and specificity of both tests were determined using sera from confirmed VL patients (n = 21), healthy controls (n = 19) and from patients ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Schallig HD,Canto-Cavalheiro M,da Silva ES

更新日期：2002-10-01 00:00:00

abstract：:Aspects related to hatching, lifetime, number of blood meals for molting, mortality, feeding time, and postfeeding defecation delay were evaluated and compared in each instar of three North American Triatominae: Triatoma gerstaeckeri, Triatoma lecticularia and Triatoma protracta, all of them fed on rabbits. No signifi...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Martínez-Ibarra JA,Alejandre-Aguilar R,Paredes-González E,Martínez-Silva MA,Solorio-Cibrián M,Nogueda-Torres B,Trujillo-Contreras F,Novelo-López M

更新日期：2007-12-01 00:00:00

abstract：:In the present paper, we developed a primary culture of Rhodnius prolixus salivary gland and main salivary canal cells. Cells remained viable in culture for 30 days. Three types of cells were indentified in the salivary gland cultures, with binuclear cells being the most abundant. The supernatants of salivary cultures...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Rocha FF,Araujo RN,Silva LM,Gontijo NF,Pereira MH

更新日期：2010-03-01 00:00:00

abstract：:This paper examines the distribution and infection of Biomphalaria glabrata with Schistosoma mansoni in all aquatic snail habitats in a rural area in the state of Minas Gerais, Brazil, in relation to physico/biotic and behavioral factors. Snail and environmental surveys were carried out semi-annually between July 2001...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Kloos H,Passos LK,Loverde P,Oliveira RC,Gazzinelli A

更新日期：2004-11-01 00:00:00

abstract：:For the first time, a jar of embalming rejects was studied in search for helminth parasite eggs. This kind of jar was used to put discarded material by Egyptian embalmers during mummification process. Ascaris lumbricoides and Taenia saginata eggs were found in the linen and strip fragment contents of the jar, dated of...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Harter S,Le Bailly M,Janot F,Bouchet F

更新日期：2003-01-01 00:00:00

abstract：:Sequences of the cytochrome c oxidase subunit I (COI) mitochondrial gene from adults of 22 Culex (Culex) species from Argentina and Brazil were employed to assess species identification and to test the usefulness of COI for barcoding using the best close match (BCM) algorithm. A pairwise Kimura two-parameter distance ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Laurito M,Oliveira TM,Almirón WR,Sallum MA

更新日期：2013-01-01 00:00:00

abstract：:Cytokines are important in the cell-mediated response to Schistosoma mansoni eggs. We have found that Th2 cytokine responses (e.g. IL-4 and IL-5) are augmented after egg laying begins while Th1 responses (IL-2 and IFN-gamma) are down regulated in S. mansoni infected mice. Treatment of mice with anti-IL-5 monoclonal an...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cheever AW,Xu Y,Macedonia JG,Cox T,Hieny S,Sher A

更新日期：1992-01-01 00:00:00

abstract：:Sand flies were collected in the central region of the state of Rondônia (W 64 degrees 30' to 63 degrees 00' and S 10 degrees 00'to 11 degrees 00') using Shannon and CDC light traps from October 1997 to August 2000. A total of 85,850 specimens representing 78 named species were captured. Of these 14 were new records f...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Gil LH,Basano SA,Souza AA,Silva MG,Barata I,Ishikawa EA,Camargo LM,Shaw JJ

更新日期：2003-09-01 00:00:00

abstract：:The Kilombero Malaria Project (KMP) attempts to define operationally useful indicators of levels of transmission and disease and health system relevant monitoring indicators to evaluate the impact of disease control at the community or health facility level. The KMP is a longitudinal community based study (N = 1024) i...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Teuscher T

更新日期：1992-01-01 00:00:00

abstract：:Biomphalaria glabrata can react through different pathways to Schistosoma mansoni miracidium penetration, according to the degree of resistance/susceptibility presented by different snail strains, which is a genetically determined character, resistance being the dominant feature. However, it has been observed that pre...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Azevedo CM,Borges CC,Andrade ZA

更新日期：2006-09-01 00:00:00

abstract：:Epstein-Barr virus (EBV) plays a major role in liver pathology. Similar to other members of the herpesvirus family, EBV establishes a persistent infection in more than 90% of adults. The aim of this study was to evaluate the impact of EBV and chronic hepatitis C co-infection (HCV) on biochemical and immunological resp...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Shoman S,Nabil M,Tabl A,Ghanem H,Kafrawy SE

更新日期：2014-09-01 00:00:00

abstract：:Mosquito-borne diseases such as dengue fever, chikungunya or malaria affect millions of people each year and control solutions are urgently needed. An international research program is currently being developed that relies on the introduction of the bacterial endosymbiont Wolbachia pipientis into Aedes aegypti to cont...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Popovici J,Moreira LA,Poinsignon A,Iturbe-Ormaetxe I,McNaughton D,O'Neill SL

更新日期：2010-12-01 00:00:00

abstract：:A new species of Brazilian phlebotomine sandfly found in Brazil, municipality of Diamantina, state of Minas Gerais, is described based on males and females collected in a quartzite cave. The body of spermathecae is continuous to the individual duct, lanky and tapering at the end, with conical shaped, not striated and ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Barata RA,Serra e Meira PC,Carvalho GM

更新日期：2012-12-01 00:00:00

abstract：:Since the emergence of West Nile virus (WNV) in North America in 1999, there have been several reports of WNV activity in Central and South American countries. To detect WNV in Brazil, we performed a serological survey of horses from different regions of Brazil using recombinant peptides from domain III of WNV. Positi...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Silva JR,Medeiros LC,Reis VP,Chavez JH,Munhoz TD,Borges GP,Soares OA,Campos CH,Machado RZ,Baldani CD,Silva ML,Faria JL,Silva EE,Figueiredo LT

更新日期：2013-11-01 00:00:00