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Purification and characterization of a novel tetradecapeptide that modulates oesophagus motility in Lymnaea stagnalis.

Abstract：

:The isolated oesophagus of Lymnaea stagnalis was used as a bioassay preparation to identify peptides that modulate the activity of the oesophagus. Several modulatory messengers were detected from the oesophageal extract. One of these, having an excitatory action, was further purified from both the oesophagus and the central nervous system through high performance gel permeation chromatography followed by serial reversed phase high performance liquid chromatography. The purified peptide was chemically characterized through amino acid sequencing and mass spectrometry as GFRANSASRVAHGY-NH2.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Li KW,Holling T,de With ND,Geraerts WP

doi

10.1006/bbrc.1993.2585

subject

Has Abstract

pub_date

1993-12-30 00:00:00

pages

1056-61

issue

3

eissn

0006-291X

issn

1090-2104

pii

S0006291X83725854

journal_volume

197

pub_type

杂志文章

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