Disease clusters, exact distributions of maxima, and P-values.

Abstract:

:This paper presents combinatorial (exact) methods that are useful in the analysis of disease cluster data obtained from small environments, such as buildings and neighbourhoods. Maxwell-Boltzmann and Fermi-Dirac occupancy models are compared in terms of appropriateness of representation of disease incidence patterns (space and/or time) in these environments. The methods are illustrated by a statistical analysis of the incidence pattern of bone fractures in a setting wherein fracture clustering was alleged to be occurring. One of the methodological results derived in this paper is the exact distribution of the maximum cell frequency in occupancy models.

journal_name

Stat Med

journal_title

Statistics in medicine

authors

Grimson RC

doi

10.1002/sim.4780121906

subject

Has Abstract

pub_date

1993-10-01 00:00:00

pages

1773-94

issue

19-20

eissn

0277-6715

issn

1097-0258

journal_volume

12

pub_type

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