Abstract:
:Computed tomography was used to compare the following three groups: obsessive-compulsive disorder (OCD) patients with high scores on a soft neurological sign examination, OCD patients with low soft neurological sign scores, and control subjects. Neuranatomical structures were measured using quantitative volumetric analysis. OCD patients with high soft sign scores had significantly increased ventricular volumes compared with OCD patients with low soft sign scores and control subjects. Caudate and lenticular nucleus volumes did not differ between groups.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Stein DJ,Hollander E,Chan S,DeCaria CM,Hilal S,Liebowitz MR,Klein DFdoi
10.1016/0925-4927(93)90026-esubject
Has Abstractpub_date
1993-10-01 00:00:00pages
143-50issue
3eissn
0165-1781issn
1872-7123pii
0165-1781(93)80009-Tjournal_volume
50pub_type
杂志文章abstract::Moclobemide is a reversible, short-acting monoamine oxidase inhibitor (MAO1), specific for MAO A. To study moclobemide effects on the tyramine pressor response, we gave 12 depressed patients (2 males, 10 females; mean age 47, SD 11 years) an i.v. tyramine test after 7 days drug free. The mean (+/- SD) tyramine dose to...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(87)90036-9
更新日期:1987-11-01 00:00:00
abstract::Treatment of bipolar disorder often results in patients taking several drugs in an attempt to alleviate residual depressive symptoms, which can lead to an accumulation of side effects. New treatments for bipolar depression that do not increase the side effect burden are needed. One nonpharmacological treatment with fe...
journal_title:Psychiatry research
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.psychres.2012.01.015
更新日期:2012-03-30 00:00:00
abstract::The minority of people who have experienced a traumatic event and were diagnosed as either suffering from PTSD or from Adjustment disorder, may suggest that victims of a traumatic event vary in risk factors for the disorders. The current research aimed at examining the association between reports of Adjustment disorde...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.08.085
更新日期:2017-12-01 00:00:00
abstract::This study compared basal concentrations of plasma beta-endorphin/beta-lipotropin-like immunoreactivity and dexamethasone suppression of cortisol in seven chronic pain patients, seven psychiatric disorder patients, and seven normal volunteers. Pain patients and psychiatric patients showed significantly higher basal co...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(83)90005-7
更新日期:1983-08-01 00:00:00
abstract::Neurological soft signs and neurocognitive impairments are commonly observed in first episode psychosis but the correlation of these factors remains controversial. Here, we evaluated 30 patients with remitted first episode psychosis and 30 healthy controls for the presence and severity of neurological soft signs (usin...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.07.044
更新日期:2014-12-15 00:00:00
abstract::The goal of this study was to assess integrity of the cingulum bundle in patients diagnosed with first episode schizophrenia, chronic schizophrenia, and matched controls as well as to determine the relationship between diffusion measures of cingulum bundle integrity and severity of patients' delusions of reference. Pa...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2014.08.002
更新日期:2014-11-30 00:00:00
abstract::Higher electromyographic (EMG) activity levels of corrugator and zygomatic face muscles have been reported to be pretreatment predictors of better clinical outcome in depressed patients. We tested this possibility in 29 drug-free, rigorously diagnosed subjects by measuring low-level EMG activity of corrugator and zygo...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(84)90082-9
更新日期:1984-12-01 00:00:00
abstract::The purpose of this study was to determine levels of Distress Tolerance (DT) and to compare levels of DT, depression, and anxiety in the parents of substance dependent patients. This sample included 40 parents of inpatients undergoing treatment for substance dependence (SDPP) in the Balıklı Rum Hospital, Istanbul, Tur...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.12.026
更新日期:2017-05-01 00:00:00
abstract::The prevailing nosological classification of body dysmorphic disorder (BDD) encompasses an optional specifier "with absent insight/delusional beliefs" for patients who hold high conviction of the veracity of their disorder-specific beliefs. Yet limited research has examined the explicit nature of delusional beliefs in...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2019.112694
更新日期:2020-02-01 00:00:00
abstract::Cognitive deficits have been found to be more prevalent in psychotic than in other disorders. Longitudinal research has shown that these deficits were generally already existent before onset of illness and are therefore not necessarily attributable to neurodegenerative processes. This study investigated whether both l...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2013.05.035
更新日期:2013-11-30 00:00:00
abstract::The human opposite paired-containing (HOPA) gene is believed to be a co-activator of the thyroid hormone receptor and involved in thyroid hormone signal transduction. The gene consists of 45 exons and includes a dodecamer duplication in exon 43, which has been reported to be associated with mental retardation, autism,...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(03)00135-5
更新日期:2003-07-15 00:00:00
abstract::This school-based study aimed to investigate the prevalence of being at risk for depression, bullying behavior, and current smoking among Chinese adolescents in order to explore gender differences in the vulnerability of adolescents with these behaviors to develop a smoking habit. A total of 35,893 high school student...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.01.027
更新日期:2016-03-30 00:00:00
abstract::Previous work suggests that iomazenil (formerly known as Ro 16-0154) is a useful ligand for static imaging of the benzodiazepine (BZ) receptor with single photon emission computed tomography (SPECT). The present study evaluated the feasibility of dynamic SPECT imaging of cerebral radioactivity following intravenous [1...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0925-4927(92)90001-k
更新日期:1992-08-01 00:00:00
abstract::Exposure to traumatic events during childhood is associated with an elevated risk of adult obesity. It has been hypothesized that the psychological sequelae from childhood trauma account for this risk, though no study has examined whether an increased risk of obesity is found in persons without psychological disorders...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2005.11.007
更新日期:2006-05-30 00:00:00
abstract::Cannabis use has been associated with a continuum of psychotic experiences. However, it is unclear whether mood and anxiety symptoms account for increases in attenuated positive psychotic symptoms (APPS) among cannabis users. We predicted that depression and anxiety symptoms would mediate the relation between cannabis...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.03.040
更新日期:2014-08-15 00:00:00
abstract::Normal brain activity is associated with task-related pH changes. Although central nervous system syndromes associated with significant acidosis and alkalosis are well understood, the effects of less dramatic and chronic changes in brain pH are uncertain. One environmental factor known to alter brain pH is the extreme...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2014.04.002
更新日期:2014-06-30 00:00:00
abstract::Twenty-one unmedicated, sequentially admitted psychiatric patients of either sex and four male healthy volunteers were given an intravenous injection of 2.5 mg morphine. Blood samples were drawn immediately before and at 30-minute intervals for 3 hours after the injection and assayed for cortisol. Morphine suppressed ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(85)90044-7
更新日期:1985-06-01 00:00:00
abstract::Impulse Control Disorders (ICDs) are a set of behaviours characterised by impulsivity despite known harm. Related to ICDs is the dopamine dysregulation syndrome (DDS), which is characterised by an addiction-like consumption of dopaminergic medication and punding. These behaviours all have an increased prevalence in Pa...
journal_title:Psychiatry research
pub_type: 杂志文章,评审
doi:10.1016/j.psychres.2014.12.005
更新日期:2015-02-28 00:00:00
abstract:BACKGROUND:This study aims to establish if adult patients with major depressive disorder (MDD) and childhood Attention Deficit/Hyperactivity disorder (ADHD) symptoms would be more frequently within the bipolar spectrum than depressed patients without childhood ADHD. METHODS:This study was carried out in outpatients re...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.12.055
更新日期:2017-03-01 00:00:00
abstract::Clinical and biochemical findings link anorexia nervosa (AN) and primary effective disorders (PAD). Clonidine, an alpha 2-adrenoceptor agonist, has been shown to blunt growth hormone (GH) response and greatly lower plasma cortisol in PAD patients. We examined the GH, cortisol, and beta-endorphin (beta-EP) responses to...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(87)90120-x
更新日期:1987-01-01 00:00:00
abstract::Left temporoparietal repetitive transcranial magnetic stimulation (rTMS) reportedly diminishes verbal hallucinations. A 21-year-old schizophrenic man, who had killed his mother in the belief that she was a demon, failed to respond to combined treatment with a variety of antipsychotic agents. His persistent hallucinati...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(03)00148-3
更新日期:2003-08-30 00:00:00
abstract::We used functional magnetic resonance imaging (fMRI) to investigate dysfunction in the amygdala and orbitofrontal cortex in adolescents with disruptive behavior disorders and psychopathic traits during a moral judgment task. Fourteen adolescents with psychopathic traits and 14 healthy controls were assessed using fMRI...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2011.07.008
更新日期:2011-12-30 00:00:00
abstract::Serum prolactin levels were monitored for 2 hours after injection of chlorpromazine (CPZ) 50 mg intramuscularly (i.m.) in 6 male normal controls and 14 newly admitted male chronic schizophrenics. The increase in serum prolactin levels in the male normal controls was not significantly different from that in patients. S...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(81)90065-2
更新日期:1981-08-01 00:00:00
abstract::Choline chloride (2g q.i.d.) and placebo were admin stered to nine young adults in a placebo-drug-placebo design. Subjects took memory tests at the end of both placebo periods and at the end of the choline period. All nine subjects had participated in a previous study in which 1.0 mg of physostigmine infused over a 1-...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(80)90071-2
更新日期:1980-05-01 00:00:00
abstract::Although a strong association between alexithymia and somatization has been postulated in numerous studies, no systematic study has investigated the psychometric properties of the 20-item Toronto Alexithymia Scale (TAS-20) in a sample of patients with somatoform disorder yet. The purpose of this study was to ensure a ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.12.013
更新日期:2015-02-28 00:00:00
abstract::In schizophrenia patients reduced cerebral asymmetry is an important finding and this may reflect a disturbance in cortical development. We investigated planum temporale (PT) volume and asymmetry in 23 first-episode schizophrenia patients compared to healthy controls and found for the first time an in vivo volume asym...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2011.02.008
更新日期:2011-07-30 00:00:00
abstract::Previous studies on the factorial structure of the Patient Health Questionnaire (PHQ-9) have yielded divergent results, and there is no consensus on which factorial structure provides a more adequate fit. In Colombia, no precise method to estimate the factorial structure of the PHQ-9 has been used. The purpose of this...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.08.071
更新日期:2018-11-01 00:00:00
abstract::In order to investigate electroencephalographic (EEG) biomarkers of auditory processing for schizophrenia, we studied a group with a well known high-risk profile: patients with 22q11.2 deletion syndrome (22q11 DS) have a 30% risk of developing schizophrenia during adulthood. We performed high-density EEG source imagin...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2012.09.002
更新日期:2013-05-30 00:00:00
abstract::This study identified empirically derived subtypes of gamblers based on the Diagnostic and Statistical Manual of Mental Disorders-IV (DSM-IV) diagnostic criteria for pathological gambling disorder (PGD). Data from the gamblers (n=5644) who participated in the 2007 British Gambling Prevalence Survey (BGPS) were analyse...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2009.11.010
更新日期:2010-07-30 00:00:00
abstract::Neuroimaging in anorexia nervosa has revealed morphological and functional alterations, most of which are currently interpreted as consequences of the anorectic state that are reversible, at least partially, after weight gain. Enlargement of CSF spaces, mainly of cortical sulci, is evident on CT and MRI. This reversib...
journal_title:Psychiatry research
pub_type: 杂志文章,评审
doi:10.1016/0165-1781(96)02990-3
更新日期:1996-04-16 00:00:00