Abstract:
:Concepts of eating disorders have altered so that anorexia nervosa is now recognized as an important but uncommon syndrome within a spectrum of disordered eating. Behaviours used by dieters constitute the mild end of the eating disorder spectrum. Dieting in young women is for the most part a transient and benign activity without longer-term consequences. However, a group of dieters do progress to develop the symptoms and behaviour of eating disorders, so that dieting has been associated with an eight-fold rise in the risk of later eating disorder. Dieting or factors closely associated may account for most eating disorders in young women. Many antecedents of eating disorder appear to operate through increasing the risk of dieting rather than determining eating disorders specifically. Only the development of further neurotic and depressive symptoms characterizes dieters progressing to eating disorders. As the evidence implicating dieting in the origin of eating disorders becomes stronger so strategies for primary prevention become clearer.
journal_name
Ann Medjournal_title
Annals of medicineauthors
Patton GCdoi
10.3109/07853899209149955subject
Has Abstractpub_date
1992-08-01 00:00:00pages
281-5issue
4eissn
0785-3890issn
1365-2060journal_volume
24pub_type
杂志文章,评审abstract::MicroRNAs are small non-coding RNAs that bind to multiple target mRNAs to control gene expression post-transcriptionally by inhibiting translation. In mammalian cells, microRNAs play important roles in a diverse array of cellular processes (e.g. cell proliferation and differentiation). However, alterations in their le...
journal_title:Annals of medicine
pub_type: 杂志文章,评审
doi:10.3109/07853890.2014.958196
更新日期:2014-12-01 00:00:00
abstract::A 33-year old man suddenly dropped dead during a military march. He had complained of non-specific thoracoabdominal symptoms, pain and fatigue for a year before his death. Autopsy showed coronary polyarteritis nodosa of the left main coronary artery. This patient seems to be only the second case with isolated polyarte...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.3109/07853899009147262
更新日期:1990-06-01 00:00:00
abstract::Caveolae are vesicular organelles (50-100-nm in diameter) that are particularly abundant in cells of the cardiovascular system, including endothelial cells, smooth muscle cells, macrophages, cardiac myocytes and fibroblasts. In these cell types, caveolae function both in protein trafficking and signal transduction, as...
journal_title:Annals of medicine
pub_type: 杂志文章,评审
doi:10.1080/07853890410018899
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:The association between otitis media and vestibular symptoms has been hypothesized in the past. Thus, in this study, we aimed to critically analyze (based in a systematic review of the literature) whether patients who have otitis media are at greater risk of developing vestibular impairment or not. METHODS:...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.1080/07853890.2018.1470665
更新日期:2018-08-01 00:00:00
abstract::Study of the growth and development of cartilage and bone has been difficult because the structure of the tissues makes biological experiments hard to conduct. Recent advances in molecular biology have offered new possibilities for studying these processes. Many cartilage and bone specific cDNAs have been cloned and c...
journal_title:Annals of medicine
pub_type: 杂志文章,评审
doi:10.3109/07853899109148050
更新日期:1991-08-01 00:00:00
abstract:PURPOSE:Evidence on the association between depression, antidepressant use and venous thromboembolism (VTE) risk is conflicting. We conducted a systematic review and meta-analysis of published observational studies evaluating the associations of depression and antidepressant use with VTE risk. DESIGN:Eligible studies ...
journal_title:Annals of medicine
pub_type: 杂志文章,meta分析
doi:10.1080/07853890.2018.1500703
更新日期:2018-09-01 00:00:00
abstract::We evaluated the reliability hospital discharge register data in the assessment of acute myocardial infarction trends. In the FINMONICA study areas, trends in age standarized attack rates for the years 1983-90 were calculated independently from two sources: the nationwide Finnish hospital discharge register and the FI...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.3109/07853899509002467
更新日期:1995-10-01 00:00:00
abstract::Insulin resistance in humans is not always accompanied by obesity, since severe insulin resistance also characterizes patients lacking subcutaneous fat such as those with HAART- (highly-active antiretroviral therapy)-associated lipodystrophy. Both obese and lipodystrophic patients, however, have an increase in the amo...
journal_title:Annals of medicine
pub_type: 杂志文章,评审
doi:10.1080/07853890510037383
更新日期:2005-01-01 00:00:00
abstract::Immunocytochemical studies using antibodies to cytoskeletal proteins have provided conflicting data on the components of paired helical filaments (PHF), due solely to immunological cross-reactivities. To avoid such ambiguity, we developed a protein chemical approach to the identification of the PHF components. After t...
journal_title:Annals of medicine
pub_type: 杂志文章,评审
doi:10.3109/07853898909149198
更新日期:1989-01-01 00:00:00
abstract:AIM:Previous studies have shown that both triglyceride glucose (TyG) and haemoglobin glycation indexes (HGI) are predictors of cardiovascular risk. However, the prognostic value of TyG index and HGI in patients with type 2 diabetes mellitus (T2DM) and stable coronary artery disease (CAD) is not determined. METHODS:We ...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.1080/07853890.2018.1523549
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND AIMS:A mild increase in liver enzyme levels is sometimes observed in patients with diabetic ketosis or ketoacidosis. The aim of the present study was to assess the cause and prevalence of the elevation of liver transaminase levels in fulminant and acute-onset type 1 diabetic patients experiencing diabetic ke...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.1080/07853890802032711
更新日期:2008-01-01 00:00:00
abstract::Susceptibility to insulin-dependent diabetes mellitus (IDDM) correlates with the absence of aspartic acid in position 57 of the DQB1 and/or the presence of arginine in position 52 of the DQA1. It has been postulated that transcomplementation between the DQ alpha and beta chains of the two haplotypes could create new m...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.3109/07853899209167007
更新日期:1992-12-01 00:00:00
abstract::Clinical know-how and skills as well as up-to-date scientific evidence are cornerstones for providing effective treatment for patients. However, in order to improve the effectiveness of treatment in ordinary practice, also appropriate documentation of care at the health care units and benchmarking based on this docume...
journal_title:Annals of medicine
pub_type: 社论
doi:10.3109/07853890.2011.653394
更新日期:2013-03-01 00:00:00
abstract::Due to its varied and variable phenotypes, Andersen-Tawil syndrome (ATS) holds a unique place in the field of channelopathies. Patients with ATS typically present with the triad of periodic paralysis, cardiac arrhythmias, and developmental dysmorphisms. Although penetrance of ATS is high, disease expression and severi...
journal_title:Annals of medicine
pub_type: 杂志文章,评审
doi:10.1080/17431380410032490
更新日期:2004-01-01 00:00:00
abstract::Troglitazone is a novel once-daily oral antidiabetic agent for the treatment of type 2 diabetes patients. Here, we report the overall dose response characteristics of troglitazone, with respect to effects on metabolic control, using a pharmacodynamic model. Data from week 12 from two previously reported double-blind, ...
journal_title:Annals of medicine
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.3109/07853899808999405
更新日期:1998-04-01 00:00:00
abstract::The mucosal surfaces are the first portals of entry for most infectious agents, among which respiratory and intestinal viruses are of greatest epidemiological importance. To combat these infections, the immune system uses unspecific and specific mechanisms. Unspecific responses include the production of virus-induced ...
journal_title:Annals of medicine
pub_type: 杂志文章,评审
doi:10.3109/07853890109002074
更新日期:2001-04-01 00:00:00
abstract:INTRODUCTION:As individuals age, the prevalence of neurocognitive and mental health disorders increases. Current biomedical treatments do not completely address the management of these conditions. Despite new pharmacological therapy the challenges of managing these diseases remain.There is increasing evidence that the ...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.1080/07853890.2020.1808239
更新日期:2020-12-01 00:00:00
abstract::Hypertrophic cardiomyopathy (HCM) is phenotypically and genotypically a heterogeneous disease. Since 1989, four chromosomal loci have been identified for HCM and the genes residing on three of these have been identified as beta-myosin heavy chain (beta-MHC), cardiac troponin-T and alpha-tropomyosin. These genes code f...
journal_title:Annals of medicine
pub_type: 杂志文章,评审
doi:10.3109/07853899509002583
更新日期:1995-06-01 00:00:00
abstract::The metabolic syndrome, which is very common in the general population, is defined by the clustering of several classic cardiovascular risk factors, such as type 2 diabetes, hypertension, high triglycerides and low high-density lipoprotein cholesterol (HDL). Central obesity and insulin resistance, which are the two un...
journal_title:Annals of medicine
pub_type: 杂志文章,评审
doi:10.1080/07853890500401234
更新日期:2006-01-01 00:00:00
abstract::On average, 15,000 cases of measles occurred annually in Finland before the initiation of a vaccination programme in 1975. Because of insufficient activity, the vaccination coverage failed to reach the required level of over 90%, and cases continued to occur. The policy was revolutionized in 1982 by launching a projec...
journal_title:Annals of medicine
pub_type: 社论
doi:10.3109/07853899808999395
更新日期:1998-04-01 00:00:00
abstract::Vaccines are considered to be one of the greatest public health achievements of the last century. Depending on the biology of the infection, the disease to be prevented, and the targeted population, a vaccine may require the induction of different adaptive immune mechanisms to be effective. Understanding the basic con...
journal_title:Annals of medicine
pub_type: 杂志文章,评审
doi:10.1080/07853890.2017.1407035
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:Hyperglycaemia has emerged as an important risk factor for death in coronavirus disease 2019 (COVID-19). The aim of this study was to evaluate the association between blood glucose (BG) levels and in-hospital mortality in non-critically patients hospitalized with COVID-19. METHODS:This is a retrospective mu...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.1080/07853890.2020.1836566
更新日期:2021-12-01 00:00:00
abstract::Statins are the first-line choice in Lipid-lowering therapy to reduce cardiovascular risk. In a continuous attempt to optimise treatment success, there is a need for additional research on genes and related molecular pathways that can determine the efficacy and toxicity of lipid-lowering drugs. Several variations with...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.1080/07853890.2020.1800074
更新日期:2020-12-01 00:00:00
abstract::Sleep and wakefulness are complex behaviors that are influenced by many genetic and environmental factors, which are beginning to be discovered. The contribution of genetic components to sleep disorders is also increasingly recognized as important. Point mutations in the prion protein, period 2, and the prepro-hypocre...
journal_title:Annals of medicine
pub_type: 杂志文章,评审
doi:10.1080/07853890500372047
更新日期:2005-01-01 00:00:00
abstract::Molecular oxygen (O2)is a basic requirement for cellular growth and viability and many aspects of anatomy and physiology are dedicated to achieving reliable distribution. Recent work has identified a specific sensing and response system, centred around a transcription complex called Hypoxia-inducible Factor 1 (HIF-1),...
journal_title:Annals of medicine
pub_type: 杂志文章,评审
doi:10.1080/0785389031000458233
更新日期:2003-01-01 00:00:00
abstract::On theoretical grounds, an apo E receptor defect should be manifested by the accumulation of lipoprotein remnants that are normally cleared by this receptor and cannot be processed by the normal apo B, E receptor (LDL-receptor). Furthermore, the defect should not be selective for a specific apo E phenotype since none ...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.3109/07853899109148042
更新日期:1991-04-01 00:00:00
abstract::More than 50 different pharmacological and mechanical interventions have been tested to date for prevention of vascular restenosis without success. Intracoronary radiotherapy is the first one showing promise of significantly attenuating neointimal proliferation, causing positive vascular remodelling and thus inhibitin...
journal_title:Annals of medicine
pub_type: 杂志文章,评审
doi:10.3109/07853890009002033
更新日期:2000-12-01 00:00:00
abstract::Idiopathic pulmonary fibrosis (IPF) is the most common and lethal form of idiopathic interstitial pneumonia. The disease, which occurs primarily in middle-aged and older adults, is thought to arise following an aberrant reparative response to alveolar epithelial cell injury characterized by secretion of excessive amou...
journal_title:Annals of medicine
pub_type: 杂志文章,评审
doi:10.3109/07853890.2014.982165
更新日期:2015-02-01 00:00:00
abstract:IMPORTANCE:There is limited information about the durability of glycaemic control when different oral glucose-lowering therapies (GLTs) are used as add-on treatments to metformin (MET) in patients with type 2 diabetes mellitus (T2DM). OBJECTIVE:To compare time to treatment failure between different classes of oral GLT...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.3109/07853890.2016.1157263
更新日期:2016-01-01 00:00:00
abstract::It is established beyond doubt that free radicals in tissues and cells can damage DNA, proteins, carbohydrates and lipids. These potentially deleterious reactions are at least partly controlled by antioxidants capable of scavenging free radicals. It is widely believed that a proper balance between free radicals and an...
journal_title:Annals of medicine
pub_type: 杂志文章,评审
doi:10.3109/07853899409148366
更新日期:1994-12-01 00:00:00