Topical flurbiprofen in extracapsular cataract surgery: effect on pupillary diameter and iris fluorescein leakage.

Abstract:

:Recent clinical studies indicate that flurbiprofen, a cyclooxygenase inhibitor, prevents miosis and breakdown of the blood-aqueous barrier during cataract surgery. Yet based on clinical and experimental data, some researchers do not agree that flurbiprofen prevents miosis. We conducted a double-blind clinical study of the effects of topical 0.03% flurbiprofen sodium on intraoperative pupillary diameter and iris fluorescein leakage after extracapsular cataract surgery. In the first phase of the study, 120 patients who had extracapsular cataract extraction with posterior chamber intraocular lens implantation were randomly assigned to receive preoperative topical flurbiprofen or a placebo, with or without intraoperative epinephrine, in addition to the standard regimen. In the second phase, 60 of the 120 patients continued the topical flurbiprofen or placebo for one month postoperatively. Iris fluorescein angiography was performed at the end of the first and the fourth weeks. The results indicate that flurbiprofen was significantly more effective (P < .0001) in maintaining mydriasis during surgery than the placebo. This action was enhanced by intraoperative epinephrine. Flurbiprofen also significantly reduced (P < .001) postoperative iris fluorescein leakage.

authors

Cillino S,Casanova F,Cucco F,Ponte F

doi

10.1016/s0886-3350(13)80013-2

subject

Has Abstract

pub_date

1993-09-01 00:00:00

pages

622-5

issue

5

eissn

0886-3350

issn

1873-4502

pii

S0886-3350(13)80013-2

journal_volume

19

pub_type

临床试验,杂志文章,随机对照试验
  • Culture-negative ulcerative keratitis after laser in situ keratomileusis.

    abstract::A 40-year old man, highly myopic in both eyes, had laser in situ keratomileusis (LASIK) in the left eye in November 1996. Corneal melting and ulceration and fine striae-like interface infiltrates were noticed 1 day postoperatively. There was no response to intensive topical antibiotics in the form of hourly ofloxacin ...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/s0886-3350(99)00080-2

    authors: Lam DS,Leung AT,Wu JT,Fan DS,Cheng AC,Wang Z

    更新日期:1999-07-01 00:00:00

  • Change in the area of laser posterior capsulotomy: 3 month follow-up.

    abstract:PURPOSE:To monitor the change in the area of laser posterior capsulotomy over time to determine whether and when the area becomes stable. SETTING:Taipei Municipal Yang-Ming Hospital, Taipei, Taiwan, Republic of China. METHODS:This prospective study comprised 53 eyes (46 patients) with posterior capsule opacification ...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/s0886-3350(00)00645-3

    authors: Hu CY,Woung LC,Wang MC

    更新日期:2001-04-01 00:00:00

  • Unilateral corneal ectasia following small-incision lenticule extraction.

    abstract:UNLABELLED:We describe a case of unilateral corneal ectasia in a 26-year-old man following small-incision lenticule extraction. The preoperative corneal topography was normal, with a minimum corneal thickness of 511 μm and 513 μm in the right eye and left eye, respectively. Lenticules of 85 μm and 82 μm were fashioned ...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/j.jcrs.2015.08.006

    authors: Sachdev G,Sachdev MS,Sachdev R,Gupta H

    更新日期:2015-09-01 00:00:00

  • Measuring the power of an in situ intraocular lens with the keratometer.

    abstract::A method to measure the power of an intraocular lens (IOL) in situ using an extended range keratometer and a depth measuring apparatus is described. With this method, the IOL power was measured in ten patients with an anterior chamber IOL and in ten patients with a posterior chamber IOL and compared with the labeled p...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/s0886-3350(88)80066-x

    authors: Olsen T

    更新日期:1988-01-01 00:00:00

  • Influence of posterior corneal astigmatism on total corneal astigmatism in eyes with moderate to high astigmatism.

    abstract:PURPOSE:To evaluate the influence of posterior corneal astigmatism on total corneal astigmatism in patients with 1.00 diopter (D) or more of corneal astigmatism. SETTING:Private practice, Bologna, Italy. DESIGN:Prospective case series. METHODS:Corneal astigmatism was measured using a Scheimpflug camera combined with...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/j.jcrs.2014.01.046

    authors: Savini G,Versaci F,Vestri G,Ducoli P,Næser K

    更新日期:2014-10-01 00:00:00

  • Comparison of postoperative pain in patients following photorefractive keratectomy versus advanced surface ablation.

    abstract:PURPOSE:To compare postoperative pain associated with advanced surface ablation versus traditional photorefractive keratectomy (PRK). SETTING:Codet-Aris Vision Institute, Tijuana, Mexico. METHODS:This prospective double-masked randomized study included 56 eyes of 28 myopic patients who received traditional PRK in 1 e...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/j.jcrs.2004.11.046

    authors: Blake CR,Cervantes-Castañeda RA,Macias-Rodríguez Y,Anzoulatous G,Anderson R,Chayet AS

    更新日期:2005-07-01 00:00:00

  • Functional vision with cataracts of different morphologies: comparative study.

    abstract:PURPOSE:To evaluate the influence of cataract morphology on the functional vision of patients with age-related cataract and normal macular function and compare subjectively perceived functional impairments to distance visual acuity, reading acuity, and maximum reading speed between cataract types. SETTING:Department o...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/j.jcrs.2004.01.038

    authors: Stifter E,Sacu S,Weghaupt H

    更新日期:2004-09-01 00:00:00

  • Epidemiology of retinal detachment following extracapsular cataract extraction: a follow-up study with an analysis of risk factors.

    abstract::We reviewed the medical records of 1,726 eyes consecutively operated on with extracapsular cataract extraction to examine the incidence of and the risk factors for retinal detachment (RD). In Denmark, both diagnoses and deaths are registered centrally; therefore, a complete follow-up was achieved in each case and actu...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/s0886-3350(13)80333-1

    authors: Nielsen NE,Naeser K

    更新日期:1993-11-01 00:00:00

  • Near-point string: Simple method to demonstrate anticipated near point for multifocal and accommodating intraocular lenses.

    abstract:UNLABELLED:We present a technique that uses a near-point string to demonstrate the anticipated near point of multifocal and accommodating intraocular lenses (IOLs). Beads are placed on the string at distances corresponding to the near points for diffractive and accommodating IOLs. The string is held up to the patient's...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/j.jcrs.2016.04.003

    authors: George MC,Lazer ZP,George DS

    更新日期:2016-05-01 00:00:00

  • Biomechanical characteristics of the ectatic cornea.

    abstract::The ocular response analyzer (ORA) (Reichert, Inc.) was used in the case of a middle-aged man who developed unilateral corneal ectasia after bilateral laser in situ keratomileusis (LASIK). The preoperative refraction was similar in the 2 eyes. Post-LASIK ectasia was central in the left eye; topography was oblate in th...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/j.jcrs.2007.11.018

    authors: Kerautret J,Colin J,Touboul D,Roberts C

    更新日期:2008-03-01 00:00:00

  • Astigmatically neutral sutured small incision.

    abstract::The desire for rapid visual rehabilitation following phacoemulsification for cataract and intraocular lens implantation has stimulated a quest for an "astigmatically neutral" incision. We have evaluated an underemphasized aspect of wound closure technique for a small incision wound (5.1 mm). The essential element of t...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/s0886-3350(13)80688-8

    authors: Pacifico RL,Morrison C

    更新日期:1991-01-01 00:00:00

  • Effect of mitomycin-C on the variance in refractive outcomes after photorefractive keratectomy.

    abstract:PURPOSE:To compare the variance in manifest refraction spherical equivalent (MRSE) after photorefractive keratectomy (PRK) with mitomycin-C (MMC), PRK without MMC, and laser in situ keratomileusis (LASIK) for the treatment of myopic astigmatism. SETTING:Jules Stein Eye Institute, University of California, Los Angeles,...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/j.jcrs.2014.02.048

    authors: Sy ME,Zhang L,Yeroushalmi A,Huang D,Hamilton DR

    更新日期:2014-12-01 00:00:00

  • Safety and efficacy of incisional goniotomy as an adjunct with phacoemulsification in primary angle-closure glaucoma.

    abstract:PURPOSE:To evaluate the intraocular pressure (IOP)-lowering efficacy and safety of incisional goniotomy as an adjunct to phacoemulsification in primary angle-closure glaucoma (PACG) patients. METHODS:In this prospective interventional case series, consecutive patients with PACG (high or borderline IOP) deemed fit for ...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1097/j.jcrs.0000000000000481

    authors: Gupta S,Sethi A,Yadav S,Optom M,Azmira K,Singh A,Gupta V

    更新日期:2020-11-19 00:00:00

  • Contrast sensitivity measured by 2 methods after photorefractive keratectomy.

    abstract:PURPOSE:To study contrast sensitivity in eyes that had flying-spot excimer laser photorefractive keratectomy (PRK) and to compare a subjective method (Vision Contrast Test System [VCTS] 6500) and an objective method (visual evoked potential [VEP]) of measuring contrast sensitivity. SETTING:Istituto Clinica Oculistica,...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/s0886-3350(00)00405-3

    authors: Vetrugno M,Quaranta GM,Maino A,Mossa F,Cardia L

    更新日期:2000-06-01 00:00:00

  • Pigmentary dispersion syndrome with a secondary piggyback 3-piece hydrophobic acrylic lens. Case report with clinicopathological correlation.

    abstract::We describe a case of pigmentary dispersion syndrome resulting from secondary piggyback implantation of a 3-piece hydrophobic acrylic squared-edged intraocular lens (IOL) in the ciliary sulcus. The intraocular pressure remained elevated despite pharmacological treatment, with a heavily pigmented trabecular meshwork. T...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/j.jcrs.2007.01.044

    authors: Chang WH,Werner L,Fry LL,Johnson JT,Kamae K,Mamalis N

    更新日期:2007-06-01 00:00:00

  • Prospective study of posterior capsule-zonular disruption during extracapsular cataract extraction: eliminating iatrogenic disruption.

    abstract::We modified our surgical techniques after analyzing the mechanisms responsible for posterior capsule-zonular disruption with or without vitreous loss in 250 consecutive extracapsular cataract extraction cases. We applied the derived principles and prospectively studied the subsequent 1,500 cases. Modifications in our ...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/s0886-3350(13)80704-3

    authors: O'Donnell FE Jr,Santos BA

    更新日期:1990-05-01 00:00:00

  • Safety and predictability of laser in situ keratomileusis enhancement by flap reelevation in high myopia.

    abstract:PURPOSE:To evaluate the safety and predictability of laser in situ keratomileusis (LASIK) retreatment following primary procedures for high myopia and astigmatism. SETTING:Corneal Diseases and Excimer Laser Research Unit, Department of Ophthalmology, University of Dundee, Dundee, United Kingdom. METHODS:This prospect...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/s0886-3350(01)00765-9

    authors: Brahma A,McGhee CN,Craig JP,Brown AD,Weed KH,McGhee J,Brown R

    更新日期:2001-04-01 00:00:00

  • Trocar anterior chamber maintainer: Improvised infusion technique.

    abstract:UNLABELLED:We present an improvised technique of infusion that uses a trocar cannula as an anterior chamber maintainer (ACM). Although routinely used in posterior segment surgery, the trocar cannula has been infrequently used in complex anterior segment procedures. The trocar ACM creates a transconjunctival biplanar wo...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/j.jcrs.2016.01.015

    authors: Agarwal A,Narang P,Kumar DA,Agarwal A

    更新日期:2016-02-01 00:00:00

  • Elevated intraocular pressure in secondary piggyback intraocular lens implantation.

    abstract::We report 2 cases of postoperative intraocular pressure (IOP) elevation in secondary piggyback intraocular lens (IOL) implantation without history of glaucoma or ocular hypertension. A 74-year-old woman with myopic pseudophakia and a 68-year-old man with hyperopic pseudophakia received secondary piggyback AcrySof IOL ...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/j.jcrs.2005.06.034

    authors: Iwase T,Tanaka N

    更新日期:2005-09-01 00:00:00

  • Posterior chamber intraocular lens implantation in ethnic minorities by resident housestaff.

    abstract::The first 45 cases of extracapsular cataract extraction, with posterior chamber intraocular lens implantation performed by ophthalmology residents at an urban county hospital were evaluated. These cases, which were performed from March 1983 to June 1984, involved a patient population that was primarily black and Hispa...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/s0886-3350(86)80054-2

    authors: Ullman HE,Gonzalez AA,Bath PE,Prendiville K,Cox KC,Alston A

    更新日期:1986-01-01 00:00:00

  • Comparison of corneal power, corneal astigmatism, and axis location in normal eyes obtained from an autokeratometer and a corneal topographer.

    abstract:PURPOSE:To assess the repeatability and agreement of corneal power, corneal astigmatism, axis location, and astigmatic vector component measurements using an autokeratometer and a corneal topographer in healthy subjects. SETTING:Department of Ophthalmology, Kitasato University, Kanagawa, Japan. DESIGN:Evaluation of d...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/j.jcrs.2011.11.026

    authors: Kobashi H,Kamiya K,Igarashi A,Ishii R,Sato N,Wang G,Shimizu K

    更新日期:2012-04-01 00:00:00

  • Sex hormones and their receptors in patients with age-related cataract.

    abstract:PURPOSE:To determine the sex hormone levels in the serum and aqueous humor in patients with age-related cataract and the corresponding hormone receptors in cataract lens epithelial cells (LECs). SETTING:Research Laboratory, International Intraocular Implant Training Center, Tianjin Medical University, Tianjin, China. ...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/s0886-3350(02)01436-0

    authors: Zhang XH,Sun HM,Ji J,Zhang H,Ma WJ,Jin Z,Yuan JQ

    更新日期:2003-01-01 00:00:00

  • Intraocular pressure variation during femtosecond laser-assisted cataract surgery using a fluid-filled interface.

    abstract:PURPOSE:To evaluate intraocular pressure (IOP) during femtosecond laser-assisted cataract surgery using a fluid-filled interface. SETTING:Ruhr University Eye Clinic, Bochum, Germany. DESIGN:Prospective clinical trial. METHODS:The absolute IOP was measured with a modified Schiotz tonometer before and after laser-assi...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.jcrs.2012.10.038

    authors: Schultz T,Conrad-Hengerer I,Hengerer FH,Dick HB

    更新日期:2013-01-01 00:00:00

  • Biometry of cataractous eyes using partial coherence interferometry: clinical feasibility study of a commercial prototype I.

    abstract:PURPOSE:To evaluate the clinical feasibility of the prototype version of a commercial partial coherence interferometry instrument (axial length measurement, ALM, Carl Zeiss Jena) for noninvasive, high-precision biometry in cataractous eyes. SETTING:Department of Ophthalmology, Vienna General Hospital, and Institute of...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0886-3350(01)01272-x

    authors: Kiss B,Findl O,Menapace R,Wirtitsch M,Drexler W,Hitzenberger CK,Fercher AF

    更新日期:2002-02-01 00:00:00

  • Histology of anterior capsule opacification with a polyHEMA/HOHEXMA hydrophilic hydrogel intraocular lens compared to poly(methyl methacrylate), silicone, and acrylic lenses.

    abstract::To evaluate the biocompatibility of various materials including a poly(2-hydroxyethyl methacrylate [HEMA])/(6-hydroxyhexyl methacrylate [HOHEXMA]) hydrophilic hydrogel intraocular lens (IOL) (Hydroview, Bausch & Lomb). Department of Ophthalmology, Wakayama Medical University, Wakayama, Japan. Ten opacified anterior ca...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/s0886-3350(02)01988-0

    authors: Saika S,Miyamoto T,Ohnishi Y

    更新日期:2003-06-01 00:00:00

  • Collagen copolymer toric posterior chamber phakic intraocular lens in eyes with keratoconus.

    abstract:PURPOSE:To assess the safety, efficacy, stability, and predictability of collagen copolymer toric phakic intraocular lens (pIOL) implantation to correct myopia and astigmatism in eyes with keratoconus. SETTING:Fernández-Vega Ophthalmological Institute, Oviedo, Spain. METHODS:This prospective study comprised keratocon...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/j.jcrs.2009.11.032

    authors: Alfonso JF,Fernández-Vega L,Lisa C,Fernandes P,González-Méijome JM,Montés-Micó R

    更新日期:2010-06-01 00:00:00

  • Risk factors for endophthalmitis after cataract surgery: Predictors for causative organisms and visual outcomes.

    abstract:PURPOSE:To investigate visual outcome, bacteriology, and time to diagnosis in groups identified as being at risk for endophthalmitis following cataract surgery. SETTING:Swedish National Cataract Register. DESIGN:A retrospective review of postoperative endophthalmitis and control cases reported from 2002 to 2010. MET...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/j.jcrs.2015.05.027

    authors: Lundström M,Friling E,Montan P

    更新日期:2015-11-01 00:00:00

  • Excimer laser intrastromal keratomileusis: case reports.

    abstract::We report the results in six eyes on which we performed a new surgical method: intrastromal corneal excimer laser photoablation following lamellar corneal keratectomy with a microkeratome. The study was designed to evaluate the clinical and refractive efficacy of the procedure, to assess the behavior of the cornea fol...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/s0886-3350(13)80381-1

    authors: Buratto L,Ferrari M

    更新日期:1992-01-01 00:00:00

  • Visual acuity after penetrating keratoplasty for pseudophakic and aphakic bullous keratopathy.

    abstract:PURPOSE:To identify prognostic factors that determine the visual acuity after penetrating keratoplasty (PKP) for bullous keratopathy secondary to cataract surgery. SETTING:Department of Ophthalmology, University Hospital Antwerp, Antwerp, Belgium. METHODS:Twenty-six patients who had PKP for bullous keratopathy were e...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/s0886-3350(02)01742-x

    authors: Schraepen P,Koppen C,Tassignon MJ

    更新日期:2003-03-01 00:00:00

  • Efficacy and safety of a new selective laser device to create anterior capsulotomies in cataract patients.

    abstract:PURPOSE:To compare the efficacy and safety of anterior capsulotomy creation with a new selective laser device (CAPSULaser) with those of manual capsulotomies. SETTING:GEMINI Eye Clinic, Zlin, Czech Republic. DESIGN:Prospective case series. METHODS:Patients were placed in cohorts based on age and cataract grade and r...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/j.jcrs.2018.12.012

    authors: Stodulka P,Packard R,Mordaunt D

    更新日期:2019-05-01 00:00:00