MRI of the brain with ultra-short echo-time pulse sequences.

Abstract:

:As well as the long-T2 relaxation components normally detected with conventional imaging techniques, the brain has short-T2 components. We wished to use ultra-short (0.08 ms) echo time (UTE) pulse sequences to assess the feasibility of imaging these in normal subjects and patients. UTE sequences were employed, with or without fat suppression, 90 degree long-T2 suppression pulses, and selective nulling of long-T2 components using an inversion pulse. Subtraction of later echoes from the first was also used to reduce the signal from long-T2 components. We studied dive normal subjects and 15 patients with various diseases. Short-T2 components were demonstrated in grey and white matter. Increased signal from these components was seen in meningeal disease, probable calcification, presumed cavernomas, melanoma metastases and probable gliosis. Reduced signal was seen in some tumours, infarcts, mild multifocal vascular disease and vasogenic oedema. Further development and evaluation of these pulse sequences is warranted.

journal_name

Neuroradiology

journal_title

Neuroradiology

authors

Waldman A,Rees JH,Brock CS,Robson MD,Gatehouse PD,Bydder GM

doi

10.1007/s00234-003-1076-z

subject

Has Abstract

pub_date

2003-12-01 00:00:00

pages

887-92

issue

12

eissn

0028-3940

issn

1432-1920

journal_volume

45

pub_type

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