A surface antigen delineating a subset of neurons in the primary somatosensory cortex of the mouse.

Abstract:

:Synapsins are a family of proteins associated with synaptic vesicles that are widely used as markers of synaptic terminals. We decided to investigate synapsin I expression in the mouse primary somatosensory cortex (SI). Immunostaining experiments using a polyclonal antibody against C-terminal domain of synapsin Ia/b (anti-SynI-C) showed an unusual pattern in the SI cortex compared to other regions of the neocortex. The staining delineated the cells located in barrel hollows. The immunoreactive product was located on the perikarya and proximal dendrites of gabaergic neurons found in layer IV and VI of the SI cortex. Other anti-synapsin antibodies did not reveal this pattern within the SI cortex, although in the hippocampus all antibodies examined produced a similar pattern of immunostaining. Deglycosylation of sections resulted in complete loss of immunodecoration on the cell perikarya. We suggest that the anti-SynI-C recognizes a saccharide surface epitope, possibly an element of perineuronal nets that is specific for the primary somatosensory cortex.

authors

Nowicka D,Liguz-Lecznar M,Skangiel-Kramska J

subject

Has Abstract

pub_date

2003-01-01 00:00:00

pages

185-95

issue

3

eissn

0065-1400

issn

1689-0035

journal_volume

63

pub_type

杂志文章
  • The contralateral impairment of the orienting ocular-following reflex after lesions of the lateral suprasylvian cortex in cats.

    abstract::The cortex of the middle suprasylvian sulcus was removed unilaterally in cats with brain stem transected at the pretrigeminal level. The vertical following reflex was evoked by a slit of light (1 degree x 4 degrees) moving along the vertical meridian or parallel to it up to 40 degrees in the left or right hemifield. T...

    journal_title:Acta neurobiologiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Zernicki B,Stasiak M

    更新日期:1994-01-01 00:00:00

  • Neural commitment of cord blood stem cells (HUCB-NSC/NP): therapeutic perspectives.

    abstract::Human umbilical cord blood (HUCB) is considered a promising source of neural progenitors capable of being used for cellular therapies in neurological disorders. Here we review briefly our work on the elucidation of mechanisms and development of practical standards as regards the selection, maintenance and use of cord ...

    journal_title:Acta neurobiologiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Domanska-Janik K,Habich A,Sarnowska A,Janowski M

    更新日期:2006-01-01 00:00:00

  • Genetic engineering of stem cells for enhanced therapy.

    abstract::Stem cell therapy is a promising strategy for overcoming the limitations of current treatment methods. The modification of stem cell properties may be necessary to fully exploit their potential. Genetic engineering, with an abundance of methodology to induce gene expression in a precise and well-controllable manner, i...

    journal_title:Acta neurobiologiae experimentalis

    pub_type: 杂志文章,评审

    doi:

    authors: Nowakowski A,Andrzejewska A,Janowski M,Walczak P,Lukomska B

    更新日期:2013-01-01 00:00:00

  • Alimentary vs. nonalimentary behavior in rats with medial amygdala lesions.

    abstract::Three types of behavior in three different groups of animals were studied: (i) water and food intake, (ii) instrumental performance reinforced by water or food, and (iii) spontaneous locomotor activity. Amygdalar rats, in comparison with control ones, revealed a transient decrease in the total amount of the unconditio...

    journal_title:Acta neurobiologiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Korczyński R

    更新日期:1980-01-01 00:00:00

  • The presylvian cortex as a transitional prefronto-motor zone in dog.

    abstract::Connnections of the cortical region situated in the medial and lateral walls of the presylvian fissure in the dog were investigated using the method of retrograde HRP transport. The patterns of subcortico-cortical and cortico-cortical projections sho,w that the cortical field of the medial presylvian wall (paraorbital...

    journal_title:Acta neurobiologiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Kosmal A,Markow G,Stepniewska I

    更新日期:1984-01-01 00:00:00

  • Tight junctions in neurological diseases.

    abstract::Tight junction, one of the type of cell-cell junctions, controls the paracellular permeability across the lateral intercellular space and maintains the cell polarity. Tight junctions consist of transmembrane proteins: members of tight junction-associated MARVEL protein (TAMP) family, claudins and junctional adhesion m...

    journal_title:Acta neurobiologiae experimentalis

    pub_type: 杂志文章,评审

    doi:

    authors: Bednarczyk J,Lukasiuk K

    更新日期:2011-01-01 00:00:00

  • Structure of cytomatrix and nuclear matrix revealed by embedment-free electron microscopy.

    abstract::Embedment-free electron microscopy (EFEM) is a new method which allows the visualisation of cytoskeleton in whole-mounted cells. In this study we employed EFEM to investigate the structure of cellular scaffolds in glioma C6 cell line. The cells were extracted with Triton X-100 that dissolves phospholipids in the membr...

    journal_title:Acta neurobiologiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Gajkowska B,Cholewiński M,Gniadecki R

    更新日期:2000-01-01 00:00:00

  • Some questions related to mechanisms of slave-raids in Amazon-ant Polyergus rufescens Latr.

    abstract::A new hypothesis concerning the mechanism of the P. rufescens' slave-raids, is proposed. (i) The so-called pseudo-scouting does not contribute to the slave-raids. (ii) The direction of the raid is determined by the random movement of the most easily aroused individuals - the so-called activists. (iii) Once the directi...

    journal_title:Acta neurobiologiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Dobrzański J,Dobrzańska J

    更新日期:1978-01-01 00:00:00

  • Supraspinal influences on spinal mechanisms activated prior to learned movement.

    abstract::Dogs were trained to perform an instrumental avoidance reflex of lifting and holding a limb above a pre-determined level to prevent or to interrupt painful stimulation of the same limb. A tone preceding the stimulation by 0.5 s served as the CS. During the CS the excitability of the motoneuronal pools involved in the ...

    journal_title:Acta neurobiologiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Ioffe ME

    更新日期:1973-01-01 00:00:00

  • The effect of bovine fibrinopeptides on the central action of chlorpromazine and amphetamine in rats.

    abstract::A mixture of fibrinopeptides A and B did not evoke any significant central effects when given by intraperitoneal injection, whereas it increased psychomotor activity when injected into a cerebral ventricle. The fibrinopeptides when given by intraperitoneal injection interacted with amphetamine to increase locomotor ac...

    journal_title:Acta neurobiologiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Buczko W

    更新日期:1976-01-01 00:00:00

  • Modulation of anxiety behavior in gonadectomized animals.

    abstract::Anxiety is a complex psychological state which happens after stressful life experiences. Many factors such as daily life events, neurotransmitter systems, and different brain areas could influence anxiety behavior in humans and animals. For example, opioids and androgens decrease anxiety behavior both in humans and an...

    journal_title:Acta neurobiologiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Khakpay R,Khakpai F

    更新日期:2020-01-01 00:00:00

  • Searching for oligodendrocyte precursors for cell replacement therapies.

    abstract::Inherited or acquired oligodendrocyte deficiency or abnormalities usually lead to severe neurological disorders, common in humans and animals. The wide spectrum of diseases to be treated, their frequency and lack of effective treatments result in an urgent need to elaborate alternative options such as cell replacement...

    journal_title:Acta neurobiologiae experimentalis

    pub_type: 杂志文章,评审

    doi:

    authors: Sypecka J

    更新日期:2011-01-01 00:00:00

  • Changes of some postural reflexes during the first postnatal weeks in the dog.

    abstract::During the first two postnatal weeks postural reflexes were either absent or abortive. First adult-like patterns of reactions were seen at the end of the 3rd week but they could be regularly elicited only by the 6th-9th week. ...

    journal_title:Acta neurobiologiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Czarkowska J

    更新日期:1983-01-01 00:00:00

  • Developmental expression of major myelin proteins in hypomyelinated pt mutant rabbit.

    abstract::A term "paralytic tremor" (pt) is attributed to a neurological mutation of Chinchilla rabbits, affecting the development of the central nervous system (CNS). A quantification of myelin protein content indicates the strong CNS hypomyelination during the development (1-120 postnatal days). SDS-PAGE electrophoresis of to...

    journal_title:Acta neurobiologiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Sypecka J,Tosic M,Dolivo M,Domańska-Janik K,Matthieu JM

    更新日期:1993-01-01 00:00:00

  • The interplay between parkin and alpha-synuclein; possible implications for the pathogenesis of Parkinson's disease.

    abstract::Parkin and alpha-synuclein (α-syn) are two key proteins involved in the pathophysiology of Parkinson's disease (PD). Oligomerization/aggregation and excessive secretion of α-syn contributes to PD through free radical stress, mitochondrial impairment, and synaptic dysfunction. Parkin, an E3 ubiquitin ligase, is conside...

    journal_title:Acta neurobiologiae experimentalis

    pub_type: 杂志文章,评审

    doi:

    authors: Jęśko H,Lenkiewicz AM,Wilkaniec A,Adamczyk A

    更新日期:2019-01-01 00:00:00

  • A visual deficit after superior colliculus lesions in monkeys.

    abstract::The superior colliculus has been implicated in visual orientation and localization in several mammalian species. To examine this possibility in rhesus monkeys, we trained monkeys to respond to one of six locations signaled by a small light of 5 s duration that was turned off immediately before they were allowed to res...

    journal_title:Acta neurobiologiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: MacKinnon DA,Gross CG,Bender DB

    更新日期:1976-01-01 00:00:00

  • Auto-shaping or orienting?

    abstract::Four experiments were carried out to study the development of the orienting response (OR) under different experimental conditions in the cat and rat. In Experiment I and II (cat) and Experiment IV (rat) classical CS-US pairing was used (with food, shock and water reinforcers, respectively). In Experiment III (cat) an ...

    journal_title:Acta neurobiologiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Buzsáki G,Grastyán E,Molnár P,Tveritskaya IN,Haubenreiser J

    更新日期:1979-01-01 00:00:00

  • Responses of red nucleus neurons to peripheral stimulation in chloralose anesthetized cats.

    abstract::Spontaneous and evoked activity of red nucleus neurons is described in chloralose anesthetized cats. It is suggested that some effects, e.g. burst discharges and prolonged inhibitory-excitatory responses, were induced by the use of chloralose. ...

    journal_title:Acta neurobiologiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Rajkowski J

    更新日期:1982-01-01 00:00:00

  • Effects of prefrontal lesions on left leg-right leg differentiation in dogs.

    abstract::Twenty five animals trained in the left leg-right leg differentiation were given orbital, proreal or medial precruciate lesions. Pure cortical ablations did not affect the task whereas these deep lesions involving the bundle of fibers inside the prefrontal region caused severe deficit. The medial lesions (superficial ...

    journal_title:Acta neurobiologiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Stepień I,Stepień L

    更新日期:1972-01-01 00:00:00

  • ERPs and the evoked cardiac response to auditory stimuli: Intensity and cognitive load effects.

    abstract::The evoked cardiac response (ECR) may be described as the sum of two independent response components: an initial HR deceleration (ECR1) and a slightly later acceleration (ECR2) hypothesized to reflect stimulus registration and cognitive processing load, respectively. This study investigated processing load effects in ...

    journal_title:Acta neurobiologiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Lawrence CA,Barry RJ

    更新日期:2009-01-01 00:00:00

  • Higher reflexes: an attempt at comprehensive classification of neuro-behavioral activity.

    abstract::The term reflex is used in its widest sense and denotes the neural processes and effector responses controlled by the evoking stimulus and the feedback stimuli. The reflexes having their specific component facilitated by drive central processes are denoted as higher. Escape, avoidance and approach higher reflexes are ...

    journal_title:Acta neurobiologiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Zernicki B

    更新日期:1972-01-01 00:00:00

  • Memory for object and object-location after lesions to the ventromedial prefrontal cortex in humans.

    abstract::The aim of the present study was to investigate the effect of small unilateral lesions to the ventromedial portion of the prefrontal cortex on two memory functions: memory for objects and memory for object locations. Patients, who had undergone surgery of the anterior communicating artery aneurysm, and normal control ...

    journal_title:Acta neurobiologiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Szatkowska I,Grabowska A,Szymańska O

    更新日期:2003-01-01 00:00:00

  • Konorski and conditional reflexes: a historical summary and an addendum.

    abstract::There have been four major pioneers from Eastern Europe in the neuroscientific study of memory and learning: Pavlov, Bekhterev, Beritashvili and Konorski. The thinking of each evolved with the progress of neuroscientific knowledge throughout the world, and save for Pavlov, each encountered governmental opposition to t...

    journal_title:Acta neurobiologiae experimentalis

    pub_type: 传,历史文章,杂志文章

    doi:

    authors: Doty RW

    更新日期:2006-01-01 00:00:00

  • Effect of posterior hypothalamic injection of procaine on the hippocampal theta rhythm in freely moving cats.

    abstract::Earlier in vivo studies conducted on freely moving and anesthetized rats demonstrated that the posterior hypothalamus (PH) comprises pathways critical for producing the synchronous hippocampal formation (HPC) theta rhythm. In addition, these findings suggested that the frequency of the HPC theta was encoded in the PH ...

    journal_title:Acta neurobiologiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Bocian R,Konopacki J

    更新日期:2001-01-01 00:00:00

  • Experimental modeling of anxiety and depression.

    abstract::Anxiety and depression have dramatic impact on human and animal behaviors. We take an interdisciplinary approach and review the existing experimental models of anxiety and depression in order to promote further understanding of neurobiological aspects of anxiety and depression. ...

    journal_title:Acta neurobiologiae experimentalis

    pub_type: 杂志文章,评审

    doi:

    authors: Kalueff AV,Tuohimaa P

    更新日期:2004-01-01 00:00:00

  • The participation of serotoninergic system in the regulation of emotional-defensive behavior evoked by intrahypothalamic carbachol injections in the cat.

    abstract::The influence of bilateral injections of serotonin (5-HT) and methysergide (MET) to antero-medial hypothalamus (HA) on carbachol-induced emotional-defensive behavior was investigated. Earlier (15 min) stimulation of 5-HT receptors in HA region by 5-HT injections evoked a decrease in the level of vocal response (number...

    journal_title:Acta neurobiologiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Gołebiewski H,Romaniuk A

    更新日期:1985-01-01 00:00:00

  • The effect of dissection of corpus callosum on differentiation of instrumental reflexes to symmetrical tactile stimuli in dogs.

    abstract::In normal dogs a differentiation task consisting of lifting the left or right foreleg in response to the tactile stimuli administered to the left or right side of the body respectively is very difficult, requiring from 500 to 1,000 trials. On the contrary the same task presented to other dogs after transection of the ...

    journal_title:Acta neurobiologiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Dobrzecka C,Konorski J

    更新日期:1973-01-01 00:00:00

  • Prostacyclin reduces early ischemic changes in central nervous system.

    abstract::The authors made a study of the effect of prostacyclin (PGI2) on ischemic morphological changes in the brain, extracellular calcium concentration (Ca2+e) and the blood-brain barrier (BBB) permeability. This was combined with physiological and neurophysiological measurements. Complete cerebral ischemia (CCI) lasting 15...

    journal_title:Acta neurobiologiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Pluta R,Salińska E,Lazarewicz JW

    更新日期:1990-01-01 00:00:00

  • Effects of cardiac vagotomy on heart rate conditioned responses in cats.

    abstract::Normal cats were bilaterally vagotomized at cardiac level and submitted to a classical defensive conditioning using excitatory, inhibitory and differential stimuli. That group was compared with a normal one. Both groups showed an anticipatory bradycardia to the noxious excitatory stimulus and a late deceleration to th...

    journal_title:Acta neurobiologiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Giavelli A,Astorga L,Santibáñez-H G

    更新日期:1977-01-01 00:00:00

  • Changes in cortical and hippocampal EEG activity accompanying spontaneous electrocortical seizures in rats.

    abstract::The purpose of the present study was to find out whether the occurrence of bursts of spontaneous spike-wave discharges (SWD) in rat neocortex is related to a particular state of vigilance (level of arousal), as some authors suggested, or rather to transitions from one state to another as postulated by others. Patterns...

    journal_title:Acta neurobiologiae experimentalis

    pub_type: 杂志文章

    doi:

    authors: Gralewicz S,Luczak C

    更新日期:1994-01-01 00:00:00