Repeat participation among normal healthy research volunteers: professional guinea pigs in clinical trials?

Abstract:

:The recent death of a normal healthy volunteer, as well as the increased use of normal volunteers as research subjects, has heightened the attention given to the participation of normal volunteers in clinical research. An overlooked sub-population of normal healthy volunteers are repeat, veteran volunteers. This essay discusses ethical and methodological issues associated with the use of repeat volunteers in research, along with existing guidelines regarding the use of repeat healthy volunteers, and concludes with recommendations for safeguarding repeat volunteers and ideas supporting centralized recruiting.

journal_name

Perspect Biol Med

authors

Tishler CL,Bartholomae S

doi

10.1353/pbm.2003.0094

subject

Has Abstract

pub_date

2003-10-01 00:00:00

pages

508-20

issue

4

eissn

0031-5982

issn

1529-8795

pii

S1529879503405085

journal_volume

46

pub_type

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