Abstract:
:Traumatic brain injury (TBI) is one of the commonest causes of morbidity and mortality in the developed countries with posttraumatic epilepsy and functional disability being its major sequelae. The purpose of this study was to test the hypothesis whether the normal appearing adjacent gray and white matter regions on T2 and T1 weighted magnetization transfer (MT) weighted images show any abnormality on quantitative imaging in patients with TBI. A total of 51 patients with TBI and 10 normal subjects were included in this study. There were significant differences in T2 and MT ratio values of T2 weighted and T1 weighted MT normal appearing gray matter regions adjacent to focal image abnormality compared to normal gray matter regions in the normal individuals as corresponding contralateral regions of the TBI patient's group (p < 0.05). However the adjoining normal appearing white matter quantitative values did not show any significant change compared to the corresponding contralateral normal white matter values. We conclude that quantitative T2 and MT ratio values provide additional abnormality in patients with TBI that is not discernable on conventional T2 weighted and T1 weighted MT imaging especially in gray matter. This additional information may be of value in overall management of these patients with TBI.
journal_name
Magn Reson Imagingjournal_title
Magnetic resonance imagingauthors
Kumar R,Gupta RK,Rao SB,Chawla S,Husain M,Rathore RKdoi
10.1016/s0730-725x(03)00189-9subject
Has Abstractpub_date
2003-10-01 00:00:00pages
893-9issue
8eissn
0730-725Xissn
1873-5894pii
S0730725X03001899journal_volume
21pub_type
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