Urticarial lesions in a child with acute lymphoblastic leukemia and eosinophilia.

abstract：BACKGROUND:Phosphodiesterase-4 (PDE4) is a promising target in atopic dermatitis (AD) treatment. The pharmacokinetics (PK), safety, and efficacy of crisaborole topical ointment, 2% (formerly AN2728) (Anacor Pharmaceuticals, Palo Alto, CA), a boron-based benzoxaborole PDE4 inhibitor, were evaluated in children with mild...

journal_title：Pediatric dermatology

authors： Zane LT,Kircik L,Call R,Tschen E,Draelos ZD,Chanda S,Van Syoc M,Hebert AA

更新日期：2016-07-01 00:00:00

abstract：:Chilblains, or pernio, are cutaneous lesions that may accompany systemic illnesses including states of malnutrition and autoimmune diseases. We report an adolescent girl in whom chilblains were the chief presenting sign of celiac disease. A gluten-free diet led to weight gain and resolution of the chilblains. We specu...

journal_title：Pediatric dermatology

authors： St Clair NE,Kim CC,Semrin G,Woodward AL,Liang MG,Glickman JN,Leichtner AM,Binstadt BA

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Treatment of palmar and axillary primary focal hyperhidrosis (PFH) in children up to 16 years using thoracoscopic sympathicotomy is supported by scarce evidence. Therefore, this study aimed to summarize the results of our standardized bilateral, one-stage, single-port sympathicotomy (BOSS) in children up to ...

journal_title：Pediatric dermatology

authors： Verhaegh AJFP,Kuijpers M,Boon M,DeJongste MJL,Bouma W,Mariani MA,Klinkenberg TJ

更新日期：2020-09-01 00:00:00

abstract：:Microvenular hemangioma (MVH) is a rare, benign, acquired vascular tumor. We report a case that shows the characteristic histopathologic features of this disorder in a boy with acute myelogenous leukemia (AML), suggesting an association with systemic immunosuppression. ...

journal_title：Pediatric dermatology

authors： Chang SE,Roh KH,Lee MW,Choi JH,Sung KJ,Moon KC,Koh JK,Yoon GS

更新日期：2003-05-01 00:00:00

abstract：:One morphologic feature of Turner syndrome is increased numbers of melanocytic nevi; however, little attention has been given to their characterization. The development of a melanoma in one of our patients with Turner syndrome prompted this study. We prospectively examined 10 patients with the disease, confirmed by ka...

journal_title：Pediatric dermatology

authors： Becker B,Jospe N,Goldsmith LA

更新日期：1994-06-01 00:00:00

abstract：INTRODUCTION:Extravasation injuries are a common and challenging problem in hospitalized newborns. Accidental infusion leakage into the surrounding tissues in immature infants may frequently result in skin necrosis, with significant risk of functional and cosmetic impairment. MATERIAL AND METHODS:In the present study ...

journal_title：Pediatric dermatology

authors： Kostogloudis N,Demiri E,Tsimponis A,Dionyssiou D,Ioannidis S,Chatziioannidis I,Nikolaidis N

更新日期：2015-11-01 00:00:00

abstract：:Lichen striatus is a common childhood eruption, but only rare reports link cutaneous manifestations and onychodystrophy. We report a case of lichen striatus and onychodystrophy in a 12-year-old girl, only the eighth such patient in the dermatologic literature. Nail changes may precede the rash of lichen striatus and s...

journal_title：Pediatric dermatology

authors： Karp DL,Cohen BA

更新日期：1993-12-01 00:00:00

abstract：:A 6-month-old baby had erythema, fissuring of the skin, and craquelé due to prolonged use of a liquid soap mistakenly believed to be a moisturizer. We think these kinds of skin disorders will become increasingly common due to such misunderstandings. The proliferation of cosmetic products for baby skin care, the increa...

journal_title：Pediatric dermatology

authors： Menni S,Brauner I,Tsavdari T

更新日期：1993-09-01 00:00:00

abstract：:Rothmund-Thomson syndrome, a rare autosomal recessive disorder, is characterized by photosensitivity; specific skin changes including poikiloderma, atrophy, and telangiectases; juvenile cataracts; short stature; and bone defects. We describe two siblings with this syndrome. ...

journal_title：Pediatric dermatology

authors： Nanda A,Kanwar AJ,Kapoor MM,Thappa DM,Radotra BD,Vaishnavi C,Kaur S

更新日期：1989-12-01 00:00:00

abstract：:X-linked chronic granulomatous disease (CGD), a defect of leukocyte bactericidal capacity, was seen in three generations of a large kindred. The association of discoid lupus erythematosus (DLE) with CGD was noted. Recurrent antigenic stimulation leading to autoantibody formation may explain the apparently increased fr...

journal_title：Pediatric dermatology

authors： Barton LL,Johnson CR

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND/OBJECTIVES:Palmar hyperlinearity is a typical clinical feature of Filaggrin gene (FLG) null mutations. There are reports of FLG mutations and allergic sensitization; however, reports on the relationship between palmar hyperlinearity to sensitization are limited. This study aimed to examine the association be...

journal_title：Pediatric dermatology

authors： Fukuie T,Yasuoka R,Fujiyama T,Sakabe JI,Taguchi T,Tokura Y

更新日期：2019-03-01 00:00:00

abstract：:Discoid lupus erythematosus (DLE) is the most common variant of cutaneous chronic lupus erythematosus (CLE). Sun protection, topical corticosteroids, and antimalarials constitute the first-line options for treatment. In refractory cases, alternative antimalarials, methotrexate, retinoids, and thalidomide have been uti...

journal_title：Pediatric dermatology

authors： Tran B,Yazdani Abyaneh MA,Wu J

更新日期：2020-01-01 00:00:00

abstract：:We present the case of an 8-year-old girl who presented with distal extremity necrosis of the hands, feet, nose, and ears as an acute manifestation of cutaneous polyarteritis nodosa (CPAN). She was emergently managed with intravenous steroids, nifedipine, sildenafil, pentoxifylline, nitroglycerin paste, aspirin, low-m...

journal_title：Pediatric dermatology

authors： Williams VL,Guirola R,Flemming K,Modi GM,Rosales C,DeGuzman MM

更新日期：2012-07-01 00:00:00

abstract：:We report a case of congenital hypertrichosis and FOXN1 duplication. FOXN1 is a member of the forkhead box gene family, located on chromosome 17. Its function includes differentiation of epithelial cells and regulation of keratinocytes, especially hair keratins. Loss of function of these transcription factors leads to...

journal_title：Pediatric dermatology

authors： Gilhooley E,Gormally S,Irvine A,Lynch SA,Collins S

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND/OBJECTIVES:Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are medical emergencies. Mainstays of treatment include removal of the offending agent, supportive care, and wound care. The use of immunosuppressive agents such as corticosteroids and intravenous immunoglobulin (IVIg) is controve...

journal_title：Pediatric dermatology

authors： St John J,Ratushny V,Liu KJ,Bach DQ,Badri O,Gracey LE,Ho AW,Raff AB,Sugai DY,Schalock P,Kroshinsky D

更新日期：2017-09-01 00:00:00

abstract：:Hidradenitis suppurativa is a chronic relapsing disorder of follicular occlusion that is often recalcitrant to therapy. Topical and systemic antibiotics, hormonal therapies, oral retinoids, immunosuppressant agents, and surgical treatment are some of the therapeutic alternatives used for this often recalcitrant and fr...

journal_title：Pediatric dermatology

authors： Lam J,Krakowski AC,Friedlander SF

更新日期：2007-09-01 00:00:00

abstract：:Lindane (gamma benzene hexachloride) is a widely prescribed topical scabicide because of its efficacy and cost-effectiveness. Although toxicity from a single proper application of lindane is generally not observed, the hazards of repeated applications, industrial exposure, and accidental ingestion have been well docum...

journal_title：Pediatric dermatology

authors： Bhalla M,Thami GP

更新日期：2004-09-01 00:00:00

abstract：:Infantile myofibromatosis is a rare benign tumor of infancy and childhood that occurs in solitary, multiple, and generalized forms with similar histology but different clinicopathologic and prognostic implications. Even solitary tumors need follow-up, as the type of presentation will be determined over time. It is nec...

journal_title：Pediatric dermatology

authors： Jurcić V,Perković T,Pohar-Marinsek Z,Hvala A,Lazar I

更新日期：2003-07-01 00:00:00

abstract：:Congenital midline cervical cleft is a rare anomaly of the ventral neck that heretofore has not been reported in the dermatology literature. We present a case of a midline cervical cleft that was diagnosed and managed at an early age. We also review the literature and discuss its clinical and histologic features, trea...

journal_title：Pediatric dermatology

authors： Eastlack JP,Howard RM,Frieden IJ

更新日期：2000-03-01 00:00:00

abstract：:Lipoblastoma is a rare neoplasm of embryonal adipose tissue most often encountered on the trunk and extremities of children. It commonly presents as a painless subcutaneous soft tissue mass, but there are other unique clinical presentations that are important to recognize. The differential is broad and includes sarcom...

journal_title：Pediatric dermatology

authors： Shen LY,Amin SM,Chamlin SL,Mancini AJ

更新日期：2017-03-01 00:00:00

abstract：:Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP) is an autosomal dominant inherited blistering skin disease characterized by nonscarring blistering and reticulated hyperpigmentation. It is most commonly due to a heterozygous point mutation, P25L, in the nonhelical V1 domain of keratin 5 (KRT5). Here we...

journal_title：Pediatric dermatology

authors： Geller L,Kristal L,Morel KD

更新日期：2013-09-01 00:00:00

abstract：:Familial cold auto-inflammatory syndrome, Muckle-Wells syndrome and chronic infantile neurologic, cutaneous, articular syndrome are related disorders associated with mutations in the CIAS1 gene. They appear to represent a continuum of one disease characterized by IL-1-mediated inflammation. Until recently, these condi...

journal_title：Pediatric dermatology

authors： O'Connell SM,O'Regan GM,Bolger T,Hoffman HM,Cant A,Irvine AD,Watson RM

更新日期：2007-01-01 00:00:00

abstract：:We report a 5-month-old girl diagnosed with bullous pemphigoid who initially did not respond to systemic corticosteroids and dapsone but rapidly improved after the addition of intravenous immunoglobulin (IVIG) infusions. A literature search revealed anecdotal cases of infantile bullous pemphigoid treated with IVIG, al...

journal_title：Pediatric dermatology

authors： Tekin B,Yücelten AD

更新日期：2015-09-01 00:00:00

abstract：:Verrucous perforating collagenoma is an extremely rare variant of acquired perforating dermatosis that has been seldom described in literature. We present the case of an 18-month-old boy who presented with an erythematous plaque with a central keratotic plug on the leg. Histopathology revealed transepidermal eliminati...

journal_title：Pediatric dermatology

authors： Aizman L,Gelman A,Marathe K

更新日期：2019-09-01 00:00:00

abstract：:Woolly hair nevus is a rare syndrome that presents as woolly hair in restricted areas of the scalp and may be associated with pigmented macules or epidermal nevus on the body. Here, we report a case of woolly hair nevus, linear pigmentation, and multiple epidermal nevi with a somatic HRAS c.34G>A(p.G12S) mutation. ...

journal_title：Pediatric dermatology

authors： Nishihara K,Tohyama M,Kubo A

更新日期：2019-05-01 00:00:00

abstract：:Scurvy, or hypovitaminosis C, is an uncommon condition that exists today primarily within certain unique populations-particularly the elderly subjects, patients with neurodevelopmental disabilities or psychiatric illnesses, or others with unusual dietary habits. Vitamin C is an essential nutrient in the human body, an...

journal_title：Pediatric dermatology

authors： Cole JA,Warthan MM,Hirano SA,Gowen CW Jr,Williams JV

更新日期：2011-07-01 00:00:00

abstract：:Trichothiodystrophy (TTD) is a hair abnormality that may be associated with a large number of alterations affecting the skin phenotype and skin appendages, nervous system, eyes, bones, and immune, gonadal, and endocrine systems. We report the first case of TTD associated with a urologic malformation and primary hyperc...

journal_title：Pediatric dermatology

authors： Malvehy J,Ferrando J,Soler J,Tuneu A,Ballesta F,Estrach T

更新日期：1997-11-01 00:00:00

abstract：:We observed 5387 infants over 10 years in weekly visits to a neonatal ward and obtained the following frequency data on these skin changes: erythema toxicum neonatorum, 40.8%; perianal dermatitis, 18.9%; scrotal pigmentation, 15.2%; miliaria, 8.5%; and adnexal polyp of neonatal skin, 4.1%. The frequencies of the types...

journal_title：Pediatric dermatology

authors： Hidano A,Purwoko R,Jitsukawa K

更新日期：1986-02-01 00:00:00

abstract：:Post-transplantation lymphoproliferative disorder (PTLD) is one of the most common de novo malignancies in patients who receive immunosuppressive therapy after solid organ transplantation. We report a case of a 5-year-old girl who presented with indurated violaceous skin nodules 3.5 years post-liver transplantation, d...

journal_title：Pediatric dermatology

authors： Chen KY,Lin CY,Kuo TT,Shih LY,Chang CH,Chen WT,Yang CY

更新日期：2019-09-01 00:00:00

abstract：:Graft-versus-host disease (GVHD) is an underappreciated complication of autologous hematopoietic stem cell transplantation (AHSCT) that can affect the skin, gastrointestinal tract, and liver. The development of this rare condition is probably due to an impairment of immunologic tolerance that can occur spontaneously t...

journal_title：Pediatric dermatology

authors： Kaffenberger J,Basak SA,Ioffreda M

更新日期：2015-03-01 00:00:00