Abstract:
:Nitric oxide is a potent endogenous vasodilator involved in the homeostatic control of systemic blood pressure. It has also recently been demonstrated that when inhaled in low concentrations it acts as a specific pulmonary vasodilator. The concept of inhaled nitric oxide as a form of therapy is almost an anathema to anaesthetists. However, nitric oxide is being used increasingly for the treatment of persistent pulmonary hypertension of the neonate and in the adult respiratory distress syndrome. One major limitation to its frequent and widespread use is the problem of measuring the concentration of nitric oxide delivered. Currently, the gold standard technique used is chemiluminesence. However, the equipment required is costly and can be difficult to use. If the use of inhaled nitric oxide increases and it develops a therapeutic role then its applications may be limited only to centres which can afford such equipment. Others may be prevented from using a potentially valuable therapy due to lack of a controlled delivery system for nitric oxide. An inexpensive, simple alternative technique to chemiluminesence is described, which will allow most intensive care units the freedom to use inhaled nitric oxide if necessary.
journal_name
Anaesthesiajournal_title
Anaesthesiaauthors
Petros AJ,Cox P,Bohn Ddoi
10.1111/j.1365-2044.1994.tb14183.xsubject
Has Abstractpub_date
1994-04-01 00:00:00pages
317-9issue
4eissn
0003-2409issn
1365-2044journal_volume
49pub_type
杂志文章相关文献
ANAESTHESIA文献大全abstract::We have compared the performance of the Baxter disposable with the Graseby electronic patient-controlled analgesia system in 30 patients following major gynaecological surgery. Patients were allocated randomly to receive analgesia via the Baxter or Graseby device for postoperative pain relief. There were no significan...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1365-2044.1992.tb02020.x
更新日期:1992-02-01 00:00:00
abstract::We conducted a randomised controlled trial to compare the efficacy of forced-air warming (Bair Hugger(trade mark), Augustine Medical model 500/OR, Prairie, MN) with that of an electric heating pad (Operatherm 202, KanMed, Sweden) for maintenance of intra-operative body temperature in 60 patients undergoing total knee ...
journal_title:Anaesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1365-2044.2006.04816.x
更新日期:2006-11-01 00:00:00
abstract::Subclinical renal dysfunction is thought to occur as a systemic manifestation of ischaemia-reperfusion injury of other organs. Liver transplantation is associated with major ischaemia-reperfusion injury. Thirty-four patients undergoing elective liver transplantation were randomly allocated to receive either saline or ...
journal_title:Anaesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1365-2044.2006.04532.x
更新日期:2006-03-01 00:00:00
abstract::To assess the potential for atmospheric nitrogen to enter the nonventilated lung following the initiation of single-lung ventilation, the nonventilated lung of 10 patients undergoing video-assisted thoracoscopy was connected to the air in a water-filled spirometer, and gas movement out of and back into the lung was me...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1046/j.1365-2044.1999.00845.x
更新日期:1999-05-01 00:00:00
abstract::We compared the predictive performance of the existing Diprifusor and Schnider models, used for target-controlled infusion of propofol, with a new modification of the Diprifusor model (White) incorporating age and sex covariates. The bias and inaccuracy (precision) of each model were determined using computer simulati...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/anae.12631
更新日期:2014-06-01 00:00:00
abstract::Forty-seven children aged between four and 11 years received temazepam 0.5 mg/kg in a novel fast dispensing dosage form. The preparation was well accepted and associated with few side-effects. Satisfactory sedation and anxiolysis was obtained in over 93% of patients. The relative merits of a variety of routes of admin...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1985.tb10792.x
更新日期:1985-04-01 00:00:00
abstract::Harold King was an analytical chemist of distinction, who worked with Sir Henry Dale and his colleagues in the Medical Research Institute, later the Medical Research Council. He helped to quash the theory that the anaesthetic action of ether was attributable to its impurities. Interest in alkaloids led to the elucidat...
journal_title:Anaesthesia
pub_type: 传,历史文章,杂志文章
doi:10.1111/j.1365-2044.1991.tb09723.x
更新日期:1991-08-01 00:00:00
abstract::Propofol has been shown to cause pain on injection. This study investigated the effect of warming propofol to 37 degrees C on the pain of intravenous injection. One hundred and one women on outpatient gynaecology lists were allocated to receive propofol either at room temperature or at 37 degrees C. Warming propofol d...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1365-2044.1996.tb07802.x
更新日期:1996-05-01 00:00:00
abstract::Colorimetric carbon dioxide indicators are designed for the verification of satisfactory tracheal tube placement. However, widespread use of the device in this and other applications is hampered by limitations in its performance characteristics. A new colorimetric breath indicator (Colibri) has been developed that ove...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:
更新日期:1994-09-01 00:00:00
abstract::An account of plasma cholinesterase activity in samples of maternal and cord blood is presented. It is confirmed that plasma exchange markedly reduces the level of activity in maternal blood, and that the level is further reduced during the first 3-4 postnatal days. A particularly marked decrease was found in those ca...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1988.tb05423.x
更新日期:1988-01-01 00:00:00
abstract::The organisational state of inpatient pain management in UK hospitals is difficult to determine. We sent an electronic questionnaire to 209 acute pain service leads throughout the UK. Questions were about staffing and service provision. We received 141 responses (67%); 47% of all UK hospitals. Each service was respons...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/anae.14007
更新日期:2017-10-01 00:00:00
abstract::A case is presented of a mother with unanticipated profound thrombocytopenia who received a continuous epidural anaesthetic for labour. No neurological sequelae or excessive bleeding occurred. It is clear, after a review of the literature, that more information is needed to define the lower limits of platelet count at...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1989.tb09270.x
更新日期:1989-09-01 00:00:00
abstract::In this, the second of two articles covering specific medical emergencies, we discuss the definitions, epidemiology, pathophysiology, acute and chronic management of pulmonary embolus and acute severe asthma. ...
journal_title:Anaesthesia
pub_type: 杂志文章,评审
doi:10.1111/anae.12051
更新日期:2013-01-01 00:00:00
abstract::The aim of this study was to compare conventional laryngeal mask airway sizing by weight with sizing by age in over- or underweight children. We studied 26 overweight (body mass index > 85th centile) and 26 underweight (body mass index < 15th centile) children. After general anaesthesia was induced, laryngeal mask air...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.2009.06160.x
更新日期:2010-01-01 00:00:00
abstract::In this study, we measured the performance of medical students and anaesthetists using a new tracker needle during simulated sciatic nerve block on soft embalmed cadavers. The tracker needle incorporates a piezo element near its tip that generates an electrical signal in response to insonation. A circle, superimposed ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/anae.15211
更新日期:2021-02-01 00:00:00
abstract::Routine pre-operative chest X-rays have been taken for 22 years. There has been recent criticism of this investigation. 1000 such X-rays taken in 1977 are compared with the same number in 1955. It appears now that routine pre-operative chest X-rays are not necessary under 30 years of age but that they are essential ov...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1978.tb08334.x
更新日期:1978-11-01 00:00:00
abstract::Intra-ocular pressure was measured before and throughout airway establishment with either the laryngeal mask airway or tracheal tube. Similar measurements were made on removal of either airway and the amount of coughing noted in the first minute after removal. There was a significantly smaller increase in intra-ocular...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1991.tb09847.x
更新日期:1991-11-01 00:00:00
abstract::A 34-year-old female patient developed methaemoglobinaemia following a femoral nerve block using prilocaine. The concentrations of methaemoglobin in the blood of the next eight patients receiving this block were assayed, and found to be significantly increased above baseline concentrations, but very significantly less...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1992.tb04212.x
更新日期:1992-12-01 00:00:00
abstract::We describe the administration of anaesthesia to a patient with Angelman syndrome, which is characterised by an abnormality of chromosome 15, where a subunit of the GABA receptor is coded. This has far-reaching anaesthetic implications as many drugs used in anaesthesia are thought to act via GABA receptors. Our patien...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.2008.05439.x
更新日期:2008-06-01 00:00:00
abstract::Twelve patients had their arterial oxygen saturation measured pre-operatively and on days 1, 4 and 7 after laparotomy. Measurements were performed in the supine, sitting and standing positions on each day. Arterial oxygen saturation was significantly higher during sitting and standing on days 1 and 4 after operation c...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1996.tb13637.x
更新日期:1996-03-01 00:00:00
abstract::Two cases of unexpected high spinal anaesthesia following failed extradural anaesthesia for Caesarean section are described. In both cases rapid and unexpected advance of blockade, after the subarachnoid injection of moderate doses of local anaesthetic, required tracheal intubation. In one of the cases 15 ml of 0.9% s...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1992.tb02393.x
更新日期:1992-08-01 00:00:00
abstract::The Acquired Immune Deficiency Syndrome (AIDS) is a group of conditions which is reaching epidemic proportions. It is caused by a virus new to man, with an as yet poorly understood natural history, ominous prognosis and no known cure. Anaesthetists should be aware of the implications of dealing with increasing numbers...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1986.tb12743.x
更新日期:1986-10-01 00:00:00
abstract::A debate has emerged in recently published studies about the optimum cardiopulmonary bypass temperature for good neurological outcome - warm vs. cold, i.e. normothermic vs. hypothermic. Although many comparative studies have been performed, the results of these studies are inconclusive and are difficult to interpret. ...
journal_title:Anaesthesia
pub_type: 杂志文章,评审
doi:10.1111/j.1365-2044.2005.04112.x
更新日期:2005-04-01 00:00:00
abstract::The Reverend Doctor Robert Laws (1851-1934) followed in the footsteps of David Livingstone to Central Africa. At the beginning of a long and distinguished career as a medical missionary in Christian service to the country that has since become the Republic of Malawi, he was a prime mover in the setting up of a mission...
journal_title:Anaesthesia
pub_type: 传,历史文章,杂志文章
doi:10.1111/j.1365-2044.1985.tb10611.x
更新日期:1985-11-01 00:00:00
abstract::Heat and moisture exchangers (HMEs) humidify, warm and filter inspired gas, protecting patients and apparatus during anaesthesia. Their incorporation into paediatric anaesthetic breathing systems is recommended. We experienced delays in inhalational induction whilst using a Mapleson F breathing system with an HME. We ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1046/j.1365-2044.2000.01521.x
更新日期:2000-06-01 00:00:00
abstract::This is a review of glycopyrrolate whose function in clinical practice is compared with that of atropine. ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1983.tb12525.x
更新日期:1983-12-01 00:00:00
abstract::Although bedside screening tests are routinely used to identify people at high risk of having a difficult airway, their clinical utility is unclear. We estimated the diagnostic accuracy of commonly used bedside examination tests for assessing the airway in adult patients without apparent anatomical abnormalities sched...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/anae.14608
更新日期:2019-07-01 00:00:00
abstract::The effects of two H2-receptor antagonists, famotidine and cimetidine, on the plasma levels of epidurally administered lignocaine were studied. Group A (n = 20) received famotidine 20 mg orally the night before surgery and 20 mg intramuscularly 60 minutes before induction of anaesthesia. Group B (n = 15) received cime...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章
doi:10.1111/j.1365-2044.1990.tb14437.x
更新日期:1990-09-01 00:00:00
abstract::In the UK, tranexamic acid is recommended for all surgical procedures where expected blood loss exceeds 500 ml. However, the optimal dose, route and timing of administration are not known. This study aimed to evaluate current practice of peri-operative tranexamic acid administration. Patients undergoing primary total ...
journal_title:Anaesthesia
pub_type: 杂志文章,多中心研究
doi:10.1111/anae.15056
更新日期:2020-08-01 00:00:00
abstract::This study was designed to compare the tracheal intubating conditions during a rapid sequence induction of anaesthesia using rocuronium 0.6 (n = 61) or 1.0 mg.kg-1 (n = 130) or suxamethonium 1.0 mg.kg-1 (n = 127) as the neuromuscular blocking drugs. Anaesthesia was induced with fentanyl 1-2 micrograms.kg-1 and thiopen...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1046/j.1365-2044.1998.00342.x
更新日期:1998-09-01 00:00:00