Growth factors in urologic tissues: detection, characterization, and clinical applications.

Abstract:

:During the last two decades, enormous strides have been made in understanding cellular and molecular biology. The direction of treatment of many neoplasms and other diseases are starting at the microscopic level. Growth factors are polypeptides that play a part in the development and maintenance of living tissues. We, as well as others, have investigated the role that growth factors play particularly in urologic tissues, both benign and malignant. We review several well-known growth factors and their function in prostate, kidney, and bladder tissues, as well as their functions in other regulating processes of the human body, and also the use of growth factors as tumor markers, and antibodies to growth factors as possible treatment of disease.

journal_name

Urology

journal_title

Urology

authors

Mydlo JH,Macchia RJ

doi

10.1016/0090-4295(92)90400-q

subject

Has Abstract

pub_date

1992-12-01 00:00:00

pages

491-8

issue

6

eissn

0090-4295

issn

1527-9995

pii

0090-4295(92)90400-Q

journal_volume

40

pub_type

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