Bacteriobilia in percutaneous transhepatic biliary drainage: occurrence over time and clinical sequelae. A prospective observational study.

Abstract:

BACKGROUND:In the diagnosis and treatment of biliary disorders, establishing percutaneous transhepatic biliary drainage (PTBD) is an invasive procedure that can potentially lead to infectious complications in both the short and long-term. We therefore prospectively analysed the time course and spectrum of biliary bacteria in patients undergoing PTBD. METHODS:Forty-nine patients (19 F, 30 M; mean age 64 years) with malignant (65%) or benign (35%) biliary disorders were included, 20 of whom had a newly established PTBD (group A), while the remaining 29 had already had their PTBD in situ (group B) for a mean of 8 months. Bacteriological analyses of bile and blood were carried out, and clinical symptoms and laboratory values were obtained. RESULTS:Biliary bacteria were found in 60% of cases during the initial PTBD placement, and 24 h later this rate had already increased to 85%; two or more microorganisms were found in 40% initially and in 70% after a few days. At later PTBD exchanges, bacteriobilia was found in 100%, with all patients harbouring multiple organisms. Whereas the initial spectrum was mixed, Escherichia coli and enterococci (97% each), Klebsiella (73%) and Bacteroides species (37%) later predominated; Candida increased initially from 15% to 80%, but later decreased to 30%. Clinical signs of cholangitis were observed in 30% initially (no sepsis), but decreased to 6% at later exchanges. CONCLUSIONS:Bacteriobilia is initially a frequent, and later a regular, event in PTBD; however, clinically significant complications are rare during the long-term course and limited to the initial, more invasive, phase of PTBD. A knowledge of the bacterial spectrum is important for selecting appropriate antibiotic coverage if complications arise and/or major interventions such as surgery are planned.

journal_name

Scand J Gastroenterol

authors

Rösch T,Triptrap A,Born P,Ott R,Weigert N,Frimberger E,Allescher HD,Classen M,Kamereck K

doi

10.1080/00365520310003549

subject

Has Abstract

pub_date

2003-11-01 00:00:00

pages

1162-8

issue

11

eissn

0036-5521

issn

1502-7708

journal_volume

38

pub_type

杂志文章
  • Effect of pancreatic enzymes in non-ulcer dyspepsia. A pilot study.

    abstract::The symptomatic effect of pancreatic enzymes was examined in 37 patients with non-ulcer dyspepsia (NUD) recruited from general practice by means of a 24-day multicrossover model (MCOM) including six treatment periods and five regular interchanges between pancreatic enzymes and placebo. The evaluation was based on a co...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章

    doi:

    authors: Kleveland PM,Johannessen T,Kristensen P,Løge I,Sandbakken P,Dybdahl J,Petersen H

    更新日期:1990-03-01 00:00:00

  • The diagnostic value of colonoscopy compared with rectosigmoidoscopy in children and adolescents with symptoms of chronic inflammatory bowel disease of the colon.

    abstract::Seventy-eight young patients with symptoms of chronic inflammatory bowel disease (IBD) of the colon have been investigated to determine to what degree colonoscopy adds important information for the diagnosis of IBD in addition to results of the routine procedures, including rectosigmoidoscopy carried out at the same t...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528809093915

    authors: Holmquist L,Rudic N,Ahren C,Fällström SP

    更新日期:1988-06-01 00:00:00

  • Pre-endoscopic medication. A randomized double-blind trial of atropine and meperidine as a supplement to diazepam.

    abstract::The effects of an intramuscular injection of atropine (0.6 mg) and meperidine (1 mg/kg body weight) 30 min before topical benzocaine and intravenous diazepam administration were compared with those of a control group that received only benzocaine and intravenous diazepam in a randomized double-blind controlled trial o...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/00365527909181948

    authors: Schwartz SE,Fazio TL

    更新日期:1979-01-01 00:00:00

  • A 24-year controlled follow-up of patients with silent gallstones showed no long-term risk of symptoms or adverse events leading to cholecystectomy.

    abstract:BACKGROUND:The fate of asymptomatic gallstones has not been investigated in many studies with a long-term follow-up. We wanted to examine the subsequent rate of cholecystectomy and gallstone-related symptoms in a population examined in 1983. METHODS:Among the persons examined in 1983, unknown (perceived as silent) gal...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521.2011.571710

    authors: Schmidt M,Hausken T,Glambek I,Schleer C,Eide GE,Søndenaa K

    更新日期:2011-07-01 00:00:00

  • The chemotactic function of neutrophils in ulcerative colitis.

    abstract::Neutrophil chemotactic function was investigated in 30 patients with ulcerative colitis (UC) in an active (no. = 15) or an inactive (no. = 15) stage. Peripheral blood neutrophils from active cases had a significantly decreased stimulated migration in modified Boyden chambers. Simultaneously done investigations of neut...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528209182250

    authors: Elmgreen J,Binder V

    更新日期:1982-06-01 00:00:00

  • The role of mitochondrial folate enzyme MTHFD1L in esophageal squamous cell carcinoma.

    abstract:OBJECTIVE:The lack of novel therapeutic targets poses the major challenge to prolong survival and improve the quality of life for esophageal squamous cell carcinoma (ESCC). Methylenetetrahydrofolate dehydrogenase 1-like (MTHFD1L) plays critical roles in folate cycle maintenance. However, little information is available...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2017.1407440

    authors: Yang YS,Yuan Y,Hu WP,Shang QX,Chen LQ

    更新日期:2018-05-01 00:00:00

  • Availability of energy substrates during liver regeneration in malnourished rats.

    abstract::A retarded liver regeneration rate during malnutrition has previously been reported. To explore the mechanisms, some energy substrates were studied during liver regeneration and malnutrition. Forty-one rats were allocated to one of three groups (G): GI were normally nourished rats, which were partially hepatectomized;...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529108998607

    authors: Skullman S,Ihse I,Larsson J

    更新日期:1991-11-01 00:00:00

  • Epidemiology and causes of death in a Swedish cohort of patients with autoimmune hepatitis.

    abstract:BACKGROUND:Epidemiological studies of autoimmune hepatitis (AIH) show varying figures on prevalence and incidence, and data on the long-term prognosis are scarce. Objective To investigate the epidemiology, long-term prognosis and causes of death in a Swedish AIH cohort. MATERIAL AND METHODS:Data collected from 634 AIH...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2017.1335772

    authors: Danielsson Borssén Å,Marschall HU,Bergquist A,Rorsman F,Weiland O,Kechagias S,Nyhlin N,Verbaan H,Nilsson E,Werner M

    更新日期:2017-09-01 00:00:00

  • Necessity of multiple gastric biopsies from different sites for detection of clarithromycin-resistant Helicobacter pylori strains.

    abstract:BACKGROUND:It has been reported that approximately 10% of patients infected with Helicobacter pylori have both clarithromycin-susceptible and clathromycin-resistant strains. However, there have been no reports indicating whether only one gastric biopsy is sufficient to detect clarithromycin-resistant strains. METHODS:...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520310004731

    authors: Masuda H,Hiyama T,Yoshihara M,Tanaka S,Shimamoto F,Haruma K,Chayama K

    更新日期:2003-09-01 00:00:00

  • Gastrointestinal transit of amoxicillin modified-release tablets and a placebo tablet including pharmacokinetic assessments of amoxicillin.

    abstract:BACKGROUND:We have investigated the gastrointestinal transit time of, the influence of food intake on, the disintegration of, and the pharmacokinetics of amoxicillin in a modified-release form. METHODS:Radiolabelled modified-release tablets of amoxicillin and placebo tablets were administered, in an open three-way, ra...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/00365529609031626

    authors: Gottfries J,Svenheden A,Alpsten M,Bake B,Larsson A,Idström JP

    更新日期:1996-01-01 00:00:00

  • Health literacy levels in outpatients with liver cirrhosis.

    abstract:OBJECTIVE:Health literacy (HL) is a concept covering a range of cognitive and social skills that comprises aspects necessary for patients to navigate in the healthcare system. Our study aimed to investigate HL in patients with liver cirrhosis and determine factors associated with low HL. METHODS:Data were collected am...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2018.1545045

    authors: Freundlich Grydgaard M,Bager P

    更新日期:2018-12-01 00:00:00

  • TOP1 gene copy numbers are increased in cancers of the bile duct and pancreas.

    abstract:BACKGROUND:Bile duct and pancreatic cancer (PC) have poor prognoses and treatment options for inoperable patients are scarce. In order to improve outcome for these patients, there is an urgent need for biomarkers predictive of treatment effect. Irinotecan is a topoisomerase 1 (Top1) poison. Top1 protein, TOP1 gene copy...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521.2014.980318

    authors: Grunnet M,Calatayud D,Schultz NA,Hasselby JP,Mau-Sørensen M,Brünner N,Stenvang J

    更新日期:2015-04-01 00:00:00

  • Helicobacter pylori DNA isolation in the stool: an essential pre-requisite for bacterial noninvasive molecular analysis.

    abstract:PURPOSE:Real-time polymerase chain reaction (RT-PCR) is a widely used technique for bacterial and viral infection diagnosis. Herein, we report our preliminary experience in retrieving H. pylori genetic sequences in stools and analyzing genotypic clarithromycin resistance by RT-PCR (noninvasive), with the aim of compari...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2016.1216592

    authors: Giorgio F,Ierardi E,Sorrentino C,Principi M,Barone M,Losurdo G,Iannone A,Giangaspero A,Monno R,Di Leo A

    更新日期:2016-12-01 00:00:00

  • A socio-economic study of patients with ulcerative colitis.

    abstract::A material is presented of 222 patients with ulcerative colitis, who on admission to hospital during the 5-year period 1960-65 were permanent residents in the county district of Copenhagen or the municipality of Gentofte, the population of which was used as a control material. This material was divided into 21 socio-e...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365526709180058

    authors: Bonnevie O

    更新日期:1967-01-01 00:00:00

  • Chronic non-A, non-B hepatitis. A long-term follow-up study in 49 patients.

    abstract::Forty-nine patients with biopsy-verified chronic non-A, non-B hepatitis (NANBH) of both percutaneously transmitted and sporadic types were followed up for up to 20 years (mean, 62 months +/- 44 months). Drug addicts were not included. Twenty-four patients had chronic persistent hepatitis (CPH), and 25 had chronic acti...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528708991968

    authors: Wejstål R,Lindberg J,Lundin P,Norkrans G

    更新日期:1987-11-01 00:00:00

  • Expression of hepatocyte growth factor and c-met receptor in gastric mucosa during gastric ulcer healing.

    abstract:BACKGROUND:Recent studies have shown that hepatocyte growth factor (HGF) has a mitogenic and motogenic activity for gastric mucosal cells. The aim of this study is to ascertain the clinical significance of the expression of HGF and its receptor (c-met) during the course of gastric ulcer healing. METHODS:Ten patients w...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/003655200750024489

    authors: Hori K,Shiota G,Kawasaki H

    更新日期:2000-01-01 00:00:00

  • A snare combined with endoclips to assist in endoscopic submucosal dissection for intraepithelial neoplasia in the entire colon and rectum.

    abstract:OBJECTIVE:The use of mucosal traction to assist in colonic and rectal endoscopic submucosal dissection (ESD), especially for deep colonic ESD, is challenging. We developed a method of inverse insertion of a snare into the endoscopic working channel to deliver it into the colon together with the endoscope. With this met...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2018.1549270

    authors: Zhang Q,Xing TY,Wang Z

    更新日期:2019-01-01 00:00:00

  • Autoimmune chronic active hepatitis: changing reactivity for antibodies to hepatitis C virus after immunosuppressive treatment.

    abstract::Thirty-three patients fulfilling stringent criteria for autoimmune chronic active hepatitis (CAH) were tested for antibodies against hepatitis C virus (anti-HCV) with an enzyme immunoassay. Eleven of the 33 (33%) patients were anti-HCV-reactive in a serum drawn before initiation of immunosuppressive therapy. Anti-HCV-...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529008998551

    authors: Schvarcz R,von Sydow M,Weiland O

    更新日期:1990-11-01 00:00:00

  • Role of anti-parietal cell antibody in Helicobacter pylori-associated atrophic gastritis: evaluation in a country of high prevalence of atrophic gastritis.

    abstract:BACKGROUND:Helicobacter pylori plays an important part in the progression of atrophic gastritis; however, markers for predicting the progression of atrophic gastritis remain unidentified. We investigated the relation between the degree of atrophic gastritis and the amount of anti-parietal cell antibodies (APCAs) presen...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/003655202317284183

    authors: Ito M,Haruma K,Kaya S,Kamada T,Kim S,Sasaki A,Sumii M,Tanaka S,Yoshihara M,Chayama K

    更新日期:2002-03-01 00:00:00

  • A prospective reappraisal of emergency endoscopy in patients with portal hypertension.

    abstract::In a prospective study of emergency endoscopy in patients with portal hypertension and oesophageal varices referred to King's College Hospital with acute upper gastrointestinal bleeding, initial endoscopic examination on 90 separate consecutive hospital admissions carried out within 24 h of clinical haemorrhage showed...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Mitchell KJ,MacDougall BR,Silk DB,Williams R

    更新日期:1982-11-01 00:00:00

  • Effectiveness of steroid therapy for pancreatic cysts complicating autoimmune pancreatitis and management strategy for cyst-related complications.

    abstract::Objectives: Autoimmune pancreatitis (AIP) sometimes becomes complicated with pancreatic cysts, although their detailed characteristics and management strategy have not been fully determined. We aimed to clarify the efficiency of steroid therapy and the risk factors for cyst formation and cyst-related complications. Me...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2019.1623307

    authors: Kuraishi Y,Watanabe T,Muraki T,Ashihara N,Ozawa M,Nakamura A,Kanai K,Hamano H,Kawa S

    更新日期:2019-06-01 00:00:00

  • Heterotopic gastric mucosa: a significant clinical entity.

    abstract:OBJECTIVE:Despite the apparent lack of clinical interest in the inlet patches of heterotopic gastric mucosa (HGM) in the upper esophagus, the literature contains reports of complications associated with HGM. The aim of this study was to determine the prevalence and clinical importance of HGM in patients referred for up...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520600763094

    authors: Baudet JS,Alarcón-Fernández O,Sánchez Del Río A,Aguirre-Jaime A,León-Gómez N

    更新日期:2006-12-01 00:00:00

  • High incidence of extrapancreatic carcinoma in chronic pancreatitis.

    abstract::In the prospective clinical long-term study of 246 patients with chronic pancreatitis, 26 patients (24 men) developed 27 histologically proved malignant tumors (11%). Four additional patients with neoplasia were excluded (papilloma, two; Bowen's disease of the tonsils, one; and seminoma, one, occurring 8 years before ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528009181490

    authors: Ammann RW,Knoblauch M,Möhr P,Deyhle P,Largiadèr F,Akovbiantz A,Schüler G,Schneider J

    更新日期:1980-01-01 00:00:00

  • Insulin-like growth factor-I partially attenuates colonic damage in rats with experimental colitis induced by oral dextran sulphate sodium.

    abstract:BACKGROUND:Administration of insulin-like growth factor-I (IGF-I) results in selective growth of the gastrointestinal tract. We investigated the effects of IGF-I on the colonic damage induced by oral dextran sulphate sodium (DSS) in the rat. METHODS:Rats consumed 2% DSS in the drinking water for 10 days to induce coli...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365529850166923

    authors: Howarth GS,Xian CJ,Read LC

    更新日期:1998-02-01 00:00:00

  • Pouch emptying of solid foods after gastroplasty for morbid obesity.

    abstract::To obtain information on possible determinants of weight loss after horizontal gastroplasty, pouch emptying was prospectively investigated in 27 morbidly obese patients. A scintigraphic method was used. Examinations were carried out every 6 months until 2 years after surgery. Pouch emptying was described by means of d...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528509089272

    authors: Andersen T,Pedersen BH,Henriksen JH,Uhrenholdt A

    更新日期:1985-12-01 00:00:00

  • Faecal calprotectin and lactoferrin as markers of acute radiation proctitis: a pilot study of eight stool markers.

    abstract:BACKGROUND:Non-invasive diagnostic tools to evaluate the severity of acute, radiation-induced proctitis are not readily available. The faecal excretion of eight markers of gut inflammation was therefore examined. Five proteins and three lipid derivates were analysed in sequential stool samples taken before and during r...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520410003614

    authors: Larsen A,Hovdenak N,Karlsdottir A,Wentzel-Larsen T,Dahl O,Fagerhol MK

    更新日期:2004-11-01 00:00:00

  • Endoscopic papillectomy and KRAS expression in the treatment of adenoma in the major duodenal papilla.

    abstract:OBJECTIVE:The use of endoscopic papillectomy for resecting adenomas in the major duodenal papilla is increasing. This study focuses on the following three issues: Can endoscopic papillectomy be performed as a safe diagnostic and/or therapeutic procedure in biopsy-verified or suspected ampullary adenoma? Does expression...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521.2015.1046912

    authors: Haraldsson E,Swahn F,Verbeke C,Mattsson JS,Enochsson L,Ung KA,Lundell L,Heuchel R,Löhr JM,Arnelo U

    更新日期:2015-01-01 00:00:00

  • Incidence and risk factors for post-ERCP pancreatitis in pancreas divisum patients without chronic pancreatitis.

    abstract::Aims: The studies on post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) in pancreas divisum (PD) patients without chronic pancreatitis (CP) are rare. In this study, we aimed to evaluate the incidence of PEP in PD patients without CP and the risk and protective factors for PEP.Methods: Consec...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2020.1774922

    authors: Meng QQ,Zhao SB,Wang ZJ,Shen Z,Xia T,Wang SL,Gu L,Pan P,Li ZS,Yao J,Shi YH,Bai Y

    更新日期:2020-06-01 00:00:00

  • Fasting levels of serum gastrin in different functional and morphologic states of the antrofundal mucosa. An analysis of 860 subjects.

    abstract::The relationship of fasting serum gastrin (FSG) levels to the histologic state of antral and body mucosa and to the stimulated acid output (PAO) was examined in 860 subjects. The FSG levels correlated with PAO and atrophy of the body mucosa: the FSG increased linearly with an increase in the grade of body atrophy and ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529009095523

    authors: Sipponen P,Valle J,Varis K,Kekki M,Ihamäki T,Siurala M

    更新日期:1990-05-01 00:00:00

  • Characteristics and risk factors for recurrence of nonalcoholic steatohepatitis following liver transplantation.

    abstract:OBJECTIVES:Nonalcoholic steatohepatitis (NASH), which is a common and increasing indication for liver transplantation (LT), is known to recur after LT. Since the recurrence of NASH can lead to graft failure, the identification of predictive factors is needed and preventive strategies should be implemented. METHODS:We ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2019.1577484

    authors: Tokodai K,Karadagi A,Kjaernet F,Romano A,Ericzon BG,Nowak G

    更新日期:2019-02-01 00:00:00