Abstract:
:Natural killer (NK) cells are highly influenced by physical exercise. The possible important mechanisms behind exercise-induced changes in NK cell function are cytokines, hyperthermia, and stress hormones, including catecholamines, growth hormone, cortisol, and beta-endorphins. Infusion studies mimicking stress hormone levels in blood during exercise indicate that increased plasma-adrenaline accounts for at least part of the exercise-induced modulation of NK cell function. During moderate as well as severe acute exercise, the NK cell activity is enhanced, but severe exercise is followed by immunodepression, at least in part caused by prostaglandins. Elite athletes have at rest elevated NK cell activity. However, due to frequent severe exercise the NK cell function is often temporarily severely depressed. It is suggested that during the time of immunodepression microorganisms, especially virus, invade the host, whereby infections can be established. However, in those who perform regular moderate exercise the immune system will often be temporarily enhanced and this will protect these from infections.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Pedersen BK,Ullum Hdoi
10.1249/00005768-199402000-00003subject
Has Abstractpub_date
1994-02-01 00:00:00pages
140-6issue
2eissn
0195-9131issn
1530-0315journal_volume
26pub_type
杂志文章,评审abstract::The degree of parasympathetic control of resting heart rate (PC) was assessed by measurement of variation in heart period (VHP) during cardiopulmonary synchronization of respiration. Respiratory period was arbitrarily preset and standardized at 7 heart beats (3 beats inspiration, 4 beats expiration). The mathematical ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/00005768-198508000-00008
更新日期:1985-08-01 00:00:00
abstract:PURPOSE:The aim of this study was to determine whether highly active antiretroviral therapy (HAART), rather than the direct effect of HIV infection, limits peripheral muscle oxygen extraction-utilization (a-vO(2)) in individuals infected with the human immunodeficiency virus (HIV). METHODS:Fifteen subjects (6 female a...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.MSS.0000074567.61400.93
更新日期:2003-07-01 00:00:00
abstract:PURPOSE:This study aimed to catalog the relationships between step-based accelerometer metrics indicative of physical activity volume (steps per day, adjusted to a pedometer scale), intensity (mean steps per minute from the highest, not necessarily consecutive, minutes in a day; peak 30-min cadence), and sedentary beha...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000001100
更新日期:2017-02-01 00:00:00
abstract:INTRODUCTION:Low lean mass (LM) is a risk factor for chronic disease, a major cause of disability and diminished quality of life, and is a heritable trait. However, relatively few specific genetic factors have been identified as potentially influencing this trait. METHODS:In this study, we selected 1493 single-nucleot...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000000889
更新日期:2016-07-01 00:00:00
abstract:PURPOSE:The purpose of study was to determine whether quadriceps/patella and Achilles tendon length and flexibility of the knee extensors and plantar flexors are related to walking and running economy. METHODS:Twenty-one male distance runners were subjects. Quadriceps/patella and Achilles tendon length were measured b...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e318210464a
更新日期:2011-08-01 00:00:00
abstract:PURPOSE:sarcopenia plays a principal role in the pathogenesis of frailty and functional impairment that occur with aging. There are few published accounts that examine the overall benefit of resistance exercise (RE) for lean body mass (LBM) while considering a continuum of dosage schemes and/or age ranges. Therefore, t...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,meta分析,评审
doi:10.1249/MSS.0b013e3181eb6265
更新日期:2011-02-01 00:00:00
abstract::The effects of the potent opioid, sufentanil, were studied in 11 athletes. Sufentanil was administered intravenously (up to 0.5 microgram.kg-1 over 10 min) to the subjects while they ran at 14 km.hr-1 on a level treadmill. Prior to, and after, the drug infusion, the treadmill was inclined by 6% for 4 min and CO2 was i...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1988-12-01 00:00:00
abstract::Psychophysical scaling of symptoms or discomfort during exercise testing has evolved as an important adjunct to the study of therapeutic interventions in heart disease. One of the major shortcomings of clinical exercise testing, however, has been the assessment of chest pain. Although the presence and characteristics ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:
更新日期:1994-09-01 00:00:00
abstract:PURPOSE:The goal of this trial was to determine whether low-load blood flow-restricted (BFR) exercise of appendicular muscles induces a cross-transfer of effect to the trunk extensor (TE) muscles, such that low-load TE exercise would enhance TE size and function to a greater extent than standard low-load exercise in pe...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0000000000001984
更新日期:2019-09-01 00:00:00
abstract:PURPOSE:To compare voluntary and electrically evoked knee extensor torque, surface electromyography (EMG), and activation level obtained under seated versus supine position, i.e., with shortened versus lengthened rectus femoris (RF) muscle. METHODS:The knee extensor torque obtained during maximal voluntary contraction...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.MSS.0000084426.03247.93
更新日期:2003-09-01 00:00:00
abstract::The relationship between VO2 and velocity of running (running economy) has been rather casually dealt with until very recently, and there still remains considerable disagreement as to the importance of this variable. Various factors which have been shown, or appear, to affect running economy include environment (tempe...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:
更新日期:1985-06-01 00:00:00
abstract:OBJECTIVE:To evaluate the effect of chronic moderate-intensity exercise upon the alterations of immune system cell function induced by energy restriction. METHODS:Forty male Wistar rats were randomly assigned to the following groups: sedentary animals fed ad libitum (SF, N = 10) or submitted to energy restriction (SER...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000147626.32295.38
更新日期:2004-12-01 00:00:00
abstract::To determine whether a 13C-bicarbonate, isotope dilution technique could be used to estimate relative changes in energy expenditure of leisure activities of short duration, we studied eight adolescents who performed the following activities: watching television (120 min); playing a stringed instrument (60 min plus 60 ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-199709000-00021
更新日期:1997-09-01 00:00:00
abstract::The present investigation was conducted to determine whether critical power (CP) assesses the ability to perform continuous aerobic exercise and to determine whether training-induced changes in aerobic endurance are reflected by changes in the slope, but not the y-intercept of the CP function. Twelve healthy, active, ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1992-11-01 00:00:00
abstract:PURPOSE:The range of variability between individuals of the same chronological age (CA) in somatic and biological maturity is large and especially accentuated around the adolescent growth spurt. Maturity assessment is an important consideration when dealing with adolescents, from both a research perspective and youth s...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200204000-00020
更新日期:2002-04-01 00:00:00
abstract:PURPOSE:In this study, we examined the effects of body position (from deep to high position) in slide boarding by well-trained cross-country skiers. The main hypothesis was that a deeper, more "crouched" position would lead to reduced air resistance and enhanced power production during explosive extension of the lower ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000227536.13175.52
更新日期:2006-08-01 00:00:00
abstract:PURPOSE:The aim of this study was to test whether a tidally ventilated homogeneous lung model can correctly describe arterial and end-tidal gas partial pressures and thus the difference in end-tidal and arterial gas partial pressures at rest and during exercise. METHODS:The implemented mathematical modeling described ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200204000-00010
更新日期:2002-04-01 00:00:00
abstract:PURPOSE:As adjuvant therapy for enhancing the effects of stimulants and thereby minimizing medication doses, we hypothesized that aerobic exercise might be an effective adjunctive therapy for enhancing the effects of methylphenidate on the clinical symptoms, cognitive function, and brain activity of adolescents with at...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0000000000000373
更新日期:2015-01-01 00:00:00
abstract:PURPOSE:To examine 1) relationships between adult PA at 35 yr and PA as a child, and 2) the influence of enhanced primary school physical education (physed+) and of parental PA upon the long-term tracking of PA in the offspring. METHODS:PA data from the 1970-1977 Trois-Rivieres Growth and Development Study, completed ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000145525.29140.3b
更新日期:2004-11-01 00:00:00
abstract:PURPOSE:Regular physical activity leads to a more favorable cardiovascular risk factor profile and a lower risk of developing incident coronary heart disease (CHD). These correlations suggest that higher levels of physical activity should also attenuate the presence and extent of coronary atherosclerosis. METHODS:Phys...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200202000-00008
更新日期:2002-02-01 00:00:00
abstract:PURPOSE:To compare the effects of different patterns of regular brisk walking on fitness, risk factors for cardiovascular disease, and psychological well-being in previously sedentary adults. METHODS:Twenty-one subjects (14 women), aged 44.5 +/- 6.1 yr (mean +/- SD) were randomly assigned to two different, 6-wk progra...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00005768-200209000-00011
更新日期:2002-09-01 00:00:00
abstract:PURPOSE:Maternal obesity is known to predispose the offspring to impaired glucose metabolism and obesity associated with low-grade inflammation and hypothalamic dysfunction. Because preventive approaches in this context are missing to date, we aimed to identify molecular mechanisms in the offspring that are affected by...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000000835
更新日期:2016-05-01 00:00:00
abstract:PURPOSE:Neural adaptations to strength training have long been recognized, but knowledge of mechanisms remains incomplete. Using novel techniques and a design which limited experimental bias, this study examined if 4 wk of strength training alters voluntary activation and corticospinal transmission. METHODS:Twenty-one...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0000000000001367
更新日期:2017-11-01 00:00:00
abstract:PURPOSE:The purpose of this study was to investigate the influence of different cycling cadences on metabolic and kinematic parameters during subsequent running. METHODS:Eight triathletes performed two incremental tests (running and cycling) to determine maximal oxygen uptake (VO2max) and ventilatory threshold (VT) va...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00005768-200203000-00022
更新日期:2002-03-01 00:00:00
abstract:PURPOSE:The present study was designed to develop and validate a prediction equation for peak oxygen consumption VO2peak) using a progressive treadmill test and to refine the current target HR exercise guidelines for pregnancy (PARmed-X for Pregnancy). METHODS:One hundred fifty-six women between 16 and 22 wk of gestat...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000228940.09411.9c
更新日期:2006-08-01 00:00:00
abstract:PURPOSE:High school cross-country runners have a high incidence of injury, particularly at the shin and knee. An increased step rate during running has been shown to reduce impact forces and loading of the lower extremity joints. The purpose of this prospective study was to examine step rate as a risk factor for injury...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000000890
更新日期:2016-07-01 00:00:00
abstract:INTRODUCTION:Chronic unimanual motor practice increases the motor output not only in the trained but also in the nonexercised homologous muscle in the opposite limb. We examined the hypothesis that adaptations in motor cortical excitability of the nontrained primary motor cortex (iM1) and in interhemispheric inhibition...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0b013e31820a94b8
更新日期:2011-07-01 00:00:00
abstract::The gravity-dependency and age-dependency of noradrenergic vasoconstrictor outflow to skeletal muscle (muscle sympathetic nerve activity; MSNA) in humans was analyzed by applying microneurography technique. The basal level of MSNA in the horizontally supine position increased with aging without significant changes in ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-199610000-00039
更新日期:1996-10-01 00:00:00
abstract:PURPOSE:Exercise has been well documented to exert a beneficial effect on cardiovascular health. The effective control of arterial pressure (BP) is essential from the standpoint of cardiovascular prevention. So far, no study has determined the long-term effect of regular training as a monotherapy on both BP at rest and...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章
doi:10.1249/01.MSS.0000106173.81966.90
更新日期:2004-01-01 00:00:00
abstract::To test whether strenuous exercise with and without caloric restriction alters LH secretion, and whether these changes are apparent in the immediate post-exercise period, LH pulse parameters were studied in four moderately trained eumenorrheic women over three successive menstrual cycles. Blood samples were obtained 5...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1995-10-01 00:00:00