Quantitative assessment of free-radical generation during ischemia and reperfusion in the isolated rabbit heart.

abstract：BACKGROUND:17 beta-Estradiol and phytoestrogens are known to have beneficial effects on the cardiovascular systems of women. The exact mechanisms for how estrogens and phytoestrogens influence the cardiovascular system are not yet understood in detail. OBJECTIVE:The objective of this study was to investigate whether 1...

journal_title：Coronary artery disease

authors： Finking G,Wohlfrom M,Lenz C,Wolkenhauer M,Eberle C,Hanke H

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVES:The long-term clinical impact of polymer-free sirolimus-eluting stents (PF-SES) in unselected patients undergoing percutaneous coronary intervention (PCI) still remains poorly investigated. We studied the long-term clinical impact of PF-SES in a large cohort of unselected patients receiving PCI therapy at tw...

journal_title：Coronary artery disease

authors： Sinha N,Rai H,Cassese S,Kumar S,Kapoor A,Kastrati A

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:The aim of this study was to compare the outcome for men and women with chest pain or other symptoms suggestive of acute myocardial infarction (AMI) and a normal ECG on admission. METHODS:All patients who presented to our emergency room over a 21-month period with chest pain or other symptoms suggestive of ...

journal_title：Coronary artery disease

authors： Karlson BW,Herlitz J

更新日期：1996-03-01 00:00:00

abstract：OBJECTIVE:Plasma nuclear and mitochondrial DNA (mtDNA) levels are altered in many diseases. However, it is not known whether they are also altered in acute myocardial infarction (AMI). In the present study, we examined plasma nuclear and mtDNA levels in the patients with AMI before and after a percutaneous coronary int...

journal_title：Coronary artery disease

authors： Wang L,Xie L,Zhang Q,Cai X,Tang Y,Wang L,Hang T,Liu J,Gong J

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Serum gamma-glutamyl transferase (GGT) activity, an enzyme responsible for the extracellular catabolism of antioxidant glutathione, may directly take part in atherogenesis and evolve as a potential biochemical risk indicator of cardiovascular morbidity and mortality. An important characteristic of coronary a...

journal_title：Coronary artery disease

authors： Sen N,Basar N,Maden O,Ozcan F,Ozlu MF,Gungor O,Turak O,Malcok O,Atak R,Demir AD,Balbay Y

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Although atherosclerosis is supposed to be responsible for more than 50% of coronary artery ectasia, the precise pathology of coronary artery ectasia is not clearly understood. A histopathological examination of ectatic segments has revealed mainly destruction of the media layer of the artery. In the present...

journal_title：Coronary artery disease

authors： Yetkin E,Acikgoz N,Aksoy Y,Bariskaner E,Sivri N,Akturk E,Turhan H,Kosar F,Cehreli S

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:To assess the incidence, clinical significance, and independent risk factors of stroke in patients with acute myocardial infarction (AMI) treated invasively. MATERIALS AND METHODS:We analyzed 2520 consecutive patients with AMI admitted between 2003 and 2007. Data on long-term follow-up were screened to iden...

journal_title：Coronary artery disease

authors： Podolecki TS,Lenarczyk RK,Kowalczyk JP,Mazurek MH,Swiątkowski AM,Chodór PK,Pruszkowska-Skrzep PI,Sędkowska AA,Poloński L,Kalarus ZF

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:We and others have demonstrated that administration of thrombolytic agents causes the generation of thrombosis-promoting agents. At present, we have studied whether formation in vivo of excessive amounts of plasmin is responsible for the activation of coagulation in patients treated with recombinant tissue-t...

journal_title：Coronary artery disease

authors： Gram J,Munkvad S,Leebeek FW,Kluft C,Jespersen J

更新日期：1993-04-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to clarify clinical and angiographical characteristics of acetylcholine (ACh)-induced spasm in the right and left coronary artery. METHODS AND RESULTS:We performed 557 consecutive procedures of spasm provocation tests of ACh from January 1991 to December 2000 in patients withou...

journal_title：Coronary artery disease

authors： Sueda S,Kohno H,Fukuda H,Inoue K,Suzuki J,Watanabe K,Ochi T,Uraoka T

更新日期：2002-06-01 00:00:00

abstract：:This study investigates a strategy of low-pressure stenting with concomitant anti-platelet treatment designed to prevent short- and long-term events after stenting. Ninety consecutive patients who underwent percutaneous transluminal coronary angioplasty with stenting using low-pressure stent deployment (mean 8.1 atmos...

journal_title：Coronary artery disease

authors： Cafri C,Weinstein JM,Gilutz H,Kobal S,Ilia R

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVE:Drug-coated balloon (DCB) angioplasty has emerged as an effective management strategy worldwide. In June 2016, DCB became available for the treatment of de novo small coronary lesions in Japan; however, there has been no multicenter analysis in a post-approval real-world clinical setting to date. The aim of t...

journal_title：Coronary artery disease

authors： Funayama N,Muratsubaki S,Kawahatsu K,Miyata M,Katou Y,Oikawa T

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:ABO blood groups have been associated with venous thromboembolism and arterial thrombosis. Although platelets play key roles in thrombogenesis, the relation between ABO groups and platelets is not well known and was investigated in this study. PATIENTS AND METHODS:ABO blood type information was retrospectiv...

journal_title：Coronary artery disease

authors： Timur AA,Barnard J,Murugesan G,Gandhi S,Bhatt DL,Kottke-Marchant K

更新日期：2019-01-01 00:00:00

abstract：:Radiofrequency ablation of complex cardiac arrhythmias has undergone significant evolution in the past decade, with the development of technology enabling better anatomic and electrophysiologic mapping of abnormal cardiac tissue. In this paper, we will discuss the role of pre-procedural and post-procedural multidetect...

journal_title：Coronary artery disease

authors： Lobel RM,Lustgarten DL,Spector PS

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) and anemia have been extensively studied in ST-elevation myocardial infarction (STEMI), yet the precise nature of their reciprocal relationship has not been elucidated in STEMI patients. METHODS:We performed a retrospective analysis of 2096 consecutive patients admitted for STEMI b...

journal_title：Coronary artery disease

authors： Merdler I,Loewenstein I,Zahler D,Levit D,Hochstadt A,Banai S,Gal-Oz A,Shacham Y

更新日期：2020-10-13 00:00:00

abstract：OBJECTIVE:To investigate the changes of inflammatory factors and hemostatic variable in plasma after a high-fat meal in normocholesterolemic patients with essential hypertension. METHODS:A total of 60 hypertensive patients were randomly assigned to accept a single high-fat meal (group 1, n=40) or not (group 2, n=20) i...

journal_title：Coronary artery disease

authors： Liu L,Zhao SP,Wen T,Zhou HN,Hu M,Li JX

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVE:To evaluate immediate changes in left ventricular wall motion in patients treated using Biosense direct myocardial revascularization laser system. METHODS:Regional wall motion in 10 patients undergoing catheter-based direct myocardial revascularization using a holmium:yttrium aluminium garnet laser was asses...

journal_title：Coronary artery disease

authors： Shiran A,Goldstein SA,Ellahham S,Leon MB,Kornowski R

更新日期：2000-06-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to describe the procedural characteristics, myocardial perfusion, and long-term outcomes in ST-elevation myocardial infarction patients with an ectatic infarct-related artery (IRA). PATIENTS AND METHODS:The retrospective analysis included 1270 consecutive ST-elevation myocardial inf...

journal_title：Coronary artery disease

authors： Popovic B,Agrinier N,Metzdorf PA,Camenzind E

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVES:We treated patients experiencing drug-eluting stent (DES) restenosis with plain old balloon angioplasty (POBA), implantation of the same type of DES [homogeneous drug-eluting stent (HOMO-DES)], or implantation of a different type of DES [heterogeneous drug-eluting stent (HETERO-DES)], and compared the effica...

journal_title：Coronary artery disease

authors： Nojima Y,Yasuoka Y,Kume K,Adachi H,Hattori S,Matsutera R,Kohama Y,Sasaki T

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate the safety and efficacy of the novel NovaCross microcatheter system in patients with ischemic heart disease due to coronary chronic total occlusions (CTO). METHODS:A total of 191 subjects between the ages of 25-80 years were recruited in 10 investigational sites. Each s...

journal_title：Coronary artery disease

authors： Walsh SJ,Dudek D,Bryniarski L,Nicholson W,Karmpaliotis D,Uretsky B,McEntegart M,Assali A,Knaapen P,Kornowski R,Spratt JC,Goodwin M,Hanratty CG

更新日期：2020-11-01 00:00:00

abstract：:The phenomenon of myocardial stunning has been observed in all animal species studied. The possible occurrence of myocardial stunning in man has been demonstrated after either regional ischemia (such as exercise-induced angina, vasospastic or unstable angina) or after global ischemia (i.e., after cardioplegic arrest d...

journal_title：Coronary artery disease

authors： Ambrosio G,Tritto I

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:P-selectin, an adhesion molecule of the selectin family, is expressed on the surface of activated thrombocytes by thrombin. The aim of the present study was to assess the predictive value of P-selectin (estimated by flow cytometric assay) for acute cardiac events in acute coronary syndrome. METHODS:The stud...

journal_title：Coronary artery disease

authors： Itoh T,Nakai K,Ono M,Hiramori K

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:Nitroglycerin (NTG) is known to increase the blood supply to the myocardium, and would thus increase the delivery of a perfusional tracer such as sestamibi (MIBI) to the tissue. The latter, in turn, would take up and concentrate the tracer to a greater extent than in basal conditions only if energy-dependent...

journal_title：Coronary artery disease

authors： Greco C,Tanzilli G,Ciavolella M,Sinatra R,Banci M,Schillaci O,Macrina F,Scopinaro F,Marino B,Campa PP

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:Although smoking is a risk factor for coronary atherosclerosis, the age-related impact on lesion characteristics and plaque instability remains unclear. PATIENTS AND METHODS:In ADAPT-DES, 780 patients with 916 culprit lesions were evaluated by preprocedural grayscale and virtual histology-intravascular ultr...

journal_title：Coronary artery disease

authors： Kang SJ,Mintz GS,Witzenbichler B,Metzger DC,Rinaldi MJ,Duffy PL,Weisz G,Stuckey TD,Brodie BR,Shimizu T,Litherland C,Kirtane AJ,Stone GW,Maehara A

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:An association between early repolarization and ventricular fibrillation has recently been reported in patients with vasospastic angina (VSA). However, no studies have clarified whether the presence of early repolarization can predict VSA. METHODS:Participants comprised 286 patients (136 males) with clinica...

journal_title：Coronary artery disease

authors： Ikeda H,Hasegawa K,Uzui H,Fukuoka Y,Shiomi Y,Tama N,Miyazaki S,Ishida K,Tada H

更新日期：2020-11-13 00:00:00

abstract：OBJECTIVES:This Perspective reviews the results of early and contemporary studies evaluating the safety and efficacy of coronary revascularization in patients with diabetes. It also addresses the implications of some of the data in the Bypass Angioplasty Revascularization Investigation in type 2 diabetes (BARI 2D) tria...

journal_title：Coronary artery disease

authors： Sobel BE

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to explore the individual effects of the CYP2C19 G681A polymorphism and omeprazole use and their interaction on clopidogrel responsiveness in acute coronary syndrome (ACS). The CYP2C19 G681A polymorphism and omeprazole use were both known for retarding the effects of clopidogrel unde...

journal_title：Coronary artery disease

authors： Jirungda S,Pussadhamma B,Komanasin N,Senthong V,Leuangwatthananon W

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Single or multiple brief periods of myocardial ischemic preconditioning (PC) limits ischemia- and reperfusion-induced arrhythmias. This study tested whether PC protects against ischemia/reperfusion-induced arrhythmias and, if so, whether the protective effect was mediated by the opening of ATP-sensitive (KAT...

journal_title：Coronary artery disease

authors： Lu H,Remeysen P,De Clerck F

更新日期：1993-07-01 00:00:00

abstract：OBJECTIVE:Electrocardiographic indices like maximum P-wave duration (P(max)) and P-wave dispersion (PD) can be used to detect patients with atrial conduction disorders, myocardial ischemia and those at risk for atrial fibrillation. Considering the diurnal variation of ischemia in patients with significant coronary lesi...

journal_title：Coronary artery disease

authors： Yíldírím N,Topaloglu S,Bozboga S,Ocal A,Saricam E

更新日期：2006-12-01 00:00:00

abstract：:Potentially hazardous short ischemic episodes increase the tolerance of myocardium to ischemia paradoxically. This condition decreases the infarct area markedly caused by a longer duration of coronary occlusion. This phenomenon is known as 'ischemic preconditioning' and its powerful cardioprotective effect has been sh...

journal_title：Coronary artery disease

authors： Evrengul H,Seleci D,Tanriverdi H,Kaftan A

更新日期：2006-05-01 00:00:00

abstract：AIMS:Compare the degree of acute vascular injury caused by a polymer-free, thin-strut drug-eluting stent (DES) to that caused by a bioresorbable polymer, thick-strut DES using optical coherence tomography (OCT). METHODS AND RESULTS:Fifty patients requiring nonurgent PCI were randomized to receive either a thin or a th...

journal_title：Coronary artery disease

authors： Vilchez-Tschischke JP,Salazar C,Gil-Romero J,Mori R,Nuñez-Gil I,Quirós A,Nombela L,Del Trigo M,Jimenez-Quevedo P,Salinas P,Escaned J,Macaya C,Gonzalo N

更新日期：2020-08-19 00:00:00