[Time to pregnancy and lead exposure].

Abstract:

OBJECTIVE:To determine the effects of lead exposure on the time elapsed to become pregnant. MATERIAL AND METHODS:The study population consisted of 142 women residing in Mexico City between 1997 and 2001, who were already participating in a study to evaluate effects of lead exposure on reproductive health. Measurements of lead in bone were performed when women were first admitted to the program. Information on lead exposure and other variables of interest was obtained through a questionnaire. Participants were followed up to assess the relationship between the time required to become pregnant and lead exposure. Statistical analysis consisted of Kaplan-Meier estimates and Cox proportional hazards models. RESULTS:Of the total number of women in the program, 42 got pregnant: 34 before the first year of follow-up, and 8 at a later date. The mean value for lead concentration in blood was 9.3 micrograms/dl. The mean values for lead concentration in patella and tibia were 16.0 y 11.0 micrograms Pb/g of bone, respectively. Survival analysis was performed and no differences were detected in blood lead levels and time to pregnancy in the first year. Nevertheless, in women with blood lead levels above 10.0 micrograms/dl, the likelihood of not achieving pregnancy was five times higher (95% confidence interval [CI] 0.05-0.56) after one year of follow-up compared with women with blood lead levels below 10.0 micrograms/dl. CONCLUSIONS:Exposure to high lead concentrations may be an important risk factor influencing the time period for a woman to get pregnant, especially in fertile women who have tried to get pregnant for more than a year. This paper is available too at: http://www.insp.mx/salud/index.html.

journal_name

Salud Publica Mex

journal_title

Salud publica de Mexico

authors

Guerra-Tamayo JL,Hernández-Cadena L,Téllez-Rojo MM,Mercado-García Adel S,Solano-González M,Hernández-Avila M,Hu H

subject

Has Abstract

pub_date

2003-01-01 00:00:00

pages

S189-95

eissn

0036-3634

issn

1606-7916

journal_volume

45 Suppl 2

pub_type

杂志文章
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    authors: López-Ríos O,Lechuga-Anaya M

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    abstract::The presence of ferruginous bodies (FB) at 90 autopsy cases were analysed. The cases belong to 1975, 1982 and 1988. Two grams of lung was digested and observed the following results: 4.2 FB/g in 1975, 17.0 FB/g in 1982 and 42.5 FB/g in 1988. Males, Mexico City dowlers, smokers and carcinoma bronchogenic group were exp...

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    authors: Arenas Huertero FJ

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    doi:

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    pub_type: 杂志文章,评审

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    authors: Gutiérrez G

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    authors: Hernández-Ronquillo L,Téllez-Zenteno JF,Garduño-Espinosa J,González-Acevez E

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  • [The health problems associated with irrigation with wastewater in Mexico].

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    authors: Cifuentes E,Blumenthal U,Ruiz-Palacios G,Bennett S,Quigley M,Peasey A,Romero-Alvarez H

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    authors: Salinas-Rodríguez A,Manrique-Espinoza B,Acosta-Castillo GI,Franco-Núñez A,Rosas-Carrasco O,Gutiérrez-Robledo LM,Sosa-Ortiz AL

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    abstract::The epidemiologic and demographic transitions have resulted in demographic aging of the Mexican population, increasing the absolute number and percentage of the elderly population. While in 1990, 3.1 million of persons were 65 and older constituting 3.7% of the country's population, these figures are projected to be 1...

    journal_title:Salud publica de Mexico

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    authors: Ham-Chande R

    更新日期:1996-11-01 00:00:00

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