Abstract:
:The development of functional magnetic resonance imaging (fMRI) has brought together a broad community of scientists interested in measuring the neural basis of the human mind. Because fMRI signals are an indirect measure of neural activity, interpreting these signals to make deductions about the nervous system requires some understanding of the signaling mechanisms. We describe our current understanding of the causal relationships between neural activity and the blood-oxygen-level-dependent (BOLD) signal, and we review how these analyses have challenged some basic assumptions that have guided neuroscience. We conclude with a discussion of how to use the BOLD signal to make inferences about the neural signal.
journal_name
Annu Rev Physioljournal_title
Annual review of physiologyauthors
Logothetis NK,Wandell BAdoi
10.1146/annurev.physiol.66.082602.092845subject
Has Abstractpub_date
2004-01-01 00:00:00pages
735-69eissn
0066-4278issn
1545-1585journal_volume
66pub_type
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