Left ventricular mechanics during right ventricular apical or left ventricular-based pacing in patients with chronic atrial fibrillation after atrioventricular junction ablation.

Abstract:

OBJECTIVES:The aim of the study was to evaluate whether left ventricular (LV) mechanics are better under LV-based pacing than under right ventricular (RV) apical pacing in patients with permanent atrial fibrillation (AF) after atrioventricular junction (AVJ) ablation. BACKGROUND:"Ablate and pace" is an acceptable therapy for drug-refractory AF. However, the RV apical stimulation commonly used seems to interfere with the beneficial hemodynamic effect of regularization of heart rhythm. METHODS:The study included 12 patients (5 men, mean age 62 +/- 8.3 years), 6 with impaired and 6 with normal LV systolic function. All of them had a biventricular pacemaker system implanted and underwent atrioventricular node ablation for drug-refractory chronic AF. Using a conductance catheter, we analyzed LV pressure-volume loops during routine coronary angiography in order to evaluate short-term changes in LV mechanics during RV apical and LV-based (LV free wall or biventricular) pacing. RESULTS:Compared with RV pacing, LV-based pacing significantly improved the indexes of LV systolic function (i.e., end-systolic pressure and volume, cardiac index, stroke work, preload recruitable stroke work, maximal rate of rise of LV pressure [dP/dt(max)], LV ejection fraction, and end-systolic elastance). The LV diastolic filling indexes, end-diastolic pressure and volume, were better during LV-based pacing, whereas LV diastolic function indexes, -dP/dt(max), passive diastolic chamber stiffness, and time constant of LV isovolumic relaxation showed no clear change. CONCLUSIONS:In the short term, LV-based pacing is superior to RV apical pacing in terms of contractile function and LV filling after AVJ ablation for drug-refractory AF.

journal_name

J Am Coll Cardiol

authors

Simantirakis EN,Vardakis KE,Kochiadakis GE,Manios EG,Igoumenidis NE,Brignole M,Vardas PE

doi

10.1016/j.jacc.2003.10.038

subject

Has Abstract

pub_date

2004-03-17 00:00:00

pages

1013-8

issue

6

eissn

0735-1097

issn

1558-3597

pii

S0735109704000130

journal_volume

43

pub_type

杂志文章
  • Dynamic fluctuations in blood and spleen radioactivity: splenic contraction and relation to clinical radionuclide volume calculations.

    abstract::Alterations in the blood radioactivity affect ventricular volume calculations using count-based radionuclide ventriculography. To study this phenomenon, the effect of time, posture and supine exercise on blood radioactivity, red blood cell count and splenic radioactivity was evaluated. The red blood cell count, and bl...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(84)80178-3

    authors: Sandler MP,Kronenberg MW,Forman MB,Wolfe OH,Clanton JA,Partain CL

    更新日期:1984-05-01 00:00:00

  • Prognostic value of serum cardiac troponin I in ambulatory patients with chronic renal failure undergoing long-term hemodialysis: a two-year outcome analysis.

    abstract:OBJECTIVES:We sought to evaluate the prognostic value of cardiac troponin I (cTnI) in asymptomatic, ambulatory patients with chronic renal failure treated with long-term hemodialysis. BACKGROUND:Smaller, short-term follow-up studies on this subject have given conflicting results. METHODS:A total of 126 ambulatory pat...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(01)01513-3

    authors: Khan IA,Wattanasuwan N,Mehta NJ,Tun A,Singh N,Singh HK,Vasavada BC,Sacchi TJ

    更新日期:2001-10-01 00:00:00

  • Androgens up-regulate atherosclerosis-related genes in macrophages from males but not females: molecular insights into gender differences in atherosclerosis.

    abstract:OBJECTIVES:This study investigated the effects of androgens on gene expression in male- and female-donor macrophages. BACKGROUND:Men have more severe coronary disease than women. Androgen exposure increases foam cell formation in male but not female macrophages, and male macrophages express >4-fold more androgen recep...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jacc.2003.07.002

    authors: Ng MK,Quinn CM,McCrohon JA,Nakhla S,Jessup W,Handelsman DJ,Celermajer DS,Death AK

    更新日期:2003-10-01 00:00:00

  • Expression profiling of cardiac genes in human hypertrophic cardiomyopathy: insight into the pathogenesis of phenotypes.

    abstract:OBJECTIVES:The goal of this study was to identify genes upregulated in the heart in human patients with hypertrophic cardiomyopathy (HCM). BACKGROUND:Hypertrophic cardiomyopathy is a genetic disease caused by mutations in contractile sarcomeric proteins. The molecular basis of diverse clinical and pathologic phenotype...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(01)01509-1

    authors: Lim DS,Roberts R,Marian AJ

    更新日期:2001-10-01 00:00:00

  • The Essential Role of Educator Development: 10 Years of the ACC Emerging Faculty Program.

    abstract::The American College of Cardiology Emerging Faculty program was developed in 2005 to promote a systematic approach to "educate the educators" through training and mentorship. A primary focus of the program is the biennial Teaching Skills Workshop, which has had 130 participants since its inception and is focused on th...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jacc.2016.02.052

    authors: Auseon AJ,O'Gara PT,Klodas E,Holmes DR Jr,Jackson MJ,Green JS,Konstam MA,Nishimura RA

    更新日期:2016-05-10 00:00:00

  • Changing strategies in the management of heart failure.

    abstract::Forty years ago therapy for congestive heart failure was limited largely to the mercurial diuretics and a variety of cardiac glycoside preparations; these were often ineffective, and the common practice of "pushing" digitalis caused serious, sometimes lethal side effects. Today, a more complete understanding of the re...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章,评审

    doi:10.1016/0735-1097(89)90586-x

    authors: Katz AM

    更新日期:1989-03-01 00:00:00

  • Does lowering pulmonary arterial pressure eliminate severe functional tricuspid regurgitation? Insights from pulmonary thromboendarterectomy.

    abstract:OBJECTIVES:Because pulmonary thromboendarterectomy (PTE) can result in an immediate reduction in pulmonary artery (PA) pressure, we sought to evaluate the effect of PTE on severe tricuspid regurgitation (TR) without tricuspid annuloplasty. BACKGROUND:Few data exist regarding the frequency and magnitude of functional T...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jacc.2003.12.058

    authors: Sadeghi HM,Kimura BJ,Raisinghani A,Blanchard DG,Mahmud E,Fedullo PF,Jamieson SW,DeMaria AN

    更新日期:2004-07-07 00:00:00

  • Reflex control of coronary vascular tone by cardiopulmonary receptors in humans.

    abstract::To examine whether cardiopulmonary receptors participate in the reflex control of coronary vascular resistance, systemic and coronary hemodynamics were assessed before and during -10 mm Hg lower body negative pressure in eight normal subjects and eight hypertensive patients with left ventricular hypertrophy. In both s...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(98)90050-x

    authors: Trimarco B,Vigorito C,Cuocolo A,Ricciardelli B,De Luca N,Volpe M,Lembo G,Condorelli M

    更新日期:1988-05-01 00:00:00

  • Baroreflex sensitivity and variants of the renin angiotensin system genes.

    abstract:OBJECTIVES:Because the renin-angiotensin-aldosterone system (RAS) modifies cardiovascular autonomic regulation, we studied the possible associations between baroreflex sensitivity (BRS) and polymorphism in the RAS genes. BACKGROUND:Wide intersubject variability in BRS is not well explained by cardiovascular risk facto...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(99)00506-9

    authors: Ylitalo A,Airaksinen KE,Hautanen A,Kupari M,Carson M,Virolainen J,Savolainen M,Kauma H,Kesäniemi YA,White PC,Huikuri HV

    更新日期:2000-01-01 00:00:00

  • Transcatheter implantation of homologous "off-the-shelf" tissue-engineered heart valves with self-repair capacity: long-term functionality and rapid in vivo remodeling in sheep.

    abstract:OBJECTIVES:This study sought to evaluate long-term in vivo functionality, host cell repopulation, and remodeling of "off-the-shelf" tissue engineered transcatheter homologous heart valves. BACKGROUND:Transcatheter valve implantation has emerged as a valid alternative to conventional surgery, in particular for elderly ...

    journal_title:Journal of the American College of Cardiology

    pub_type: 评论,杂志文章

    doi:10.1016/j.jacc.2013.09.082

    authors: Driessen-Mol A,Emmert MY,Dijkman PE,Frese L,Sanders B,Weber B,Cesarovic N,Sidler M,Leenders J,Jenni R,Grünenfelder J,Falk V,Baaijens FPT,Hoerstrup SP

    更新日期:2014-04-08 00:00:00

  • Attenuation of interatrial conduction using right atrial septal catheter ablation.

    abstract:OBJECTIVES:We sought to characterize a method of attenuating interatrial conduction using radiofrequency ablated lesions applied to the right atrial septum. BACKGROUND:Interatrial conduction occurs in specific zones. Recent data suggest that interatrial conduction can be important in triggering and sustaining atrial f...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(01)01466-8

    authors: Schwartzman D,Warman EN,Devine WA,Mehra R

    更新日期:2001-09-01 00:00:00

  • Economics of elective coronary revascularization. Comparison of costs and charges for conventional angioplasty, directional atherectomy, stenting and bypass surgery.

    abstract:OBJECTIVES:This study was designed to evaluate more closely the true in-hospital costs of elective revascularization by directional coronary atherectomy and intracoronary stenting and to compare these costs with those of the traditional revascularization alternatives (i.e., conventional balloon angioplasty and coronary...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(93)90415-w

    authors: Cohen DJ,Breall JA,Ho KK,Weintraub RM,Kuntz RE,Weinstein MC,Baim DS

    更新日期:1993-10-01 00:00:00

  • Effects of long-term right ventricular apical pacing on left ventricular perfusion, innervation, function and histology.

    abstract:OBJECTIVES:The purpose of this study was to better understand the effects of long-term right ventricular pacing on left ventricular perfusion, innervation, function and histology. BACKGROUND:Long-term right ventricular apical pacing is associated with increased congestive heart failure and mortality compared with atri...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(94)90567-3

    authors: Lee MA,Dae MW,Langberg JJ,Griffin JC,Chin MC,Finkbeiner WE,O'Connell JW,Botvinick E,Scheinman MM,Rosenqvist M

    更新日期:1994-07-01 00:00:00

  • Effectiveness of fludrocortisone and salt in preventing syncope recurrence in children: a double-blind, placebo-controlled, randomized trial.

    abstract:OBJECTIVES:We sought to evaluate the effectiveness of salt and fludrocortisone versus placebo in the prevention of syncope recurrence in children. BACKGROUND:Intravascular volume expansion with fludrocortisone and salt has been reported to be effective in the treatment of syncope in children. However, no pediatric pla...

    journal_title:Journal of the American College of Cardiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/j.jacc.2004.11.033

    authors: Salim MA,Di Sessa TG

    更新日期:2005-02-15 00:00:00

  • Tachycardia, contractility and volume loading alter conventional indexes of coronary flow reserve, but not the instantaneous hyperemic flow versus pressure slope index.

    abstract:OBJECTIVES AND BACKGROUND:Because measurements of flow reserve are often made in the setting of fluctuating hemodynamic variables that cause alterations in basal or hyperemic coronary blood flow, traditional flow reserve indexes may be difficult to interpret. Prior work in this laboratory has suggested that the instant...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(92)90386-2

    authors: Cleary RM,Ayon D,Moore NB,DeBoe SF,Mancini GB

    更新日期:1992-11-01 00:00:00

  • Tuberculous pericarditis: ten year experience with a prospective protocol for diagnosis and treatment.

    abstract::Thirteen patients with tuberculous pericarditis (12 men and 1 woman aged 13 to 70 years [mean 41]) were identified in a group of 294 patients consecutively admitted for primary acute pericardial disease. The diagnosis was made by the following studies: sputum culture (n = 4), culture of pericardial fluid obtained by p...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(88)90203-3

    authors: Sagristà-Sauleda J,Permanyer-Miralda G,Soler-Soler J

    更新日期:1988-04-01 00:00:00

  • Electroanatomic mapping of arrhythmogenic right ventricular dysplasia.

    abstract:OBJECTIVES:We tested the hypothesis that spatial association of low-amplitude intracardiac electrograms can identify the presence, location and extent of dysplastic regions in arrhythmogenic right ventricular dysplasia (ARVD). BACKGROUND:Arrhythmogenic right ventricular dysplasia is a right ventricular (RV) cardiomyop...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(01)01625-4

    authors: Boulos M,Lashevsky I,Reisner S,Gepstein L

    更新日期:2001-12-01 00:00:00

  • Effect of managed care on cardiovascular specialists: involvement, attitudes and practice adaptations.

    abstract:OBJECTIVES:This study was undertaken to determine the extent to which cardiovascular specialists are involved with and affected by managed care and to ascertain their attitudes toward it. This survey also served as the follow-up to an initial study on the subject performed by the American College of Cardiology in 1993....

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/S0735-1097(96)00455-X

    authors: DeMaria AN,Lee TH,Leon DF,Ullyot DJ,Wolk MJ,Mills PS,Fay SC,Brown JH,Flatau CN,Bodycombe DP

    更新日期:1996-12-01 00:00:00

  • Assessment of cardiovascular function by digital angiocardiography.

    abstract::A methodology for computerized digital videoangiocardiography is briefly described. Single or biplane projection image series from the cardiovascular system are combined with the corresponding physiologic (electrocardiogram, blood pressure, etc.) reference data, digitized and stored as a block of simultaneously availa...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(85)80156-x

    authors: Heintzen PH,Bürsch HJ,Hahne HJ,Brennecke R,Budach W,Lange P

    更新日期:1985-01-01 00:00:00

  • Embolic potential of left ventricular thrombus after myocardial infarction: a two-dimensional echocardiographic study of 119 patients.

    abstract::Left ventricular thrombus complicating myocardial infarction was diagnosed by two-dimensional echocardiography in 119 patients. The infarct site was anterior in 98 patients and inferior in 11. Systemic embolism occurred in 26 patients (stroke in 18, lower limb embolism in 7 and mesenteric embolism in 1). A protruding ...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(85)80336-3

    authors: Visser CA,Kan G,Meltzer RS,Dunning AJ,Roelandt J

    更新日期:1985-06-01 00:00:00

  • Syncope in hypertrophic cardiomyopathy: multivariate analysis of prognostic determinants.

    abstract::Twenty-nine consecutive patients with symptomatic hypertrophic cardiomyopathy and a mean age of 44.8 +/- 12.2 years (range 21 to 63) underwent complex invasive and noninvasive testing to identify a risk profile for syncope. Clinical, morphologic, electrophysiologic and hemodynamic variables at rest and at a symptom-li...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(90)90222-b

    authors: Nienaber CA,Hiller S,Spielmann RP,Geiger M,Kuck KH

    更新日期:1990-04-01 00:00:00

  • Inotropic effect of nicardipine in patients with heart failure: assessment by left ventricular end-systolic pressure-volume analysis.

    abstract::Nicardipine, a new dihydropyridine calcium channel blocker, has been investigated for the treatment of coronary artery disease and heart failure. To assess the inotropic effect of nicardipine in humans independent of its vasodilator effect, equihypotensive doses of intravenous nitroprusside (mean infusion rate 65 +/- ...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(89)90437-3

    authors: Aroney CN,Semigran MJ,Dec GW,Boucher CA,Fifer MA

    更新日期:1989-11-01 00:00:00

  • Rationale and design of the International Verapamil SR/Trandolapril Study (INVEST): an Internet-based randomized trial in coronary artery disease patients with hypertension.

    abstract:OBJECTIVES:The primary objective of the International Verapamil SR/Trandolapril Study (INVEST) is to compare the risk for adverse outcomes (all-cause mortality, nonfatal myocardial infarction [MI] or nonfatal stroke) in hypertensive patients with coronary artery disease (CAD) treated with either a calcium antagonist-ba...

    journal_title:Journal of the American College of Cardiology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0735-1097(98)00423-9

    authors: Pepine CJ,Handberg-Thurmond E,Marks RG,Conlon M,Cooper-DeHoff R,Volkers P,Zellig P

    更新日期:1998-11-01 00:00:00

  • Wolff-Parkinson-White syndrome and supraventricular tachycardia during infancy: management and follow-up.

    abstract::The records of 90 patients with Wolff-Parkinson-White syndrome who presented with supraventricular tachycardia in the first 4 months of life were reviewed. Among these, 63% were male. Structural heart disease was present in 20%, most commonly Ebstein's anomaly. All patients presented with a regular narrow QRS tachycar...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(85)80095-4

    authors: Deal BJ,Keane JF,Gillette PC,Garson A Jr

    更新日期:1985-01-01 00:00:00

  • Sodium Glucose Cotransporter-2 Inhibition and Cardiorenal Protection: JACC Review Topic of the Week.

    abstract::Poorly controlled type 2 diabetes mellitus is associated with the development of cardiovascular and renal complications, resulting in significant morbidity and mortality. Intensive glycemic control has been a major focus for clinical trials and novel drug development. However, narrow treatment strategies developed str...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jacc.2019.09.022

    authors: Cherney DZ,Odutayo A,Aronson R,Ezekowitz J,Parker JD

    更新日期:2019-11-19 00:00:00

  • Intracoronary ultrasound assessment of directional coronary atherectomy: immediate and follow-up findings.

    abstract:OBJECTIVES:This study was conducted to assess the relations among intracoronary ultrasound, angiographic and histologic data obtained from patients with coronary artery disease successfully treated by directional coronary atherectomy. In addition, it was designed to elucidate whether some aspects of intravascular ultra...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(93)90667-p

    authors: Suárez de Lezo J,Romero M,Medina A,Pan M,Pavlovic D,Vaamonde R,Hernández E,Melián F,López Rubio F,Marrero J

    更新日期:1993-02-01 00:00:00

  • Antimyosin scintigraphy and immunohistologic analysis of endomyocardial biopsy in patients with clinically suspected myocarditis--evidence of myocardial cell damage and inflammation in the absence of histologic signs of myocarditis.

    abstract:OBJECTIVES:This study compares the results of antimyosin scintigraphy in patients with clinically suspected myocarditis with histologic and immunohistologic findings in the endomyocardial biopsy. BACKGROUND:In patients with clinically suspected myocarditis, antimyosin scintigraphy often demonstrates myocardial cell da...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/s0735-1097(98)00397-0

    authors: Kühl U,Lauer B,Souvatzoglu M,Vosberg H,Schultheiss HP

    更新日期:1998-11-01 00:00:00

  • Enhanced shear-induced platelet aggregation in patients who experience subacute stent thrombosis: a case-control study.

    abstract:OBJECTIVES:The goal of this study was to identify differences in shear-induced platelet aggregation (SIPA) between patients who did or did not experience subacute stent thrombosis (SAT). BACKGROUND:Despite dual antiplatelet therapy, SAT after coronary stenting occurs in approximately 1% of patients. There is no accept...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jacc.2004.10.079

    authors: Ajzenberg N,Aubry P,Huisse MG,Cachier A,El Amara W,Feldman LJ,Himbert D,Baruch D,Guillin MC,Steg PG

    更新日期:2005-06-07 00:00:00

  • Heart rate adjustment of ST segment depression and performance of the exercise electrocardiogram: a critical evaluation.

    abstract::Analysis of the rate-related change in exercise-induced ST segment depression using the exercise ST segment/heart rate slope and ST segment/heart rate index can improve the accuracy of the exercise electrocardiogram (ECG) for the identification of patients with coronary artery disease, recognition of patients with ana...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章,评审

    doi:10.1016/0735-1097(95)00085-i

    authors: Okin PM,Kligfield P

    更新日期:1995-06-01 00:00:00

  • The role of percutaneous aortic balloon valvuloplasty in patients with cardiogenic shock and critical aortic stenosis.

    abstract:OBJECTIVES:The goal of this study was to evaluate the role of percutaneous aortic valvuloplasty in patients with cardiogenic shock due to severe aortic stenosis and associated major comorbid conditions and to establish predictors of survival. BACKGROUND:The prognosis for patients in cardiogenic shock with severe aorti...

    journal_title:Journal of the American College of Cardiology

    pub_type: 杂志文章

    doi:10.1016/0735-1097(94)90592-4

    authors: Moreno PR,Jang IK,Newell JB,Block PC,Palacios IF

    更新日期:1994-04-01 00:00:00