Bcl-2 prevents loss of cell viability and caspase activation induced by 3-nitropropionic acid in GT1-7 cells.

abstract：:The endometrial effects of vaginal progesterone have been found to be unexpectedly reliable. This has led us to suspect that a local direct vagina-to-uterus transport or first uterine pass effect was the basis of the uterine targeting of vaginal progesterone. After vaginal administration of progesterone, uterine tissu...

journal_title：Annals of the New York Academy of Sciences

authors： De Ziegler D,Bulletti C,De Monstier B,Jääskeläinen AS

更新日期：1997-09-26 00:00:00

abstract：:The human endometrium is an extremely sensitive target for steroid hormones. During the menstrual cycle, this tissue undergoes dynamic changes that are reflected on the surface morphology of the epithelium and that can be followed by scanning electron microscopy. The morphologic changes peak at the midsecretory phase,...

journal_title：Annals of the New York Academy of Sciences

authors： Nikas G,Makrigiannakis A,Hovatta O,Jones HW Jr

更新日期：2000-01-01 00:00:00

abstract：:Reducing emissions from deforestation and forest degradation (REDD+) provides financial compensation to land owners who avoid converting standing forests to other land uses. In this paper, we review the main opportunities and challenges for REDD+ implementation, including expectations for REDD+ to deliver on multiple ...

journal_title：Annals of the New York Academy of Sciences

authors： Venter O,Koh LP

更新日期：2012-02-01 00:00:00

abstract：:Reports on patients with hemiparalysis indicate the importance of the nervous system for the pathophysiology of rheumatoid arthritis (RA) or osteoarthritis (OA). Norepinephrine (NE) and opioids seem to be more antiinflammatory neurotransmitters whereas substance P is proinflammatory. The study aimed to investigate the...

journal_title：Annals of the New York Academy of Sciences

authors： Miller LE,Wessinghage D,Müller-Ladner U,Schölmerich J,Falk W,Kerner T,Straub RH

更新日期：1999-06-22 00:00:00

abstract：:The molecular genetic basis of adaptive change in phenotype is a major outstanding issue in evolutionary biology. Evolutionary change in coat and plumage color is a promising system for making progress in this field. Most notably, recent work on the molecular genetic basis of hair and feather color has identified seve...

journal_title：Annals of the New York Academy of Sciences

authors： Mundy NI,Kelly J,Theron E,Hawkins K

更新日期：2003-06-01 00:00:00

abstract：:The muscular dystrophies, which cause progressive weakening of the skeletal muscles, are frequently associated with cardiomyopathy. In fact, the leading cause of mortality in patients with Duchenne muscular dystrophy, the most common and most severe type of muscular dystrophy, is heart failure due to cardiomyopathy. T...

journal_title：Annals of the New York Academy of Sciences

authors： Kuno A,Tanno M,Horio Y

更新日期：2015-08-01 00:00:00

abstract：:The endothelial cells cultured in collagen gel caused upregulation of KDR expression, which resulted in an increase in tube formation. Endothelial cells exposed to high glucose (33 mmol/l) for 30 days increased the tube formation induced by VEGF, but not by serum and bFGF. Immunohistochemical study showed that KDR exp...

journal_title：Annals of the New York Academy of Sciences

authors： Murota SI,Onodera M,Morita I

更新日期：2000-05-01 00:00:00

abstract：:Activation of cyclic nucleotide-gated (CNG) channels represents the final step in the transduction pathways in both vision and olfaction. Over the past several years, CNG channels have been found in a variety of other cell types where they might fulfill various physiological functions. The olfactory and photoreceptor ...

journal_title：Annals of the New York Academy of Sciences

authors： Broillet MC,Firestein S

更新日期：1999-04-30 00:00:00

abstract：:Auditory stimulation via rhythmic cues can be used successfully in the rehabilitation of motor function in patients with motor disorders. A prototypical example is provided by dysfunctional gait in patients with idiopathic Parkinson's disease (PD). Coupling steps to external rhythmic cues (the beat of music or the sou...

journal_title：Annals of the New York Academy of Sciences

authors： Bella SD,Benoit CE,Farrugia N,Schwartze M,Kotz SA

更新日期：2015-03-01 00:00:00

abstract：:Purified human urinary CSF-1 was used for production of polyclonal CSF antibodies in rabbits. The purified CSF was iodinated by a modified chloramine-T technique with retention of biologic activity. Dilutions of anti-CSF were reacted with 15,000 cpm of 125I-CSF in EDTA-phosphate buffer for 48 hr. Sheep antirabbit seru...

journal_title：Annals of the New York Academy of Sciences

authors： Shadduck RK,Waheed A

更新日期：1989-01-01 00:00:00

abstract：:BALB/c mice infected with Rowson-Parr virus, a lymphatic leukemia virus isolated from the Friend complex, undergo a rapid depression of antibody response. Spleen cells from these mice in culture show a similar deficit in the response to stimulation with sheep red cells and inhibit the reactivity of normal splenocytes....

journal_title：Annals of the New York Academy of Sciences

authors： Bendinelli M,Toniolo A

更新日期：1976-01-01 00:00:00

abstract：:Immunoglobulin 4 (IgG4) is one of four human IgG subclasses and has several unique functional characteristics. It exhibits low affinity for complement and for most Fc receptors. It furthermore has generally high affinity for its antigen, with binding occurring in a monovalent fashion, as IgG4 can exchange Fab-arms wit...

journal_title：Annals of the New York Academy of Sciences

authors： Huijbers MG,Plomp JJ,van der Maarel SM,Verschuuren JJ

更新日期：2018-02-01 00:00:00

abstract：:It is well known that hemodynamic load is one of the most important determinants of cardiac structure and function. Circadian variations in blood pressure (BP) values are usually accompanied by consensual changes in peripheral resistance and/or cardiac output. In recent years, in hypertensive patients with left ventri...

journal_title：Annals of the New York Academy of Sciences

authors： Rizzoni D,Agabiti-Rosei E

更新日期：1996-08-15 00:00:00

abstract：:Signal hyperintensities on magnetic resonance imaging (MRI) are increased in the white matter (WMH) and deep gray matter in dementia and depression and may have similar pathologies. However, no previous study has examined WMH in subjects with major depression. We carried out in vitro MRI on brain tissue from elderly s...

journal_title：Annals of the New York Academy of Sciences

authors： Thomas AJ,Perry R,Barber R,Kalaria RN,O'Brien JT

更新日期：2002-11-01 00:00:00

abstract：:Leukocyte trafficking from the blood stream to tissues is essential for continuous surveillance of foreign antigens. This dynamic process, designated as the leukocyte adhesion cascade, involves distinct steps. In leukocyte adhesion deficiency (LAD) I the firm adhesion of leukocyte to the endothelium is defective, due ...

journal_title：Annals of the New York Academy of Sciences

authors： Hanna S,Etzioni A

更新日期：2012-02-01 00:00:00

abstract：:In order to analyze neuronal computations in the first olfactory processing center, the olfactory bulb, we measured odor-evoked activity patterns across large numbers of neurons within the intact olfactory bulb of zebrafish using optical and electrophysiological methods. We found that the olfactory bulb performs multi...

journal_title：Annals of the New York Academy of Sciences

authors： Friedrich RW,Yaksi E,Judkewitz B,Wiechert MT

更新日期：2009-07-01 00:00:00

abstract：:Gene therapy as an immunomodulatory approach has the potential to treat various inherited and acquired immune-based human diseases. However, its clinical application has several challenges, varying from the efficiency of gene transfer, control of gene expression, cell and tissue targeting, and safety concerns associat...

journal_title：Annals of the New York Academy of Sciences

authors： Singh NP,Yolcu ES,Askenasy N,Shirwan H

更新日期：2005-11-01 00:00:00

abstract：:Intracerebral administration of the excitotoxin ibotenate to new-born mice induced white-matter lesions mimicking the periventricular leukomalacia occurring in human premature babies. In this model, co-injection of vasoactive intestinal peptide (VIP) prevented white-matter lesions. VIP did not prevent the initial appe...

journal_title：Annals of the New York Academy of Sciences

authors： Gressens P

更新日期：1999-01-01 00:00:00

abstract：:Although the evidence for oxidative stress for air pollution in the human lung is fragmentary, the hypothesis that oxidative stress is an important, if not the sole, mechanism of toxicity of oxidizing air pollutants and tobacco smoke is compelling and growing. First, biochemical mechanisms have been worked out for oxi...

journal_title：Annals of the New York Academy of Sciences

authors： Menzel DB

更新日期：1992-09-30 00:00:00

abstract：:Cotyledons of dark-grown watermelon seedlings contain during the first period of germination, 4 and later 5 MDH isoenzymes. Whereas isoenzymes I, II, and IV belong to the cytosol, isoenzyme III is confined to the mitochondria (mMDH) and isoenzyme V to the glyoxysomes (gMDH). The organelle-bound MDHs were purified to h...

journal_title：Annals of the New York Academy of Sciences

authors： Hock B,Gietl C

更新日期：1982-01-01 00:00:00

abstract：:Our paper reviews recent progress in the study and understanding of observed trends in extreme rainfall events in the Metropolitan Area of São Paulo (MASP). These are discussed in relation to hydrometeorological hazards that trigger natural disasters, such as flash floods, landslides, and droughts, that affect the pop...

journal_title：Annals of the New York Academy of Sciences

authors： Marengo JA,Alves LM,Ambrizzi T,Young A,Barreto NJC,Ramos AM

更新日期：2020-07-01 00:00:00

abstract：:Inflammation plays a key role in excessive bone loss in conditions such as rheumatoid arthritis and periodontitis. An important paradigm in immunology is that inflammatory factors activate feedback inhibition mechanisms to restrain inflammation and limit associated tissue damage. We hypothesized that inflammatory fact...

journal_title：Annals of the New York Academy of Sciences

authors： Ivashkiv LB,Zhao B,Park-Min KH,Takami M

更新日期：2011-11-01 00:00:00

abstract：:Caloric restriction (CR) is well described and has received extensive attention for its multiple benefits, including longevity and stress resistance. However, some studies have shown that CR negatively influences bone, although a mechanism hasn't been provided. Adiponectin, an adipocyte-derived hormone, can affect bon...

journal_title：Annals of the New York Academy of Sciences

authors： Zhu J,Liu C,Jia J,Zhang C,Yuan W,Leng H,Xu Y,Song C

更新日期：2020-08-01 00:00:00

abstract：:Alzheimer's disease (AD) is a heterogeneous and progressive neurodegenerative disease which in Western societies mainly accounts for clinical dementia. A high proportion of women are affected by this disease, especially at a very advanced age, which might to a large extent be associated with the fact that women live l...

journal_title：Annals of the New York Academy of Sciences

authors： Candore G,Balistreri CR,Grimaldi MP,Vasto S,Listì F,Chiappelli M,Licastro F,Lio D,Caruso C

更新日期：2006-11-01 00:00:00

abstract：:A diagnostic test is particularly beneficial if it reveals the level of susceptibility prior to onset of a disease process. In the case of childhood caries, such a diagnostic test affords the opportunity for preventive measures to be implemented before caries begins. Salivary glycoproteins contain a wealth of individu...

journal_title：Annals of the New York Academy of Sciences

authors： Denny PC,Denny PA,Takashima J,Galligan J,Navazesh M

更新日期：2007-03-01 00:00:00

abstract：:This chapter examines trends in private and public health coverage, as well as implications for vulnerable populations and health disparities. We find that there has been erosion in employment-based health benefits. Both the percentage of employers offering coverage and the percentage of workers with coverage declined...

journal_title：Annals of the New York Academy of Sciences

authors： Shields AE,McGinn-Shapiro M,Fronstin P

更新日期：2008-01-01 00:00:00

abstract：:Bioelectrical impedance analysis (BIA) has been proposed for measuring fat-free mass, total body water, percent fat, body cell mass, intracellular water, and extracellular water: a veritable laboratory in a box. Although it is unlikely that BIA is quite this versatile, correlations have been demonstrated between BIA a...

journal_title：Annals of the New York Academy of Sciences

authors： Schoeller DA

更新日期：2000-05-01 00:00:00

abstract：:Population trends indicate that in the near future the size of the elderly population will increase. This will result in a large increment in the numbers of persons suffering mild to severe levels of cognitive impairment. While considerable efforts continue to be made to explain brain changes associated with Alzheimer...

journal_title：Annals of the New York Academy of Sciences

authors： de Leon MJ,Convit A,George AE,Golomb J,de Santi S,Tarshish C,Rusinek H,Bobinski M,Ince C,Miller D,Wisniewski H

更新日期：1996-01-17 00:00:00

abstract：:In this review, we present (1) the scientific basis for the use of high-dose immunosuppression followed by autologous peripheral blood hematopoietic stem cell transplantation for newly diagnosed type 1 diabetes (T1D); (2) an update of the clinical and laboratory outcome of 20 patients transplanted at the University Ho...

journal_title：Annals of the New York Academy of Sciences

authors： Voltarelli JC,Couri CE,Stracieri AB,Oliveira MC,Moraes DA,Pieroni F,Barros GM,Madeira MI,Malmegrim KC,Foss-Freitas MC,Simões BP,Foss MC,Squiers E,Burt RK

更新日期：2008-12-01 00:00:00

abstract：:The aim of this study was to clarify the role of nitric oxide (NO) and lipid peroxidation (LPO) processes as well as the contribution of various neurotransmitters in pathophysiological mechanisms of neurotoxicity induced by amphetamine (AMPH). NO level was determined directly in brain tissues using electron paramagnet...

journal_title：Annals of the New York Academy of Sciences

authors： Bashkatova V,Kraus MM,Vanin A,Hornick A,Prast H

更新日期：2004-10-01 00:00:00