Abstract:
:This review summarizes the knowledge and highlights recent advances in clinical research of retinopathy of prematurity (ROP). This disease is still important, because improvements in neonatal intensive care during the last years have increased the survival of the most immature newborns, but did not diminish the ROP frequency. Ophthalmologic screening and, if applicable, laser treatment at the optimal time for advanced ROP prevents blindness in most cases. The history, classification and the modern concepts of ROP pathophysiology are described. The results of various multicenter treatment trials are summarized. The current German screening guidelines are discussed with the guidelines of other nations. The therapeutic treatment strategies and the treatment results are discussed. The ophthalmologic disorders of former preterm infants, as higher rates of amblyopia, strabismus, and refractive error, are mentioned. Possible future therapies, e. g. anti-angiogenic factors are discussed.
journal_name
Klin Monbl Augenheilkdjournal_title
Klinische Monatsblatter fur Augenheilkundeauthors
Jandeck C,Kellner U,Foerster MHdoi
10.1055/s-2004-812886subject
Has Abstractpub_date
2004-03-01 00:00:00pages
147-59issue
3eissn
0023-2165issn
1439-3999journal_volume
221pub_type
杂志文章,评审abstract:BACKGROUND:Long-term follow-up and angiographic findings of serpiginous choroiditis, a chronic disease with recurrences of unknown origin, are reported. PATIENTS AND METHODS:A retrospective analysis of the data of 4 patients with serpiginous choroidopathy, who were treated in the eye clinic of Mainz in the past 10-18 ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2006-926575
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:Gene therapy has gained increasing attention and a number of ongoing clinical trials have been initiated. This article provides current perspectives and limitations on gene therapy in ophthalmology. Since a number of comprehensive studies on gene therapy for retinal diseases already exist, we focus attention...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-2001-13073
更新日期:2001-03-01 00:00:00
abstract:BACKGROUND:By allowing one to detect fluorescence beyond the retinal pigment epithelium, indocyanine green angiography (ICGA) has made it possible to analyse the choroidal vessels. Our aim was to characterize choroidal vasculitis in posterior uveitis using ICGA. METHODS:Charts of active posterior uveitis patients with...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2002-30661
更新日期:2002-04-01 00:00:00
abstract:BACKGROUND:The aim of this study was to assess the significance of different clinical appearances of the vitreoretinal interface in the surgical management of acute postoperative endophthalmitis. PATIENTS AND METHODS:22 patients underwent vitrectomy and were divided intraoperatively in 3 groups according to the degree...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0028-1109286
更新日期:2009-04-01 00:00:00
abstract::As a result of an acute pathologic event ophthalmic arterial pressure may fall below a level necessary to supply sufficient blood to the eye and optic nerve, and thus to preserve full visual function. A sudden partial or even total loss of visual function. A sudden partial or even total loss of vision may follow. In s...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1057432
更新日期:1980-02-01 00:00:00
abstract:BACKGROUND:Computer-controlled video keratoscopy is being employed ever more frequently and for various indications. PATIENTS:We have studied the effects of high-viscosity and low-viscosity tear substitutes on the corneal topography, one and five minutes after application to 14 normal eyes of 7 subjects, and compared ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1035260
更新日期:1996-06-01 00:00:00
abstract::The response by 14 patients with open-angle glaucoma to treatment with carteolol 1% eye drops was investigated during a study lasting up to 15 months. Statistical analysis of the data revealed that carteolol had a highly significant IOP-lowering effect in all the patients studied. The mean decrease in IOP was as much ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 临床试验,杂志文章
doi:10.1055/s-2008-1050860
更新日期:1986-12-01 00:00:00
abstract:BACKGROUND:In the diagnosis of retinal and cerebral vascular occlusion and migraine amaurosis fugax may be an important symptom. To evaluate the relation between cardiovascular diseases and amaurosis fugax we investigated the risk factors in patients with amaurosis fugax. MATERIALS AND METHODS:Twenty-four patients (14...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1035187
更新日期:1996-03-01 00:00:00
abstract:INTRODUCTION:Chronic hepatitis C-therapy is limited to the combined use of PEG-ylated interferons and ribavirin. Side effects of this therapy include retinal changes that manifest with bleeding, cotton wool spots and/or thrombosis. PATIENT:A 51-year-old man presented with a sudden decrease of visual acuity. Chronic he...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2004-813607
更新日期:2004-09-01 00:00:00
abstract::The action of some drugs on the eye may lead to the occurrence of unforeseen ocular and extraocular reactions. Vincaleukoblastin (Velbe) provokes serious corneal lesions with a healing time of two weeks and a half. The local application of Neo-Synephrine eye drops (10%) and Mydrial-Atropine ointment may lead in the ca...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1976-07-01 00:00:00
abstract:BACKGROUND:Vitamin A, the fat soluble vitamin, must be supplied orally before resorption in the mucosa of the small intestine and storage in the liver. Vitamin A deficiency can cause alterations in the anterior segment of the eye, from Bitot spots, which are reversible, to irreversible keratomalacia. PATIENTS AND METH...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1045496
更新日期:1994-08-01 00:00:00
abstract::Immune reactions against corneal transplants cause most of the graft failures during the first 24 months after keratoplasty. This is partly due to inadequate diagnosis and therapy. After a short discussion of the experimental and clinical background, different kinds of characteristic immune reactions are demonstrated ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1977-11-01 00:00:00
abstract::Two tissue specimens obtained by trabeculectomy from infant eyes with different reactive changes in their chamber angles due to previous trabeculotomies are described and discussed. Both eyes had been operated on glaucoma for several times. In the first case, the trabeculotomy had resulted in the formation of laminar ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1057503
更新日期:1980-04-01 00:00:00
abstract::Using mobile OCT equipment and remote ophthalmological diagnosis of n = 1538 diabetics in 17 diabetes practices in Germany, we found diabetic macular edema in 10.1% of the patients and retinal bleedings or microaneurysms in 15.6%. In 1.62% of the diabetics examined, the size of the edema was > 0.4 mm², in 7% the retin...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/a-1194-5211
更新日期:2020-11-01 00:00:00
abstract::Purpose OCT-A is a new method to visualise the 2D and 3D structures of neovascular complexes in exudative AMD. The aim of the present study was to characterise type 2 CNV in different 2D segmentations and in 3D imaging and to investigate changes during anti-VEGF treatment. Methods 12 patients with type 2 CNV in FA and...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0043-118346
更新日期:2017-09-01 00:00:00
abstract::In a randomized and controlled study (already published) the efficacy and safety of Pindolol eye drops 1% were compared with Timolol eye drops 0.5% in the treatment of open-angle glaucoma over a period of 6 months. With the exception of some allergic reactions there was no difference between the two with regard to IOP...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050872
更新日期:1985-01-01 00:00:00
abstract::Die Tränendrüse kann von einer Vielzahl neoplastischer, infektiöser und autoimmunologischer Erkrankungen betroffen sein. Eine radiologische Charakterisierung der Veränderungen kann Hinweise für die differenzialdiagnostische Einordnung liefern. Erkrankungen der ableitenden Tränenwege, insbesondere Tränenwegsverschlüsse...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0033-1358102
更新日期:2015-03-01 00:00:00
abstract::The indications for anterior vitrectomy are presented and the surgical technique is described. An analysis is made of the results of anterior vitrectomy in 93 eyes followed for 4 years and compared with the results of a previous study in which vitreous loss was treated more conservatively. The results of anterior vitr...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1977-06-01 00:00:00
abstract:BACKGROUND:The aim of this study was to compare the results of intraocular pressure (IOP) measurements obtained using the pressure phosphene tonometer Proview with those from Goldmann applanation tonometer (GAT) in normal and glaucomatous eyes. PATIENTS AND METHODS:The IOP in 150 eyes of 62 healthy volunteers and 88 p...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2006-927094
更新日期:2006-11-01 00:00:00
abstract:PURPOSE:The purpose of this study was to determine the surgical outcome, dose-effect (DE), and degree of binocularity in patients undergoing surgery for consecutive exotropia following initial surgery of esotropia. PATIENTS/METHODS:Twenty-one patients were identified. We analyzed the mean angle of deviation pre- and p...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/a-1097-5653
更新日期:2020-04-01 00:00:00
abstract::The problems of optical correction of unilateral traumatic aphakia are discussed. The treatment of choice is a combined Cataract-operation with intraocular lens implants. The operation must be done as soon as the eye is free of inflammation. Prescription of bifocal glasses in addition to pseudophakoi is necessary. Wit...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 临床试验,杂志文章
doi:
更新日期:1978-04-01 00:00:00
abstract:BACKGROUND:We present the description of a successful outcome of intravitreal triamcinolone injection (IVTA) in a patient with cystoid macular oedema (CME) and severe retinal vasculitis suggestive of ocular Behçet's disease. HISTORY AND SIGNS:A healthy 32 year-old Caucasian man presented initially with right retinal v...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1027351
更新日期:2008-05-01 00:00:00
abstract:BACKGROUND:Subretinal perfluorocarbon liquid (PFCL) droplets are occassionally seen after vitreoretinal surgery for retinal detachment. Usually they are located peripherally without causing complications and therapeutic consequences. In contrast, centrally located PFCL droplets affect final visual outcomes. In animal e...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0031-1299159
更新日期:2012-07-01 00:00:00
abstract::The value of a register of corneal grafts is that it can provide new data about the long-term outcome of corneal transplantation and may allow a more reasoned distribution of scarce donor corneas. The large numbers of cases and events can accommodate wide variations in practice patterns without losing statistical powe...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1045527
更新日期:1994-11-01 00:00:00
abstract:BACKGROUND:The correction of lower eyelid retraction remains a challenge with established techniques having disadvantages. A recently described alternative is implantation of an ultrathin high density porous polyethylene lower eyelid spacer (Medpor LES). We report our experience on implanting this Medpor LES, especiall...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 临床试验,杂志文章
doi:10.1055/s-2006-926508
更新日期:2006-07-01 00:00:00
abstract::Between August 1982 and August 1984 3059 intraocular operations were performed with topical prophylactic antibiotics. Results of conjunctival cultures did not influence the surgical schedule. 8179 intraocular operations were performed between September 1984 and August 1988. An intraocular operation was postponed until...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1045734
更新日期:1992-03-01 00:00:00
abstract::Increased blood sugar levels may influence the refractive power of the lens in juvenile diabetics, and can lead to the rare true diabetic cataract ("snow-storm cataract"). Surplus glucose induces accumulation of the sugar alcohol within the cells, thus generating disturbances of the osmotic balance and finally causing...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050822
更新日期:1986-11-01 00:00:00
abstract::360 patients with unilateral exophthalmos were examined with echoophthalmograph to study the diagnostical possibilities of a method of echography in orbital tumors. The findings of para- and transbulbal methodics were checked in 140 patients. The tonometry of tumors and soft orbital tissues was performed. The methodic...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1975-02-01 00:00:00
abstract::Ovid's "De medicamine faciei feminae" contains the astonishing sentence "Culta placent - all that is artificial is beautiful". In his "Éloge du maquillage" Baudelaire, buidling on Ovid's argument, states that first culture as picture and construction of beauty brings forth the truth of Nature and claims that cosmetics...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0032-1328108
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Measles retinitis is rare in immunocompetent patients and has recently been only sporadically described. This case report reveals the clinical picture, the course of the disease and the prognosis of this entity. HISTORY AND FINDINGS:One month after a diagnosed measles infection, a 12-year-old girl presented...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1045509
更新日期:1994-09-01 00:00:00