Abstract：
:In whole animals, ozone acutely impairs pulmonary function, an effect which may be mediated by eicosanoids. This study determined if the lung itself, separated from blood components and the CNS, responds to ozone with increased eicosanoid production and decreased function. Wistar rat lungs were placed in a negatively ventilated, buffer-perfused, isolated system, where they were exposed to filtered air or 1 ppm ozone for 3 hr. Ozone increased lung resistance (P = 0.02) and decreased dynamic compliance (P = 0.003, multivariate ANOVA for repeated measures). Pulmonary artery pressure, lung weight/body weight, and cells in lung lavage (BALF) did not change. In the perfusate, ozone increased the concentration of 6-keto-PGF1 alpha, PGF2 alpha, PGD2, and TxB2 (all P < 0.05, t test) but not LTC4/D4 or PGE2. In BALF, ozone did not change the concentrations of any of the arachidonic acid metabolites tested (PGE2, 6-keto-PGF1 alpha, PGD2, or LTC4/D4). We conclude that ozone increased intravascular concentrations of some cyclooxygenase products in the isolated buffer-perfused lung, an effect associated with reduced lung function.
journal_name
Environ Resjournal_title
Environmental researchauthors
Joad JP,McDonald RJ,Giri SN,Bric JMdoi
10.1006/enrs.1994.1054subject
Has Abstractpub_date
1994-08-01 00:00:00pages
186-97issue
2eissn
0013-9351issn
1096-0953pii
S0013-9351(84)71054-1journal_volume
66pub_type
杂志文章abstract：:The adsorption dynamics of common solid sorbents against various pollutant species are yet poorly understood with respect to the retrograde phenomenon in which the relationship between breakthrough vs. pulled volume is characterized by an early unusual trend (initial increase followed by a decrease to a minimum) and b...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2019.108737
更新日期：2019-11-01 00:00:00
abstract：:Compliance with 24-h urine samples can be low in population-based studies and first morning void urine samples are often collected for convenience. Interpretation of arsenic concentrations in urine is influenced by a range of factors unrelated to exposure. To reduce the influence of such factors, creatinine adjustment...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1006/enrs.2002.4339
更新日期：2002-03-01 00:00:00
abstract：:Atopic dermatitis is one of the most common inflammatory skin diseases among children and adults. Although the risk factors for atopic dermatitis have not yet been fully identified, exposure to mercury may be an important environmental risk factor. The objective of this study was to evaluate the association between me...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2011.02.003
更新日期：2011-05-01 00:00:00
abstract：:Pleasant interior space is essential for modern people who spend considerably more time in the buildings than they did in the past. To achieve this, one aspect includes an ambient temperature that maintains the thermal equilibrium of the human body. The construction of wood framed buildings is becoming increasingly po...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2019.03.049
更新日期：2019-06-01 00:00:00
abstract：:No nationwide study has ever measured polychlorinated biphenyl (PCB) and organochlorine pesticide (OCP) body burden in Canadians aged 65 years and over. The objective of this study was to determine plasma concentrations of PCB congeners and OCPs in participants from a sub-cohort of the Canadian Study of Health and Agi...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2011.09.017
更新日期：2011-11-01 00:00:00
abstract：:Although the anti-knocking agents used in Taiwan do not contain manganese, there are relatively high concentrations of the element in diesel fuel. As such, there have been many concerns about the impact of exposure to diesel fuels on health. This study was conducted in Taiwan to investigate the relationship between th...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2011.01.001
更新日期：2011-02-01 00:00:00
abstract：:Several studies have demonstrated that millions of people globally are potentially exposed to volcanic gases. Hydrogen sulfide is a typical gas in volcanic and geothermal areas. The gas is toxic at high concentrations that predominantly affects the nervous, cardiovascular, and respiratory systems. The WHO air quality ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2010.05.009
更新日期：2010-08-01 00:00:00
abstract：BACKGROUND:Many women who smoke tobacco continue to do so during lactation, and many non-smoking women are exposed to second-hand tobacco smoke (SHS) during the period that she wishes to breastfeed. There are reports documenting the adverse effects of maternal smoking during lactation on their infant's health; however,...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2018.12.017
更新日期：2019-03-01 00:00:00
abstract：BACKGROUND:Prenatal lead exposure has been reported to affect infant growth and nervous system development, as well as to influence DNA methylation. We conducted an epigenome-wide association study to identify associations between prenatal lead exposure and cord blood DNA methylation in Korean infants. METHODS:Cord bl...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2021.110767
更新日期：2021-01-27 00:00:00
abstract：:Variation in individual susceptibility to arsenic-induced disease may be partially explained by genetic differences in arsenic metabolism. Mounting epidemiological evidence and in vitro studies suggest that methylated arsenic metabolites, particularly monomethylarsonic (MMA3), are more acutely toxic than inorganic ars...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2010.05.001
更新日期：2010-08-01 00:00:00
abstract：:We attempted to develop a brief test battery to assess mental state for use in occupational health care settings. As a first step, we focused on the following three psychosocial aspects: ego state, behavioral pattern, and mood state which were considered to be closely related to mental state. To evaluate these paramet...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1006/enrs.1993.1073
更新日期：1993-05-01 00:00:00
abstract：:Gold nanorods (AuNRs) are promising nanoscale materials for several technological and biomedical applications. The physicochemical properties of AuNRs, including size, shape and surface features, are crucial factors affecting their cytotoxicity. In this study, we investigated the effects of different aspect ratios of ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.110133
更新日期：2020-12-01 00:00:00
abstract：:We examined relationships between trace metal concentrations in tissues of common eider ducks (cadmium, mercury, and selenium) and selected biomarkers of health (stress response, immune function, and body condition). This study was conducted at an eider nesting colony in the Canadian arctic in 1998 and 1999. Capture-i...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1006/enrs.2002.4384
更新日期：2002-09-01 00:00:00
abstract：:Biochemical alterations in guinea pig lungs caused by hematite dust were followed at 150 days after intratracheal administration of the dust. In vivo dust exposure caused a significant increase in mitochondrial protein content and cytochrome c oxidase activity whereas diaphorase activity remained unaltered. Mitochondr...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/0013-9351(83)90119-6
更新日期：1983-12-01 00:00:00
abstract：:Minamata disease is methyl mercury intoxication from fish contaminated by a chemical factory in Minamata city. Based on the results of our regional survey, cardinal clinical features of the disease were clarified by a multivariant analysis of all symptoms in inhabitants in the polluted area. The clinical features were...
journal_title：Environmental research
pub_type： 杂志文章,评审
doi：10.1006/enrs.1993.1137
更新日期：1993-10-01 00:00:00
abstract：:In 1992, the U.S. Congress passed the Residential Lead-Based Paint Hazard Reduction Act, which requires the promulgation of health-based dust lead and soil lead standards for residential dwellings to prevent undue lead exposure in children. Unfortunately, the levels of lead in house dust and soil that are associated w...
journal_title：Environmental research
pub_type： 杂志文章,meta分析
doi：10.1006/enrs.1998.3859
更新日期：1998-10-01 00:00:00
abstract：BACKGROUND:Polybrominated diphenyl ethers (PBDEs) have been phased out of production for nearly a decade yet are still frequently detected in serum of U.S. adults. PBDE concentrations have been associated with adverse reproductive outcomes and laboratory studies suggest hydroxylated-BDEs (OH-BDEs) may act as endocrine ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.110226
更新日期：2021-01-01 00:00:00
abstract：:The increased nitrogen (N) fertilizer usage caused substantial nitrate (NO3-) leaching into groundwater and eutrophication in downstream aquatic systems. Riparian zones positioned as the link interfaces of terrestrial and aquatic environments are effective in NO3- removal. However, the microbial mechanisms regulating ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2019.108867
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND:Endocrine disrupting industrial chemicals, such as polychlorinated biphenyls (PCBs), are suspected to adversely affect male reproductive functions. OBJECTIVES:The Faroe Islands community exhibits an unusually wide range of exposures to dietary contaminants, and in this setting we examined the possible assoc...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2015.02.030
更新日期：2015-04-01 00:00:00
abstract：:The arid region of Northwest China, located in the central Asia, responds sensitively to global climate change. Based on the newest research results, this paper analyzes the impacts of climate change on hydrology and the water cycle in the arid region of Northwest China. The analysis results show that: (1) In the nort...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2014.12.029
更新日期：2015-05-01 00:00:00
abstract：BACKGROUND:It is unknown if higher levels of ambient particulate matter (PM) exposure increase the risk for premature ventricular contractions (PVC) in a population-based study of men and women, and if this relationship varies by race or sex. METHODS:We examined the association of PM <2.5µm in diameter (PM2.5) concent...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2016.12.031
更新日期：2017-04-01 00:00:00
abstract：:We developed a high throughput analytical method using on-line solid phase extraction coupled with isotope dilution high-performance liquid chromatography-tandem mass spectrometry (on-line SPE-HPLC-MS/MS) to simultaneously determine the concentrations of 17 polyfluoroalkyl chemicals (PFCs) in house dust. The sample pr...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2009.01.005
更新日期：2009-07-01 00:00:00
abstract：:Mild gasification of coal is a technology being developed in the United States in order to upgrade lower rank coals and facilitate their use in coal-burning electric generation plants. Thirteen coal-derived mild gasification products from different coal sources and processing conditions have been examined for their po...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1006/enrs.1996.3676
更新日期：1997-01-01 00:00:00
abstract：:This study characterized nitrate-nitrogen (NO3-N) concentrations in groundwater and stream water in an agricultural head watershed in South Korea and identified the pollution load of NO3-N as a result of the groundwater entering streams using field surveys, analyses of chemical constituents, and numerical modeling. Th...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.109313
更新日期：2020-05-01 00:00:00
abstract：:Pharmaceuticals are designed to have physiological effects on target organisms. Their presence and effect in aquatic ecosystems in the Annapolis Valley in Nova Scotia is relatively unknown. Over-the-counter (OTC) and prescription drugs are continually introduced to aquatic ecosystems through treated sewage effluent ou...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2011.11.011
更新日期：2012-01-01 00:00:00
abstract：:Endocrine disrupting chemicals (EDCs) from the environment are associated with reproductive abnormalities (i.e. decreased sperm concentration; increased endometriosis) and alterations of the cardiovascular system (i.e. increased blood pressure and risk of coronary disease). Some phthalates esters have been identified ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2017.11.039
更新日期：2018-02-01 00:00:00
abstract：:Simulating allergenic tree pollen is important to protect sensitive population and to support bioaerosols monitoring effort. Using the regional air quality model GEM-MACH, a simulation was conducted adopting two new main hypotheses: 1) the use of vertical correlation concept to force the vertical dispersion (a method ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.110554
更新日期：2020-12-03 00:00:00
abstract：:Nitrogen dioxide (NO2) and black carbon (BC) concentrations were measured inside London taxicabs across 40 work shifts in a real-world occupational study. The shifts were measured across five plug-in hybrid range-extender electric taxicabs (TXe City) and five diesel taxicabs (TX4 Diesel). The aim of this study was to ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2021.110736
更新日期：2021-01-20 00:00:00
abstract：:The studies on the effects of phenol (P), 2,4-dinitrophenol (DNP), pentachlorophenol (PCP) individually and in three combinations, viz., (PCP + DNP)/P (highly antagonistic), (DNP + P)/PCP (additive), and (P + DNP)/PCP (highly synergistic), at three sublethal levels (1/10, 1/15, and 1/20 of the 96-hr LC50) on the activ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/s0013-9351(87)80195-0
更新日期：1987-04-01 00:00:00
abstract：:OMS-2 is one of the most promising catalysts for carcinogenic benzene elimination, and single-type alkali metals are typically introduced into the OMS-2 tunnels to modify its catalytic activity. Here, we reported a novel approach for significantly increasing the catalytic activity of OMS-2 via the simultaneous introdu...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.110146
更新日期：2020-12-01 00:00:00
