Abstract:
:The association of the STH gene polymorphism with Alzheimer disease (AD) is debated. In the analysis of two genetically and diagnostically distinct groups of Alzheimer patients from the USA and Italy, the authors did not find an association with the STH polymorphism. However, the APOE-4-associated risk of AD greatly increased if the STH-G allele was also present. The STH-G allele appears to be a risk modifier for AD.
journal_name
Neurologyjournal_title
Neurologyauthors
Seripa D,Matera MG,D'Andrea RP,Gravina C,Masullo C,Daniele A,Bizzarro A,Rinaldi M,Antuono P,Wekstein DR,Dal Forno G,Fazio VMdoi
10.1212/01.wnl.0000125693.59817.31subject
Has Abstractpub_date
2004-05-11 00:00:00pages
1631-3issue
9eissn
0028-3878issn
1526-632Xjournal_volume
62pub_type
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