Abstract:
BACKGROUND:A broad differential diagnosis has to be considered in a patient with swollen discs. Myeloproliferative disorders such as leukemia and lymphoma can in rare cases cause infiltrative optic neuropathy. HISTORY AND SIGNS:Two patients initially presented with slowly progressive severe visual loss. History was unremarkable except for previously noted slightly elevated white blood cell count for which - according to their general physicians - no treatment or work-up was required. At presentation, bilateral disc swelling was present. Magnetic resonance imaging showed enhancement of the entire optic nerves sparing the chiasm. No other intracranial lesion was found. Cerebrospinal fluid contained no malignant cells. THERAPY AND OUTCOME:After bone marrow aspiration the diagnosis of non-Hodgkin's lymphoma and granulocytic leukemia, respectively, was made. Treatment resulted in visual recovery. CONCLUSION:Work-up in a patient with swollen discs should always include white blood cell count. If the result is abnormal further exploration should be pursued. Elevated white blood cell count may be the only hint of optic nerve infiltration caused by a myeloproliferative disorder and its treatment can result in remarkable recovery.
journal_name
Klin Monbl Augenheilkdjournal_title
Klinische Monatsblatter fur Augenheilkundeauthors
Wirth MG,Bergamin O,Goede JS,Landau Kdoi
10.1055/s-2004-812857subject
Has Abstractpub_date
2004-05-01 00:00:00pages
360-3issue
5eissn
0023-2165issn
1439-3999journal_volume
221pub_type
杂志文章abstract::A report is given on seventeen cases of spontaneous regression of diabetic retinopathy. The diabetes became manifest, without exception, at an early age, particularly in childhood. Regression came on slowly and inconspicuously, retinopathy disappearing completely in two thirds of the cases. Of the other forms of diabe...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1976-11-01 00:00:00
abstract::Fodrin, a member of the spectrin family, is abundantly found in brain and lens. Based on its often observed peripheral cellular distribution, it is generally believed that fodrin - like other spectrins - participates in the linkage of membrane components to cytoskeletal elements providing their anchorage to distinct, ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1045994
更新日期:1991-05-01 00:00:00
abstract:PURPOSE:A peripheral iridotomy (PI) is the treatment of choice for pupillary block. In this study we investigated the effect of enlarging the size of a small PI on the anterior chamber angle in patients with angle closure using ultrasound biomicroscopy (UBM). PATIENTS AND METHODS:Patients who had been treated with las...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1027249
更新日期:2008-05-01 00:00:00
abstract::The histological and ultrastructural findings in the ciliary ganglion of glaucomatous patients show proliferation of the satellite cells, vacuolate degeneration of the cytoplasma with loss of the mitochondria and ergastoplasma, and necrosis of the nucleus with decrease of chromatin. ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050838
更新日期:1986-11-01 00:00:00
abstract::36 malignant tumours of the eyelids (basaliomas, basal-cell carcinomas and squamous-cell carcinomas) have been treated by intrapalpebral injections of a 5% to 25% solution of urea as recommended by E.D. Danopoulos. 1.5 to 3.0 ml of the solutions were injected around the tumours twice per week. Six malignant tumours di...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1976-07-01 00:00:00
abstract:BACKGROUND:Non-neovascular age-related macular degeneration (AMD) is not yet treatable. This article summarises current clinical research approaches. The reasons for the current lack of success are analysed. METHODS:Literature and databank search. RESULTS:The number of therapeutic approaches and mechanisms is limited...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/a-0914-3183
更新日期:2019-09-01 00:00:00
abstract::Thirty patients with ocular hypertension or open-angle glaucoma were tested to see if, and to what extent, guanethidine/dipivefrin and pilocarpine produced a supplementary reduction in intraocular pressure. An equally marked additional lowering of pressure was achieved when patients who had been given guanethidine/dip...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050337
更新日期:1987-02-01 00:00:00
abstract:INTRODUCTION:The aim of this study was to differentiate the pressure-reducing results following trabecular aspiration combined with small incision cataract surgery in eyes with pseudoexfoliation depending on preoperative pressure and medication score. PATIENTS AND METHODS:A retrospective analysis was made of 104 exfol...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0031-1282014
更新日期:2012-06-01 00:00:00
abstract::From the results of 628 operations on strabismus convergens, the individual corrections were related to the achieved reduction of the angle of deviation. The evaluation showed that strabismus operations may be well dosed not only with a view to a general improvement of the squint angle but also as a specific influence...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1975-08-01 00:00:00
abstract:PATIENTS AND METHODS:In 28 patients after perforating keratoplasty followed by epithelial abrasion of the transplant the period required for epithelial closure with a therapy including collagen shields and the growth stimulating factors vitamin A and Epidermal Growth Factor (EGF) was determined. RESULTS:A significant ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1055/s-2008-1045517
更新日期:1994-10-01 00:00:00
abstract::Descemetʼs membrane detachment (DMD) is a rare complication following cataract and glaucoma surgery as well as lamellar graft procedures. DMD can lead to blurry vision, halos and severe visual loss. Clinically, when there is a large central detachment, a double anterior chamber is seen to form. In this scenario, surgi...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0032-1328333
更新日期:2013-04-01 00:00:00
abstract::Using the laser flare-cell meter (LFMC), we have previously determined the intensity and pattern of post-ALT ocular inflammation. Inflammation peak occurs 48 hours after ALT and clinically relevant inflammation is seen in 100% of pigmentary glaucomas (PIG), 75% of pseudoexfoliative glaucomas (PEXG) but only in 25% of ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1055/s-2008-1045765
更新日期:1992-05-01 00:00:00
abstract::Real-time tracking of eye movements offers a solution to various problems in ophthalmology. Different types of image analysis and processing techniques is discussed and an advanced pattern recognition eye-tracking system has been developed; it can track a retinal target (in real time) under conditions typical for opht...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050488
更新日期:1987-08-01 00:00:00
abstract::The indications for anterior vitrectomy are presented and the surgical technique is described. An analysis is made of the results of anterior vitrectomy in 93 eyes followed for 4 years and compared with the results of a previous study in which vitreous loss was treated more conservatively. The results of anterior vitr...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1977-06-01 00:00:00
abstract::Background Until now, many studies have investigated the link between motor development and visual-spatial abilities in infancy and childhood. Most of these studies found evidence that there is such a link in typically developing children or children with locomotor delay. Only a few studies have tested the consequence...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0043-118831
更新日期:2017-10-01 00:00:00
abstract:INTRODUCTION:Our study compares the biomechanical properties of the cornea in patients with long-term pre-existing (for at least 10 years) systemic sclerosis (SSc) with those of healthy suspects. MATERIAL/METHODS:The examination was performed in 14 systemic SSc patients and 38 healthy volunteers. Non-invasive assessme...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0043-125078
更新日期:2019-06-01 00:00:00
abstract::A recently developed sound probe (10 MHz and 3 mm diameter) is suitable for sparing preoperative localisation of foreign bodies in perforated eyes; especially mural foreign bodies can be exactly located intraoperatively. Followed scleral incision foreign bodies can be extracted on the optimal route. ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1978-02-01 00:00:00
abstract:BACKGROUND:The diagnosis of idiopathic intracranial hypertension results from a synopsis of standardised examinations including MRI. Since the cerebrospinal fluid pressure influences the pressure of the central retinal vein, it was the purpose of the present study to evaluate whether the ophthalmodynamometric estimatio...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2007-963634
更新日期:2007-11-01 00:00:00
abstract::Two separate lenses were found in the right eye of a 9-year-old boy who underwent surgery for bilateral cataracta congenita perinuclearis. No other ocular anomalies were observed. ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1054890
更新日期:1983-08-01 00:00:00
abstract::Correct differential diagnosis in cases of blurred optic disc margins is a challenging task for ophthalmologists. The reliable differentiation of pseudopapilloedema and true papilloedema has significant implications for proper patient management. Conditions that give rise to pseudopapilloedema include small crowded di...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-0043-108489
更新日期:2017-06-01 00:00:00
abstract::In 14 out of 25 patients with retinoblastoma there was a family history of malignancies. Most of the malignant tumours had been carcinomas. In 2 families relatives died because of leukaemia; in these cases the tumour was a so-called diffuse retinoblastoma occurring in elder children. A third family with a retinoblasto...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1976-05-01 00:00:00
abstract::A new treatment of a case of scleromalacia perforans, complicating rheumatoid arthritis is reported. To save the eye fascia lata was transplanted, preoperatively prednisolone and d-penicillamine was started, and this therapy was continued for one year thereafter. The effect was favorable, as pains vanished, and the gr...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1975-09-01 00:00:00
abstract::A new measuring system for echo return times is described, which renders it possible to measure simultaneously the three axial lengths of the living eye (length of cornea plus anterior chamber, length of the lens and of the vitreous) with ultrasound in real time and to process the data numerically. The repetition rate...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1057620
更新日期:1980-07-01 00:00:00
abstract::Optic neuritis is a frequent neuro-ophthalmological disease in which the diagnosis can be based on just a few symptoms and findings. It is not only important to differentiate from other optic nerve disorders but also to recognise special types of optic neuritis, which is mostly only possible during the course of the d...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-0034-1382930
更新日期:2014-11-01 00:00:00
abstract::In everyday practice, intravitreal therapy in an "as needed" regimen (pro re nata, PRN) is less predictable and requires more visits (monitoring and injections taken together) with poorer functional results than with the treat and extend (T&E) regimen. Current literature supports the benefit of a switch. However, prac...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-0042-118184
更新日期:2018-01-01 00:00:00
abstract::On account of the good results with the new generation of anterior chamber lenses reported by C.D. Binkhorst, the implantation of lenses was begun in 1969 at the Department of Ophthalmology in Bremen and 350 anterior chamber lenses were implanted till 1st Febr. 1977. After the presentation of indications and the opera...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:
更新日期:1978-03-01 00:00:00
abstract::A case of probably not congenital dissociated pendular nystagmus is reported in which on the contrary to similar published cases no neurological disorder is present. ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1975-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:With the discrepancy between availability and demand for corneal donors, the purpose of our study was to identify significant factors influencing the suitability and affecting the main reasons for discarding organ-cultured corneas. We thus aimed to minimise the percentage of unsuitable corneas in...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/a-1141-3703
更新日期:2020-11-01 00:00:00
abstract::Diabetic macular edema (DME) and proliferative retinopathy are common causes for blindness in middle-aged patients. The gold standard for treatment has been laser coagulation. Limitations of this therapy are refractive DME, ischaemic diabetic maculopathy and complications after laser application. The need for a non-de...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-0029-1245718
更新日期:2010-09-01 00:00:00
abstract::Network analysis of the human retinal vessels must be based on a thorough knowledge of the topology of the network. This derives from the numerical composition of the network's individual components. Using histologic specimens, centrifugal and centripetal ordering methods were compared. It was found necessary to use a...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1046240
更新日期:1990-07-01 00:00:00