The clinical application of research utilization: amphotericin B.

Abstract:

PURPOSE/OBJECTIVES:To describe the first application of the research utilization process by clinical nurses using the Stetler-Marram Model of Research Utilization to the practice of amphotericin B administration; to share the findings; and to discuss issues encountered in the process and their solutions. DATA SOURCES:Published articles identified through computerized literature searches, published abstracts and books, personal communication with one author, and an informal survey of other cancer centers' amphotericin B infusion practices; research articles were selected for review if studies included settings and patient populations similar to those of the authors and if they used experimental designs. DATA SYNTHESIS:Studies were reviewed for scientific merit and clinical applicability according to the Stetler-Marram model; findings were used to develop a specific nursing protocol for infusion times of amphotericin B based on clinical criteria. CONCLUSIONS:The Stetler-Marram model helped staff nurses decide how to apply research findings to practice, although using it was difficult and required mentorship. A research base exists for amphotericin B administration time but not for test doses or premedications to prevent or minimize side effects. IMPLICATIONS FOR NURSING PRACTICE:Staff nurses can use the Stetler-Marram model but need resources and support from individuals, committees, and administration. A specific protocol representing a practice change was implemented and may be applicable to other settings.

journal_name

Oncol Nurs Forum

journal_title

Oncology nursing forum

authors

Reedy AM,Shivnan JC,Hanson JL,Haisfield ME,Gregory RE

subject

Has Abstract

pub_date

1994-05-01 00:00:00

pages

715-9

issue

4

eissn

0190-535X

issn

1538-0688

journal_volume

21

pub_type

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