A fluorescein angiographic study of patients with pars planitis and peripheral exudation (snowbanking) before and after cryopexy.

Abstract:

BACKGROUND:Transconjunctival cryopexy of the vitreous base is clinically effective in patients with steroid nonresponsive pars planitis who have peripheral neovascularization. Cryoablation of the region previously has been thought to eliminate the areas of permeable neovascular tissue, thus removing the focus of exudation. The authors report the first study of patients with refractory pars planitis in which fluorescein angiography of the inferior pars plana snowbanks was performed both before and after cryopexy of the vitreous base. METHODS:Twelve consecutive phakic eyes with pars planitis and prominent peripheral snowbanks had fluorescein angiograms of the pars plana. Clinical involvement was graded on the basis of visual acuity, levels of vitreous inflammation and cystoid macular edema, and on the extent of peripheral snowbanking. Transconjunctival cryopexy of the vitreous base was performed. Fluorescein angiography of the pars plana snowbanks was repeated 2 months after the procedure, and clinical involvement again was graded. RESULTS:Early hyperfluorescence with late leakage was present in all eyes and was limited to the area of the pars plana snowbanks. After cryopexy of the vitreous base, all eyes demonstrated hypofluorescence and diminution of late-phase dye leakage in the treated areas. Eighty-three percent of all eyes demonstrated clinical improvement, consistent with previously reported studies. CONCLUSION:Cryopexy of the vitreous base decreases peripheral exudation in patients with refractory pars planitis and snowbanking. This suggests that elimination of peripheral neovascular tissue may be directly related to clinical improvement in these patients.

journal_name

Ophthalmology

journal_title

Ophthalmology

authors

Josephberg RG,Kanter ED,Jaffee RM

doi

10.1016/s0161-6420(13)31726-6

subject

Has Abstract

pub_date

1994-07-01 00:00:00

pages

1262-6

issue

7

eissn

0161-6420

issn

1549-4713

pii

S0161-6420(94)31180-8

journal_volume

101

pub_type

杂志文章
  • Efficacy and Safety of Intravitreal Sirolimus for Noninfectious Uveitis of the Posterior Segment: Results from the Sirolimus Study Assessing Double-Masked Uveitis Treatment (SAKURA) Program.

    abstract:PURPOSE:To evaluate the efficacy and safety of intravitreal sirolimus in the management of noninfectious uveitis of the posterior segment (NIU-PS). DESIGN:Combined analysis of 2 phase 3, randomized, double-masked, multinational, 6-month studies. PARTICIPANTS:Adults with active NIU-PS (intermediate uveitis, posterior ...

    journal_title:Ophthalmology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ophtha.2020.03.033

    authors: Merrill PT,Clark WL,Banker AS,Fardeau C,Franco P,LeHoang P,Ohno S,Rathinam SR,Ali Y,Mudumba S,Shams N,Nguyen QD,Sirolimus Study Assessing Double-Masked Uveitis Treatment (SAKURA) Study Group.

    更新日期:2020-10-01 00:00:00

  • Dacryoadenoma. A unique tumor of the conjunctival epithelium.

    abstract::For 15 years, a 48-year-old woman had been aware of a pinkish translucent inferior epibulbar mass toward the fornix that was stationary in size. Light microscopic evaluation of the excised specimen showed that it was a gland-forming benign tumor. It originated from the surface epithelium by the downward invagination o...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(89)32799-0

    authors: Jakobiec FA,Perry HD,Harrison W,Krebs W

    更新日期:1989-07-01 00:00:00

  • Electroretinographic findings in the mucopolysaccharidoses.

    abstract::The degree of retinal involvement of 20 patients (ages 3-21) with mucopolysaccharidosis (MPS) types I, II, and III was assessed using electroretinography (ERG) under standardized conditions. ERG evidence of retinal dysfunction ranged from none to severe in MPS I and II, and from moderate to severe in MPS III. The ERG ...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(86)33537-1

    authors: Caruso RC,Kaiser-Kupfer MI,Muenzer J,Ludwig IH,Zasloff MA,Mercer PA

    更新日期:1986-12-01 00:00:00

  • Annular peripheral choroidal detachment simulating aqueous misdirection after glaucoma surgery.

    abstract:PURPOSE:The purpose of the study was to define a newly recognized complication after glaucoma surgery and to recommend a therapeutic regimen. METHODS:Eighteen patients diagnosed initially as having aqueous misdirection after glaucoma surgery, but who subsequently were found by ultrasonography to have an annular periph...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(97)30294-2

    authors: Dugel PU,Heuer DK,Thach AB,Baerveldt G,Lee PP,Lloyd MA,Minckler DS,Green RL

    更新日期:1997-03-01 00:00:00

  • Primary Open-Angle Glaucoma Suspect Preferred Practice Pattern(®) Guidelines.

    abstract:UNLABELLED:PRIMARY OPEN-ANGLE GLAUCOMA SUSPECT PREFERRED PRACTICE PATTERN® GUIDELINES:Evidence-based update of the Primary Open-Angle Suspect Glaucoma Preferred Practice Pattern® (PPP) guidelines, describing the diagnosis and management of patients with primary open-angle glaucoma suspect with detailed recommendations...

    journal_title:Ophthalmology

    pub_type: 杂志文章,实务指引

    doi:10.1016/j.ophtha.2015.10.055

    authors: Prum BE Jr,Lim MC,Mansberger SL,Stein JD,Moroi SE,Gedde SJ,Herndon LW Jr,Rosenberg LF,Williams RD

    更新日期:2016-01-01 00:00:00

  • Ocular findings in patients with polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes syndrome.

    abstract:OBJECTIVE:Polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome is a rare disorder. This study investigated the types of ocular signs and symptoms in patients with POEMS and any systemic factors that may be associated with development of such ocular findings. DESIGN:Cas...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2010.08.013

    authors: Kaushik M,Pulido JS,Abreu R,Amselem L,Dispenzieri A

    更新日期:2011-04-01 00:00:00

  • Fluorescein angiography versus optical coherence tomography for diagnosis of uveitic macular edema.

    abstract:OBJECTIVE:To evaluate agreement between fluorescein angiography (FA) and optical coherence tomography (OCT) results for diagnosis of macular edema in patients with uveitis. DESIGN:Multicenter cross-sectional study. PARTICIPANTS:Four hundred seventy-nine eyes with uveitis from 255 patients. METHODS:The macular status...

    journal_title:Ophthalmology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ophtha.2013.01.069

    authors: Kempen JH,Sugar EA,Jaffe GJ,Acharya NR,Dunn JP,Elner SG,Lightman SL,Thorne JE,Vitale AT,Altaweel MM,Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group.

    更新日期:2013-09-01 00:00:00

  • The prevalence and natural history of dominant optic atrophy due to OPA1 mutations.

    abstract:PURPOSE:Autosomal dominant optic atrophy (DOA) is a major cause of visual impairment in young adults that is characterized by selective retinal ganglion cell loss. To define the prevalence and natural history of this optic nerve disorder, we performed a population-based epidemiologic and molecular study of presumed DOA...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2009.12.038

    authors: Yu-Wai-Man P,Griffiths PG,Burke A,Sellar PW,Clarke MP,Gnanaraj L,Ah-Kine D,Hudson G,Czermin B,Taylor RW,Horvath R,Chinnery PF

    更新日期:2010-08-01 00:00:00

  • Ophthalmologic findings in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy: a cross-sectional study.

    abstract:OBJECTIVE:To determine the ophthalmologic findings, especially the nature of retinal vascular changes, and their clinical significance in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), a disease that causes migraine, recurrent strokes, and finally subcortical vascu...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2006.03.030

    authors: Roine S,Harju M,Kivelä TT,Pöyhönen M,Nikoskelainen E,Tuisku S,Kalimo H,Viitanen M,Summanen PA

    更新日期:2006-08-01 00:00:00

  • Eyelid retraction, lid lag, lagophthalmos, and von Graefe's sign quantifying the eyelid features of Graves' ophthalmopathy.

    abstract:PURPOSE:To report the frequency and relationship of eyelid retraction, lid lag, lagophthalmos, and von Graefe's sign in a group of patients with Graves' ophthalmopathy and compare these findings to those in a group of normal individuals. DESIGN:Retrospective comparative cohort study. PARTICIPANTS:Fifty consecutive Gr...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2007.07.027

    authors: Gaddipati RV,Meyer DR

    更新日期:2008-06-01 00:00:00

  • Vision-Related Quality of Life Associated with Unilateral and Bilateral Ocular Conditions.

    abstract:PURPOSE:To present ophthalmic patient time-tradeoff vision utilities for quantifying vision-related quality-of-life when the fellow eye still has good vision. These utilities are important for performing reliable cost-utility analyses. DESIGN:Consecutive time-tradeoff vision utilities were obtained from ophthalmic pat...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2017.12.033

    authors: Brown GC,Brown MM,Stein JD,Smiddy WE,Ophthalmic Utility Research Study Group.

    更新日期:2018-07-01 00:00:00

  • Age and gender variations in age-related macular degeneration prevalence in populations of European ancestry: a meta-analysis.

    abstract:OBJECTIVE:To obtain prevalence estimates of age-related macular degeneration (AMD; late, geographic atrophy, neovascular) by age and gender amongst populations of European ancestry taking into account study design and time trends. DESIGN:Systematic review of population-based studies published by September 2010 with qu...

    journal_title:Ophthalmology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.ophtha.2011.09.027

    authors: Rudnicka AR,Jarrar Z,Wormald R,Cook DG,Fletcher A,Owen CG

    更新日期:2012-03-01 00:00:00

  • Risk factors for conversion to neovascular age-related macular degeneration based on longitudinal morphologic and visual acuity data.

    abstract:PURPOSE:To use longitudinal quantitative morphologic and visual acuity (VA) data to investigate the risk of choroidal neovascularization (CNV) event occurrence in eyes with dry age-related macular degeneration (AMD). DESIGN:Prospective observational study. PARTICIPANTS:A total of 513 participants (844 eyes) followed ...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2012.02.048

    authors: Friberg TR,Bilonick RA,Brennen PM

    更新日期:2012-07-01 00:00:00

  • Intraretinal leakage of indocyanine green dye.

    abstract:PURPOSE:Indocyanine green (ICG) dye is known to remain selectively in and around choroidal neovascularization (CNV) associated with age-related macular degeneration, and is thought to be cleared from the overlying retinal circulation without leakage. This is the basis of ICG dye-enhanced laser photocoagulation. The aut...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(94)31323-6

    authors: Ho AC,Yannuzzi LA,Guyer DR,Slakter JS,Sorenson JA,Orlock DA

    更新日期:1994-03-01 00:00:00

  • A primate model of macular cyst.

    abstract::Perfluoropropane (C3F8) was injected into nine eyes of six cynomolgus monkeys. In all nine eyes, macular changes consistent with the development of a macular cyst were noted within 3 months after injection. On fluorescein angiography, there was no evidence of retinal vascular leakage associated with the macular cysts....

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(91)32259-0

    authors: Repka MX,Bressler NM,D'Anna SA

    更新日期:1991-04-01 00:00:00

  • Follow-up to Age 4 Years of Treatment of Type 1 Retinopathy of Prematurity Intravitreal Bevacizumab Injection versus Laser: Fluorescein Angiographic Findings.

    abstract:PURPOSE:To compare structural outcome at age 4 years of eyes treated with intravitreal injection of bevacizumab with fellow eyes treated with conventional laser photoablation in type 1 retinopathy of prematurity (ROP). DESIGN:Single, randomized, controlled trial. PARTICIPANTS:All inborn babies with type 1 zone 1 ROP ...

    journal_title:Ophthalmology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ophtha.2017.08.005

    authors: Lepore D,Quinn GE,Molle F,Orazi L,Baldascino A,Ji MH,Sammartino M,Sbaraglia F,Ricci D,Mercuri E

    更新日期:2018-02-01 00:00:00

  • Progression of Geographic Atrophy in Age-related Macular Degeneration: AREDS2 Report Number 16.

    abstract:PURPOSE:To analyze the prevalence, incidence, and clinical characteristics of eyes with geographic atrophy (GA) in age-related macular degeneration (AMD), including clinical and genetic factors affecting enlargement. DESIGN:Prospective cohort study within a controlled clinical trial. PARTICIPANTS:Age-Related Eye Dise...

    journal_title:Ophthalmology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ophtha.2018.05.028

    authors: Keenan TD,Agrón E,Domalpally A,Clemons TE,van Asten F,Wong WT,Danis RG,Sadda S,Rosenfeld PJ,Klein ML,Ratnapriya R,Swaroop A,Ferris FL 3rd,Chew EY,AREDS2 Research Group.

    更新日期:2018-12-01 00:00:00

  • Evaluation of a patient with central retinal vein occlusion.

    abstract::Patients suffering a central retinal vein occlusion should be evaluated for conditions that promote and/or contribute to the formation of a thrombosis in the central retinal vein. These conditions include alterations of blood flow, altered viscosity of the blood, abnormalities of coagulation, and abnormalities of vess...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(83)34528-0

    authors: Gutman FA

    更新日期:1983-05-01 00:00:00

  • Poorer neurodevelopmental outcomes associated with cystoid macular edema identified in preterm infants in the intensive care nursery.

    abstract:PURPOSE:To evaluate the association between cystoid macular edema (CME) observed in very preterm infants and developmental outcomes at 18 to 24 months corrected age. DESIGN:Cohort study. PARTICIPANTS:Infants born at or less than 1500 g or at or less than 30 weeks postmenstrual age who underwent screening for retinopa...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2014.09.022

    authors: Rothman AL,Tran-Viet D,Gustafson KE,Goldstein RF,Maguire MG,Tai V,Sarin N,Tong AY,Huang J,Kupper L,Cotten CM,Freedman SF,Toth CA

    更新日期:2015-03-01 00:00:00

  • Boston Keratoprosthesis: Outcomes and Complications: A Report by the American Academy of Ophthalmology.

    abstract:OBJECTIVE:To review the published literature on safety and outcomes of the Boston type I keratoprosthesis (BI-KPro) for the surgical treatment of corneal opacification not amenable to human cadaveric corneal transplantation. METHODS:Searches of peer-reviewed literature were conducted in PubMed and the Cochrane Library...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2015.03.025

    authors: Lee WB,Shtein RM,Kaufman SC,Deng SX,Rosenblatt MI

    更新日期:2015-07-01 00:00:00

  • Long-term follow-up of trabeculectomy with intraoperative 5-fluorouracil for uveitis-related glaucoma.

    abstract:PURPOSE:To determine the effect of intraoperative application of 5-fluorouracil (5-FU) on the long-term outcome of trabeculectomy in uveitis-related glaucoma. DESIGN:An open, prospective, noncomparative case study to evaluate the use of intraoperative application for 5 minutes of 25 mg/ml 5-FU in primary trabeculectom...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(00)00351-1

    authors: Towler HM,McCluskey P,Shaer B,Lightman S

    更新日期:2000-10-01 00:00:00

  • Rapid growth of an optic nerve ganglioglioma in a patient with neurofibromatosis 1.

    abstract:BACKGROUND:Optic nerve gangliogliomas are extremely rate tumors of the central nervous system composed of elements of glial and neuronal origin. The clinical and biologic behavior of gangliogliomas depends on the glial component. Pilocytic gangliogliomas generally have a low growth rate and good ultimate prognosis. No ...

    journal_title:Ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1016/s0161-6420(96)30613-1

    authors: Sadun F,Hinton DR,Sadun AA

    更新日期:1996-05-01 00:00:00

  • Normal endothelial cell count range.

    abstract::It was the purpose of this study to determine whether age could be used to predict central endothelial cell count in preoperative cataract patients aged 40 to 90. Three separate series of cell counts on a total of almost 3,000 eyes were performed and analyzed regarding age relationship. Although statistically endothel...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(80)35149-x

    authors: Hoffer KJ,Kraff MC

    更新日期:1980-09-01 00:00:00

  • Outcomes of surgical bleb revision for complications of trabeculectomy.

    abstract:OBJECTIVE:To describe the results of revision surgery for complications of trabeculectomy in a case series from an academic glaucoma service. DESIGN:Retrospective case series. PARTICIPANTS:A total of 177 eyes of 167 adult patients who underwent revision of trabeculectomy at the Wilmer Eye Institute between 1994 and 2...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2009.04.003

    authors: Radhakrishnan S,Quigley HA,Jampel HD,Friedman DS,Ahmad SI,Congdon NG,McKinnon S

    更新日期:2009-09-01 00:00:00

  • Effects of laser in situ keratomileusis on tear production, clearance, and the ocular surface.

    abstract:PURPOSE:To evaluate components of the integrated ocular surface/lacrimal gland unit in a series of patients before and after undergoing bilateral laser in situ keratomileusis (LASIK). DESIGN:Prospective, noncomparative case series. PARTICIPANTS:Forty-eight eyes of 14 men and 34 women (age range, 26-54; mean, 39.2 yea...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(01)00623-6

    authors: Battat L,Macri A,Dursun D,Pflugfelder SC

    更新日期:2001-07-01 00:00:00

  • The management of corneal perforations associated with rheumatoid arthritis. An analysis of 32 eyes.

    abstract:BACKGROUND:Sterile corneal ulceration is a rare complication of rheumatoid arthritis and may lead to corneal perforation. Surgical management for visual restoration frequently is unsuccessful. The authors analyze the factors that may determine the failure of corneal surgery in perforations associated with rheumatoid ar...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(95)30867-6

    authors: Bernauer W,Ficker LA,Watson PG,Dart JK

    更新日期:1995-09-01 00:00:00

  • Toward zero effective phacoemulsification time using femtosecond laser pretreatment.

    abstract:OBJECTIVE:To compare effective phacoemulsification time after femtosecond laser pretreatment with conventional phacoemulsification and the associated effect on visual outcomes and endothelial cell loss. DESIGN:Prospective, consecutive, single-surgeon case-control study. CONTROLS:Controls underwent phacoemulsification...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2012.11.045

    authors: Abell RG,Kerr NM,Vote BJ

    更新日期:2013-05-01 00:00:00

  • Malakoplakia of the eyelid.

    abstract::A 35-year-old white man, on immunosuppressive medications for 3 1/2 years following a renal transplant, presented with a whitish-yellow mass at the medial end of the left lower eyelid. An initial incisional biopsy was performed that was misinterpreted as granular cell myoblastoma. The mass was subsequently excised and...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(86)33633-9

    authors: Addison DJ

    更新日期:1986-08-01 00:00:00

  • Ketorolac versus acetaminophen or ibuprofen in controlling postoperative pain in patients with strabismus.

    abstract:PURPOSE:Ketorolac is a new, parenteral, nonsteroidal, anti-inflammatory agent. The authors compare the effectiveness of a single intravenous dose of ketorolac with a single oral dose of either acetaminophen or ibuprofen in controlling postoperative pain in patients with strabismus. METHODS:A prospective, randomized, d...

    journal_title:Ophthalmology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0161-6420(94)31238-3

    authors: Morrison NA,Repka MX

    更新日期:1994-05-01 00:00:00

  • Presumed toxoplasmic papillitis.

    abstract::Six patients with ocular toxoplasmosis are described whose only active site of inflammation was at the optic nervehead. These patients presented with severe papillitis, vitreous inflammation, and sector or nerve fiber bundle field defects. Because of the papillitis and the absence of other typical foci of retinitis to...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(84)34329-9

    authors: Folk JC,Lobes LA

    更新日期:1984-01-01 00:00:00