A systematic-heuristic approach for space trajectory design.

abstract：:Accumulating epidemiological, clinical, and experimental evidence supports the conclusion of a critical role of epigenetic factors in immune programming. This understanding provides the basis for elucidating how the intricate interactions of the genome, epigenome, and transcriptome shape immune responses and maintain ...

journal_title：Annals of the New York Academy of Sciences

authors： Zouali M

更新日期：2011-01-01 00:00:00

abstract：:To improve safety and health in the workplace, appropriate occupational health programs should be implemented utilizing expertise from multiple disciplines. In other words, the occupational health program should be a team effort. Expertise from all aspects of occupational health should be utilized, from the industrial...

journal_title：Annals of the New York Academy of Sciences

authors： Murthy LI

更新日期：1997-12-26 00:00:00

abstract：:Thymosin β4 (Tβ4) is highly expressed in saliva of human newborns but not in adults. Here preliminary immunohistochemical analyses on different human tissues are reported. Immunoreactivity for Tβ4 in human salivary glands show high quantities of Tβ4 before birth, followed by downregulation of expression in adulthood. ...

journal_title：Annals of the New York Academy of Sciences

authors： Faa G,Nemolato S,Cabras T,Fanni D,Gerosa C,Fanari M,Locci A,Fanos V,Messana I,Castagnola M

更新日期：2012-10-01 00:00:00

abstract：:The apolipoprotein E (APOE) gene causes a major risk factor for the development of Alzheimer's disease (AD). To study the transcription control of the mouse (m) APOE gene, we first tested the promoter activity of a 721-base-pair (bp) 5'-flanking region, which is located 771 bp upstream from the translation initiation ...

journal_title：Annals of the New York Academy of Sciences

authors： Lahiri DK,Alley GM,Ge YW,Du Y

更新日期：2002-11-01 00:00:00

abstract：:The investigation of immune senescence has uncovered many changes in B cell development, maintenance, and function with increasing age. However, most of these studies have focused on conventional B cell subsets in the spleen. The B-1 cell subset is an essential arm of the innate immune system, which in general has bee...

journal_title：Annals of the New York Academy of Sciences

authors： Holodick NE,Rothstein TL

更新日期：2015-12-01 00:00:00

abstract：:This paper explores aspects of the role that laboratory instruments have played in establishing psychology as a science. Comparisons of earlier instruments with their more modern counterparts indicate that many problems and methods still of interest today were explored in the laboratories of psychology's pioneers. Suc...

journal_title：Annals of the New York Academy of Sciences

authors： Caudle FM

更新日期：1983-01-01 00:00:00

abstract：:A brief overview of the different techniques used to estimate the probable maximum precipitation (PMP) is presented. As a particular case, the 1-day PMP over Catalonia has been calculated and mapped with a high spatial resolution. For this purpose, the annual maximum daily rainfall series from 145 pluviometric station...

journal_title：Annals of the New York Academy of Sciences

authors： Casas MC,Rodríguez R,Nieto R,Redaño A

更新日期：2008-12-01 00:00:00

abstract：:A brief overview is presented of recently developed and currently emerging statistical and computational techniques that have been proved to be highly helpful in handling the avalanche of the new type of data generated by modern high-throughput technologies in experimental biology. The review, in no way comprehensive,...

journal_title：Annals of the New York Academy of Sciences

authors： Rosenfeld S

更新日期：2004-05-01 00:00:00

abstract：:Over seventy percent of unexpected infant deaths are registered as SIDS. Over 85,000 infants have been screened at birth and one month of age for risk of unexpected death using the Sheffield Score system. Scores range from below 400 to over 800 points. Infants with scores over 800 are at more than 16 times greater ris...

journal_title：Annals of the New York Academy of Sciences

authors： Carpenter RG,Gardner A,Harris J,Judd M,Lewry J,Maddock CR,Powell J,Taylor EM

更新日期：1988-01-01 00:00:00

abstract：:As the second synapse in the central gustatory pathway of the rodent, the parabrachial nucleus of the pons (PbN) receives information about taste stimuli directly from the nucleus of the solitary tract (NTS). Data show that NTS cells amplify taste responses before transmitting taste-related signals to the PbN. NTS cel...

journal_title：Annals of the New York Academy of Sciences

authors： Di Lorenzo PM,Platt D,Victor JD

更新日期：2009-07-01 00:00:00

abstract：:We have used site-directed mutagenesis to investigate the contributions of widely distributed residues in the thymosin beta-4 (Tbeta4) sequence to the formation and stability of the actin-Tbeta4 complex. Equilibrium and kinetic studies of actin binding were performed by monitoring the change in fluorescence of an N-io...

journal_title：Annals of the New York Academy of Sciences

authors： Au JK,De La Cruz EM,Safer D

更新日期：2007-09-01 00:00:00

abstract：:The incidence of autoimmune diseases is higher in females than in males. In both sexes, adrenal hormones, that is, glucocorticoids, dehydroepiandrosterone (DHEA), and androgens, are inadequately low in patients when compared to healthy controls. Hormonally active androgens are anti-inflammatory, whereas estrogens are ...

journal_title：Annals of the New York Academy of Sciences

authors： Schmidt M,Naumann H,Weidler C,Schellenberg M,Anders S,Straub RH

更新日期：2006-06-01 00:00:00

abstract：:In order to identify rate and stability of remission induced by low-dose prednisone comedication in early rheumatoid arthritis (RA), we evaluated patients with early RA (<1 year) who were randomized to receive (P) or not (non-P) low-dose prednisone in association with step-up disease-modifying antirheumatic drug thera...

journal_title：Annals of the New York Academy of Sciences

authors： Todoerti M,Scirè CA,Boffini N,Bugatti S,Montecucco C,Caporali R

更新日期：2010-04-01 00:00:00

abstract：:Adult musicians show superior neural sound discrimination when compared to nonmusicians. However, it is unclear whether these group differences reflect the effects of experience or preexisting neural enhancement in individuals who seek out musical training. Tracking how brain function matures over time in musically tr...

journal_title：Annals of the New York Academy of Sciences

authors： Putkinen V,Tervaniemi M,Saarikivi K,Huotilainen M

更新日期：2015-03-01 00:00:00

abstract：:Continuous infusion (CI) of coagulation factor concentrates has been used since the early 1990s. Recent reports of the occurrence of an inhibitor after CI have raised concerns about this method of treatment. We conducted a retrospective study to investigate the development of inhibitors after CI of Factor VIII concent...

journal_title：Annals of the New York Academy of Sciences

authors： von Auer Ch,Oldenburg J,von Depka M,Escuriola-Ettinghausen C,Kurnik K,Lenk H,Scharrer I

更新日期：2005-06-01 00:00:00

abstract：:Previous research on development of the Xenopus olfactory bulb from our laboratory has shown that mitral cells begin to differentiate after olfactory axons make contact with the olfactory bulb, and the number of olfactory axons is correlated with the number of mitral cells throughout development. In embryos, removal o...

journal_title：Annals of the New York Academy of Sciences

authors： Burd GD,Sein V

更新日期：1998-11-30 00:00:00

abstract：:To test a hypothesis about how otoliths resolve roll-tilts from translations, we measured human ocular torsion position [ocular counterrolling (OCR)] to maintained linear acceleration stimuli. All subjects (n = 8) were tested in two conditions where the same magnitude of shear along an interaural axis was generated in...

journal_title：Annals of the New York Academy of Sciences

authors： MacDougall HG,Curthoys IS,Betts GA,Burgess AM,Halmagyi GM

更新日期：1999-05-28 00:00:00

abstract：:A common feature across all animals, including humans, is that mitochondrial bioenergetics is linked to oxidative stress, but the nature of these relationships with survival is yet to be properly defined. In this study we included 12 Drosophila simulans isofemale lines: four of each distinct mtDNA haplogroup (siI, -II...

journal_title：Annals of the New York Academy of Sciences

authors： Ballard JW,Katewa SD,Melvin RG,Chan G

更新日期：2007-10-01 00:00:00

abstract：:Citizen soldiers (National Guard and Reserves) represent approximately 40% of the two million armed forces deployed to Afghanistan and Iraq. Twenty-five to forty percent of them develop PTSD, clinical depression, sleep disturbances, or suicidal thoughts. Upon returning home, many encounter additional stresses and hurd...

journal_title：Annals of the New York Academy of Sciences

authors： Greden JF,Valenstein M,Spinner J,Blow A,Gorman LA,Dalack GW,Marcus S,Kees M

更新日期：2010-10-01 00:00:00

abstract：:To examine whether treatment with cardiopulmonary bypass (CPB), which causes transient cellular immunity depression, influences tuberculin skin testing (TST) interpretation. The study was also aimed to assess the degree of cellular immunity depression following open heart surgery. Fifteen children from developing coun...

journal_title：Annals of the New York Academy of Sciences

authors： Stein M,Sela-Razon B,Linder I,Somekh E

更新日期：2007-08-01 00:00:00

abstract：:Cell transplantation therapy for diabetes and Parkinson's disease offers hope for long-term alleviation of symptoms. However, successful protocols remain elusive due to obstacles, including rejection and lack of tropic support for the graft. To enhance engraftment, testis-derived postmitotic Sertoli cells have been co...

journal_title：Annals of the New York Academy of Sciences

authors： Cameron DF,Hushen JJ,Nazian SJ,Willing A,Saporta S,Sanberg PR

更新日期：2001-11-01 00:00:00

abstract：:The aim of this study is to identify immune correlates of protection against tuberculosis induced by the current vaccine, Bacille Calmette Guerin (BCG). This knowledge should be valuable for developing and testing novel tuberculosis vaccines. Blood from 5675 10-week-old South African infants, routinely vaccinated with...

journal_title：Annals of the New York Academy of Sciences

authors： Hanekom WA

更新日期：2005-12-01 00:00:00

abstract：:The formation of bone is a continual process in vertebrate development, initiated during fetal development and persisting in adulthood in the form of remodeling and repair. The remarkable capacity of skeletal tissues to regenerate has led to the hypothesis that the molecular signaling pathways regulating skeletogenesi...

journal_title：Annals of the New York Academy of Sciences

authors： Ferguson CM,Miclau T,Hu D,Alpern E,Helms JA

更新日期：1998-10-23 00:00:00

abstract：:Rheumatoid arthritis (RA) is associated with accelerated atherosclerosis. Fractalkine, a CX3C/chemokine (CX3CL1), mediates monocytes-macrophage infiltration in activated endothelium, suggesting its specific role in atherosclerosis-related inflammation. In this study, we evaluate the following in early RA patients: the...

journal_title：Annals of the New York Academy of Sciences

authors： Pingiotti E,Cipriani P,Marrelli A,Liakouli V,Fratini S,Penco M,Giacomelli R

更新日期：2007-06-01 00:00:00

abstract：:Propofol is a widely used intravenous anesthetic agent. Our previous study showed that a therapeutic concentration of propofol can modulate macrophage functions. Mitochondria play critical roles in the maintenance of macrophage activities. This study attempted to evaluate further the effects of mitochondria on the pro...

journal_title：Annals of the New York Academy of Sciences

authors： Wu GJ,Tai YT,Chen TL,Lin LL,Ueng YF,Chen RM

更新日期：2005-05-01 00:00:00

abstract：:There are multiple lines of compelling evidence supporting the beneficial effect of exercise on the prevention and/or improvement of certain chronic diseases. However, exhaustive or intense exercise causes oxygen free radical generation and oxidative stress, which can lead to injuries and chronic fatigue as well as in...

journal_title：Annals of the New York Academy of Sciences

authors： Kim SY,Jun TW,Lee YS,Na HK,Surh YJ,Song W

更新日期：2009-08-01 00:00:00

abstract：:Previous studies in postmenopausal women have reported that estrogen treatment (ET) modulates the risk for developing Alzheimer's disease (AD). It has recently been hypothesized that there may be a "critical period" around the time of menopause during which the prescription of ET may reduce the risk of developing AD i...

journal_title：Annals of the New York Academy of Sciences

authors： Craig MC,Murphy DG

更新日期：2010-09-01 00:00:00

abstract：:Dopaminergic signaling in the brain is primarily modulated by dopamine transporters (DATs), which actively translocate extraneuronal dopamine back into dopaminergic neurons. Transporter proteins are highly dynamic, continuously trafficking between plasmalemmal and endosomal membranes. Changes in DAT membrane trafficki...

journal_title：Annals of the New York Academy of Sciences

authors： Schmitt KC,Reith ME

更新日期：2010-02-01 00:00:00

abstract：:This review focuses on the importance of bradykinin in myocardial preservation during ischemic arrest. Bradykinin is released from the heart spontaneously in response to ischemic stress, which may be viewed as a survival signal of the heart against ischemia. Bradykinin appears to function as a signaling molecule by co...

journal_title：Annals of the New York Academy of Sciences

authors： Sato M,Das DK,Engelman RM

更新日期：1999-06-30 00:00:00

abstract：:The rat displays three behaviors when surface and/or deep body temperatures rise above their normal levels: grooming, which spreads saliva over the fur to cool by evaporation; locomotion, which results in escape to a cooler environment; and relaxed postural extension, which reduces heat production by muscle activity a...

journal_title：Annals of the New York Academy of Sciences

authors： Roberts WW

更新日期：1988-01-01 00:00:00