Right ventricular end-systolic pressure-volume relation during propofol infusion.

Abstract:

:The effects of propofol on right ventricular function were studied in 11 ICU patients who needed sedation for acute respiratory failure or neurological diseases. Right ventricular function was studied using a thermodilution method at patients' bedside. Right ventricular ejection fraction (RVEF), cardiac output (CO), right ventricular end-diastolic volume (RVEDV), right ventricular end-systolic volume (RVESV), right ventricular end-systolic pressure (RVESP) and pulmonary capillary wedge pressure (PCWP) were obtained from a modified Swan-Ganz catheter. Calculation of right ventricular end-systolic pressure-volume relation (ESPVR) allowed to assess changes in right ventricular inotropic state. A baseline ESPVR was obtained before propofol infusion: RVESP = 0.21 RVESV + 2.4, r = 0.83, P < 0.0001. Then, patients were given an induction dose of 1 to 2.5 mg.kg-1 propofol over 1 min followed by a continuous infusion of 3 mg.kg-1.h-1. During propofol infusion heart rate, mean arterial pressure, PCWP, CO, systemic vascular resistance and RVEF significantly decreased. No change in RVEDV and RVESV was observed. ESPVR was significantly altered with a dramatic decrease in the slope of the relation: RVESP = 0.12 RVESV + 6.9 (P < 0.001 from baseline). Dobutamine was used in five patients with clinically significantly cardiac dysfunction and restored the slope of the ESPVR to the baseline value: RVESP = 0.22 RVESV + 6.3 (NS from baseline). In the study patients, propofol altered the inotropic state of the right ventricle.

authors

Martin C,Perrin G,Saux P,Papazian L,Albanese J,Gouin F

doi

10.1111/j.1399-6576.1994.tb03878.x

subject

Has Abstract

pub_date

1994-04-01 00:00:00

pages

223-8

issue

3

eissn

0001-5172

issn

1399-6576

journal_volume

38

pub_type

杂志文章
  • Tracheal intubation in patients with anticipated difficult airway using Boedeker intubation forceps and McGrath videolaryngoscope.

    abstract:BACKGROUND:Videolaryngoscopes with sharp angulated blades improve the view of the vocal cords but this does not necessarily result in higher success rates of intubation The aim of this study was to evaluate the efficacy of using Boedeker intubation forceps in conjunction with McGrath Series 5 Videolaryngoscope (MVL) in...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aas.12543

    authors: Strøm C,Barnung S,Kristensen MS,Bøttger M,Tvede MF,Rasmussen LS

    更新日期:2015-10-01 00:00:00

  • Hemodynamic effects of tracheal and intravenous adrenaline in infants with congenital heart anomalies.

    abstract:BACKGROUND:If intravenous access cannot be accomplished during cardiopulmonary resuscitation in children, tracheal administration of 100 micrograms/kg of adrenaline (ten times greater than the intravenous dose) is recommended. METHODS:In a randomized crossover study we recoreded the hemodynamic effect of a low dose of...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1399-6576.1996.tb04562.x

    authors: Jonmarker C,Olsson AK,Jögi P,Forsell C

    更新日期:1996-09-01 00:00:00

  • Rapid detection of oesophageal intubation: take care when using colorimetric capnometry.

    abstract:BACKGROUND:Rapid detection of a misplaced endotracheal tube in the esophagus is crucial, especially in emergency situations. Hence, we have compared the ability of a colorimetric CO2 indicator (Colibri technology, CO2ntrol 1) and a capnography to differentiate oesophageal and tracheal intubation, with and without CO2 a...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.1034/j.1399-6576.2002.460422.x

    authors: Puntervoll SA,Søreide E,Jacewicz W,Bjelland E

    更新日期:2002-04-01 00:00:00

  • The dumping valve and its clinical application.

    abstract::An open reservoir for the collection and evacuation of anaesthetic gases permits leakage to room air. The use of a closed reservior for the removal of overspill gas from anaesthetic circuits is described. Calibrated gas evacuation is carried out through an ejector flowmeter from the anesthetic circuit or from a closed...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.1976.tb05058.x

    authors: Jorgensen S,Thomsen A

    更新日期:1976-01-01 00:00:00

  • The use of a laryngeal mask airway in spontaneously breathing patients.

    abstract::The Laryngeal Mask Airway (LMA) is a new type of oropharyngeal airway that provides an alternative to endotracheal intubation and standard mask anaesthesia in certain cases. Once the patient is adequately anaesthetised, it can be inserted blindly, without recourse to laryngoscopy or muscle relaxants. Anaesthetists of ...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.1990.tb03170.x

    authors: Sarma VJ

    更新日期:1990-11-01 00:00:00

  • Effects of organic nitrate vasodilators on platelet function before and after cardiopulmonary bypass.

    abstract::Various in vitro, ex vivo and in vivo tests have shown that organic nitrates attenuate platelet function. Because organic nitrates are commonly administered to patients undergoing cardiac surgery, the postoperative bleeding tendency observed in these patients might be strengthened by nitrates. Therefore, we compared t...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1399-6576.1995.tb04137.x

    authors: Muikku O,Kuitunen A,Hynynen M

    更新日期:1995-07-01 00:00:00

  • Thiopental dose requirements for induction of anaesthesia and subsequent endotracheal intubation in patients with complete spinal cord injuries.

    abstract:BACKGROUND:Dose requirements of thiopental depend on patient characteristics and infusion rate. We determined thiopental dose requirements for induction of anaesthesia, and the effects of remifentanil on cardiovascular and bispectral index (BIS) responses to tracheal intubation in spinal cord-injured (SCI) patients und...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.2011.02640.x

    authors: Yoo KY,Jeong CW,Jeong HJ,Lee SH,Na JH,Kim SJ,Jeong ST,Lee J

    更新日期:2012-07-01 00:00:00

  • Serum NETosis expression and recurrence risk after regional or volatile anaesthesia during breast cancer surgery: A pilot, prospective, randomised single-blind clinical trial.

    abstract:BACKGROUND:Some experimental and retrospective clinical studies signal an association between certain anaesthetic techniques and tumour metastasis following breast cancer surgery. Neutrophil Extracellular Trapping (NETosis) is an immunological process, whereby neutrophils engulf tumour antigen then degranulate, leaving...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aas.13745

    authors: Aghamelu O,Buggy P,Smith G,Inzitari R,Wall T,Buggy DJ

    更新日期:2020-11-13 00:00:00

  • Hyperoxia and antioxidants during major non-cardiac surgery and risk of cardiovascular events: Protocol for a 2 × 2 factorial randomised clinical trial.

    abstract:BACKGROUND:Myocardial injury after non-cardiac surgery occurs in a high number of patients, resulting in increased mortality in the post-operative period. The use of high inspiratory oxygen concentrations may cause hyperoxia, which is associated with impairment of coronary blood flow. Furthermore, the surgical stress r...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aas.13518

    authors: Petersen C,Loft FC,Aasvang EK,Vester-Andersen M,Rasmussen LS,Wetterslev J,Jorgensen LN,Christensen R,Meyhoff CS

    更新日期:2020-03-01 00:00:00

  • Effect of intra-aortic magnesium on renal function during and after abdominal aortic surgery: a pilot study.

    abstract:BACKGROUND:Infrarenal aortic cross-clamping causes renal vasoconstriction. Magnesium may protect against renal deterioration through its vasodilatory properties. METHODS:Thirty patients with normal preoperative renal function undergoing infrarenal aortic cross-clamping for elective aortic surgery received magnesium (4...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1034/j.1399-6576.2000.00520.x

    authors: Bäcklund M,Pere P,Lepäntalo M,Lehtola A,Lindgren L

    更新日期:2000-05-01 00:00:00

  • Stroke following appendectomy under general anesthesia in a patient with basilar impression.

    abstract::We report a boy who developed a vertebral stroke immediately after an appendectomy. Basilar impression was diagnosed eight years after this event when skull roentgenograms revealed basilar impression with high standing tip of the odontoid. We speculate that muscle relaxation and cervical hyperextension during intubati...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1399-6576.2000.441015.x

    authors: Zotter H,Zenz W,Gallistl S,Zohrer B,Lindbichler F

    更新日期:2000-11-01 00:00:00

  • Sublingual buprenorphine for premedication and postoperative pain relief in orthopaedic surgery.

    abstract::The effect of sublingual buprenorphine (Temgesic) as a premedicant and for postoperative pain relief compared with morphine/pethidine was studied in 50 patients scheduled for elective surgery of the knee joint. Twenty-five patients received buprenorphine 0.4 mg sublingually 1 h before surgery and the same dose on dema...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.1985.tb02181.x

    authors: Risbo A,Chraemmer Jørgensen B,Kolby P,Pedersen J,Schmidt JF

    更新日期:1985-02-01 00:00:00

  • Unilateral recurrent laryngeal nerve neuropraxia following placement of a ProSeal laryngeal mask airway in a patient with CREST syndrome.

    abstract::We report a severe unilateral recurrent laryngeal nerve neuropraxia following use of the ProSeal laryngeal mask airway (PLMA) in a 71-year-old female patient with CREST syndrome. She required amputation of the 5th phalanx of foot because of gangrene due to Raynaud's syndrome. Anesthesia was induced with propofol, and ...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.2005.00616.x

    authors: Kawauchi Y,Nakazawa K,Ishibashi S,Kaneko Y,Ishikawa S,Makita K

    更新日期:2005-04-01 00:00:00

  • Comparison of the effect of ketamine added to bupivacaine and ropivacaine, on stress hormone levels and the duration of caudal analgesia.

    abstract:BACKGROUND:The aim of this study was to compare bupivacaine 0.25% and ropivacaine 0.2%, singly and in combination with ketamine, for caudal administration in children. Duration of analgesia, the need for other analgesics and the stress response were measured. METHODS:Eighty children were randomized into four groups of...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1399-6576.2005.00806.x

    authors: Akbas M,Titiz TA,Ertugrul F,Akbas H,Melikoglu M

    更新日期:2005-11-01 00:00:00

  • Postganglionic sympathetic nerve activity in halothane-anaesthetized rats during controlled and spontaneous ventilation.

    abstract::The aim of the study was to compare the effect of halothane anaesthesia on sympathetic nerve discharge in mechanically normoventilated and spontaneously breathing rats. Renal sympathetic nerve activity (rSNA), mean arterial pressure (MAP) and heart rate (HR) were measured in the conscious state and at the inspiratory ...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.1988.tb02757.x

    authors: Delle M,Thorén P,Sonander H,Majcherszyk S,Ricksten SE

    更新日期:1988-07-01 00:00:00

  • Fusion of dispatching centres into one entity: effects on performance.

    abstract:BACKGROUND:Dispatching centres were fused into one of the 112 entity, which caused concerns regarding whether the medical calls could be processed effectively also in the new centre. We evaluated the effects of the reform on key performance criteria in medical calls. METHODS:This observational study in the Helsinki Di...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.2010.02243.x

    authors: Määttä T,Kuisma M,Väyrynen T,Nousila-Wiik M,Porthan K,Boyd J,Kuosmanen J,Räsänen P

    更新日期:2010-07-01 00:00:00

  • The different responses of the hepatic arterial bed to hypovolaemia and to halothane anaesthesia.

    abstract::Ten dogs were subjected to a period of hypovolaemia (bleeding volume: 2% of body weight) and to a period of halothane anaesthesia (end-tidal halothane concentration: 1%). Mean arterial blood pressure decreased to 79% of control value during hypovolaemia and to 58% of control value during halothane anaesthesia. Mean to...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.1977.tb01247.x

    authors: Andreen M,Irestedt L,Zetterström B

    更新日期:1977-01-01 00:00:00

  • Studies on fluid extravasation related to induced hypothermia during cardiopulmonary bypass in piglets.

    abstract:BACKGROUND:Hypothermia, commonly used for organ protection during cardiopulmonary bypass (CPB), has been associated with changes in plasma volume, hemoconcentration and microvascular fluid shifts. Fluid pathophysiology secondary to hypothermia and the mechanisms behind these changes are still largely unknown. In a rece...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1399-6576.2001.045006720.x

    authors: Heltne JK,Koller ME,Lund T,Farstad M,Rynning SE,Bert JL,Husby P

    更新日期:2001-07-01 00:00:00

  • Mechanism of the ropivacaine-induced increase in intracellular Ca2+ concentration in rat aortic smooth muscle.

    abstract:BACKGROUND:Ropivacaine is a long-acting local anesthetic with low cardiac toxicity that induces vasoconstriction in vitro and in vivo. Vascular smooth muscle tone is regulated by changes in both intracellular Ca(2+) concentration ([Ca(2+)](i)) and myofilament Ca(2+) sensitivity. Therefore, the aim of this study was to ...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.2007.01390.x

    authors: Tokinaga Y,Ogawa K,Yu J,Kuriyama T,Minonishi T,Hatano Y

    更新日期:2007-10-01 00:00:00

  • Comparison of continuous epidural infusion of morphine/bupivacaine with fentanyl/bupivacaine for postoperative pain relief.

    abstract::The efficacy and safety of postoperative analgesia with continuous epidural infusion of either morphine or fentanyl in combination with bupivacaine were evaluated in 85 patients, ASA physical status I or II, undergoing thoracic and/or upper abdominal surgery. Patients were treated with one of the combinations for 48 h...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1399-6576.1994.tb03915.x

    authors: Saito Y,Uchida H,Kaneko M,Nakatani T,Kosaka Y

    更新日期:1994-05-01 00:00:00

  • Correction of pressure waveforms recorded by fluid-filled catheter recording systems: a new method using a transfer equation.

    abstract:BACKGROUND:Pressure measuring systems using fluid-filled catheters can result in the recording of distorted pressure waveforms. It results in phase delay, overestimation of systolic and, to a lesser extent, of diastolic pressure. We designed and evaluated a method to correct this pressure waveform distortion using an a...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.1998.tb05307.x

    authors: Lambermont B,Gerard P,Detry O,Kolh P,Potty P,D'orio V,Marcelle R

    更新日期:1998-07-01 00:00:00

  • Residents lack knowledge and practical skills in handling the difficult airway.

    abstract:BACKGROUND:Full-scale simulators have been developed in anaesthesia. We aimed at assessing Danish anaesthesia residents' knowledge and management of a standardized difficult airway situation in an advanced airway simulator. The reliability of the assessment was also determined. METHODS:Thirty-six residents answered a ...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.0001-5172.2004.00422.x

    authors: Rosenstock C,Østergaard D,Kristensen MS,Lippert A,Ruhnau B,Rasmussen LS

    更新日期:2004-09-01 00:00:00

  • Cardiovascular effects of desflurane and isoflurane in patients with coronary artery disease.

    abstract:BACKGROUND:Anaesthesia in patients with ischaemic heart disease may cause adverse haemodynamic reactions. This investigation compares the cardiovascular effects of equipotent concentrations of desflurane and isoflurane in 30 patients (ASA III) with coronary artery disease before surgical stimulation. METHODS:After sta...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1399-6576.1996.tb05571.x

    authors: Grundmann U,Müller M,Kleinschmidt S,Larsen B,Larsen R

    更新日期:1996-10-01 00:00:00

  • Continuous measurement of oxygen uptake. Evaluation of the Engström metabolic computer and clinical experiences.

    abstract::A new system for continuous measurement of oxygen uptake was tested. The tidal volumes delivered by the system, the accuracy of the oxygen sensor cell, measurement of the oxygen uptake at different inspired oxygen concentrations, and comparative tests of oxygen uptake using the Fick principle were studied. Judging fro...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.1987.tb02511.x

    authors: Behrendt W,Weiland C,Kalff J,Giani G

    更新日期:1987-01-01 00:00:00

  • A novel risk score for severe ARDS patients undergoing ECMO after retrieval from peripheral hospitals.

    abstract:BACKGROUND:Extracorporeal Membrane Oxygenation in severe ARDS unresponsive to conventional protective ventilation is associated with elevated costs, resource and complications, and appropriate risk stratification of candidate patients could be useful to recognize those more likely to benefit from ECMO. We aimed to deri...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aas.13022

    authors: Lazzeri C,Cianchi G,Mauri T,Pesenti A,Bonizzoli M,Batacchi S,Chiostri M,Socci F,Peris A

    更新日期:2018-01-01 00:00:00

  • Catheter-related epidural abscesses -- don't wait for neurological deficits.

    abstract::Epidural abscess is a rare but serious complication of epidural anesthesia for peri- and postoperative analgesia. It is feared because of possible persistent neurological deficits. Epidural abscess presents mostly with a classic triad of symptoms: back pain, fever and variable neurological signs and symptoms. When neu...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1399-6576.2002.460523.x

    authors: Royakkers AA,Willigers H,van der Ven AJ,Wilmink J,Durieux M,van Kleef M

    更新日期:2002-05-01 00:00:00

  • Sleep disturbances in critically ill patients in ICU: how much do we know?

    abstract::Sleep disturbances in the intensive care unit (ICU) seem to lead to development of delirium, prolonged ICU stay, and increased mortality. That is why sufficient sleep is important for good outcome and recovery in critically ill patients. A variety of small studies reveal pathological sleep patterns in critically ill p...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/j.1399-6576.2012.02672.x

    authors: Boyko Y,Ording H,Jennum P

    更新日期:2012-09-01 00:00:00

  • Vancomycin levels are frequently subtherapeutic in critically ill patients: a prospective observational study.

    abstract:BACKGROUND:Appropriate utilization of vancomycin is important to attain therapeutic targets while avoiding clinical failure and the development of antimicrobial resistance. Our aim was to observe the use of vancomycin in an intensive care population, with the main focus on achievement of therapeutic serum concentration...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aas.12897

    authors: Bakke V,Sporsem H,Von der Lippe E,Nordøy I,Lao Y,Nyrerød HC,Sandvik L,Hårvig KR,Bugge JF,Helset E

    更新日期:2017-07-01 00:00:00

  • The influence of nitrous oxide on recovery of bowel function after abdominal hysterectomy.

    abstract::The influence of nitrous oxide on the recovery of bowel function was studied in 36 patients anaesthetised for elective abdominal hysterectomy with or without salpingo-oophorectomy. Patients were randomly assigned to receive either isoflurane in nitrous oxide and 30% oxygen (N2O group) or isoflurane in air and 30% oxyg...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1399-6576.1993.tb03791.x

    authors: Pedersen FM,Wilken-Jensen C,Knudsen F,Lindekaer AL,Svare EI

    更新日期:1993-10-01 00:00:00

  • Implementation of a trauma system in Norway: a national survey.

    abstract:BACKGROUND:Trauma systems have improved outcomes for injured patients, but might be challenging to implement. We assessed the implementation of a trauma system in Norway after recommendations for a national trauma system were published in 2007, with a focus on elements in acute care hospitals. METHODS:All hospitals in...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aas.12467

    authors: Dehli T,Gaarder T,Christensen BJ,Vinjevoll OP,Wisborg T

    更新日期:2015-03-01 00:00:00