Role of GABA and glutamate circuitry in hypothalamo-pituitary-adrenocortical stress integration.

abstract：:Experimental Herpesvirus hominis encephalitis in 3-week-old Swiss mice was utilized to evaluate the antiviral effects of adenine arabinoside (ara-A), phosphonacetic acid (PAA), and humoral antibodies to H. hominis (HIG). Administration of ara-A, PAA, or HIG during the early phase of infection reduced the mortality rat...

journal_title：Annals of the New York Academy of Sciences

authors： Cho CT,Feng KK

更新日期：1977-03-04 00:00:00

abstract：:Insulin-like factor 3 (INSL3), previously known as the relaxin-like factor (RLF), is a major peptide hormone secreted from the testicular Leydig cells of adult men and circulating in the blood at a concentration of approximately 1 ng/mL. Women also produce INSL3 in the theca interna cells of ovarian follicles, but cir...

journal_title：Annals of the New York Academy of Sciences

authors： Ivell R,Hartung S,Anand-Ivell R

更新日期：2005-05-01 00:00:00

abstract：:Corn flour and maize meal fortification can benefit the consumer when the added nutrient contents are in amounts appropriate to address nutrient gaps. Legislative instruments (standards and regulations) are needed to provide guidance to the producers and food control authorities. We reviewed a number of national stand...

journal_title：Annals of the New York Academy of Sciences

authors： Makhumula P,Dary O,Guamuch M,Tom C,Afidra R,Rambeloson Z

更新日期：2014-04-01 00:00:00

abstract：:Because of the sedative/hypnotic and euphoric effects of gamma-hydroxybutyric acid (GHB), the recreational use of the drug has increased significantly. In the current study we investigated the sedative and rewarding effects of GHB in Swiss Webster mice. Although the acute administration of GHB (200 mg/kg) caused marke...

journal_title：Annals of the New York Academy of Sciences

authors： Itzhak Y,Ali SF

更新日期：2002-06-01 00:00:00

abstract：:To summarize (Fig. 10), the structural consequences of monocular deprivation include the following changes: the relay cells in the binocular segments of the deprived geniculate layers shrink and contain less of the possible neurotransmitter NAAG. These changes appear to be secondary to a loss of terminal synaptic arbo...

journal_title：Annals of the New York Academy of Sciences

authors： Tieman SB

更新日期：1991-01-01 00:00:00

abstract：:The aim of this study was to investigate the influence of long-lasting, extensive rowing training on body fluids in 12 experienced rowers (23.3 +/- 6.3 years, 188.7 +/- 5.9 cm, 82.0 +/- 10.8 kg, body mass index [BMI] 23.7 +/- 2.1). All rowers had a light traditional breakfast about 3 h before the training. The subject...

journal_title：Annals of the New York Academy of Sciences

authors： Jürimäe J,Jürimäe T,Pihl E

更新日期：2000-05-01 00:00:00

abstract：:N-type calcium channels both generate the initial calcium signal to trigger neurotransmitter release and also interact with synaptic release proteins at many mammalian central nervous system synapses. Two isoforms of the alpha 1B N-type channel from rat brain (alpha 1B-I and alpha 1B-II) were found to differ in four r...

journal_title：Annals of the New York Academy of Sciences

authors： Stea A,Dubel SJ,Snutch TP

更新日期：1999-04-30 00:00:00

abstract：:The importance of prognostic factors in predicting outcome in pediatric oncology is largely recognized, and most current protocols tailor treatment based on risk stratification. Further refinements of classical staging systems are ongoing, and the future of pediatric oncology is in the development of strategies based ...

journal_title：Annals of the New York Academy of Sciences

authors： Yanagisawa T,Bartels U,Bouffet E

更新日期：2008-09-01 00:00:00

abstract：:Megadose haploidentical transplants, mismatched at three HLA loci, engraft rapidly and durably without induction of graft-versus-host disease (GVHD). In vitro studies suggest that veto cells, contained in the population of hematopoietic progenitors, facilitate this favorable outcome. Cytotoxic T cells, not reactive ag...

journal_title：Annals of the New York Academy of Sciences

authors： Reisner Y

更新日期：2001-06-01 00:00:00

abstract：:Adult musicians show superior neural sound discrimination when compared to nonmusicians. However, it is unclear whether these group differences reflect the effects of experience or preexisting neural enhancement in individuals who seek out musical training. Tracking how brain function matures over time in musically tr...

journal_title：Annals of the New York Academy of Sciences

authors： Putkinen V,Tervaniemi M,Saarikivi K,Huotilainen M

更新日期：2015-03-01 00:00:00

abstract：:Three vaccine stabilates of Theileria parva, of which sporozoites are being used against East Coast fever, were characterized by immunological and molecular biology techniques before being used for a national vaccination campaign in Kenya. T. parva Marikebuni stabilates 316 and 3014, and T. parva Lanet were used in th...

journal_title：Annals of the New York Academy of Sciences

authors： Sparagano OA,Zanaa O,Ambrose N

更新日期：1998-06-29 00:00:00

abstract：:Evolutionary theories suggest that the expression of extended longevity depends on the organism's ability to shift energy from reproduction to somatic maintenance. New data led us to reexamine our older data and integrate the two into a larger picture of the genetic and metabolic alterations required if the animal is ...

journal_title：Annals of the New York Academy of Sciences

authors： Arking R,Buck S,Hwangbo DS,Lane M

更新日期：2002-04-01 00:00:00

abstract：:Cytotoxic T lymphocytes (CTL) play a central role in successful control of HIV. Induction of effective CTL responses may therefore be an essential requirement of HIV vaccines. Knowledge of CTL epitopes targeted either in natural infection or following vaccination will be critical to understanding the anti-HIV immune r...

journal_title：Annals of the New York Academy of Sciences

authors： Goulder PJ

更新日期：2000-11-01 00:00:00

abstract：:In the pituitary of mammals, the GnRH receptor (GnRHR) plays crucial roles in the neuroendocrine control of reproductive function. This receptor is specifically expressed by the gonadotrope cells scattered among the five other endocrine cell types constituting the anterior pituitary; it is also expressed in other orga...

journal_title：Annals of the New York Academy of Sciences

authors： Schang AL,Counis R,Magre S,Bleux C,Granger A,Ngô-Muller V,Chenut MC,Ishaq M,Cohen-Tannoudji J,Laverrière JN

更新日期：2011-03-01 00:00:00

abstract：:Eight children with congenital adrenal hyperplasia and late initiation of corticosteroid treatment are included in the present study. Four of them received LHRHa treatment for the arrest of central precocious puberty, while the other four served as controls. The administration of LHRHa was effective in arresting the m...

journal_title：Annals of the New York Academy of Sciences

authors： Dacou-Voutetakis C,Karidis N

更新日期：1993-05-28 00:00:00

abstract：:Our objective was to learn the prevalence of spotted fever group (SFG) Rickettsia detected in ticks in La Rioja, in the north of Spain. From 2001 to 2005, 496 ticks representing 7 tick species were analysed at the Hospital de La Rioja. Ticks were removed from humans with or without rickettsial syndrome (n = 59) or col...

journal_title：Annals of the New York Academy of Sciences

authors： Oteo JA,Portillo A,Santibáñez S,Pérez-Martínez L,Blanco JR,Jiménez S,Ibarra V,Pérez-Palacios A,Sanz M

更新日期：2006-10-01 00:00:00

abstract：:The presented paper describes a multi-disciplinary cooling selection approach applied to major gas turbine engine hot section components, including turbine nozzles, blades, discs, combustors and support structures, which maintain blade tip clearances. The paper demonstrates benefits of close interaction between partic...

journal_title：Annals of the New York Academy of Sciences

authors： Glezer B

更新日期：2001-05-01 00:00:00

abstract：:The proto-oncogene c-myc is involved in multiple cell pathways with opposite effects on cell outcome of death or proliferation. It has been proposed that these different roles depend on the sequestration of c-Myc protein in cellular compartments and/or its phosphorylation. We speculated that subcellular localization o...

journal_title：Annals of the New York Academy of Sciences

authors： Supino R,Favini E,Cuccuru G,Zunino F,Scovassi AI

更新日期：2007-01-01 00:00:00

abstract：:Research in the area of adolescent alcohol use is progressing rapidly, as exemplified by the chapters in this section. Basic animal research in rodents has revealed adolescents to be more sensitive than adults to ethanol-induced disruptions in brain plasticity, although adolescents conversely are relatively insensitiv...

journal_title：Annals of the New York Academy of Sciences

authors： Spear LP

更新日期：2004-06-01 00:00:00

abstract：:The identification of high-affinity ligands for PPAR gamma has revealed the role of this receptor as the molecular target for the antidiabetic activity of the thiazolidinediones. The surprising observation that agonists of an adipogenic transcription factor reverse the obesity-associated disease of diabetes highlights...

journal_title：Annals of the New York Academy of Sciences

authors： Willson TM,Lehmann JM,Kliewer SA

更新日期：1996-12-27 00:00:00

abstract：:There is a significant increase in the percentage and absolute number of activated lymphocytes (OKT10+, IL2R1+) after ECT treatment of major depressive disorder. There is an acute decrease in the absolute number of total lymphocytes, T8+ and Leu11+ cells one hour after a single ECT. ...

journal_title：Annals of the New York Academy of Sciences

authors： Fischler B,Bocken R,Schneider I,De Waele M,Thielemans K,Derde MP

更新日期：1992-04-15 00:00:00

abstract：:This review will focus on the free radical signaling mechanism of preconditioning. The results from our laboratory as well as studies from other laboratories suggest that reactive oxygen species function as second messenger during myocardial adaptation to ischemia. This review provides evidence for the first time that...

journal_title：Annals of the New York Academy of Sciences

authors： Das DK,Engelman RM,Maulik N

更新日期：1999-06-30 00:00:00

abstract：:Athletic women are at risk for developing ovulatory dysfunction, which presents variably as menstrual irregularity or absence. Initially characterized as an isolated disruption of hypothalamic gonadotropin-releasing hormone (GnRH) release, athletic amenorrhea, a form of hypogonadotropic hypogonadism, is invariably acc...

journal_title：Annals of the New York Academy of Sciences

authors： Pauli SA,Berga SL

更新日期：2010-09-01 00:00:00

abstract：:The smooth muscle myosin heavy chain (MHC) gene and its isoforms are excellent molecular markers that reflect smooth muscle phenotypes. The SMemb/Nonmuscle Myosin Heavy Chain B (NMHC-B) is a distinct MHC gene expressed predominantly in phenotypically modulated SMCs (synthetic-type SMC). To dissect the molecular mechan...

journal_title：Annals of the New York Academy of Sciences

authors： Nagai R,Suzuki T,Aizawa K,Miyamoto S,Amaki T,Kawai-Kowase K,Sekiguchi KI,Kurabayashi M

更新日期：2001-12-01 00:00:00

abstract：:Most chemical contaminants occur in highest concentrations in coastal waters, often maximized in very localized areas. In general, this situation represents the exposure pattern for marine animals. However, the availability of contaminant to an organism depends not only on its concentration but also on its chemical na...

journal_title：Annals of the New York Academy of Sciences

authors： Whittle KJ,Hardy R,Holden AV,Johnston R,Pentreath RJ

更新日期：1978-09-29 00:00:00

abstract：:In order to analyze neuronal computations in the first olfactory processing center, the olfactory bulb, we measured odor-evoked activity patterns across large numbers of neurons within the intact olfactory bulb of zebrafish using optical and electrophysiological methods. We found that the olfactory bulb performs multi...

journal_title：Annals of the New York Academy of Sciences

authors： Friedrich RW,Yaksi E,Judkewitz B,Wiechert MT

更新日期：2009-07-01 00:00:00

abstract：:Tight junctions (TJs) regulate paracellular barriers and claudins (Cld) form the backbone of TJ strands. To elucidate the molecular mechanism of claudin polymer formation, TJs were reconstituted by claudin transfection of TJ-free HEK293 cells. Therewith, typical TJ stands can be found at cell-cell contacts. In additio...

journal_title：Annals of the New York Academy of Sciences

authors： Rossa J,Lorenz D,Ringling M,Veshnyakova A,Piontek J

更新日期：2012-06-01 00:00:00

abstract：:Sacrocaudal afferent (SCA) stimulation is used in this work to study neural pathways involved in sensory-activation of central pattern generators (CPGs) in the isolated spinal cord of the neonatal rat. Surgical manipulations of the white matter funiculi and confocal imaging of back-labeled funicular pathways suggest t...

journal_title：Annals of the New York Academy of Sciences

authors： Lev-Tov A,Etlin A,Blivis D

更新日期：2010-06-01 00:00:00

abstract：:Mounting evidence indicates increased susceptibility to cell death and increased oxidative damage as common features in neurons from sporadic Alzheimer's disease (AD) patients but also from familial AD (FAD) cases. Autosomal dominant forms of FAD are caused by mutations of the amyloid precursor protein (APP) gene and ...

journal_title：Annals of the New York Academy of Sciences

authors： Eckert A,Marques CA,Keil U,Schüssel K,Müller WE

更新日期：2003-12-01 00:00:00

abstract：:The glucocorticoid receptor (GR) is crucial for the effects of glucocorticoids (GCs). Several polymorphisms of the GR are associated with altered sensitivity to GCs. For the ER22/23EK polymorphism, a relative GC resistance has been demonstrated. In vivo, this was suggested by a smaller response to a dexamethasone supp...

journal_title：Annals of the New York Academy of Sciences

authors： Manenschijn L,van den Akker EL,Lamberts SW,van Rossum EF

更新日期：2009-10-01 00:00:00