Abstract:
:Meiotic pairing has now been shown to require heterochromatic homology and to be sensitive to repeat number in both male and female Drosophila. The increased pairing ability of repetitive sequences could be one reason that most eukaryotes allow the accumulation of tandem repeated elements. This may well be a reflection of a general role for heterochromatin, and at least a partial explanation of the ubiquity of heterochromatin through the eukaryotes.
journal_name
Chromosomajournal_title
Chromosomaauthors
Irick Hdoi
10.1007/BF00364720subject
Has Abstractpub_date
1994-03-01 00:00:00pages
1-3issue
1eissn
0009-5915issn
1432-0886journal_volume
103pub_type
杂志文章,评审相关文献
CHROMOSOMA文献大全abstract::We determined the structure of the Schizosaccharomyces pombe centromere cen3 using direct genomic mapping and cosmid walking. The repetitive region of cen3 is approximately 110 kb, much longer than that of the previously determined cen1 and cen2 regions. The approximately 30 kb long left and approximately 60 kb right ...
journal_title:Chromosoma
pub_type: 杂志文章
doi:10.1007/BF00365153
更新日期:1991-12-01 00:00:00
abstract::Telomeric DNA is present at the ends of eukaryotic chromosomes and is bound by telomere "capping" proteins, which are the (Cdc13-Stn1-Ten1) CST complex, Ku (Yku70-Yku80), and Rap1-Rif1-Rif2 in budding yeast. Inactivation of any of these complexes causes telomere "uncapping," stimulating a DNA damage response (DDR) tha...
journal_title:Chromosoma
pub_type: 杂志文章,评审
doi:10.1007/s00412-011-0357-2
更新日期:2012-04-01 00:00:00
abstract::Macrosatellites are large polymorphic tandem arrays. The human subtelomeric macrosatellite D4Z4 has 11-150 repeats, each containing a copy of the intronless DUX4 gene. DUX4 is linked to facioscapulohumeral muscular dystrophy, but its normal function is unknown. The DUX gene family includes DUX4, the intronless Dux mac...
journal_title:Chromosoma
pub_type: 杂志文章
doi:10.1007/s00412-012-0380-y
更新日期:2012-10-01 00:00:00
abstract::We show that methylated lysine 9 of histone H3 (Me9H3) is a marker of heterochromatin in divergent animal species. It localises to both constitutive and facultative heterochromatin and replicates late in S-phase of the cell cycle. Significantly, Me9H3 is enriched in the inactive mammalian X chromosome (Xi) in female c...
journal_title:Chromosoma
pub_type: 杂志文章
doi:10.1007/s00412-002-0182-8
更新日期:2002-03-01 00:00:00
abstract::The heterochromatin of chromosomes 2 and 3 of Drosophila melanogaster contains about 30 essential genes defined by genetic analysis. In the last decade only a few of these genes have been molecularly characterized and found to correspond to protein-coding genes involved in important cellular functions. Moreover, sever...
journal_title:Chromosoma
pub_type: 杂志文章
doi:10.1007/s00412-003-0241-9
更新日期:2003-07-01 00:00:00
abstract::One of the subjects within the meiotic field that has been actively investigated in the recent years is the temporal and functional relationships between meiotic recombination, cohesin loading and synaptonemal complex (SC) assembly. Although the study of meiotic mutants has shed some light, many questions remain to be...
journal_title:Chromosoma
pub_type: 杂志文章
doi:10.1007/s00412-009-0204-x
更新日期:2009-06-01 00:00:00
abstract::The method of ultrathin sections of unsquashed salivary gland polytene chromosomes of Ch. thummi was applied to their ultrastrual mapping. There was a good agreement between electron micrographs and Hägele's light microscopic map (1970) with respect to the pattern and number of bands. 94% of bands were identified in l...
journal_title:Chromosoma
pub_type: 杂志文章
doi:10.1007/BF00288332
更新日期:1976-03-31 00:00:00
abstract::Mitomycin C-induced sister chromatic exchange and quadriradial formation were studied in chromosomes from Muntiacus muntjac fibroblasts and A9, a transformed mouse cell line. We present the first direct cytological evidence for the induction of true somatic recombination involving homologous chromosomes. Analysis of t...
journal_title:Chromosoma
pub_type: 杂志文章
doi:10.1007/BF00293724
更新日期:1976-06-30 00:00:00
abstract::By means of a cytological technique involving 5-bromodeoxyuridine, acridine orange, and fluorescence microscopy, the asynchronously replicating, hence genetically inactivated, X chromosome was identified in 6- to 8-day embryos from female mice heterozygous for Searle's translocation T(X;16)16H (abbreviated as T16H) ma...
journal_title:Chromosoma
pub_type: 杂志文章
doi:10.1007/BF00368155
更新日期:1980-01-01 00:00:00
abstract::The frequency and distribution of chiasmata and the nature of terminal "associations" was re-examined in Syrian hamster spermatocytes using the 5-bromo-2'-deoxyuridine (BrdU) antibody technique (BAT) for differential chromatid labelling. Differential chromatid substitution was achieved by BrdU incorporation at the pen...
journal_title:Chromosoma
pub_type: 杂志文章
doi:10.1007/BF01731702
更新日期:1990-08-01 00:00:00
abstract::Centromere protein B (CENP-B) is a centromeric DNA-binding protein that binds to alpha-satellite DNA at the 17 bp CENP-B box sequence. The binding of CENP-B, along with other proteins, to alpha-satellite DNA sequences at the centromere, is thought to package the DNA into heterochromatin subjacent to the kinetochore of...
journal_title:Chromosoma
pub_type: 杂志文章
doi:10.1007/s004120050343
更新日期:1998-12-01 00:00:00
abstract::The overall nuclease sensitivity and methylation of active and inactive X chromosomes of kangaroos were examined by in situ nick translation. Cultured fibroblasts of subspecies wallaroo-euro (Macropus robustus robustus; Macropus robustus erubescens) hybrids were used, enabling the paternally and maternally derived X c...
journal_title:Chromosoma
pub_type: 杂志文章
doi:10.1007/BF00356024
更新日期:1993-01-01 00:00:00
abstract::BrdU-substituted Chinese hamster chromosomes were treated with a hog Na2HPO4 solution and stained with Giemsa to produce sister chromatid differential staining (SCD). The process of SCD was examined with the Nomarski differential interference microscope and the scanning electron microscope. After the Na2HPO4 treatment...
journal_title:Chromosoma
pub_type: 杂志文章
doi:10.1007/BF00285754
更新日期:1981-01-01 00:00:00
abstract::Recent progress in elucidating the function of synaptonemal complex (SC) proteins and of cohesins in meiocytes made possible, in particular, through the analysis of mice deficient in SC or cohesin proteins has significantly enriched our understanding of how meiotic chromosome architecture is determined. Cohesins and t...
journal_title:Chromosoma
pub_type: 杂志文章,评审
doi:10.1007/s00412-006-0060-x
更新日期:2006-06-01 00:00:00
abstract::We provide evidence that centromere-specific 155 bp DNA repeats terminate one pair of telomeres at the telocentric, left end of the short fourth chromosome in Chironomus pallidivittatus. Earlier evidence indicated that all other telomeres are terminated by 340 bp telomere-specific repeats. DNA that borders the 155 bp ...
journal_title:Chromosoma
pub_type: 杂志文章
doi:10.1007/s00412-001-0176-y
更新日期:2002-02-01 00:00:00
abstract::The XY bivalent contained within the sex vesicle of chromosomally normal male mice shows virtually no RNA transcriptional activity as measured by autoradiography during the prophase of meiosis. Tertiary trisomic males, derived from the T 70 H and T 31 H reciprocal translocations, include the extra small marker chromos...
journal_title:Chromosoma
pub_type: 杂志文章
doi:10.1007/BF00292748
更新日期:1986-01-01 00:00:00
abstract::Previous studies of the Robertsonian polymorphism in the Atlantic dog-whelk, Nucella lapillus (2n = 26-36), have been limited by the inability to identify unequivocally individual chromosomes in the karyotype. This species, as with many other marine invertebrates, has proven largely refractory to the standard (mammali...
journal_title:Chromosoma
pub_type: 杂志文章
doi:10.1007/BF00352269
更新日期:1996-03-01 00:00:00
abstract::DNA reassociation kinetics were studied, by means of the hydroxyapatite chromatography method, for four species of Amphibians with different nuclear DNA content: Xenopus laevis (3 pg DNA per haploid genome) and Bufo bufo (7 pg) of the Anura subclass and Triturus cristatus (23 pg) and Necturus maculosus (52 pg) of the ...
journal_title:Chromosoma
pub_type: 杂志文章
doi:10.1007/BF00327706
更新日期:1976-12-06 00:00:00
abstract::Genomic sequencing reveals similar but limited numbers of protein-coding genes in different genomes, which begs the question of how organismal diversities are generated. Alternative pre-mRNA splicing, a widespread phenomenon in higher eukaryotic genomes, is thought to provide a mechanism to increase the complexity of ...
journal_title:Chromosoma
pub_type: 杂志文章,评审
doi:10.1007/s00412-013-0407-z
更新日期:2013-06-01 00:00:00
abstract::We report on the construction of the first comparative Zoo-FISH map of a marine mammal. Zoo-FISH with DNA probes from a human chromosome-specific library to metaphase spreads of the harbor seal (Phoca vitulina) disclosed 31 conserved syntenic segments covering the complete autosomal complement and the X chromosome. Co...
journal_title:Chromosoma
pub_type: 杂志文章
doi:10.1007/s004120050230
更新日期:1997-07-01 00:00:00
abstract::Mammalian heterochromatin proteins 1 (HP1alpha, HP1beta, and HP1gamma) are nonhistone proteins that interact in vitro with a set of proteins that play a role in chromatin silencing, transcription, and chromatin remodeling. Using antibodies specific for each HP1 isoform, we showed that they segregate in distinct nuclea...
journal_title:Chromosoma
pub_type: 杂志文章
doi:10.1007/s004120050372
更新日期:1999-08-01 00:00:00
abstract::In order to induce chromosomal rearrangements, males were exposed to x-rays and then mated to non-irradiated females. The number of each type of structural alteration was determined by examination of the polytene chromosomes of the F1 progeny. -- A comparison of the results with similar studies made on Drosophila reve...
journal_title:Chromosoma
pub_type: 杂志文章
doi:10.1007/BF00329175
更新日期:1975-12-10 00:00:00
abstract::Three new 18S.26S rRNA gene loci were identified in common wheat by sequential N-banding and in situ hybridization (ISH) analysis. Locus Nor-A7 is located at the terminal area of the long arm of 5A in both diploid and polyploid wheats. Locus Nor-B6 is located in N-band 1BL2.5 of the long arm of chromosome 1B in Tritic...
journal_title:Chromosoma
pub_type: 杂志文章
doi:10.1007/BF00368010
更新日期:1994-06-01 00:00:00
abstract::Aedes aegypti spermatocytes were reconstructed from electron micrographs. The species has tight somatic pairing of the chromosomes, and there are therefore no classical leptotene and zygotene stages, but rather a gradual transition from somatic pairing to meiotic pairing (= pachytene). The term "prepachytene" has been...
journal_title:Chromosoma
pub_type: 杂志文章
doi:10.1007/BF00329808
更新日期:1985-01-01 00:00:00
abstract::Short DNA regions, known to contain replication origins, were isolated from 2 M NaCl resistant nuclear structures of Physarum polycephalum after predigestion with DNase. Regions of 100 bp average length were cloned and sequenced. About 25% of the clones contained direct repeats of 12 to 16 bp and variable base sequenc...
journal_title:Chromosoma
pub_type: 杂志文章
doi:10.1007/BF00292787
更新日期:1989-12-01 00:00:00
abstract::Osteosarcoma (OS) is characterized by chromosomal instability and high copy number gene amplification. The breakage-fusion-bridge (BFB) cycle is a well-established mechanism of genome instability in tumors and in vitro models used to study the origins of complex chromosomal rearrangements and cancer genome amplificati...
journal_title:Chromosoma
pub_type: 杂志文章
doi:10.1007/s00412-006-0074-4
更新日期:2006-12-01 00:00:00
abstract::By taking advantage of the fact that fluorescent light (FL) induces strand breaks only in bromodeoxyuridine(BrdUy-substituted DNA, and that those breaks eventually lead to the formation of sister chromatid exchanges (SCEs), the response of SCEs to FL was studied carefully in Chinese hamster chromosomes in which, out o...
journal_title:Chromosoma
pub_type: 杂志文章
doi:10.1007/BF00292776
更新日期:1977-02-03 00:00:00
abstract::The distribution of constitutive heterochromatin has been investigated in four chromosomal races of the grasshopper Caledia captiva (2n=23 male/24 female) by the C-banding technique. Each of the four races was found to have a distinctive banding pattern which is associated with the inter-racial differences in chromoso...
journal_title:Chromosoma
pub_type: 杂志文章
doi:10.1007/BF00293114
更新日期:1976-06-30 00:00:00
abstract::Many different chromosomal races with reduced chromosome number due to the presence of Robertsonian fusion metacentrics have been described in western Europe and northern Africa, within the distribution area of the western house mouse Mus musculus domesticus. This subspecies of house mouse has become the ideal model f...
journal_title:Chromosoma
pub_type: 历史文章,杂志文章,评审
doi:10.1007/s00412-014-0477-6
更新日期:2014-12-01 00:00:00
abstract::The molecular structure of chromatin during dogfish spermiogenesis was examined by electron microscopy after the dispersion of nuclei at low ionic strength. In early and late stages of differentiation (round and elongating spermatids), chromatin is globular, although basic nuclear proteins are different from those pre...
journal_title:Chromosoma
pub_type: 杂志文章
doi:10.1007/BF00292041
更新日期:1980-01-01 00:00:00