Are the configuration and neck morphology of experimental aneurysms predictable? A technical approach.


:Aneurysm configuration and neck morphology are important factors in the decision for cerebral aneurysm therapy, i.e., clipping versus coiling. The aim of our study was to create various aneurysm configurations in a predictable and reproducible way in an animal model. In our recently proposed endovascular approach to produce bifurcation aneurysms in the rabbit, the right common carotid artery (CCA) is surgically exposed and distally ligated, and a sheath is advanced retrogradely into the CCA, the base of which is proximally occluded using a Fogarty balloon. Subsequently, elastase is injected via a microcatheter that is placed directly distal to the balloon and allowed to incubate for 20 min. After removal of the sheath, saccular aneurysms begin to form within 2 weeks. For greater variability in aneurysm size and neck morphology, we modified two parameters of this formerly established elastase-induced aneurysm model--the distance between the balloon and sheath and the level of balloon position--before the elastase was endoluminally incubated in 15 rabbits. Three weeks after aneurysm induction, the size and configuration of the aneurysms were controlled using DSA. Our results confirm that balloon occlusion in the brachiocephalic trunk results in broad-based aneurysms, whereas balloon occlusion in the CCA gives rise to circumscribed aneurysm necks. By increasing the distance between the balloon and sheath, the rabbits developed significantly larger aneurysms. The balloon-sheath distance and the level of balloon occlusion proved to be parameters whose modifications result in predictable and reproducible aneurysm variants that can be used for the testing of endovascular devices.






Thiex R,Möller-Hartmann W,Hans FJ,Scherer K,Krings T




Has Abstract


2004-07-01 00:00:00












  • Contrast enhancement of cerebral infarcts. Incidence and clinical value in different states of cerebral infarction.

    abstract::Information obtained from CT scan after contrast administration was evaluated in 59 consecutive stroke patients. CT scans before and after contrast administration were performed 3 days and 2 1/2 weeks after stroke. A plain CT scan was repeated 6 months later. Contrast enhancement was practically not seen on the first ...


    pub_type: 杂志文章


    authors: Skriver EB,Olsen TS

    更新日期:1982-01-01 00:00:00

  • Differentiation of recent and old cerebral infarcts by diffusion-weighted MRI.

    abstract::We performed MRI, including diffusion-weighted imaging, in 15 patients with recurrent strokes with acute ischaemia and at least one old lesion according to the clinical history and/or CT. Routine MRI showed similar signal intensity changes in both situations. Diffusion-weighted images, however, were positive in all ac...


    pub_type: 杂志文章


    authors: Fitzek C,Tintera J,Müller-Forell W,Urban P,Thömke F,Fitzek S,Hopf HC,Stoeter P

    更新日期:1998-12-01 00:00:00

  • Neuroimaging in lissencephaly type I.

    abstract::The CT scan's of 22 patients with lissencephaly type I, a severe developmental disorder of the cerebral cortex, were studied. In 6 patients a magnetic resonance (MR), scan was also performed. The CT and MR scans of the lissencephaly patients were compared to a control group consisting of 49 patients with a normal CT o...


    pub_type: 杂志文章


    authors: de Rijk-van Andel JF,van der Knaap MS,Valk J,Arts WF

    更新日期:1991-01-01 00:00:00

  • Cerebral abscesses: investigation using apparent diffusion coefficient maps.

    abstract::The combination of high signal and reduced apparent diffusion coefficients (ADC) within abscesses on diffusion-weighted MRI (DWI) has been reported as characteristic of abscesses, and useful for distinguishing them from cystic or necrotic neoplasms. To assess whether these are consistent findings in abscesses, we used...


    pub_type: 杂志文章


    authors: Guo AC,Provenzale JM,Cruz LC Jr,Petrella JR

    更新日期:2001-05-01 00:00:00

  • Lumbar percutaneous discectomy. Initial experience in 28 cases.

    abstract::Since November 1988, 28 patients with lumbar L5 radiculopathy refractory to conservative care and with a radiologically verified central or mediolateral disc herniation at the level of L4/L5 had had a percutaneous discectomy. Radiological verification consisted of spinal CT +/- myelography, +/- myelo-CT, +/- MRI. A sh...


    pub_type: 杂志文章


    authors: Faubert C,Caspar W

    更新日期:1991-01-01 00:00:00

  • Primary leiomyosarcoma of the spine.

    abstract::We present a 39-year-old man with tumour of the eighth thoracic vertebra, causing compression of the spinal cord. The tumour proved to be a primary leiomyosarcoma (LMS) of bone, an uncommon neoplasm; to our knowledge this is the first report of primary LMS in the spine. The lesion was documented by plain radiography, ...


    pub_type: 杂志文章


    authors: Lo TH,van Rooij WJ,Teepen JL,Verhagen IT

    更新日期:1995-08-01 00:00:00

  • Magnification angiography of dural carotid-cavernous sinus fistulae with emphasis on clinical and angiographic evolution.

    abstract::Eleven patients with dural carotid-cavernous sinus fistulae were studied with selective magnification angiography. The angiographic features of this condition were analyzed in detail. The arterial plexus normally present in and around the cavernous sinus has been thought to rupture into the sinus and establish an arte...


    pub_type: 杂志文章


    authors: Takahashi M,Nakano Y

    更新日期:1980-01-01 00:00:00

  • Retrograde filling of the anterior choroidal artery: vertebral angiographic sign of obstruction in the carotid system.

    abstract::Retrograde filling of seven anterior choroidal arteries from the posterior circulation was observed on a vertebral angiogram in six patients with occlusion of the proximal anterior choroidal artery or of the internal carotid artery. In one patient with thrombotic occlusion of the internal carotid artery, the enlarged ...


    pub_type: 杂志文章


    authors: Takahashi S,Tobita M,Takahashi A,Sakamoto K

    更新日期:1992-01-01 00:00:00

  • Endovascular treatment of intracranial aneurysms with the p64 flow diverter stent: mid-term results in 35 patients with 41 intracranial aneurysms.

    abstract:INTRODUCTION:The p64 flow diverter (FD) device is a fully resheathable and detachable stent dedicated for endovascular treatment (EVT) of intracranial aneurysms (IAs). We report our mid-term experience with this device. METHODS:Between January 2015 and February 2016, we retrospectively identified, in our prospectively...


    pub_type: 杂志文章


    authors: Morais R,Mine B,Bruyère PJ,Naeije G,Lubicz B

    更新日期:2017-03-01 00:00:00

  • Facial nerve neuromas: MR imaging. Report of four cases.

    abstract::Four cases of facial nerve neuroma were evaluated by computed tomographic (CT) scan and magnetic resonance imaging (MRI). The extension of the tumor in the petrous bone or the parotid gland was well defined by MRI in all cases. CT scan was useful to demonstrate bone erosions and the relation of the tumor to inner ear ...


    pub_type: 杂志文章


    authors: Martin N,Sterkers O,Mompoint D,Nahum H

    更新日期:1992-01-01 00:00:00

  • Air bubbles in the subclavian or internal jugular veins: a common finding on contrast-enhanced CT.

    abstract::We investigated the frequency of air bubbles in the subclavian (SCV) or internal jugular (IJV) vein in 200 patients who underwent contrast-enhanced CT of the head and neck. Half the patients were reviewed retrospectively (group 1), while the other half were investigated prospectively after the radiologists who adminis...


    pub_type: 杂志文章


    authors: Sakai O,Nakashima N,Shinozaki T,Furuse M

    更新日期:1998-04-01 00:00:00

  • Comparison between stenting and conservative management of posterior circulation perforator aneurysms: Systematic review and case series.

    abstract:PURPOSE:Posterior circulation perforator aneurysms (PCPAs) are a rare type of intracranial aneurysms whose natural history and optimal clinical management are still largely unexplored. This study aims to report our experience with treating ruptured PCPAs and to provide a systematic review of the literature to compare t...


    pub_type: 杂志文章,评审


    authors: Gardijan D,Herega T,Premužić V,Jovanović I,Ozretić D,Poljaković Z,Radoš M

    更新日期:2021-01-06 00:00:00

  • Potentiation of Amipaque epileptogenic activity by neuroleptics.

    abstract::Experiments conducted on rabbits confirmed that chlorpromazine potentiates the weak epileptogenic action of Amipaque (metrizamide). Chlorpromazine withdrawal for a period of 48 h suppresses this potentiating effect in the rabbit. Neuroleptic drugs should therefore be avoided in patients examined with Amipaque. In pati...


    pub_type: 杂志文章


    authors: Gonsette RE,Brucher JM

    更新日期:1977-08-25 00:00:00

  • Magnetic resonance imaging of uveitis.

    abstract:INTRODUCTION:Uveitis is a term used to describe inflammation of the choroid, iris, or ciliary body, which make up the uveal tract. It can be idiopathic or associated with a systemic disease which may be infectious or noninfectious. With the exception of B-scan ultrasonography, current imaging methods for diagnosing and...


    pub_type: 杂志文章,评审


    authors: Li CQ,Cho AA,Edward NJ,Edward DP,Fajardo RG,Mafee MF

    更新日期:2015-08-01 00:00:00

  • MR signal of the solid portion of pilocytic astrocytoma on T2-weighted images: is it useful for differentiation from medulloblastoma?

    abstract:BACKGROUND AND PURPOSE:Although imaging features of cerebellar pilocytic astrocytoma and medulloblastoma have been described in many texts, original comparisons of magnetic resonance intensity between these two tumours are limited. In the present study the results of magnetic resonance imaging (MRI) were reviewed, focu...


    pub_type: 杂志文章


    authors: Arai K,Sato N,Aoki J,Yagi A,Taketomi-Takahashi A,Morita H,Koyama Y,Oba H,Ishiuchi S,Saito N,Endo K

    更新日期:2006-04-01 00:00:00

  • Stent-assisted angioplasty for intracranial atherosclerosis.

    abstract::We report on two patients with intracranial atherosclerosis of the carotid artery or vertebral artery treated with stent-assisted angioplasty. Both patients have severe intracranial atherosclerosis (>70%) with refractory symptoms despite optimal medical treatment. In both patients, a coronary balloon-expandable stent ...


    pub_type: 杂志文章


    authors: Nakahara T,Sakamoto S,Hamasaki O,Sakoda K

    更新日期:2002-08-01 00:00:00

  • Tumour blood flow and partition coefficients: correlation with grade of cerebral gliomas using xenon-enhanced computed tomography.

    abstract::It is possible to underestimate the grade of nonenhancing cerebral tumours on conventional contrast-enhanced MRI or CT. Differentiation of high- and low-grade gliomas by measurement of the brain-blood partition coefficient lambda (T lambda) with Xe-enhanced CT (XeCT) has been reported. We assessed the practical applic...


    pub_type: 杂志文章


    authors: Nasel C,Rössler K,Heimberger K,Görzer H,Lassmann H,Schindler E

    更新日期:1997-09-01 00:00:00

  • Vertebral arteriovenous fistula: endovascular treatment with electrodetachable coils.

    abstract::We report a patient with an iatrogenic vertebro-vertebral fistula responsible for a cerebellar syndrome and a cervical bruit. Endovascular treatment of the fistula was carried out using electrically detachable coils. An angiogram 5 months after treatment showed that the fistula had totally disappeared. ...


    pub_type: 杂志文章


    authors: Miralbés S,Cattin F,Andrea I,Bonneville JF

    更新日期:1998-11-01 00:00:00

  • CT of malignant choroidal melanoma - morphology and perfusion characteristics.

    abstract::The computed tomographic morphology of malignant choroidal melanoma and its perfusion characteristics are described. Thirty-three static and serial CT examinations made on 29 patients with choroidal melanoma, three with pseudotumors of the macula and one with choroidal metastasis revealed the choroidal melanoma to be ...


    pub_type: 杂志文章


    authors: Heller M,Guthoff R,Hagemann J,Jend HH

    更新日期:1982-01-01 00:00:00

  • Double microcatheter technique for endovascular coiling of wide-neck aneurysms using a new guiding device for the transcarotid approach: technical note.

    abstract::In the endovascular treatment of cerebrovascular diseases, positioning the guiding catheter is of great importance. In cases where vessel tortuosity prohibits positioning the guiding catheter in the carotid artery via the femoral approach, we use a direct carotid approach via common carotid artery puncture. For direct...


    pub_type: 杂志文章


    authors: Kai Y,Hamada J,Morioka M,Yano S,Mizuno T,Kuratsu J

    更新日期:2005-01-01 00:00:00

  • Correction to: Magnetic resonance imaging features of the superior cervical ganglion and expected changes after radiation therapy to the head and neck in a long-term follow-up.

    abstract::In the article "Magnetic resonance imaging features of the superior cervical ganglion and expected changes after radiation therapy to the head and neck in a long-term follow-up", one of the author names, K Chokkappan, was spelled incorrectly. ...


    pub_type: 已发布勘误


    authors: Ravanelli M,Tononcelli E,Leali M,Buffa I,Loke SC,Karandikar A,Chokkappan K,Yue GOC,Goh JPN,Tan TY,Farina D

    更新日期:2020-06-01 00:00:00

  • Combined interventional stroke therapy using intracranial stent and local intraarterial thrombolysis (LIT).

    abstract:INTRODUCTION:Supported by results of the ECASS III study, intravenous rt-PA thrombolysis is considered a standard therapy for acute stroke within 4.5 h. Still under debate is the use of a more aggressive treatment as that of local intraarterial thrombolysis (LIT) or combining intravenous administration of recombinant t...


    pub_type: 杂志文章


    authors: Seifert M,Ahlbrecht A,Dohmen C,Spuentrup E,Moeller-Hartmann W

    更新日期:2011-04-01 00:00:00

  • Airbag deployment and cervical spine injury in restrained drivers following motor vehicle collisions.

    abstract:PURPOSE:Seatbelts and airbags are the most important devices protecting drivers from cervical spine injury (CSI) following motor vehicle collisions (MVCs). However, there have been few reports on the radiographic characteristics of CSI sustained by restrained, airbag-deployed drivers. METHODS:A single-center, retrospe...


    pub_type: 杂志文章


    authors: Inamasu J,Kato M

    更新日期:2018-12-01 00:00:00

  • Cerebral amyloid angiopathy with focal presentation-about 3 cases.

    abstract::Cerebral amyloid angiopathy (CAA) is a common cerebrovascular disease involved in ischemic and hemorrhagic strokes, and its progression is correlated to cognitive decline. In vivo diagnosis of CAA is guided by the modified Boston criteria, with the presence of multiple intracerebral hemorrhage or cerebral microbleeds ...


    pub_type: 杂志文章


    authors: Garnier-Crussard A,Taki A,Bonnefoy M,Bar JY,Krolak-Salmon P,Cotton F,Gilbert T

    更新日期:2020-09-01 00:00:00

  • Radiology of the ambient cistern. Part I: Normal.

    abstract::The angiographic and high-resolution, thin-section CT appearance of the normal ambient cistern is correlated with anatomic dissections and sections of normal, formalin-fixed cadaver brains. Each of three separate anatomic segments of the ambient cistern--the supratentorial segment, the tentorial edge and the subtentor...


    pub_type: 杂志文章


    authors: Chakeres DW,Kapila A

    更新日期:1985-01-01 00:00:00

  • Posterior lumbar apophyseal ring fractures: a report of 20 cases.

    abstract::Posterior apophyseal ring fracture (PARF) of the lumbar spine is an uncommon injury thought usually to occur in adolescence. We analysed CT findings in 20 cases (19 patients), whose age ranged from 16 to 45 years (average 30 years). The PARF could be divided into two distinct groups on the basis of the shape and locat...


    pub_type: 杂志文章


    authors: Yang IK,Bahk YW,Choi KH,Paik MW,Shinn KS

    更新日期:1994-08-01 00:00:00

  • Functional brain networks involved in decision-making under certain and uncertain conditions.

    abstract:PURPOSE:The aim of this study was to describe imaging markers of decision-making under uncertain conditions in normal individuals, in order to provide baseline activity to compare to impaired decision-making in pathological states. METHODS:In this cross-sectional study, 19 healthy subjects ages 18-35 completed a novel...


    pub_type: 杂志文章


    authors: Farrar DC,Mian AZ,Budson AE,Moss MB,Killiany RJ

    更新日期:2018-01-01 00:00:00

  • Comparison of echo-planar sequences for perfusion-weighted MRI: which is best?

    abstract::We compared gradient-echo (GRE), spin-echo (SE) and stimulated-echo (STE) echo-planar imaging sequences for perfusion-weighted imaging at different field strengths. Focal cerebral ischaemia was induced by endovascular occlusion of the middle cerebral artery in eight rats. MR was performed at 4.7 T or 2.35 T. With each...


    pub_type: 杂志文章


    authors: Heiland S,Kreibich W,Reith W,Benner T,Dörfler A,Forsting M,Sartor K

    更新日期:1998-04-01 00:00:00

  • Role of stenosis of spinal canal in L4-L5 nerve root compression assessed by flexion-extension myelography.

    abstract::Myelographic flexion-extension studies were performed in four groups of 10 patients each, with (A) normal myelogram; (B) bilateral nerve root compression at L4-L5; (C) unilateral nerve root compression at L4-L5 and (D) nerve root compression at L5-S1. The aim of the investigation was to assess the role of spinal steno...


    pub_type: 杂志文章


    authors: Wilmink JT,Penning L,van den Burg W

    更新日期:1984-01-01 00:00:00

  • CT intracranial localization with a new marker system.

    abstract::Application of a new CT localization system for intracranial lesions in pre- and intraoperative guidance is described. This system consists of air grooves within an acrylic plate for CT examinations and a duplicate plate with wires in place of air grooves for scout radiography. This new device can also be applied in s...


    pub_type: 杂志文章


    authors: Lee SH,Villafana T,Lapayowker MS

    更新日期:1978-01-01 00:00:00