Endometrial clear cell carcinoma metastatic to the paranasal sinuses: a case report and review of the literature.


BACKGROUND:Paranasal sinus metastasis following endometrial carcinoma is extremely rare and a reflection of disseminated disease. CASE:We report a case of a 72-year-old woman who presented ethmoid and sphenoid sinus metastasis, 14 months after total abdominal hysterectomy and bilateral salpingo-oophorectomy due to an endometrial clear cell carcinoma. CONCLUSION:One should recognize the possibility of a metastatic disease to the sinuses in patients presenting with associated symptoms.


Gynecol Oncol


Gynecologic oncology


Ilvan S,Akyildiz EU,Calay Z,Celikoyar M,Sahinler I




Has Abstract


2004-07-01 00:00:00














  • Nucleolar organizer regions in endometriosis, atypical endometriosis, and clear cell and endometrioid carcinomas.

    abstract::Nucleolar Organizer Regions (NORs) code for ribosomal RNA and are thought to be an accurate representation of the percentage of cells in S-phase. NORs are associated with nonhistone nucleoproteins, which can be stained with silver (AgNORs). An increased number of AgNORs has been observed in many malignancies. AgNORs w...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Chalas E,Chumas J,Barbieri R,Mann WJ

    更新日期:1991-03-01 00:00:00

  • 10-Gy single-fraction pelvic irradiation for palliation and life prolongation in patients with cancer of the cervix and corpus uteri.

    abstract:OBJECTIVE:The goal of this study was to evaluate the effects of single fractions of 10 Gy pelvic irradiation for palliation and life prolongation in patients with cancer of the uterine cervix or corpus. METHODS:A retrospective analysis was performed on 37 cervical cancer and 27 corpus cancer patients treated in the pe...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Onsrud M,Hagen B,Strickert T

    更新日期:2001-07-01 00:00:00

  • Angiogenesis in endometrial carcinoma: Therapies and biomarkers, current options, and future perspectives.

    abstract::Endometrial carcinoma is the most common gynecologic malignancy and the fourth most prevalent cancer in women in the modern world. Despite a relatively high chance of surgical cure, for patients with advanced or recurrent disease there are few therapeutic options. Angiogenesis has been extensively studied ever since v...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,评审


    authors: Berger AA,Dao F,Levine DA

    更新日期:2020-12-26 00:00:00

  • Mortality reduction and cost-effectiveness of performing hysterectomy at the time of risk-reducing salpingo-oophorectomy for prophylaxis against serous/serous-like uterine cancers in BRCA1 mutation carriers.

    abstract:OBJECTIVE:To estimate the survival benefit and cost-effectiveness of performing hysterectomy during risk-reducing salpingo-oophorectomy (RRSO) for BRCA1 mutation carriers. METHODS:Based on a recent prospective cohort study indicating an elevated incidence of serous/serous-like uterine cancers among BRCA1 mutation carr...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Havrilesky LJ,Moss HA,Chino J,Myers ER,Kauff ND

    更新日期:2017-06-01 00:00:00

  • Contribution of human papillomavirus testing by hybrid capture in the triage of women with repeated abnormal pap smears before colposcopy referral.

    abstract:OBJECTIVE:The purpose of this work was to evaluate the ability of testing for high-risk human papillomavirus (HPV) types using the hybrid capture technique to predict the presence of cervical intraepithelial neoplasia (CIN) II,III in patients with repeated atypical squamous cells of undetermined significance (ASCUS) an...

    journal_title:Gynecologic oncology

    pub_type: 临床试验,杂志文章


    authors: Fait G,Kupferminc MJ,Daniel Y,Geva E,Ron IG,Lessing JB,Bar-Am A

    更新日期:2000-11-01 00:00:00

  • Role of an early second-look laparotomy in ovarian cancer.

    abstract::Of a group of 68 patients treated with standard polychemotherapy (CAP-5), 52 were evaluated by an early second-look laparotomy, preferably after three cycles of treatment. Of 21 patients with initial tumor residuals smaller than 2 cm, only 5 had residual tumor, and of 31 patients with tumor larger than 2 cm, 27 had re...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: van Lith JM,Bouma J,Aalders JG,Boonstra H,Sleijfer DT,Willemse PH

    更新日期:1989-11-01 00:00:00

  • Evaluation of the performance of the ACS NSQIP surgical risk calculator in gynecologic oncology patients undergoing laparotomy.

    abstract:OBJECTIVE:The objective of this study was to evaluate the ability of the American College of Surgeons (ACS) National Surgical Quality Improvement Program (NSQIP) surgical risk calculator to predict complications in gynecologic oncology patients undergoing laparotomy. METHODS:A chart review of patients who underwent la...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Rivard C,Nahum R,Slagle E,Duininck M,Isaksson Vogel R,Teoh D

    更新日期:2016-05-01 00:00:00

  • Osseous metaplasia in ovarian papillary serous cystadenocarcinoma.

    abstract::The finding of osseous metaplasia within an ovarian papillary serous cystadenocarcinoma is very rare. A review of the medical literature reveals only two previously published cases where mature bone was found in an ovarian serous cystadenocarcinoma. This report presents an additional case of this unusual phenomenon wh...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Bosscher J,Barnhill D,O'Connor D,Doering D,Nash J,Park R

    更新日期:1990-11-01 00:00:00

  • A prospective study evaluating the clinical relevance of a chemoresponse assay for treatment of patients with persistent or recurrent ovarian cancer.

    abstract:OBJECTIVE:Use of in vitro chemoresponse assays for informing effective treatment selection is a compelling clinical question and a topic of debate among oncologists. A prospective study was conducted evaluating the use of a chemoresponse assay in recurrent ovarian cancer patients. METHODS:Women with persistent or recu...

    journal_title:Gynecologic oncology

    pub_type: 临床试验,杂志文章


    authors: Rutherford T,Orr J Jr,Grendys E Jr,Edwards R,Krivak TC,Holloway R,Moore RG,Puls L,Tillmanns T,Schink JC,Brower SL,Tian C,Herzog TJ

    更新日期:2013-11-01 00:00:00

  • Advanced cervical carcinoma presenting with toxic shock syndrome.

    abstract::Toxic shock syndrome is a multisystem disease which presents with a high fever, rash, gastrointestinal symptoms, and hypotension. A 58-year-old woman presented to the emergency room with these symptoms, hypotension and tachycardia. Because of vaginal spotting a pelvic examination was performed which demonstrated vulvo...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Rose PG,Wilson G

    更新日期:1994-02-01 00:00:00

  • Management of high-grade stage I adenocarcinoma of the endometrium: hysterectomy following low dose external beam pelvic irradiation.

    abstract::Sixty-eight patients with FIGO stage I, grade 2 or 3 adenocarcinoma of the endometrium were treated according to a protocol involving 10 Gy external pelvic irradiation, prompt hysterectomy with surgical staging, and postoperative therapy individualized according to surgical-pathologic findings. Five-year survival for ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Shimm DS,Wang CC,Fuller AF Jr,Nelson JH Jr,Nikrui N,Young RH,Scully RE

    更新日期:1986-02-01 00:00:00

  • Stage II endometrial carcinoma: prognostic factors and the results of treatment.

    abstract::Results of treatment and potential prognostic factors in 54 patients with clinical stage II endometrial carcinoma were analyzed. During the period analyzed, three different treatment techniques were used. The highest cure rate (70.6%) was observed in patients treated with simple hysterectomy and bilateral salpingo-oop...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Andersen ES

    更新日期:1990-08-01 00:00:00

  • Psychological impact of prophylactic oophorectomy in women at increased risk of developing ovarian cancer: a prospective study.

    abstract:OBJECTIVES:The objectives of this study were twofold: to prospectively assess whether expressed intention to undergo prophylactic oophorectomy translated into uptake and to evaluate the psychological impact of the procedure in a sample of unaffected women with a strong family history of breast/ovarian cancer. METHODS:...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Tiller K,Meiser B,Butow P,Clifton M,Thewes B,Friedlander M,Tucker K

    更新日期:2002-08-01 00:00:00

  • Radiotherapy and/or chemotherapy as adjuvant treatment of uterine sarcomas.

    abstract::A retrospective evaluation of 87 cases of uterine sarcoma treated during 1965-1980 at two Swedish hospitals has been made. Adjuvant postoperative radiotherapy has been compared with adjuvant chemotherapy. Various types of combination treatments were also evaluated. Both types of adjuvant therapy seem to reduce the fai...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Sorbe B

    更新日期:1985-03-01 00:00:00

  • A case of successful pregnancy after treatment of invasive cervical cancer with systemic chemotherapy and conization.

    abstract:BACKGROUND:The standard therapy for invasive uterine cervical cancer causes loss of the woman's fertility. We report a successful pregnancy in a patient who desired fertility-sparing management of invasive cervical cancer and was treated with systemic chemotherapy and conization. CASE:A 28-year-old nulliparous woman w...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Kobayashi Y,Akiyama F,Hasumi K

    更新日期:2006-01-01 00:00:00

  • Factors that influence survival in high-grade serous ovarian cancer: A complex relationship between molecular subtype, disease dissemination, and operability.

    abstract:OBJECTIVE:To investigate the relationship between molecular subtype, intraperitoneal (IP) disease dissemination patterns, resectability, and overall survival (OS) in advanced high-grade serous ovarian cancer (HGSOC). METHODS:Patients undergoing primary surgery for stage III-IV HGSOC at Mayo Clinic from 1994 to 2011 we...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Torres D,Wang C,Kumar A,Bakkum-Gamez JN,Weaver AL,McGree ME,Konecny GE,Goode EL,Cliby WA

    更新日期:2018-08-01 00:00:00

  • Participation of the general gynecologist in surgical staging of endometrial cancer: analysis of cost and perioperative outcomes.

    abstract:OBJECTIVE:To compare the cost and perioperative outcomes of endometrial cancer staging when the procedure is performed by a gynecologic oncologist alone or when a general gynecologist participates in the procedure. METHODS:A retrospective analysis was performed on a series of women with clinical stage I endometrial ca...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Hoekstra A,Singh DK,Garb M,Arekapudi S,Rademaker A,Lurain JR

    更新日期:2006-12-01 00:00:00

  • Distribution of involucrin in normal and pathological human uterine cervix.

    abstract::A study was undertaken to determine the potential value of involucrin immunostaining, a protein synthesized by mature squamous epithelial cells, in distinguishing benign from neoplastic lesions in cervical pathology. A total of 146 cervical biopsies were analyzed using an indirect immunoperoxidase method and polyclona...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Serra V,Ramirez AA,Lara C,Marzo C,Castells A,Bonilla-Musoles F

    更新日期:1990-01-01 00:00:00

  • Evaluating class III antiarrhythmic agents as novel MYC targeting drugs in ovarian cancer.

    abstract:OBJECTIVE:To evaluate the utility of amiodarone and its derivative dronedarone as novel drug repositioning candidates in EOC and to determine the potential pathways targeted by these drugs. METHODS:Drug-predict bioinformatics platform was used to assess the utility of amiodarone as a novel drug-repurposing candidate i...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Belur Nagaraj A,Joseph P,Kovalenko O,Wang Q,Xu R,DiFeo A

    更新日期:2018-12-01 00:00:00

  • Health related quality of life and symptoms after pelvic lymphadenectomy or radiotherapy vs. no adjuvant regional treatment in early-stage endometrial carcinoma: a large population-based study.

    abstract:OBJECTIVES:Routine lymphadenectomy (LA) in early stage endometrial cancer does not improve survival. However, in the absence of lymph node metastasis, radiotherapy (RT) could be withheld and hence could result in less morbidity. Our aim was to evaluate health related quality of life (HRQL) in endometrial cancer survivo...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: van de Poll-Franse LV,Pijnenborg JM,Boll D,Vos MC,van den Berg H,Lybeert ML,de Winter K,Kruitwagen RF

    更新日期:2012-10-01 00:00:00

  • Brain metastases in patients with EOC: Clinico-pathological and prognostic factors. A multicentric retrospective analysis from the MITO group (MITO 19).

    abstract:BACKGROUND:Brain metastases (BM) from epithelial ovarian cancer (EOC) are considered a rare and unfavourable event. There is no consensus regarding the best management of these patients. METHODS:A multicenter retrospective analysis of patients with BM from EOC treated between 1997 and 2014 in 18 institutions of the MI...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,多中心研究


    authors: Marchetti C,Ferrandina G,Cormio G,Gambino A,Cecere S,Lorusso D,De Giorgi U,Bogliolo S,Fagotti A,Mammoliti S,Narducci F,Bergamini A,Scollo P,Biglia N,Breda E,Tamberi S,Marinaccio M,Angioli R,Salerno L,Eusebi MC,Loi

    更新日期:2016-12-01 00:00:00

  • Malignant struma ovarii with Graves' disease.

    abstract:BACKGROUND:Malignant struma ovarii is a rare tumor, consisting of a struma ovarii with malignant change. Because of the rarity of the tumor, only a few reports with detailed data of thyroid function of the patient have been published. CASE:Medical and surgical treatments were performed in a case of malignant struma ov...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Kano H,Inoue M,Nishino T,Yoshimoto Y,Arima R

    更新日期:2000-12-01 00:00:00

  • Control of cyclin D1 expression by antisense oligonucleotides in three ovarian cancer cell lines.

    abstract::Cyclin D1 is a critical gene controlling the G1 phase progression through the cell cycle. Alterations of cyclin D1 have been demonstrated in a variety of cancer types. We recently reported that increased cyclin D1 expression is associated with malignancy also in ovarian tumors. Three human ovarian cancer cell lines (S...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Cagnoli M,Barbieri F,Bruzzo C,Alama A

    更新日期:1998-09-01 00:00:00

  • Primary peritoneal psammocarcinoma: a case presenting synchronously with bowel carcinoma.

    abstract:BACKGROUND:Psammocarcinomas are rare epithelial tumors usually originating from the ovarian surface epithelium or the peritoneum. In our case, a peritoneal psammocarcinoma was incidental surgical finding during laparotomy. CASE:An 83-year-old woman underwent surgery for bowel obstruction. Intraoperativelly, a bowel ca...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Koumoundourou D,Michail G,Kourounis G,Ravazoula P

    更新日期:2006-09-01 00:00:00

  • Optimal surgical cytoreduction in patients with Stage III and Stage IV endometrial carcinoma: a study of morbidity and survival.

    abstract:OBJECTIVE:To evaluate the survival impact of residual disease at the time of primary surgery for patients with Stage III and IV endometrial carcinoma; to assess morbidity associated with surgical cytoreduction. METHOD:All patients with endometrial carcinoma who underwent primary surgical therapy at the University of M...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Lambrou NC,Gómez-Marín O,Mirhashemi R,Beach H,Salom E,Almeida-Parra Z,Peñalver M

    更新日期:2004-06-01 00:00:00

  • Concomitant endometrial hyperplasia in patients with endometrial carcinoma.

    abstract:OBJECTIVES:The aim of this study was to compare the histopathologic features and prognosis of patients with endometrial carcinoma with and without concomitant hyperplasia. METHODS:Histologic slides of the surgical specimens of 214 consecutive patients who underwent surgery as primary treatment for endometrial carcinom...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Gücer F,Reich O,Tamussino K,Bader AA,Pieber D,Schöll W,Haas J,Petru E

    更新日期:1998-04-01 00:00:00

  • Lower uterine segment involvement as a predictor for lymph node spread in endometrial carcinoma.

    abstract:OBJECTIVES:Several predictive factors for lymph node spread in endometrial cancer have been identified including tumor grade, depth of invasion, lymphatic or vascular-space invasion, and histologic subtype. Lower uterine segment involvement may also be predictive of lymph node spread. The objective of this study was to...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Madom LM,Brown AK,Lui F,Moore RG,Granai CO,Disilvestro PA

    更新日期:2007-10-01 00:00:00

  • Etiologic heterogeneity in endometrial cancer: evidence from a Gynecologic Oncology Group trial.

    abstract:OBJECTIVE:Although the epidemiology of typical endometrial carcinomas (grades 1-2 endometrioid or Type I) is well established, less is known regarding higher grade endometrioid or non-endometrioid carcinomas (Type II). Within a large Gynecologic Oncology Group trial (GOG-210), which included central pathology review, w...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,多中心研究


    authors: Brinton LA,Felix AS,McMeekin DS,Creasman WT,Sherman ME,Mutch D,Cohn DE,Walker JL,Moore RG,Downs LS,Soslow RA,Zaino R

    更新日期:2013-05-01 00:00:00

  • Three-dimensional coculture of endometrial cancer cells and fibroblasts in human placenta derived collagen sponges and expression matrix metalloproteinases in these cells.

    abstract:OBJECTIVE:Collagen gel constitutes a valuable tool for the study of cell-matrix interactions; however, it is sometimes difficult to use the gel, in which tumor and stromal cells are cocultured, for immunohistochemistry, because it is easily broken during the process of fixation and embedding in paraffin, especially aft...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Tanaka R,Saito T,Ashihara K,Nishimura M,Mizumoto H,Kudo R

    更新日期:2003-08-01 00:00:00

  • Tumor budding and E-Cadherin expression in endometrial carcinoma: are they prognostic factors in endometrial cancer?

    abstract:OBJECTIVE:To evaluate the prognostic value of tumor budding (TB) in endometrioid (EEC) and non-endometrioid endometrial cancers (NEEC) and to determine its correlation with expression of E-cadherin. METHODS:Ninety-five patients with primary endometrial carcinoma were examined statistically. All patients were diagnosed...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Koyuncuoglu M,Okyay E,Saatli B,Olgan S,Akin M,Saygili U

    更新日期:2012-04-01 00:00:00