Intracranial metastases from carcinoma cervix and review of literature.


:Brain metastases from primary cervical carcinoma are uncommon. Only 41 cases have been reported so far in the English literature. We have seen 2 cases over the last 2 years among 481 patients with cervical cancer. Brain metastases developed 7 and 35 months after the primary diagnosis. One patient with solitary metastasis had no evidence of disease elsewhere and is free of disease after surgery and radiation therapy 7 months after the brain metastasis. Another patient with multiple brain metastases and cervical disease is alive 2 months after palliative radiation therapy.


Gynecol Oncol


Gynecologic oncology


Kumar L,Tanwar RK,Singh SP




Has Abstract


1992-09-01 00:00:00












  • Long-term survival in an ovarian cancer patient with brain metastases.

    abstract:BACKGROUND:Central nervous system (CNS) metastases from ovarian adenocarcinoma are uncommon. The long-term prognosis for these patients is poor, with studies reporting a mean survival of less than 12 months. CASE:We present a case involving a 57-year-old woman diagnosed and treated for primary ovarian cancer in 1994. ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Micha JP,Goldstein BH,Hunter JV,Rettenmaier MA,Brown JV

    更新日期:2004-03-01 00:00:00

  • Clinical outcome of neoadjuvant chemotherapy for advanced ovarian cancer.

    abstract:OBJECTIVE:To evaluate clinical outcome in patients selected to receive neoadjuvant chemotherapy (NACT) compared to primary debulking surgery (PDS). METHODS:Retrospective study including all consecutive patients diagnosed and treated for advanced (stages III-IV) ovarian cancers between the years 2003-2015. RESULTS:263...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Kessous R,Laskov I,Abitbol J,Bitharas J,Yasmeen A,Salvador S,Lau S,Gotlieb WH

    更新日期:2017-03-01 00:00:00

  • Atypical endometrial hyperplasia treatment with progestogens and gonadotropin-releasing hormone analogues: long-term follow-up.

    abstract:OBJECTIVE:The aim of this study was to assess the long-term effect of gonadotropin-releasing hormone analogues (GnRH-a) in combination with high-dose progestogens in the treatment of atypical endometrial hyperplasia in selected surgical high-risk patients and in women desiring reproductive potential. We hypothesized th...

    journal_title:Gynecologic oncology

    pub_type: 临床试验,杂志文章


    authors: Pérez-Medina T,Bajo J,Folgueira G,Haya J,Ortega P

    更新日期:1999-05-01 00:00:00

  • Transvaginal evisceration of small bowel after radical hysterectomy and pelvic lymphadenectomy.

    abstract::Vaginal evisceration is a rare event. This case report describes a 45-year-old woman who presented 8 days following radical hysterectomy and lymph node dissection for stage 1B squamous cell carcinoma of the cervix with small bowel evisceration through the vagina. She was treated by laparotomy and resection anastamosis...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,评审


    authors: Dawlatly B,Lavie O,Lopes A

    更新日期:1999-04-01 00:00:00

  • Glutathione S-transferase polymorphisms and ovarian cancer treatment and survival.

    abstract:OBJECTIVE:Members of the glutathione S-transferase (GST) family have been shown to have functional polymorphisms that may affect drug metabolism and influence the effects of chemotherapy and survival from cancer. GSTM1, GSTT1, and GSTP1 genotypes were evaluated for their role in ovarian cancer treatment and survival. ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Beeghly A,Katsaros D,Chen H,Fracchioli S,Zhang Y,Massobrio M,Risch H,Jones B,Yu H

    更新日期:2006-02-01 00:00:00

  • Liquid-based cytology and human papillomavirus testing: a pooled analysis using the data from 13 population-based cervical cancer screening studies from China.

    abstract:OBJECTIVE:The objective of this study was to evaluate the impact of introducing HR-HPV testing in cytology regarding cervical cancer screening practice. METHODS:A pooled analysis of liquid-based cytology (LBC) and HR-HPV testing using data from 13 population-based cervical cancer screening studies conducted in China w...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,meta分析


    authors: Pan QJ,Hu SY,Guo HQ,Zhang WH,Zhang X,Chen W,Cao J,Jiang Y,Zhao FH,Qiao YL

    更新日期:2014-05-01 00:00:00

  • Detection of human papillomavirus DNA in malignant lesions from Chinese women with carcinomas of the upper genital tract.

    abstract:OBJECTIVE:The aim of this study was to determine the prevalence of high-risk oncogenic human papillomaviruses (HPVs) in malignant lesions from Hong Kong Chinese women with carcinomas of the upper genital tract. METHODS:The presence of high-risk HPVs in 55 cases of endometrial adenocarcinomas and 60 cases of primary ep...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Ip SM,Wong LC,Xu CM,Cheung AN,Tsang PC,Ngan HY

    更新日期:2002-10-01 00:00:00

  • Primary vaginal adenosarcoma with sarcomatous overgrowth.

    abstract:BACKGROUND:Primary vaginal adenosarcomas are extremely rare, and typical adenosarcomas are of low malignancy. However, aggressive forms with sarcomatous overgrowth have been reported, those appear to have a poor prognosis. CASE:A 52-year-old woman who had undergone prior surgery for uterine leiomyoma and an ovarian cy...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Toyoshima M,Akahira J,Moriya T,Hayakawa S,Yaegashi N

    更新日期:2004-12-01 00:00:00

  • Interphase AgNOR quantity and DNA content in endometrial adenocarcinoma.

    abstract::The relationship between the amount of silver-stained nucleolar organizer regions (AgNORs) and the DNA content of interphase neoplastic cells in 63 cases of human endometrial adenocarcinoma was studied. Interphase AgNOR content was determined as the mean AgNOR area per nucleus by image cytometry in silver-stained samp...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Trerè D,Melchiorri C,Chieco P,Marabini A,Derenzini M

    更新日期:1994-05-01 00:00:00

  • Treatment of malignant ascites with allogeneic and autologous lymphokine-activated killer cells.

    abstract::Two cases of peritonitis carcinomatosa with gynecological cancer, which did not respond to conventional treatment, were treated by intraperitoneal adoptive immunotherapy with allogeneic or autologous lymphokine-activated killer (LAK) cells plus interleukin-2. In case 1, reduction of acute ascites and disappearance of ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Kamada M,Sakamoto Y,Furumoto H,Mori K,Daitoh T,Irahara M,Aono T,Nii A,Yanagawa H,Sone S

    更新日期:1989-07-01 00:00:00

  • Body mass index, physical activity and quality of life of ovarian cancer survivors: time to get moving?

    abstract:OBJECTIVE:To evaluate the association between body mass index (BMI), physical activity (PA) and the quality of life (QoL) of ovarian cancer survivors. METHODS:We performed a two-centre cross-sectional study of women who had been treated for ovarian cancer between January 2007 and December 2014 at the Royal Cornwall Ho...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,多中心研究


    authors: Smits A,Smits E,Lopes A,Das N,Hughes G,Talaat A,Pollard A,Bouwman F,Massuger L,Bekkers R,Galaal K

    更新日期:2015-10-01 00:00:00

  • Brain metastasis in epithelial ovarian cancer by BRCA1/2 mutation status.

    abstract:OBJECTIVE:To evaluate clinical outcomes of patients with BRCA-associated ovarian cancer who developed brain metastases (BM). METHODS:Patients with epithelial ovarian, fallopian tube, and primary peritoneal cancer (EOC) and BM, treated at a single institution from 1/1/2008-7/1/2018, were identified from two institution...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Stasenko M,Cybulska P,Feit N,Makker V,Konner J,O'Cearbhaill RE,Alektiar KM,Beal K,Gardner GJ,Long Roche KC,Sonoda Y,Chi DS,Zivanovic O,Leitao MM Jr,Cadoo KA,Tew WP

    更新日期:2019-07-01 00:00:00

  • Targeting CD133 in an in vivo ovarian cancer model reduces ovarian cancer progression.

    abstract:OBJECTIVES:While most women with ovarian cancer will achieve complete remission after treatment, the majority will relapse within two years, highlighting the need for novel therapies. Cancer stem cells (CSC) have been identified in ovarian cancer and most other carcinomas as a small population of cells that can self-re...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Skubitz AP,Taras EP,Boylan KL,Waldron NN,Oh S,Panoskaltsis-Mortari A,Vallera DA

    更新日期:2013-09-01 00:00:00

  • Parametrial invasion of uterine cervical cancer assessed by transrectal ultrasonography: preliminary report.

    abstract::Transrectal ultrasonographic examinations were performed on 30 patients with uterine cervical cancer to assess parametrial invasion. The findings were compared with data obtained by manual rectal examination. Forty-six parametria in 23 patients were histologically examined following surgery. Sensitivity, specificity, ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Aoki S,Hata T,Senoh D,Makihara K,Hata K,Takamiya O,Kitao M

    更新日期:1990-01-01 00:00:00

  • Pseudo-Meigs' syndrome caused by a hydropic degenerating uterine leiomyoma with elevated CA 125.

    abstract:BACKGROUND:Uterine leiomyomas rarely cause pseudo-Meigs' syndrome with elevated serum CA 125 levels. CASE:A 39-year-old patient with a large uterine leiomyoma is described. The associated massive ascites, pleural fluid, and increased CA 125 level all seemed to be related to the uterine tumor. Hydropic degenerating lei...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Amant F,Gabriel C,Timmerman D,Vergote I

    更新日期:2001-10-01 00:00:00

  • Complications of combined radical hysterectomy-postoperative radiation therapy in women with early stage cervical cancer.

    abstract::Fifty patients with cervical cancer were treated with radical hysterectomy and lymphadenectomy followed by postoperative radiation therapy for high risk factors (nodal metastases, lymphvascular space invasion, close or involved margins) at the University of Alabama at Birmingham Medical Center from 1969 to 1984. Fifte...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Barter JF,Soong SJ,Shingleton HM,Hatch KD,Orr JW Jr

    更新日期:1989-03-01 00:00:00

  • Role of PET or PET/CT in the post-therapy surveillance of uterine sarcoma.

    abstract:OBJECTIVE:To evaluate the clinical accuracy and clinical impact of positron emission tomography (PET) or positron emission tomography/computed tomography (PET/CT) in detecting and treating tumor recurrence in patients with treated uterine sarcoma. METHODS:Results of 36 patients who underwent PET or PET/CT in post-ther...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Park JY,Kim EN,Kim DY,Suh DS,Kim JH,Kim YM,Kim YT,Nam JH

    更新日期:2008-05-01 00:00:00

  • Combined laparoscopic and vaginal surgery for the management of two cases of stage I endometrial cancer.

    abstract::Two postmenopausal patients with stage I adenocarcinoma of the endometrium who were managed with a combined laparoscopic and vaginal approach are presented. Surgical-pathologic staging was performed laparoscopically, with exploration of the abdomen and procurement of peritoneal cytology and pelvic and para-aortic lymp...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Childers JM,Surwit EA

    更新日期:1992-04-01 00:00:00

  • Gemcitabine and pegylated liposomal doxorubicin alternating with cisplatin plus cyclophosphamide in platinum refractory/resistant, paclitaxel-pretreated, ovarian carcinoma.

    abstract:OBJECTIVES:This phase II study conducted to investigate the efficacy and toxicity of the combination of gemcitabine (GEM) and pegylated liposomal doxorubicin (LDOX) alternating with cisplatin (CDDP) and cyclophosphamide (CTX) in platinum-resistant/refractory, paclitaxel pretreated epithelial ovarian cancer (EOC). PATI...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Pectasides D,Xiros N,Papaxoinis G,Aravantinos G,Sykiotis C,Pectasides E,Psyrri A,Koumarianou A,Gaglia A,Gouveris P,Economopoulos T

    更新日期:2008-01-01 00:00:00

  • Risk-based stratification of carcinomas concurrently involving the endometrium and ovary.

    abstract:OBJECTIVE:Determining whether carcinomas concurrently involving endometrium and ovary are independent primary tumors (IPTs) or endometrial carcinomas with ovarian metastases (at least stage IIIA endometrial cancers, IIIA-EC) using clinicopathologic criteria is often challenging. Recent genomic studies showed that most ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Turashvili G,Gómez-Hidalgo NR,Flynn J,Gonen M,Leitao MM Jr,Soslow RA,Murali R

    更新日期:2019-01-01 00:00:00

  • Hospital-acquired conditions after surgery for gynecologic cancer - An analysis of 82,304 patients.

    abstract:OBJECTIVE:To evaluate the hospital-acquired condition (HAC) following oophorectomy and/or hysterectomy for gynecologic cancer patients based on clinical outcomes and costs. MATERIALS AND METHODS:Data were obtained from the Nationwide Inpatient Sample from 2005 to 2011. Chi-squared and Wilcoxon rank sum two-sample test...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Chan JK,Gardner AB,Mann AK,Kapp DS

    更新日期:2018-09-01 00:00:00

  • The prognostic value of semiquantitative nuclear grading in endometrial carcinomas.

    abstract::The objective of this study was to evaluate the prognostic value of a convenient nuclear grading system based on only the proportion of nuclei measuring more than 10 microm in length at the shortest axis in endometrial carcinomas. Of the 235 cases reviewed, 9 serous and 5 clear cell adenocarcinomas and 2 small cell ca...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Hachisuga T,Kawarabayashi T,Iwasaka T,Sugimori H,Kamura T,Tsuneyoshi M

    更新日期:1997-04-01 00:00:00

  • HER2/neu gene amplification determines the sensitivity of uterine serous carcinoma cell lines to AZD8055, a novel dual mTORC1/2 inhibitor.

    abstract:OBJECTIVE:To evaluate c-erbB2 gene amplification in a series of primary uterine serous carcinoma (USC) cell lines. To assess the efficacy of AZD8055, a novel dual mTORC1/2 inhibitor against primary HER2/neu amplified vs HER2/neu not amplified USC cell lines. METHODS:Twenty-two primary USC cell lines were evaluated for...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: English DP,Roque DM,Carrara L,Lopez S,Bellone S,Cocco E,Bortolomai I,Schwartz PE,Rutherford T,Santin AD

    更新日期:2013-12-01 00:00:00

  • Primary jejunal adenocarcinoma masquerading as a primary ovarian malignancy.

    abstract::Primary adenocarcinoma of the jejunum which accounts for only approximately 3% of all gastrointestinal tract malignancies, is distinctly unusual. Ovarian metastasis from a jejunal cancer is extremely rare. It has significant therapeutic and prognostic implications to differentiate primary ovarian carcinoma from metast...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,评审


    authors: Tsuruchi N,Kubota H,Tsukamoto N,Kurano A

    更新日期:1995-07-01 00:00:00

  • Withdrawal from familial ovarian cancer screening for surgery: findings from a psychological evaluation study (PsyFOCS).

    abstract:OBJECTIVE:A prospective psychological evaluation study of familial ovarian cancer screening (PsyFOCS) is underway in partnership with the UK Familial Ovarian Cancer Screening Study (UK FOCSS Phase 2). One of the aims of PsyFOCS is to examine factors associated with withdrawal from the UK FOCSS prior to the onset of 4-m...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Lifford KJ,Fraser L,Rosenthal AN,Rogers MT,Lancastle D,Phelps C,Watson EK,Clements A,Iredale R,Jacobs I,Menon U,Brain KE

    更新日期:2012-01-01 00:00:00

  • Phase 2 trial of carboplatin plus tamoxifen in platinum-resistant ovarian cancer and primary carcinoma of the peritoneum.

    abstract:OBJECTIVES:A previously reported phase 2 trial suggested substantial clinical activity associated with the combination of a platinum agent and tamoxifen in the treatment of platinum-resistant ovarian cancer. We wished to confirm or refute this observation in a patient population with well-characterized platinum-resista...

    journal_title:Gynecologic oncology

    pub_type: 临床试验,杂志文章


    authors: Markman M,Webster K,Zanotti K,Peterson G,Kulp B,Belinson J

    更新日期:2004-08-01 00:00:00

  • Color Doppler and duplex flow analysis for classification of breast lesions.

    abstract::The purpose of this study was to evaluate the differences of blood supply in benign and malignant breast tumors by color Doppler flow measurements. The study included 471 patients, 133 with carcinomas, 325 with benign breast lesions, and 13 with mastitis. An ATL UM9/HDI was used with an electronic 10-MHz linear array ...

    journal_title:Gynecologic oncology

    pub_type: 临床试验,杂志文章


    authors: Madjar H,Sauerbrei W,Prömpeler HJ,Wolfarth R,Gufler H

    更新日期:1997-03-01 00:00:00

  • Breast cancer followed by corpus cancer: is there a higher risk for aggressive histologic subtypes?

    abstract:OBJECTIVE:To analyze corpus cancer patients with a breast cancer history for risk of developing aggressive uterine histologic types. METHODS:Corpus cancer patients with a history of breast cancer were identified from the Surveillance Epidemiology and End Results database from 1988 to 2001. Demographics, clinico-pathol...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Chan JK,Manuel MR,Cheung MK,Osann K,Husain A,Teng NN,Rao A,Carlson RW,Whittemore AS

    更新日期:2006-09-01 00:00:00

  • Identification of inguinofemoral lymph node metastases by methylation markers in vulvar cancer.

    abstract:OBJECTIVE:Lymph node status in early-stage vulvar cancer can be accurately assessed by the sentinel-node (SN) procedure. Molecular techniques, such as DNA-methylation assay, might improve SN assessment. In this study, we selected methylation markers for vulvar cancer and determined if these methylation markers were sui...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Oonk MH,Eijsink JJ,Volders HH,Hollema H,Wisman GB,Schuuring E,van der Zee AG

    更新日期:2012-05-01 00:00:00

  • Class II radical hysterectomy shows less morbidity and good treatment efficacy compared to class III.

    abstract::Treatment of 102 patients with cancer of the cervix by class II and III radical hysterectomy was reviewed to compare the operative morbidity and efficacy of class II radical hysterectomy for select cases. Of the 102 patients, 21 had a class II hysterectomy, whereas 81 patients had a class III hysterectomy. The class I...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Photopulos GJ,Zwaag RV

    更新日期:1991-01-01 00:00:00