Malignancy-induced secondary achalasia.


:Secondary achalasia refers to the development of clinical, radiographic, and manometric findings of achalasia as a result of (i.e., secondary to) another underlying disorder. A variety of malignancies have been associated with secondary achalasia. Adenocarcinoma of the esophagogastric junction accounts for the majority of cases of malignancy-induced achalasia, however, noncontiguous tumors may also cause this disorder. Although rare, malignancy-induced achalasia will occasionally be encountered by gastroenterologists and gastrointestinal radiologists who see patients with dysphagia and/or achalasia. Since treatment is aimed at the underlying neoplasm, it is important to recognize this disorder. Three clinical features suggest the possibility of malignancy as a cause of achalasia: 1) short duration of dysphagia (< 1 year); 2) significant weight loss (> 15 pounds); and 3) age > 55 years. The presence of any of these should at least raise a suspicion of malignancy. Diagnosis may not be evident on routine esophagrams and endoscopy, and requires clinical suspicion for further evaluation with thoraco-abdominal CT scanning and endoscopic ultrasonography.






Parkman HP,Cohen S


Has Abstract


1994-04-01 00:00:00












  • Pilot study of 12-month outcomes of nursing home patients with aspiration on videofluoroscopy.

    abstract::The 12-month clinical outcomes of nursing home patients who underwent videofluoroscopic swallowing evaluation was determined. A retrospective review of 40 patients in a teaching nursing home who had videofluoroscopic swallowing studies from 1987 through 1989 was performed. Clinical outcomes measured included feeding t...


    pub_type: 杂志文章


    authors: Croghan JE,Burke EM,Caplan S,Denman S

    更新日期:1994-07-01 00:00:00

  • Surgical treatment for locally advanced (T4) squamous cell carcinoma of the thoracic esophagus.

    abstract::It is still difficult to decide on the treatment modalities for advanced esophageal carcinoma when the prognostic factors of T4 esophageal cancer are not fully understood. In this article, we report that among 71 patients with T4 thoracic esophageal cancer, 49 underwent esophagectomy, 9 had curative resection (R0 grou...


    pub_type: 杂志文章


    authors: Tachibana M,Dhar DK,Kinugasa S,Yoshimura H,Shibakita M,Ohno S,Ueda S,Fujii T,Kohno H,Nagasue N

    更新日期:2002-10-01 00:00:00

  • Swallowing apraxia: a disorder of the Praxis system?

    abstract::The purpose of this review is to evaluate the disorder of swallowing apraxia and determine how it fits into the praxis system. Swallowing apraxia, a proposed disorder of lingual, labial, and mandibular coordination, has been observed before bolus transfer during the oral stage of swallowing. Although frequently discus...


    pub_type: 杂志文章


    authors: Daniels SK

    更新日期:2000-07-01 00:00:00

  • Surface Electromyographic Biofeedback and the Effortful Swallow Exercise for Stroke-Related Dysphagia and in Healthy Ageing.

    abstract::Dysphagia is common after stroke, leading to adverse outcome. The Effortful Swallow (ES) is recommended to improve swallowing but it is not known if dysphagic patients can increase muscle activity during the exercise or if age affects performance. Providing surface electromyographic (sEMG) biofeedback during dysphagia...


    pub_type: 杂志文章


    authors: Archer SK,Smith CH,Newham DJ

    更新日期:2020-05-22 00:00:00

  • Within-Bolus Variability of the Penetration-Aspiration Scale Across Two Subsequent Swallows in Patients with Head and Neck Cancer.

    abstract::To compare two consecutive swallowing attempts to study if there is a difference in Rosenbek's penetration-aspiration scale (PAS) scores between the first and second swallowing attempt of the same bolus type in videofluoroscopic examination of swallowing (VFS). Additional aims include reflecting on which bolus sizes a...


    pub_type: 杂志文章


    authors: Hedström J,Tuomi L,Andersson M,Dotevall H,Osbeck H,Finizia C

    更新日期:2017-10-01 00:00:00

  • Comparison of Two Methods for Inducing Reflex Cough in Patients With Parkinson's Disease, With and Without Dysphagia.

    abstract::Aspiration pneumonia is a common cause of death in people with Parkinson's disease (PD). Dysfunctional swallowing occurs in the majority of people with PD, and research has shown that cough function is also impaired. Previous studies suggest that testing reflex cough by having participants inhale a cough-inducing stim...


    pub_type: 杂志文章


    authors: Hegland KW,Troche MS,Brandimore A,Okun MS,Davenport PW

    更新日期:2016-02-01 00:00:00

  • Characteristics of dysphagia in elderly patients requiring mechanical ventilation.

    abstract::The purpose of this study was to describe the swallowing characteristics of elderly patients requiring mechanical ventilation with tracheostomy admitted to a long-term, acute-care hospital. The study was conducted through retrospective record review of patients on mechanical ventilation who had received a Modified Bar...


    pub_type: 杂志文章


    authors: Davis LA,Thompson Stanton S

    更新日期:2004-01-01 00:00:00

  • Modern solid state computerized manometry of the pharyngoesophageal segment.

    abstract::There has been renewed interest in the use of manometry of the pharyngoesophageal segment in the investigation of pharyngeal dysphagia. Advances in technology have alleviated previous difficulties presented by factors such as the rapid response rate of the striated muscle and asymmetry of the upper esophageal sphincte...


    pub_type: 杂志文章,评审


    authors: Castell JA,Castell DO

    更新日期:1993-01-01 00:00:00

  • Dysphagia in dermatologic disease.

    abstract::Disorders of the oral cavity, pharynx, and esophagus may be found in some dermatologic diseases. The connective tissue diseases especially may be accompanied by dysphagia. Furthermore, some rare inflammatory and bullous dermatologic diseases can lead to esophageal disorders. Finally, some infectious and malignant dise...


    pub_type: 杂志文章,评审


    authors: Bübl R,Schön B

    更新日期:1993-01-01 00:00:00

  • Late Dysphagia and dyspnea as complications of esophagogastroduodenoscopy in delayed pressure urticaria: case report.

    abstract::Delayed pressure urticaria (DPU) is characterized by swelling in the area of sustained pressure on the skin. The reported case was a potentially life-threatening complication due to mucosal edema following esophagogastroduodenoscopy (EGD). A 37-year-old man, suffering from severe DPU and chronic spontaneous urticaria,...


    pub_type: 杂志文章


    authors: Czecior E,Grzanka A,Kurak J,Misiolek M,Kasperska-Zajac A

    更新日期:2012-03-01 00:00:00

  • Effortful swallowing training combined with electrical stimulation in post-stroke dysphagia: a randomized controlled study.

    abstract::We tested the effect of effortful swallow combined with surface electrical stimulation used as a form of resistance training in post-stroke patients with dysphagia. Twenty post-stroke dysphagic patients were randomly divided into two groups: those who underwent effortful swallow with infrahyoid motor electrical stimul...


    pub_type: 杂志文章,随机对照试验


    authors: Park JW,Kim Y,Oh JC,Lee HJ

    更新日期:2012-12-01 00:00:00

  • Economic Analysis of a Three-Arm RCT Exploring the Delivery of Intensive, Prophylactic Swallowing Therapy to Patients with Head and Neck Cancer During (Chemo)Radiotherapy.

    abstract::Research advocates for the use of intensive, prophylactic swallowing therapy to help reduce the severity of dysphagia in patients receiving (chemo)radiotherapy ([C]RT) for head/neck cancer (HNC). Unfortunately, the intensity of this therapy, coupled with growing patient numbers and limited clinical resources, provides...


    pub_type: 杂志文章,随机对照试验


    authors: Wall LR,Kularatna S,Ward EC,Cartmill B,Hill AJ,Isenring E,Byrnes J,Porceddu SV

    更新日期:2019-10-01 00:00:00

  • Effect of aging on the deglutitive oral, pharyngeal, and esophageal motor function.

    abstract::Aging affects some members of the swallowing orchestra and spares the others. It seems that changes in the pharynx of the elderly are more of a positive nature than a negative one and reflect an adaptation to age-induced structural changes of the upper esophageal sphincter. In the esophagus, the positive change in deg...


    pub_type: 杂志文章,评审


    authors: Shaker R,Lang IM

    更新日期:1994-10-01 00:00:00

  • Anterior cervical osteophytes causing dysphagia and dyspnea: an uncommon entity revisited.

    abstract::Large anterior cervical osteophytes can occur in degeneration of the cervical spine or in diffuse idiopathic skeletal hyperostosis (DISH). We present the case of an 83-year-old patient with progressive dysphagia and acute dyspnea, necessitating emergency tracheotomy. Voluminous anterior cervical osteophytes extending ...


    pub_type: 杂志文章


    authors: Giger R,Dulguerov P,Payer M

    更新日期:2006-10-01 00:00:00

  • Kinematic pharyngeal transit times in myopathy: evaluation for dysphagia.

    abstract::Measurement of kinematic pharyngeal transit times, a new videofluoroscopy technique, provides useful quantitative data to supplement the qualitative data previously available from videofluoroscopy swallowing studies. Kinematic pharyngeal transit times have not previously been reported for subjects with myopathy. This ...


    pub_type: 杂志文章


    authors: Johnson ER,McKenzie SW

    更新日期:1993-01-01 00:00:00

  • Relationship Between Laryngeal Sensory Deficits, Aspiration, and Pneumonia in Patients with Dysphagia.

    abstract::The laryngeal adductor reflex (LAR) is an airway protective reflex that manifests as a brief vocal fold closure in response to laryngeal stimulation. This study examined if the absence of the LAR in response to touch delivered by a laryngoscope is associated with penetration/aspiration or pneumonia in patients with dy...


    pub_type: 杂志文章


    authors: Kaneoka A,Pisegna JM,Inokuchi H,Ueha R,Goto T,Nito T,Stepp CE,LaValley MP,Haga N,Langmore SE

    更新日期:2018-04-01 00:00:00

  • A Comparison of Measurements of a Pediatric Supplement.

    abstract::This study evaluated the flow properties of viscosity and flow rate for water and two common pediatric liquids. The flow properties of the test liquids are of interest to create a cup simulation model and "smart" prototype training cup. Two objective methods of determining flow properties were utilized: a rheometer to...


    pub_type: 杂志文章


    authors: Creech TN,Bailey-Van Kuren M,Sparks J,Becker SB,Kou RSN,Wnek OC,Scarborough DR

    更新日期:2019-04-01 00:00:00

  • Silent aspiration: what do we know?

    abstract::Although clinically evident aspiration is common in subjects with dysphagia, a significant proportion may aspirate silently, i.e., without any outward signs of swallowing difficulty. This article reviews the literature on the prevalence, etiology, and prognostic significance of silent aspiration. An electronic databas...


    pub_type: 杂志文章,评审


    authors: Ramsey D,Smithard D,Kalra L

    更新日期:2005-07-01 00:00:00

  • Pharyngeal Swallowing Pressures in Patients with Radiation-Associated Dysphagia.

    abstract::Dysphagia associated with radiotherapy for head and neck cancer is complex and can be difficult to treat. Videofluoroscopic swallow studies (VFSS) are the current gold-standard instrumented swallow assessment. High-resolution manometry (HRM) is an additional approach that provides objective measurements of swallowing-...


    pub_type: 杂志文章


    authors: Schaen-Heacock NE,Jones CA,McCulloch TM

    更新日期:2020-05-15 00:00:00

  • A survey of variables used by speech-language pathologists to assess function and predict functional recovery in oral cancer patients.

    abstract::Oromotor and clinical swallow assessments are routinely performed by speech-language pathologists (SLPs) who see head and neck cancer (HNC) patients. However, the tools used to assess some of these variables vary. SLPs routinely identify and quantify abnormal functioning in order to rehabilitate the patient. However, ...


    pub_type: 杂志文章


    authors: Husaini H,Krisciunas GP,Langmore S,Mojica JK,Urken ML,Jacobson AS,Lazarus CL

    更新日期:2014-06-01 00:00:00

  • Dysphagia and Oral Morbidities in Chemoradiation-Treated Head and Neck Cancer Patients.

    abstract::This study prospectively evaluated relationships between oral morbidities and swallowing ability in head/neck cancer patients following chemoradiation therapy (CRT) and at 3 months following CRT. Thirty patients with confirmed head/neck cancer undergoing chemoradiation were assessed with a battery of swallowing measur...


    pub_type: 杂志文章


    authors: Ihara Y,Crary MA,Madhavan A,Gregorio DC,Im I,Ross SE,Carnaby GD

    更新日期:2018-12-01 00:00:00

  • An in vitro model for studying neuromuscular transmission in the mouse pharynx.

    abstract::The muscles of the pharynx are controlled by networks of neurons under the control of specific regions in the brain stem, which have been fairly well studied. However, the transmission between these neurons and the pharyngeal muscles, at the motor end plates, is less well understood. Therefore, an in vitro model for t...


    pub_type: 杂志文章


    authors: Ekberg O,Ekman M,Eriksson LI,Malm R,Sundman E,Arner A

    更新日期:2009-03-01 00:00:00

  • Oral Alimentation in Neonatal and Adult Populations Requiring High-Flow Oxygen via Nasal Cannula.

    abstract::Use of high-flow oxygen via nasal cannula (HFO2-NC) is increasingly common in intensive care unit (ICU) settings. Despite the critical interface between respiration and swallowing, and the high acuity of patients in ICUs, the impact of HFO2-NC on feeding and swallowing is unknown. The present prospective, single-cente...


    pub_type: 杂志文章


    authors: Leder SB,Siner JM,Bizzarro MJ,McGinley BM,Lefton-Greif MA

    更新日期:2016-04-01 00:00:00

  • Differential Response Pattern of Oropharyngeal Pressure by Bolus and Dry Swallows.

    abstract::The aim of this study was to determine if bolus and dry swallow showed similar pressure changes in the oropharynx using our newly developed device. A unique character of it includes that baropressure can be measured with the sensor being placed in the balloon and can assess the swallowing mechanics in terms of pressur...


    pub_type: 杂志文章


    authors: Hasegawa M,Kurose M,Okamoto K,Yamada Y,Tsujimura T,Inoue M,Sato T,Narumi T,Fujii N,Yamamura K

    更新日期:2018-02-01 00:00:00

  • The Challenges of Esaphagogastric Junction Outflow Obstruction, Is It Really a Diagnosis? Creating a Systematic Clinical Approach for EGJOO.

    abstract::Esophagogastric junction outflow obstruction (EGJOO) is currently diagnosed according to the Chicago Classification V3 by an elevated median integrated relaxation pressure on high resolution manometry. However, EGJOO may not be an accurate diagnosis, as it may be based on abnormal IRP from an artifact, affected by nar...


    pub_type: 杂志文章


    authors: Tadros M,Yodice M

    更新日期:2020-07-16 00:00:00

  • Modulation of activity in swallowing motor cortex following esophageal acidification: a functional magnetic resonance imaging study.

    abstract::Esophageal acid exposure induces sensory and motility changes in the upper gastrointestinal tract; however, the mechanisms involved and the effects on activity in the brain regions that control swallowing are unknown. The aim of this study was to examine functional changes in the cortical swallowing network as a resul...


    pub_type: 杂志文章


    authors: Paine PA,Hamdy S,Chitnis X,Gregory LJ,Giampietro V,Brammer M,Williams S,Aziz Q

    更新日期:2008-06-01 00:00:00

  • Co-occurrence of Dystonic and Dyskinetic Tongue Movements with Oral Apraxia in Post-regression Dysphagia in Classical Rett Syndrome Years of Life 1 Through 5.

    abstract::We do not know the natural history of dysphagia in classical Rett syndrome (RTT) by stage or age. This study investigated swallowing physiology in 23 females ages 1:7 to 5:8 (years, months) with classical Rett syndrome to determine common and distinguishing features of dysphagia in post-regression early Pseudostationa...


    pub_type: 杂志文章


    authors: Abraham SS,Taragin B,Djukic A

    更新日期:2015-04-01 00:00:00

  • Combined neuromuscular electrical stimulation (NMES) with fiberoptic endoscopic evaluation of swallowing (FEES) and traditional swallowing rehabilitation in the treatment of stroke-related dysphagia.

    abstract::Dysphagia is common after stroke. Neuromuscular electrical stimulation (NMES) and fiberoptic endoscopic evaluation of swallowing (FEES) for the treatment of dysphagia have gained in popularity, but the combined application of these promising modalities has rarely been studied. We aimed to evaluate whether combined NME...


    pub_type: 临床试验,杂志文章


    authors: Sun SF,Hsu CW,Lin HS,Sun HP,Chang PH,Hsieh WL,Wang JL

    更新日期:2013-12-01 00:00:00

  • Image-based measurement of post-swallow residue: the normalized residue ratio scale.

    abstract::Post-swallow residue is considered a sign of swallowing impairment. Existing methods for capturing post-swallow residue (perceptual and quantitative) have inherent limitations. We employed several different perceptual and quantitative (ratio) methods for measuring post-swallow residue on the same 40 swallows and addre...


    pub_type: 杂志文章,评审


    authors: Pearson WG Jr,Molfenter SM,Smith ZM,Steele CM

    更新日期:2013-06-01 00:00:00

  • Clinical validity of the SWAL-QOL and SWAL-CARE outcome tools with respect to bolus flow measures.

    abstract::The aim of this study was to quantify the association between a dysphagia-specific quality of life (SWAL-QOL) and quality of care (SWAL-CARE) questionnaire and four measures of bolus flow. Three hundred eighty-six people with oropharyngeal dysphagia completed a videofluoroscopic examination of their swallowing structu...


    pub_type: 杂志文章


    authors: McHorney CA,Martin-Harris B,Robbins J,Rosenbek J

    更新日期:2006-07-01 00:00:00