The effects of lateral geniculate nucleus, area V4, and middle temporal (MT) lesions on visually guided eye movements.

Abstract:

:Visually guided saccadic eye movements to singly presented stationary targets form a bimodal distribution. After superior colliculus lesions, the so called "express saccades" that form the first mode of the distribution are no longer obtained. The aim of this study was to determine what role several other neural systems play in the generation of express and regular saccades, with the latter being those that form the second mode in the bimodal distribution. Lesions were made in the parvocellular and magnocellular portions of the lateral geniculate nucleus to disrupt either the midget system or the parasol system that originates in the retina and areas V4 and MT. The effects of the lesions were examined on the accuracy and latency of saccadic eye movements made to stationary and to moving visual targets. Following magnocellular and MT lesions deficits were observed in smooth pursuit and in the amplitude of saccades made to moving targets. However, none of the lesions produced significant changes in the bimodal distribution of saccadic latencies to stationary targets. The results suggest that express saccades and regular saccades are not selectively mediated by either the midget or the parasol systems or by areas V4 and MT. Neither are the frontal eye fields involved as had previously been shown. We suggest that the superior colliculus plays a central role in producing both express and regular saccades by virtue of highly convergent input from numerous cortical structures.

journal_name

Vis Neurosci

journal_title

Visual neuroscience

authors

Schiller PH,Lee K

doi

10.1017/s0952523800001590

subject

Has Abstract

pub_date

1994-03-01 00:00:00

pages

229-41

issue

2

eissn

0952-5238

issn

1469-8714

pii

S0952523800001590

journal_volume

11

pub_type

杂志文章
  • Strain variations in cone wavelength peaks in situ during zebrafish development.

    abstract::There are four cone morphologies in zebrafish, corresponding to UV (U), blue (B), green (G), and red (R)-sensing types; yet genetically, eight cone opsins are expressed. How eight opsins are physiologically siloed in four cone types is not well understood, and in larvae, cone physiological spectral peaks are unstudied...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523819000075

    authors: Nelson RF,Balraj A,Suresh T,Torvund M,Patterson SS

    更新日期:2019-07-30 00:00:00

  • Eel visual pigments revisited: the fate of retinal cones during metamorphosis.

    abstract::During their complex life history, anguilliform eels go through a major metamorphosis when developing from a fresh water yellow eel into a deep-sea silver eel. In addition to major changes in body morphology, the visual system also adapts from a fresh water teleost duplex retina with rods and cones, to a specialized d...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523808080152

    authors: Bowmaker JK,Semo M,Hunt DM,Jeffery G

    更新日期:2008-05-01 00:00:00

  • Visual cortex damage-induced growth of retinal axons into the lateral posterior nucleus of the cat.

    abstract::Ablation of visual cortical areas 17 and 18 in neonatal and young adult cats induces novel retinal projections to terminate bilaterally in the lateral posterior nucleus (LP) at a position ventromedial from the medial interlaminar nucleus. Comparison with the visual-field maps of LP indicate that the terminations are f...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800005435

    authors: Payne BR,Foley HA,Lomber SG

    更新日期:1993-07-01 00:00:00

  • Dissociating early and late visual processing via the Ebbinghaus illusion.

    abstract::Visual perception is not instantaneous; the perceptual representation of our environment builds up over time. This can strongly affect our responses to visual stimuli. Here, we study the temporal dynamics of visual processing by analyzing the time course of priming effects induced by the well-known Ebbinghaus illusion...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523816000134

    authors: Schmidt F,Weber A,Haberkamp A

    更新日期:2016-01-01 00:00:00

  • Two opposite effects of ATP on the apparent sensitivity of the cGMP-gated channel of the carp retinal cone.

    abstract::Effects of ATP on the activity of cGMP-gated channels from carp cone photoreceptors were studied. In 29% of the patches examined (N = 45), ATP (1 mM) enhanced a current evoked by cGMP (20 microM, up to about 100%), in 33%. ATP suppressed it by up to about 90%, and in the remaining 38%, ATP had no effect. ATP showed si...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800012578

    authors: Watanabe S,Shen J

    更新日期:1997-07-01 00:00:00

  • Spatio-temporal characterization of retinal opsin gene expression during thyroid hormone-induced and natural development of rainbow trout.

    abstract::The abundance and spatial distribution of retinal cone photoreceptors change during thyroid hormone (TH)-induced and natural development of rainbow trout (Oncorhynchus mykiss). These changes are thought to allow the fish to adapt to different photic environments throughout its life history. To date, the ontogeny of ra...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523806232139

    authors: Veldhoen K,Allison WT,Veldhoen N,Anholt BR,Helbing CC,Hawryshyn CW

    更新日期:2006-03-01 00:00:00

  • Receptive-field properties of Q retinal ganglion cells of the cat.

    abstract::The goal of this work was to provide a detailed quantitative description of the receptive-field properties of one of the types of rarely encountered retinal ganglion cells of cat; the cell named the Q-cell by Enroth-Cugell et al. (1983). Quantitative comparisons are made between the discharge statistics and between th...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800007975

    authors: Troy JB,Schweitzer-Tong DE,Enroth-Cugell C

    更新日期:1995-03-01 00:00:00

  • Striate cortex increases contrast gain of macaque LGN neurons.

    abstract::Recurrent projections comprise a universal feature of cerebral organization. Here, we show that the corticofugal projections from the striate cortex (VI) to the lateral geniculate nucleus (LGN) robustly and multiplicatively enhance the responses of parvocellular neurons, stimulated by gratings restricted to the classi...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800174012

    authors: Przybyszewski AW,Gaska JP,Foote W,Pollen DA

    更新日期:2000-07-01 00:00:00

  • Distributed spatial coding in the superior colliculus: a review.

    abstract::This paper reviews evidence that the superior colliculus (SC) of the midbrain represents visual direction and certain aspects of saccadic eye movements in the distribution of activity across a population of cells. Accurate and precise eye movements appear to be mediated, in part at least, by cells of the SC that have ...

    journal_title:Visual neuroscience

    pub_type: 杂志文章,评审

    doi:10.1017/s0952523800000857

    authors: McIlwain JT

    更新日期:1991-01-01 00:00:00

  • The topography of rod and cone photoreceptors in the retina of the ground squirrel.

    abstract::The distributions of rod and cone photoreceptors have been determined in the retina of the California ground squirrel, Spermophilus beecheyi. Retinas were fixed by perfusion and the rods and cones were detected with indirect immunofluorescence using opsin antibodies. Local densities were determined at 2-mm intervals a...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523898154081

    authors: Kryger Z,Galli-Resta L,Jacobs GH,Reese BE

    更新日期:1998-07-01 00:00:00

  • Simulation of an anatomically defined local circuit: the cone-horizontal cell network in cat retina.

    abstract::The outer plexiform layer of the retina contains a neural circuit in which cone synaptic terminals are electrically coupled and release glutamate onto wide-field and narrow-field horizontal cells. These are also electrically coupled and feed back through a GABAergic synapse to cones. In cat this circuit's structure is...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800008440

    authors: Smith RG

    更新日期:1995-05-01 00:00:00

  • Light-sensitive melatonin synthesis by Xenopus photoreceptors after destruction of the inner retina.

    abstract::Several lines of evidence indicate that retinal photoreceptors produce melatonin. However, there are other potential melatonin sources in the retina, and melatonin synthesis can be regulated by feedback from the inner retina. To analyze cellular mechanisms of melatonin regulation in retinal photoreceptors, we have dev...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800005009

    authors: Cahill GM,Besharse JC

    更新日期:1992-05-01 00:00:00

  • Distribution of GABA immunoreactivity in the cat retina: a light- and electron-microscopic study.

    abstract::The distribution of GABA-like immunoreactivity in the cat retina was studied through the use of preembedding immunocytochemistry for light microscopy and by postembedding immunogold techniques for electron microscopy. Staining was observed in both inner and outer plexiform layers. Approximately 30% of the somata in th...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800012323

    authors: Pourcho RG,Owczarzak MT

    更新日期:1989-01-01 00:00:00

  • Effects of brief monocular deprivation on binocular depth perception in the cat: a sensitive period for the loss of stereopsis.

    abstract::The period of susceptibility for binocular depth vision was studied in kittens by subjecting them to periods of monocular deprivation beginning at different ages. In an initial study, we found that normally reared kittens can learn a depth-discrimination task much more rapidly when tested binocularly than monocularly,...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800000341

    authors: Timney B

    更新日期:1990-09-01 00:00:00

  • Contrast adaptation in retinal and cortical evoked potentials: no adaptation to low spatial frequencies.

    abstract::Contrast adaptation occurs in both the retina and the cortex. Defining its spatial dependence is crucial for understanding its potential roles. We thus asked to what degree contrast adaptation depends on spatial frequency, including cross-adaptation. Measuring the pattern electroretinogram (PERG) and the visual evoked...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523802195095

    authors: Heinrich TS,Bach M

    更新日期:2002-09-01 00:00:00

  • Temporal properties of surround suppression in cat primary visual cortex.

    abstract::The responses of neurons in primary visual cortex (V1) are suppressed by stimuli presented in the region surrounding the receptive field. There is debate as to whether this surround suppression is due to intracortical inhibition, is inherited from lateral geniculate nucleus (LGN), or is due to a combination of these f...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523807070563

    authors: Durand S,Freeman TC,Carandini M

    更新日期:2007-09-01 00:00:00

  • Minimum-variance cone-excitation ratios and the limits of relational color constancy.

    abstract::Relational color constancy refers to the constancy of the perceived relations between the colors of surfaces of a scene under changes in the spectral composition of the illuminant. Spatial ratios of cone excitations provide a natural physical basis for this constancy, as, on average, they are almost invariant under il...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s095252380421327x

    authors: Nascimento SM,de Almeida VM,Fiadeiro PT,Foster DH

    更新日期:2004-05-01 00:00:00

  • Cortical projections to anterior inferior temporal cortex in infant macaque monkeys.

    abstract::Inferior temporal (IT) cortex is a "high-order" region of extrastriate visual cortex important for visual form perception and recognition in adult primates. The pattern of cortical afferents from both ipsilateral and contralateral hemispheres to anterior IT cortex was determined in infant macaque monkeys 7-18 weeks of...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800011160

    authors: Rodman HR,Consuelos MJ

    更新日期:1994-01-01 00:00:00

  • Development of sensitivity to visual motion in macaque monkeys.

    abstract::The development of spatial vision is relatively well documented in human and nonhuman primates. However, little is known about the development of sensitivity to motion. We measured the development of sensitivity to direction of motion, and the relationship between motion and contrast sensitivity in macaque monkeys as ...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523804216054

    authors: Kiorpes L,Movshon JA

    更新日期:2004-11-01 00:00:00

  • Psychophysical analysis of contrast processing segregated into magnocellular and parvocellular systems in asymptomatic carriers of 11778 Leber's hereditary optic neuropathy.

    abstract::We examined achromatic contrast discrimination in asymptomatic carriers of 11778 Leber's hereditary optic neuropathy (LHON 18 controls) and 18 age-match were also tested. To evaluate magnocellular (MC) and Parvocellular (PC) contrast discrimination, we used a version of Pokorny and Smith's (1997) pulsed/steady-pedesta...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523808080462

    authors: Gualtieri M,Bandeira M,Hamer RD,Costa MF,Oliveira AG,Moura AL,Sadun F,De Negri AM,Berezovsky A,Salomão SR,Carelli V,Sadun AA,Ventura DF

    更新日期:2008-05-01 00:00:00

  • Linking perception to neural activity as measured by visual evoked potentials.

    abstract::Linking propositions have played an important role in refining our understanding of the relationship between neural activity and perception. Over the last 40 years, visual evoked potentials (VEPs) have been used in many different ways to address questions of the relationship between neural activity and perception. Thi...

    journal_title:Visual neuroscience

    pub_type: 杂志文章,评审

    doi:10.1017/S0952523813000205

    authors: Norcia AM

    更新日期:2013-11-01 00:00:00

  • Excitation and inhibition in orientation selectivity of cat visual cortex neurons revealed by whole-cell recordings in vivo.

    abstract::One striking transformation in response properties that occurs in the geniculo-cortical pathway is the appearance of a high degree of orientation selectivity in the cortex. This property may be conceived as arising purely from the excitatory inputs to the cell, as being structured largely by the inhibition a cortical ...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800010257

    authors: Volgushev M,Pei X,Vidyasagar TR,Creutzfeldt OD

    更新日期:1993-11-01 00:00:00

  • Evoked potential and psychophysical analysis of Fourier and non-Fourier motion mechanisms.

    abstract::Some visual stimuli produce a strong percept of motion, even though they fail to excite motion detectors based on Fourier energy or cross correlation. Models which suffice to explain the motion percept in these non-Fourier motion (NFM) stimuli include linear spatiotemporal filtering, followed by rectification, followe...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800009573

    authors: Victor JD,Conte MM

    更新日期:1992-08-01 00:00:00

  • The relationship between GABA-containing cells and the cholinergic circuitry in the rabbit retina.

    abstract::As a part of ongoing efforts to understand the cholinergic circuitry in the mammalian retina, we studied the coexpression of nicotinic acetylcholine receptors (nAChRs) and gamma-aminobutyric acid (GABA), the GABA transporter 1 (GAT-1), or choline acetyltransferase (ChAT) immunoreactivity in the rabbit retina. Double-l...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523801181083

    authors: Dmitrieva NA,Lindstrom JM,Keyser KT

    更新日期:2001-01-01 00:00:00

  • Development of multibank rod retinae in deep-sea fishes.

    abstract::We studied the development of multibank rod retinae by monitoring the size-related addition of new layers of rod inner and outer segments in four species of deep-sea fishes and found two different growth paradigms. In the mesopelagic Chauliodus sloani, new banks of rod inner and outer segments are added as long as the...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s095252389815304x

    authors: Fröhlich E,Wagner HJ

    更新日期:1998-05-01 00:00:00

  • Beta-ionone activates and bleaches visual pigment in salamander photoreceptors.

    abstract::Vision begins with photoisomerization of 11-cis retinal to the all-trans conformation within the chromophore-binding pocket of opsin, leading to activation of a biochemical cascade. Release of all-trans retinal from the binding pocket curtails but does not fully quench the ability of opsin to activate transducin. All-...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523809090105

    authors: Isayama T,McCabe England SL,Crouch RK,Zimmerman AL,Makino CL

    更新日期:2009-05-01 00:00:00

  • Contrast discrimination: a model and a hypothesis concerning the role of cholinergic modulation in contrast perception.

    abstract::A model of contrast discrimination performance in human observers is developed and then extended to cover effects on performance of anticholinergic drugs. It is shown that it is necessary to assume that neural noise increases at high spatial frequencies in order to provide a satisfactory model of variations in discrim...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800009123

    authors: Smith AT

    更新日期:1996-09-01 00:00:00

  • Photoreceptor distribution in the retina of adult Pacific salmon: corner cones express blue opsin.

    abstract::The retina of salmonid fishes has two types of cone photoreceptors: single and double cones. At the nuclear level, these cones are distributed in a square mosaic such that the double cones form the sides of the square and the single cones occupy positions at the centre and at the corners of the square. Double cones co...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523807070137

    authors: Cheng CL,Flamarique IN

    更新日期:2007-05-01 00:00:00

  • Current source-density analysis of light-evoked field potentials in rabbit retina.

    abstract::The technique of current source-density analysis was applied to several components of the light-evoked field potentials (electroretinogram) from the retina of the superfused eyecup of rabbit. The depth distributions of the major current sources and sinks were: b-wave--sink at outer plexiform layer, source at inner ple...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523899162163

    authors: Karwoski CJ,Xu X

    更新日期:1999-03-01 00:00:00

  • Rescue of excitation by inositol following Li(+)-induced block in Limulus ventral photoreceptors.

    abstract::The phosphoinositide (PI) intracellular signaling pathway, which triggers Ca2+ release from intracellular stores, appears to be a central feature of phototransduction in most invertebrate species studied. Procedures designed to inhibit PI-pathway reactions cause suppression of excitation to dim lights. However, in Lim...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523898151076

    authors: Johnson EC,Gray-Keller MP,O'Day PM

    更新日期:1998-01-01 00:00:00