Differential effects of lesions of the dorsomedial and dorsolateral caudate-putamen on reaction time performance in rats.


:In order to investigate the role of the dorsomedial and dorsolateral caudate-putamen (CPu) in movement initiation of rats, we examined the effects of quinolinic acid lesions (30 nmol in 1 microliter) in these striatal subregions in a simple reaction time task. Results show that lesions of the dorsomedial, but not of the dorsolateral CPu increased reaction times. These findings provide further evidence for a functional heterogenity of the CPu and demonstrate an involvement of the dorsomedial CPu in processes related to rapid initiation of responses.


Behav Brain Res


Hauber W,Schmidt WJ




Has Abstract


1994-02-28 00:00:00














  • Metabolic syndrome accentuates post-traumatic stress disorder-like symptoms and glial activation.

    abstract::The relationship between individuals with post-traumatic stress disorder (PTSD) and the development of metabolic syndrome (MS) is well understood, but the relationship between individuals with preexisting MS and the development of PTSD is not yet known. Therefore, we evaluated the course of PTSD development in preexis...

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Alves Freire Ribeiro AC,Batista TH,Trujillo Rojas VC,Giusti-Paiva A,Cardoso Vilela F

    更新日期:2020-04-20 00:00:00

  • Conservative motor systems, behavioral modulation and neural plasticity.

    abstract::Neural plasticity is a term that encompasses a vast array of changes in the nervous system in response to a wide range of environmental disturbances. The conservative manner in which nervous systems produce behavior is explored in the act of scratching the head. Whether the scratching is done with the hind leg (flamin...

    journal_title:Behavioural brain research

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    authors: Pellis SM

    更新日期:2010-12-06 00:00:00

  • Serotonin transporter knockout and repeated social defeat stress: impact on neuronal morphology and plasticity in limbic brain areas.

    abstract::Low expression of the human serotonin transporter (5-HTT) gene presumably interacts with stressful life events enhancing susceptibility for affective disorders. 5-Htt knockout (KO) mice display an anxious phenotype, and behavioural differences compared to wild-type (WT) mice are exacerbated after repeated loser experi...

    journal_title:Behavioural brain research

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    authors: Nietzer SL,Bonn M,Jansen F,Heiming RS,Lewejohann L,Sachser N,Asan ES,Lesch KP,Schmitt AG

    更新日期:2011-06-20 00:00:00

  • Effects of reversible inactivation of the medial septum on rat exploratory behavior in the elevated plus-maze using a test-retest paradigm.

    abstract::The effect of intraseptal injections of lidocaine before a first or a second session in the elevated plus-maze, in a test-retest paradigm, was investigated. In addition to gross session analyses, a minute-by-minute analysis of the sessions was used to evaluate both anxiety and memory. Lidocaine injections before the t...

    journal_title:Behavioural brain research

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    authors: Lamprea MR,Garcia AM,Morato S

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  • Reversal of prenatal diazepam-induced deficit in a spatial-object learning task by brief, periodic maternal separation in adult rats.

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    journal_title:Behavioural brain research

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    authors: Cannizzaro E,Martire M,Gagliano M,Plescia F,La Barbera M,Mantia G,Mineo A,Cannizzaro G,Cannizzaro C

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  • Understanding behavioral and physiological phenotypes of stress and anxiety in zebrafish.

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    journal_title:Behavioural brain research

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  • Mediodorsal thalamic lesions block the stress-induced inversion of serial memory retrieval pattern in mice.

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    journal_title:Behavioural brain research

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    authors: Chauveau F,Piérard C,Corio M,Célérier A,Christophe T,Vouimba RM,Guillou JL,Béracochéa D

    更新日期:2009-11-05 00:00:00

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    journal_title:Behavioural brain research

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    authors: Chen W,Shields J,Huang W,King JA

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    authors: Alleva L,Tirelli E,Brabant C

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  • Electrolytic lesions of a discrete area within the nucleus accumbens shell attenuate the long-term expression, but not early phase, of sensitization to cocaine.

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    journal_title:Behavioural brain research

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    authors: Haghparast A,Farzin D,Ordikhani-Seyedlar M,Motaman S,Kermani M,Azizi P

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    authors: Dal-Zotto S,Martí O,Armario A

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    journal_title:Behavioural brain research

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    journal_title:Behavioural brain research

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    authors: van den Buuse M

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    更新日期:2003-05-15 00:00:00

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    journal_title:Behavioural brain research

    pub_type: 杂志文章,评审


    authors: Sprick U

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  • Flupirtine attenuates chronic restraint stress-induced cognitive deficits and hippocampal apoptosis in male mice.

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    authors: Huang P,Li C,Fu T,Zhao D,Yi Z,Lu Q,Guo L,Xu X

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    authors: Allahverdiyev O,Nurten A,Enginar N

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    journal_title:Behavioural brain research

    pub_type: 杂志文章,评审


    authors: Snyder JS,Cameron HA

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  • Telemetrically recorded neuronal activity in the inferior colliculus and bordering tegmentum during vocal communication in squirrel monkeys (Saimiri sciureus).

    abstract::In order to find out whether the inferior colliculus, in addition to its auditory decoding function, also has an auditory gating function in the sense that it treats self-produced sounds differently from external ones, we have explored the inferior colliculus and bordering tegmentum for neurones reacting differently t...

    journal_title:Behavioural brain research

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    authors: Tammer R,Ehrenreich L,Jürgens U

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  • Effect of disconnecting the orbital prefrontal cortex from the nucleus accumbens core on inter-temporal choice behaviour: a quantitative analysis.

    abstract::Previous experiments showed that destruction of the orbital prefrontal cortex (OPFC) or the nucleus accumbens core (AcbC) in rats altered choice between two delayed food reinforcers. Application of a quantitative model of inter-temporal choice suggested that lesions of either structure increased the delay-dependent de...

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Bezzina G,Body S,Cheung TH,Hampson CL,Bradshaw CM,Szabadi E,Anderson IM,Deakin JF

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  • Impaired cognitive flexibility during sleep deprivation among carriers of the Brain Derived Neurotrophic Factor (BDNF) Val66Met allele.

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    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Grant LK,Cain SW,Chang AM,Saxena R,Czeisler CA,Anderson C

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  • Methylphenidate has long-lasting metaplastic effects in the prefrontal cortex of adolescent rats.

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    journal_title:Behavioural brain research

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    authors: Powell AL,Nelson AJD,Hindley E,Davies M,Aggleton JP,Vann SD

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    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Avni R,Zadicario P,Eilam D

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  • Genetic dissection of nicotine-related behaviour: a review of animal studies.

    abstract::Nicotine has a broad spectrum of behavioural effects. A considerable body of data has emerged indicating genetic factors regulate the behavioural effects of nicotine. Experimental genetic techniques have been invaluable in generating knowledge on the interrelationship of genetic factors and behavioural responsiveness ...

    journal_title:Behavioural brain research

    pub_type: 杂志文章,评审


    authors: Mohammed AH

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  • A new proposal for drug conditioning with implications for drug addiction: the Pavlovian two-step from delay to trace conditioning.

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    journal_title:Behavioural brain research

    pub_type: 杂志文章,评审


    authors: Carey RJ,Carrera MP,Damianopoulos EN

    更新日期:2014-12-15 00:00:00