Temporin A soaking in combination with intraperitoneal linezolid prevents vascular graft infection in a subcutaneous rat pouch model of infection with Staphylococcus epidermidis with intermediate resistance to glycopeptides.

Abstract:

:The efficacy of linezolid and temporin A in the prevention of prosthetic graft infection due to methicillin-resistant Staphylococcus epidermidis with intermediate resistance to glycopeptides was investigated in a subcutaneous rat pouch model. Linezolid and temporin A, alone or combined, greatly reduced the bacterial numbers compared to the effect with control drugs.

authors

Giacometti A,Cirioni O,Ghiselli R,Orlando F,D'Amato G,Kamysz W,Mocchegiani F,Sisti V,Silvestri C,Łukasiak J,Rocchi M,Saba V,Scalise G

doi

10.1128/AAC.48.8.3162-3164.2004

subject

Has Abstract

pub_date

2004-08-01 00:00:00

pages

3162-4

issue

8

eissn

0066-4804

issn

1098-6596

pii

48/8/3162

journal_volume

48

pub_type

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