Anticonvulsant drugs affect particular steps of verbal memory processing--an evaluation of 13 patients with intractable complex partial seizures of left temporal lobe origin.


:Thirteen patients with intractable complex partial seizures of left temporal lobe origin were tested for verbal memory performance under the conditions of full and reduced anticonvulsant medication. As suggested by previous investigations memory performance improved significantly with the reduction of anticonvulsants. However, our observations refute assumptions that the effects of antiepileptic drugs act primarily by non-specific mechanisms affecting attention and/or memory diffusely. Our data rather suggest that very specific and circumscribed steps of verbal memory processing, particularly retrieval abilities after interference, are affected by anticonvulsants. The possible implications of these findings in relation to morphological and electrophysiological aspects in patients with temporal lobe epilepsy are discussed.






Durwen HF,Hufnagel A,Elger CE




Has Abstract


1992-07-01 00:00:00












  • Emotion and cognition and the amygdala: from "what is it?" to "what's to be done?".

    abstract::The amygdala is a fascinating, complex structure that lies at the center of much of our current thinking about emotion. Here, I will review data that suggest that the amygdala is involved in several processes linked to determining what a stimulus is and what the organism should therefore do - the two questions that ar...


    pub_type: 杂志文章,评审


    authors: Pessoa L

    更新日期:2010-10-01 00:00:00

  • The effects of working memory load on visual awareness and its electrophysiological correlates.

    abstract::Consciousness and working memory (WM) have been thought to be closely related, but their exact relationship has remained unclear. The present study focused on the question whether visual awareness, the subjective experience of seeing, depends on resources of WM. Three dual-task experiments were run. The participants w...


    pub_type: 杂志文章


    authors: Koivisto M,Ruohola M,Vahtera A,Lehmusvuo T,Intaite M

    更新日期:2018-11-01 00:00:00

  • Level of uncertainty about the affective nature of a pictorial stimulus influences anticipatory neural processes: An event-related potential (ERP) study.

    abstract::Uncertainty about the emotional impact of future events is a common part of everyday life. However, relatively little is known about whether the level of uncertainty about the affective nature of an upcoming visual image influences anticipatory neurocognitive processes. To investigate this, participants viewed a serie...


    pub_type: 杂志文章


    authors: Johnen AK,Harrison NR

    更新日期:2020-09-01 00:00:00

  • Overweight adults are more impulsive than normal weight adults: Evidence from ERPs during a chocolate-related delayed discounting task.

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    pub_type: 杂志文章


    authors: Liu Y,Zhao J,Zhang X,Gao X,Xu W,Chen H

    更新日期:2019-10-01 00:00:00

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    pub_type: 杂志文章


    authors: Michelon P,Biederman I

    更新日期:2003-01-01 00:00:00

  • Developmental dyslexia: passive visual stimulation provides no evidence for a magnocellular processing defect.

    abstract::Livingstone et al. [Livingstone, M. S., Rosen, G. D., Drislane, F. W. and Galaburda, A. M. Physiological and anatomical evidence for a magnocellular defect in developmental dyslexia. Proceedings of the National Academy of Science U.S.A. 88, 7943-7947, 1991] presented evidence for a defect of the magnocellular visual p...


    pub_type: 杂志文章


    authors: Johannes S,Kussmaul CL,Münte TF,Mangun GR

    更新日期:1996-11-01 00:00:00

  • Gender differences in neural-behavioral response to self-observation during a novel fMRI social stress task.

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    pub_type: 杂志文章


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    更新日期:2014-01-01 00:00:00

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    pub_type: 杂志文章


    authors: Ueno T,Mate J,Allen RJ,Hitch GJ,Baddeley AD

    更新日期:2011-05-01 00:00:00

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    authors: Kumaran D,Hassabis D,Spiers HJ,Vann SD,Vargha-Khadem F,Maguire EA

    更新日期:2007-09-20 00:00:00

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    authors: Koh HC,Milne E,Dobkins K

    更新日期:2010-12-01 00:00:00

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    pub_type: 杂志文章


    authors: Li L,Abutalebi J,Zou L,Yan X,Liu L,Feng X,Wang R,Guo T,Ding G

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    pub_type: 杂志文章


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    pub_type: 杂志文章,评审


    authors: Paus T

    更新日期:1996-06-01 00:00:00

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    pub_type: 杂志文章


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    pub_type: 临床试验,杂志文章


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    pub_type: 杂志文章,评审


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    pub_type: 杂志文章


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    pub_type: 杂志文章


    authors: Zimmer U,Lewald J,Erb M,Karnath HO

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    pub_type: 杂志文章


    authors: Meenan JP,Miller LA

    更新日期:1994-09-01 00:00:00

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    pub_type: 杂志文章


    authors: Mei D,Zhang W,Yin L

    更新日期:2020-03-02 00:00:00

  • Evidence for asymmetric frontal-lobe involvement in episodic memory from functional magnetic resonance imaging and patients with unilateral frontal-lobe excisions.

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    authors: Lee AC,Robbins TW,Smith S,Calvert GA,Tracey I,Matthews P,Owen AM

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    authors: Cheng D,Zhou A,Yu X,Chen C,Jia J,Zhou X

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    pub_type: 杂志文章


    authors: Myers EB

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    pub_type: 杂志文章


    authors: Ponton CW

    更新日期:1987-01-01 00:00:00

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    pub_type: 杂志文章


    authors: Kwok SC,Shallice T,Macaluso E

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    pub_type: 杂志文章


    authors: Foster SM,Kisley MA,Davis HP,Diede NT,Campbell AM,Davalos DB

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    pub_type: 杂志文章


    authors: Beaty RE,Benedek M,Wilkins RW,Jauk E,Fink A,Silvia PJ,Hodges DA,Koschutnig K,Neubauer AC

    更新日期:2014-11-01 00:00:00