Abstract:
:An identical CRF-related diuretic peptide (Musca-DP) was isolated and characterized from whole-body extracts of the house fly, Musca domestica, and stable fly, Stomoxys calcitrans. The peptide stimulates cyclic AMP production in Manduca sexta Malpighian tubules and increases the rate of fluid secretion by isolated Musca domestica tubules. The 44-residue peptide, with a mol.wt. of 5180, is amidated, and has the primary structure: NKPSLSIVNPLDVLRQRLLLEIARRQMKENTRQVELNRAILKNV-NH2. Musca-DP has a high percentage of sequence identity with other characterized CRF-related insect diuretic peptides.
journal_name
Peptidesjournal_title
Peptidesauthors
Clottens FL,Holman GM,Coast GM,Totty NF,Hayes TK,Kay I,Mallet AI,Wright MS,Chung JS,Truong Odoi
10.1016/0196-9781(94)90059-0subject
Has Abstract,Author List Incompletepub_date
1994-01-01 00:00:00pages
971-9issue
6eissn
0196-9781issn
1873-5169pii
0196-9781(94)90059-0journal_volume
15pub_type
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